[
  {
    "phenotype_id": "PH642",
    "phenotype_version_id": 1284,
    "name": "Beta Blockers",
    "definition": "Objectives: \n\nTo conduct a fully independent, external validation of a research study based on one electronic health record database using a different database sampling from the same population.\n\n\nDesign: \n\nRetrospective cohort analysis of β-blocker therapy and all-cause mortality in patients with cancer.\n\n\nSetting: \n\nTwo UK national primary care databases (PCDs): the Clinical Practice Research Datalink (CPRD) and Doctors’ Independent Network (DIN).\n\n\nParticipants: \n\nCPRD data for 11 302 patients with cancer compared with published results from DIN for 3462 patients; study period January 1997 to December 2006.\n\n\nPrimary and secondary outcome measures:\n\nAll-cause mortality: overall; by treatment subgroup (β-blockers only, β-blockers plus other blood pressure lowering medicines (BPLM), other BPLMs only); and by cancer site.\n\n\nResults: \n\nUsing CPRD, β-blocker use was not associated with mortality (HR=1.03, 95% CI 0.93 to 1.14, vs patients prescribed other BPLMs only), but DIN β-blocker users had significantly higher mortality (HR=1.18, 95% CI 1.04 to 1.33). However, these HRs were not statistically different (p=0.063), but did differ for patients on β-blockers alone (CPRD=0.94, 95% CI 0.82 to 1.07; DIN=1.37, 95% CI 1.16 to 1.61; p<0.001). Results for individual cancer sites differed by study, but only significantly for prostate and pancreas cancers. Results were robust under sensitivity analyses, but we could not be certain that mortality was identically defined in both databases.\n\n\nConclusions: \n\nWe found a complex pattern of similarities and differences between databases. Overall treatment effect estimates were not statistically different, adding to a growing body of evidence that different UK PCDs produce comparable effect estimates. However, individually the two studies lead to different conclusions regarding the safety of β-blockers and some subgroup effects differed significantly. Single studies using even internally wellvalidated databases do not guarantee generalisable results, especially for subgroups, and confirmatory studies using at least one other independent data source are strongly recommended.\n\n\n\n\n\n\n\n\n",
    "implementation": "",
    "publications": [
      {
        "doi": null,
        "details": "David A Springate, Darrent M Aschroft, Evangelos Kontopantelis, Tim Doran, Ronan Ryan, David Reeves, Can analyses of electronic patient records be independently and externally validated? Study 2—the effect of β-adrenoceptor blocker therapy on cancer survival a retrospective cohort study. BMJ Open, 5(e007299), 2014."
      }
    ],
    "validation": "",
    "citation_requirements": "",
    "created": "2021-10-06T16:28:13.555895Z",
    "author": "David A Springate, Darren M Aschroft, Evangelos Kontopantelis, Tim Doran, Ronan Ryan, David Reeves",
    "collections": [
      {
        "name": "ClinicalCodes Repository",
        "value": 25
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": null,
    "world_access": 1,
    "updated": "2021-10-06T16:28:13.555923Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Drug",
        "value": "3"
      }
    ],
    "ontology": null,
    "phenoflowid": "",
    "data_sources": [
      {
        "name": "CPRD GOLD",
        "value": 5,
        "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f",
        "url": "https://healthdatagateway.org/en/dataset/694",
        "datasource_id": 694
      },
      {
        "name": "Doctors Independent Network",
        "value": 28,
        "uid": "",
        "url": "",
        "datasource_id": 28
      }
    ],
    "coding_system": [
      {
        "name": "GPRD product codes",
        "value": 14
      }
    ],
    "event_date_range": "01/01/19997 - 31/12/2006",
    "concept_information": [
      {
        "concept_id": 2062,
        "concept_version_id": 5262,
        "concept_name": "Beta Blockers - Primary Care",
        "coding_system": {
          "id": 14,
          "name": "GPRD product codes",
          "description": "GPRD product codes"
        },
        "phenotype_id": "PH642",
        "phenotype_version_id": 1284,
        "phenotype_name": "Beta Blockers",
        "code_attribute_header": [
          "Coding System (CPRD_product_code)",
          "Entity type",
          "Category"
        ],
        "codes": [
          {
            "code": "1006",
            "description": "HALF-INDERAL LA capsules 80mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "10191",
            "description": "ATENIX tablets 50mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "10294",
            "description": "INDERAL injection 1mg/ml [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "10429",
            "description": "LOPRESOR tablets 50mg [NOVARTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1048",
            "description": "INDERAL tablets 80mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1050",
            "description": "INDERAL tablets 40mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "10627",
            "description": "CO-BETALOC tablets 100mg + 12.5mg [PHARMACIA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "10716",
            "description": "CORGARD tablets 80mg [SANOFI/AVE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "10777",
            "description": "TRASICOR tablets 160mg [NOVARTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "10892",
            "description": "EMCOR tablets 10mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1124",
            "description": "TENORETIC tablets 100mg + 25mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "11338",
            "description": "bendroflumethiazide with nadolol tablets 5mg + 40mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "11380",
            "description": "SOTACOR tablets 160mg [BRISTOL]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "11711",
            "description": "propranolol oral solution 50mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "11793",
            "description": "metoprolol tartrate suspension 50mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12037",
            "description": "BETIM tablets 10mg [ICN]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12054",
            "description": "propranolol with bendroflumethiazide capsules 80mg + 2.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12141",
            "description": "betaxolol hydrochloride tablets 20mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12296",
