[ { "phenotype_id": "PH647", "phenotype_version_id": 1294, "name": "Diuretics", "definition": "Objectives: \n\nTo conduct a fully independent, external validation of a research study based on one electronic health record database using a different database sampling from the same population.\n\n\nDesign: \n\nRetrospective cohort analysis of β-blocker therapy and all-cause mortality in patients with cancer.\n\n\nSetting: \n\nTwo UK national primary care databases (PCDs): the Clinical Practice Research Datalink (CPRD) and Doctors’ Independent Network (DIN).\n\n\nParticipants: \n\nCPRD data for 11 302 patients with cancer compared with published results from DIN for 3462 patients; study period January 1997 to December 2006.\n\n\nPrimary and secondary outcome measures:\n\nAll-cause mortality: overall; by treatment subgroup (β-blockers only, β-blockers plus other blood pressure lowering medicines (BPLM), other BPLMs only); and by cancer site.\n\n\nResults: \n\nUsing CPRD, β-blocker use was not associated with mortality (HR=1.03, 95% CI 0.93 to 1.14, vs patients prescribed other BPLMs only), but DIN β-blocker users had significantly higher mortality (HR=1.18, 95% CI 1.04 to 1.33). However, these HRs were not statistically different (p=0.063), but did differ for patients on β-blockers alone (CPRD=0.94, 95% CI 0.82 to 1.07; DIN=1.37, 95% CI 1.16 to 1.61; p<0.001). Results for individual cancer sites differed by study, but only significantly for prostate and pancreas cancers. Results were robust under sensitivity analyses, but we could not be certain that mortality was identically defined in both databases.\n\n\nConclusions: \n\nWe found a complex pattern of similarities and differences between databases. Overall treatment effect estimates were not statistically different, adding to a growing body of evidence that different UK PCDs produce comparable effect estimates. However, individually the two studies lead to different conclusions regarding the safety of β-blockers and some subgroup effects differed significantly. Single studies using even internally wellvalidated databases do not guarantee generalisable results, especially for subgroups, and confirmatory studies using at least one other independent data source are strongly recommended.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "David A Springate, Darrent M Aschroft, Evangelos Kontopantelis, Tim Doran, Ronan Ryan, David Reeves, Can analyses of electronic patient records be independently and externally validated? Study 2—the effect of β-adrenoceptor blocker therapy on cancer survival a retrospective cohort study. BMJ Open, 5(e007299), 2014." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:28:28.920088Z", "author": "David A Springate, Darren M Aschroft, Evangelos Kontopantelis, Tim Doran, Ronan Ryan, David Reeves", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:28:28.920116Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Drug", "value": "3" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 }, { "name": "Doctors Independent Network", "value": 28, "uid": "", "url": "", "datasource_id": 28 } ], "coding_system": [ { "name": "GPRD product codes", "value": 14 } ], "event_date_range": "01/01/19997 - 31/12/2006", "concept_information": [ { "concept_id": 2067, "concept_version_id": 5272, "concept_name": "Diuretics - Primary Care", "coding_system": { "id": 14, "name": "GPRD product codes", "description": "GPRD product codes" }, "phenotype_id": "PH647", "phenotype_version_id": 1294, "phenotype_name": "Diuretics", "code_attribute_header": [ "Coding System (CPRD_product_code)", "Entity type", "Category" ], "codes": [ { "code": "1021", "description": "INNOZIDE tablets [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "10316", "description": "COAPROVEL tablets 150mg + 12.5mg [SANOFI BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "10323", "description": "losartan with hydrochlorothiazide tablets 100mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "10627", "description": "CO-BETALOC tablets 100mg + 12.5mg [PHARMACIA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "10902", "description": "captopril with hydrochlorothiazide tablets 50mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11133", "description": "hydrochlorothiazide with captopril tablets 25mg + 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1124", "description": "TENORETIC tablets 100mg + 25mg [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1125", "description": "NAVIDREX -K tablets [NOV/CIBA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11338", "description": "bendroflumethiazide with nadolol tablets 5mg + 40mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11351", "description": "co-zidocapt (hydrochlorothiazide and captopril) tablets 25mg + 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11384", "description": "co-flumactone (hydroflumethiazide and spironolactone) tablets 50mg+50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11448", "description": "irbesartan with hydrochlorothiazide tablets 150mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11469", "description": "irbesartan with hydrochlorothiazide tablets 300mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11526", "description": "COAPROVEL tablets 300mg + 12.5mg [SANOFI BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11561", "description": "co-zidocapt (hydrochlorothiazide and captopril) tablets 12.5mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11641", "description": "captopril with hydrochlorothiazide tablets 25mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1170", "description": "cyclopenthiazide tablets 0.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "11864", "description": "valsartan with hydrochlorothiazide tablets 160mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12054", "description": "propranolol with bendroflumethiazide capsules 80mg + 2.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1209", "description": "NEO-NACLEX tablets 5mg [GOLDSHIELD]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12110", "description": "hydroflumethiazide tablets 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12360", "description": "NEPHRIL tablets 1mg [PFIZER]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12440", "description": "HYDROSALURIC tablets 25mg [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1251", "description": "MODURET 25 tablets [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12517", "description": "timolol maleate with bendroflumethiazide tablets 20mg + 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12546", "description": "KALSPARE tablets [DOMINION]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12547", "description": "triamterene with chlortalidone tablets 50mg + 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12651", "description": "timolol maleate with bendroflumethiazide tablets 10mg + 2.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1288", "description": "TENORET tablets 50mg + 12.5mg [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "12926", "description": "polythiazide tablets 1mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1297", "description": "ALDACTIDE film coated tablets 50mg + 50mg [PHARMACIA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "13246", "description": "chlorothiazide oral suspension 150mg/5ml", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "13363", "description": "ESIDREX tablets 50mg [NOV/CIBA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "13525", "description": "HYDRENOX tablets 50mg [KNOLL]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "13526", "description": "ATENIXCO tablets 100mg + 25mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "13871", "description": "co-prenozide (oxprenolol and cyclopenthiazide) modified release tablet 160mg + 0.25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "14126", "description": "acebutolol hydrochloride and hydrochlorothiazide tablets 200mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "14228", "description": "COVERSYL PLUS tablets [SERVIER]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "14283", "description": "valsartan with hydrochlorothiazide tablets 160mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "14438", "description": "CORGARETIC 80 tablets [SANOFI S]