            "description": "SECTRAL capsules 100mg [AVENTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12456",
            "description": "SOTAZIDE tablets [BRISTOL]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12495",
            "description": "BERKOLOL tablets 10mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12517",
            "description": "timolol maleate with bendroflumethiazide tablets 20mg + 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12519",
            "description": "KERLONE tablets 20mg [SANOFI S]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "12651",
            "description": "timolol maleate with bendroflumethiazide tablets 10mg + 2.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1288",
            "description": "TENORET tablets 50mg + 12.5mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1290",
            "description": "bisoprolol tablets 10mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1295",
            "description": "labetalol hydrochloride tablets 400mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "13051",
            "description": "sotalol tablets 200mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1333",
            "description": "oxprenolol tablets 40mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1334",
            "description": "oxprenolol modified release tablet 160mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "13394",
            "description": "TENORMIN syrup 25mg/5ml [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "13415",
            "description": "CORGARD tablets 40mg [SANOFI/AVE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "13487",
            "description": "BETA-CARDONE tablets 200mg [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "13499",
            "description": "LOPRESOR tablets 100mg [NOVARTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "13526",
            "description": "ATENIXCO tablets 100mg + 25mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "13871",
            "description": "co-prenozide (oxprenolol and cyclopenthiazide) modified release tablet 160mg + 0.25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14030",
            "description": "CARDICOR tablets 2.5mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14057",
            "description": "pindolol with clopamide tablets 10mg + 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14058",
            "description": "CARDICOR tablets 1.25mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14117",
            "description": "EUCARDIC tablets 3.125mg [ROCHE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14126",
            "description": "acebutolol hydrochloride and hydrochlorothiazide tablets 200mg + 12.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14146",
            "description": "EUCARDIC tablets 6.25mg [ROCHE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14438",
            "description": "CORGARETIC 80 tablets [SANOFI S]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1448",
            "description": "propranolol modified release capsules 160mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14502",
            "description": "metoprolol tartrate injection 5mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14552",
            "description": "PROPANIX tablets 10mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14673",
            "description": "pindolol tablets 15mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "14808",
            "description": "BEDRANOL modified release capsules 80mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "15042",
            "description": "TOLERZIDE tablets [BMS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "15117",
            "description": "nifedipine with atenolol capsules 20mg + 50mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "15176",
            "description": "TOTAMOL tablets 50mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "15488",
            "description": "metoprolol tartrate with chlortalidone tablets",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "15619",
            "description": "HALF-BETADUR CR capsules 80mg [MONMOUTH]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1572",
            "description": "sotalol tablets 80mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "15730",
            "description": "TOTAMOL tablets 100mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1597",
            "description": "labetalol hydrochloride tablets 100mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "16645",
            "description": "LABROCOL tablets 400mg [LAGAP]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "16776",
            "description": "CELECTOL tablets 400mg [PANTHEON]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "16786",
            "description": "chlortalidone with atenolol tablets 25mg+100mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1684",
            "description": "BETA-ADALAT capsules 50mg + 20mg [BAYER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "17082",
            "description": "SYPROL oral solution 5mg/5ml [ROSEMONT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "17149",
            "description": "MONOZIDE 10 tablets 10mg + 6.25mg [WYETH PHAR]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "17322",
            "description": "ATENIX tablets 25mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "17462",
            "description": "bisoprolol and hydrochlorothiazide tablets 10mg + 6.25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "17615",
            "description": "CARDICOR tablets 5mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "17679",
            "description": "sotalol injection 10mg/ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "17783",
            "description": "SPIROPROP tablets [PHARMACIA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "1788",
            "description": "atenolol with chlortalidone tablets 100mg+25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "18185",
            "description": "CARDICOR tablets 7.5mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "18287",
            "description": "CO-BETALOC SA tablets 200mg + 25mg [PHARMACIA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "18414",
            "description": "EUCARDIC tablets 12.5mg [ROCHE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "18743",
            "description": "TENBEN capsules 25mg + 1.25mg [GALEN]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "18950",
            "description": "TOTAMOL tablets 25mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19055",
            "description": "chlortalidone with atenolol tablets 12.5mg+50mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19068",
            "description": "labetalol hydrochloride injection 5mg/ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19142",
            "description": "bendroflumethiazide with timolol maleate tablets 2.5mg + 10mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19172",
            "description": "ATENOLOL tablets 25mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19178",
            "description": "BISOPROLOL tablets 10mg [RANBAXY]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19182",
            "description": "ATENOLOL tablets 50mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19191",
            "description": "ATENOLOL tablets 100mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19200",
            "description": "BISOPROLOL tablets 5mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19202",
            "description": "CARVEDILOL tablets 6.25mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19437",
            "description": "EUCARDIC tablets 25mg [ROCHE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "197",
            "description": "atenolol injection 5mg/10ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19853",
            "description": "CARDICOR tablets 3.75mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19858",
            "description": "CARDICOR tablets 10mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "19998",
            "description": "TRANDATE injection 100mg/20ml [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "20012",
            "description": "VISKEN tablets 15mg [SOVEREIGN]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "20082",
            "description": "LOPRESOR SR tablets 200mg [RECORDATI]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "20093",
            "description": "metoprolol tartrate with hydrochlorothiazide modified release tablet 200mg + 25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "20169",
            "description": "practolol injection 2mg/ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "20468",
            "description": "HALF BETA-PROGRANE sustained release capsules 80mg [TILLOMED]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "20502",
            "description": "ATENIX tablets 100mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "20728",
            "description": "ATENAMIN tablets 25mg [OPD]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21025",
            "description": "PRESTIM FORTE tablets [LEO]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21133",
            "description": "ATENAMIN tablets 50mg [OPD]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21182",
            "description": "hydrochlorothiazide with timolol and amiloride tablets 25mg + 10mg + 2.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21838",
            "description": "PROPANIX tablets 80mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21839",
            "description": "BERKOLOL tablets 80mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21866",
            "description": "BERKOLOL tablets 40mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21873",
            "description": "ATENIXCO tablets 50mg+12.5mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21885",
            "description": "OXYPRENIX SR tablets 160mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21905",
            "description": "BIPRANIX tablets 10mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "21966",
            "description": "BIPRANIX tablets 5mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "220",
            "description": "propranolol oral solution 5mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "22208",
            "description": "HALF PROPANIX LA sustained release capsules 80mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "22793",
            "description": "LABROCOL tablets 200mg [LAGAP]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "22912",
            "description": "bendroflumethiazide with propranolol capsules 2.5mg + 80mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "23131",
            "description": "bendroflumethiazide with propranolol modified release capsules 5mg + 160mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "23134",
            "description": "nadolol with bendroflumethiazide tablets 40mg + 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "23326",
            "description": "BETADUR CR sustained release capsules 160mg [MONMOUTH]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "23587",
            "description": "SLOPROLOL capsules 160mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2361",
            "description": "TRASICOR tablets 80mg [NOVARTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24",
            "description": "atenolol tablets 100mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24083",
            "description": "BISOPROLOL tablets 5mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24094",
            "description": "TRASICOR tablets 40mg [AMDIPHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2414",
            "description": "INDERAL tablets 10mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24191",
            "description": "ANTIPRESSAN tablets 50mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24195",
            "description": "ANTIPRESSAN tablets 100mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24218",
            "description": "BERKOLOL tablets 160mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24280",
            "description": "TOTARETIC tablets 100mg+25mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2432",
            "description": "TENORMIN LS tablets 50mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24461",
            "description": "BETALOC IV injection 5mg/5ml [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24635",
            "description": "SOTACOR injection 10mg/ml [BRISTOL]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "24832",
            "description": "LASIPRESSIN tablets [HOECHST]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2499",
            "description": "nadolol tablets 80mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "25359",
            "description": "RAPRANOL SR capsules 160mg [RANBAXY]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "25363",
            "description": "PRESTIM tablets [MEDA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "25367",
            "description": "RAPRANOL SR capsules 80mg [RANBAXY]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "25462",
            "description": "clopamide with pindolol tablets 5mg + 10mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "25644",
            "description": "APSOLOX tablets 80mg [APS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "25730",
            "description": "timolol maleate with amiloride and hydrochlorothiazide tablets",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2587",
            "description": "TENORMIN tablets 100mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2590",
            "description": "TENORMIN 25 tablets [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26",
            "description": "atenolol tablets 25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26211",
            "description": "ANTIPRESSAN tablets 25mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26228",
            "description": "PROPANIX LA modified release capsules 160mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26229",
            "description": "BETA-PROGRANE capsules 160mg [TILLOMED]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26248",
            "description": "TENCHLOR tablets 100mg + 25mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26255",
            "description": "LOPRANOL LA capsules 160mg [OPUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2629",
            "description": "carvedilol tablets 12.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26529",
            "description": "furosemide with penbutolol tablets",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26741",
            "description": "TOTARETIC tablets 50mg+12.5mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26895",
            "description": "SYPROL oral solution 10mg/5ml [ROSEMONT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "26922",
            "description": "BREVIBLOC injection 10mg/ml [BAXTER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "27357",
            "description": "OXPRENOLOL tablets 40mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "27486",
            "description": "propranolol injection 1mg/ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "27700",
            "description": "PROPRANOLOL tablets 40mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "27719",
            "description": "METOROS LS tablets 95mg [GEIGY]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "27727",
            "description": "sotalol injection 2mg/ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2775",
            "description": "labetalol hydrochloride tablets 200mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "2780",
            "description": "oxprenolol tablets 80mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "27946",
            "description": "nadolol with bendroflumethiazide tablets 80mg + 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "27964",
            "description": "APSOLOL tablets 40mg [APS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "28048",
            "description": "ANGILOL tablets 10mg [DDSA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "28128",
            "description": "PROPRANOLOL sustained release capsules 80mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "28177",
            "description": "hydrochlorothiazide with atenolol and amiloride capsules",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "28700",
            "description": "CARTROL tablets 10mg [NOVARTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "28788",
            "description": "HALF PROPATARD LA modified release capsules 80mg [GALEN]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "28996",
            "description": "BEDRANOL modified release capsules 160mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29180",
            "description": "TRASICOR tablets 80mg [AMDIPHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29230",
            "description": "SLOW-PREN tablets 160mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29368",
            "description": "ATENOLOL tablets 25mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29398",
            "description": "ATENAMIN tablets 100mg [OPD]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29427",
            "description": "hydrochlorothiazide with metoprolol tartrate tablets 12.5mg + 100mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29610",
            "description": "BETIM tablets 10mg [MEDA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "297",
            "description": "propranolol tablets 10mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29762",
            "description": "MEPRANIX tablets 50mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29763",
            "description": "PROPANIX tablets 160mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29827",
            "description": "carteolol hydrochloride tablets 10mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "29998",
            "description": "METOROS tablets 190mg [NOV/GEIGY]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3005",
            "description": "INDERAL LA capsules 160mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "30400",
            "description": "MEPRANIX tablets 100mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "30519",
            "description": "amiloride hydrochloride with timolol and hydrochlorothiazide tablets",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "30541",
            "description": "esmolol hydrochloride concentrate for solution for infusion 250mg/ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "30636",
            "description": "VASATEN tablets 50mg [SHIRE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "30770",
            "description": "LABETALOL tablets 200mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3087",
            "description": "propranolol oral solution 40mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "31214",
            "description": "PROPRANOLOL tablets 80mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "31470",
            "description": "TENCHLOR tablets 50mg+12.5mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "31536",
            "description": "ATENOLOL tablets 25mg [KENT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3167",
            "description": "propranolol tablets 160mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "31708",
            "description": "CO-TENIDONE tablets 50mg+12.5mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "31776",
            "description": "PROPRANOLOL tablets 40mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "31833",
            "description": "ANGILOL tablets 80mg [DDSA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "31934",
            "description": "ATENOLOL tablets 100mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32094",
            "description": "CO-TENIDONE tablets 50mg+12.5mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32114",
            "description": "BISOPROLOL tablets 5mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32135",
            "description": "BREVIBLOC concentrate for solution for infusion 250mg/ml [BAXTER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32162",
            "description": "PROPRANOLOL modified release capsules 80mg [LAGAP]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32552",
            "description": "CONGESCOR tablets 2.5mg [TILLOMED]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32630",
            "description": "VIVACOR tablets 10mg [LEXON]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32787",
            "description": "VISKEN tablets 15mg [AMDIPHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "32836",
            "description": "METOPROLOL tablets 50mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33079",
            "description": "ATENOLOL tablets 100mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33085",
            "description": "ATENOLOL tablets 100mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33092",
            "description": "ATENOLOL tablets 50mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33184",
            "description": "ATENOLOL tablets 100mg [WOCKHARDT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33374",
            "description": "CARVEDILOL tablets 12.5mg [GENUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33376",
            "description": "PROBETA LA capsules 160mg [TRINITY]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3344",
            "description": "BETALOC tablets 100mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33569",
            "description": "OXPRENOLOL SR tablets 160mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33578",
            "description": "SOTACOR injection 40mg/4ml [BMS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33602",
            "description": "SLO-PRO modified release capsules 160mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33644",
            "description": "PROPRANOLOL tablets 80mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33650",
            "description": "ATENOLOL tablets 50mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33657",
            "description": "ATENOLOL tablets 25mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33659",
            "description": "hydrochlorothiazide with metoprolol tartrate modified release tablet 25mg + 200mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33836",
            "description": "APSOLOL tablets 160mg [APS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33839",
            "description": "BISOPROLOL tablets 10mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33850",
            "description": "ATENOLOL tablets 50mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "33909",
            "description": "CONGESCOR tablets 1.25mg [TILLOMED]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34012",
            "description": "CO-TENIDONE tablets 100mg+25mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34034",
            "description": "CO-TENIDONE tablets 50mg+12.5mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34092",
            "description": "METOPROLOL tablets 100mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34094",
            "description": "METOPROLOL tablets 50mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34125",
            "description": "METOPROLOL tablets 100mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34171",
            "description": "LABETALOL tablets 100mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34177",
            "description": "LABETALOL tablets 100mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34185",
            "description": "PROPRANOLOL LA modified release capsules 80mg [APS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34188",
            "description": "LABETALOL tablets 200mg [CELLTECH]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34208",
            "description": "PROPRANOLOL SR capsules 160mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34214",
            "description": "PROPRANOLOL tablets 160mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34265",
            "description": "ATENOLOL tablets 50mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34365",
            "description": "ATENOLOL tablets 50mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34371",
            "description": "SOTALOL tablets 40mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34378",
            "description": "PROPRANOLOL tablets 10mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34407",
            "description": "METOPROLOL tablets 50mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34430",
            "description": "METOPROLOL tablets 50mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34443",
            "description": "ATENOLOL tablets 50mg [WOCKHARDT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34449",
            "description": "CO-TENIDONE tablets 50mg+12.5mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34492",
            "description": "ATENOLOL tablets 25mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34501",
            "description": "CARVEDILOL tablets 12.5mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34509",
            "description": "METOPROLOL tablets 100mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34520",
            "description": "SOTALOL tablets 80mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34575",
            "description": "ATENOLOL tablets 25mg [WOCKHARDT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34584",
            "description": "METOPROLOL tablets 50mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34585",
            "description": "ATENOLOL tablets 25mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34600",
            "description": "SOTALOL tablets 40mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34640",
            "description": "SOTALOL tablets 40mg [TILLOMED]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34690",
            "description": "SOTALOL tablets 80mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34695",
            "description": "ATENOLOL tablets 50mg [KENT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3474",
            "description": "BETALOC SA DURULE 200mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34740",
            "description": "CARVEDILOL tablets 6.25mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34741",
            "description": "CARVEDILOL tablets 3.125mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34754",
            "description": "ATENOLOL tablets 100mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34783",
            "description": "PROPRANOLOL tablets 10mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34804",
            "description": "PROPRANOLOL tablets 10mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34821",
            "description": "BISOPROLOL tablets 10mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34825",
            "description": "CO-TENIDONE tablets 50mg+12.5mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34854",
            "description": "METOPROLOL tablets 100mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34867",
            "description": "PROPRANOLOL capsules 80mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34868",
            "description": "PROPRANOLOL tablets 40mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34882",
            "description": "ATENOLOL tablets 50mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34884",
            "description": "PROPRANOLOL modified release capsules 160mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34890",
            "description": "METOPROLOL tablets 50mg [BERK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34899",
            "description": "CO-TENIDONE tablets 100mg+25mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34925",
            "description": "METOPROLOL tablets 50mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34945",
            "description": "PROPRANOLOL sustained release capsules 160mg [LAGAP]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34949",
            "description": "PROPRANOLOL sustained release capsules 160mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34963",
            "description": "BISOPROLOL tablets 5mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "34976",
            "description": "ATENOLOL tablets 25mg [TILLOMED]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "35054",
            "description": "CELECTOL tablets 200mg [WINTHROP]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "35062",
            "description": "TRASICOR tablets 20mg [AMDIPHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3516",
            "description": "oxprenolol tablets 20mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3526",
            "description": "amiloride hydrochloride with atenolol and hydrochlorothiazide capsules",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "35695",
            "description": "VISKEN tablets 5mg [AMDIPHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "35710",
            "description": "sotalol oral suspension 25mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "35778",
            "description": "LABROCOL tablets 100mg [LAGAP]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3588",
            "description": "MONOCOR tablets 5mg [WYETH PHAR]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "35938",
            "description": "PROPRANOLOL SR capsules 80mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "35940",
            "description": "CELECTOL tablets 400mg [WINTHROP]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "36261",
            "description": "ATENOLOL tablets 50mg [TILLOMED]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "36576",
            "description": "PROPRANOLOL tablets 10mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "36603",
            "description": "PROPRANOLOL SR capsules 160mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3691",
            "description": "sotalol with hydrochlorothiazide tablets 160mg + 25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "37118",
            "description": "BISOPROLOL tablets 2.5mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3748",
            "description": "oxprenolol tablets 160mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "37725",
            "description": "CO-TENIDONE tablets 100mg+25mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "37837",
            "description": "BISOPROLOL tablets 2.5mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "3827",
            "description": "PROPANIX tablets 40mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "38370",
            "description": "labetalol hydrochloride injection 100mg/20ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "38433",
            "description": "PROPRANOLOL oral solution 50mg/5ml [ROSEMONT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "38498",
            "description": "sotalol injection 40mg/4ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "38991",
            "description": "BISOPROLOL tablets 7.5mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "39233",
            "description": "PROPRANOLOL SR capsules 80mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "39423",
            "description": "SOTALOL tablets 80mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "39646",
            "description": "bisoprolol oral liquid 0.625mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "39819",
            "description": "esmolol hydrochloride solution for infusion 2500mg/250ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "39846",
            "description": "VIVACOR tablets 5mg [LEXON]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4004",
            "description": "SOTACOR tablets 80mg [BRISTOL]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "40167",
            "description": "METOPROLOL tablets 100mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "40240",
            "description": "LABETALOL tablets 400mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "40241",
            "description": "PROPRANOLOL LA capsules 160mg [APS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4025",
            "description": "SLOW TRASICOR sustained release tablets 160mg [AMDIPHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "40761",
            "description": "nebivolol tablets 2.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "41555",
            "description": "PROPRANOLOL tablets 40mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "41572",
            "description": "CO-TENIDONE tablets 100mg+25mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "41591",
            "description": "BISOPROLOL tablets 10mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "41740",
            "description": "CELIPROLOL tablets 200mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "41827",
            "description": "LABETALOL tablets 100mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "42152",
            "description": "SYPROL oral solution 50mg/5ml [ROSEMONT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4265",
            "description": "CELECTOL tablets 200mg [PANTHEON]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "42795",
            "description": "CELIPROLOL tablets 200mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "43251",
            "description": "BISOPROLOL tablets 1.25mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "43525",
            "description": "PROPRANOLOL tablets 10mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "43549",
            "description": "SOTALOL tablets 40mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "43564",
            "description": "BISOPROLOL tablets 5mg [PLIVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "44000",
            "description": "bisoprolol oral suspension 2.5mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "44083",
            "description": "LABETALOL tablets 200mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4410",
            "description": "carvedilol tablets 6.25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4429",
            "description": "TRASIDREX tablets [GOLDSHIELD]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "44808",
            "description": "NEBIVOLOL tablets 2.5mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "44858",
            "description": "ATENOLOL tablets 25mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45250",
            "description": "LABETALOL tablets 400mg [SANDOZ]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45289",
            "description": "metoprolol tartrate oral liquid",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45297",
            "description": "PROPRANOLOL tablets 40mg [IVAX]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45309",
            "description": "ACEBUTOLOL tablets 400mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45343",
            "description": "PROPRANOLOL SR capsules 80mg [CP PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4542",
            "description": "atenolol with nifedipine capsules 50mg + 20mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45494",
            "description": "PROPRANOLOL tablets 10mg [ALMUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45765",
            "description": "SYPROL oral solution 40mg/5ml [ROSEMONT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "45877",
            "description": "BETA-PROGRANE capsules 160mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4588",
            "description": "VISKEN tablets 5mg [SOVEREIGN]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4605",
            "description": "MODUCREN tablets [M S D]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46363",
            "description": "HALF BETA-PROGRANE sustained release capsules 80mg [TEVA]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46614",
            "description": "LOPRESOR tablets 50mg [RECORDATI]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46740",
            "description": "LOPRESOR tablets 100mg [RECORDATI]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46908",
            "description": "ATENOLOL tablets 100mg [KENT]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46931",
            "description": "ATENOLOL tablets 100mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46935",
            "description": "CARVEDILOL tablets 3.125mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46936",
            "description": "CARVEDILOL tablets 3.125mg [HILLCROSS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "46952",
            "description": "CO-TENIDONE tablets 100mg+25mg [ACTAVIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "47041",
            "description": "BISOPROLOL tablets 2.5mg [GEN (UK)]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "47107",
            "description": "carvedilol oral suspension 5mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "472",
            "description": "bisoprolol tablets 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4725",
            "description": "labetalol hydrochloride tablets 50mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "47300",
            "description": "NEBIVOLOL tablets 2.5mg [GLENMARK]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4771",
            "description": "EMCOR LS tablets 5mg [MERCK SER]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4796",
            "description": "INDERETIC capsules [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "4983",
            "description": "atenolol with amiloride and hydrochlorothiazide capsules",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5",
            "description": "atenolol tablets 50mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5284",
            "description": "pindolol tablets 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5330",
            "description": "CORGARETIC 40 tablets [SANOFI S]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5478",
            "description": "propranolol oral solution 10mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5713",
            "description": "bisoprolol tablets 7.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5721",
            "description": "co-tenidone (atenolol and chlortalidone) tablets 100mg+25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "581",
            "description": "atenolol with chlortalidone tablets 50mg+12.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5858",
            "description": "BETA-CARDONE tablets 40mg [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "594",
            "description": "bisoprolol tablets 2.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "5968",
            "description": "MONOCOR tablets 10mg [WYETH PHAR]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "599",
            "description": "bisoprolol tablets 1.25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "6066",
            "description": "atenolol sugar free oral solution 25mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "6751",
            "description": "BETA-CARDONE tablets 80mg [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7049",
            "description": "carvedilol tablets 25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7066",
            "description": "metoprolol tartrate with hydrochlorothiazide tablets 100mg + 12.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "707",
            "description": "propranolol tablets 40mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7091",
            "description": "bisoprolol tablets 3.75mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "739",
            "description": "metoprolol tartrate tablets 50mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7429",
            "description": "TENORMIN injection 5mg/10ml [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7474",
            "description": "TRASICOR tablets 20mg [NOVARTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "751",
            "description": "nebivolol tablets 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7528",
            "description": "NEBILET tablets 5mg [MENARINI]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "753",
            "description": "metoprolol tartrate tablets 100mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7543",
            "description": "KALTEN capsules [M&A PHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7553",
            "description": "bisoprolol oral suspension 5mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7620",
            "description": "acebutolol hydrochloride tablets 400mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "769",
            "description": "propranolol modified release capsules 80mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7852",
            "description": "BLOCADREN tablets 10mg [M S D]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7853",
            "description": "timolol maleate tablets 10mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "786",
            "description": "sotalol tablets 40mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "7974",
            "description": "celiprolol tablets 400mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8023",
            "description": "SECTRAL tablets 400mg [AVENTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8061",
            "description": "sotalol with hydrochlorothiazide tablets 80mg + 12.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8068",
            "description": "metoprolol tartrate modified release tablet 200mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8071",
            "description": "BETALOC tablets 50mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8113",
            "description": "acebutolol hydrochloride capsules 200mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8147",
            "description": "LOPRESORETIC tablets [NOV/GEIGY]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "817",
            "description": "carvedilol tablets 3.125mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8172",
            "description": "acebutolol hydrochloride capsules 100mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8189",
            "description": "SECADREX tablets [AVENTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "822",
            "description": "bisoprolol oral suspension 1.5mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8262",
            "description": "celiprolol tablets 200mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8290",
            "description": "TRASICOR tablets 40mg [NOVARTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8331",
            "description": "INDERAL tablets 160mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8369",
            "description": "INDEREX capsules [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8555",
            "description": "SECTRAL capsules 200mg [AVENTIS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8623",
            "description": "PRESTIM tablets [ICN]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8642",
            "description": "TENIF capsules 50mg + 20mg [ASTRAZENEC]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8673",
            "description": "oxprenolol with cyclopenthiazide modified release tablet 160mg+0.25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8707",
            "description": "TRANDATE tablets 200mg [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8807",
            "description": "TRANDATE tablets 400mg [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8935",
            "description": "nadolol tablets 40mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8978",
            "description": "PROPANIX sustained release capsules 160mg [ASHBOURNE]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "8987",
            "description": "propranolol with bendroflumethiazide modified release capsules 160mg + 5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "9016",
            "description": "TRANDATE tablets 100mg [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "9143",
            "description": "VISKALDIX tablets 10mg + 5mg [AMDIPHARM]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "9178",
            "description": "atenolol with bendroflumethiazide capsules 25mg + 1.25mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "9185",
            "description": "propranolol oral solution 80mg/5ml",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "9273",
            "description": "TRANDATE tablets 50mg [FOCUS]",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "9292",
            "description": "sotalol tablets 160mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "940",
            "description": "propranolol tablets 80mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          },
          {
            "code": "9783",
            "description": "co-tenidone (atenolol and chlortalidone) tablets 50mg+12.5mg",
            "attributes": {
              "Coding System (CPRD_product_code)": "CPRD_product_code",
              "Entity type": "res24: beta_blockers",
              "Category": "drug"
            }
          }
        ]
      }
    ],
    "status": 2,
    "doi": "https://doi.org/10.48533/mwp0-3d90",
    "is_deleted": null,
    "publish_status": 2,
    "owner": "ieuan.scanlon",
    "template": {
      "id": 1,
      "name": "Clinical-Coded Phenotype",
      "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.",
      "version_id": 1
    },
    "versions": [
      {
        "version_id": 1284,
        "version_name": "Beta Blockers",
        "version_date": "2021-10-06T16:28:13.583659Z",
        "is_published": true,
        "is_latest": true
      }
    ]
  }
]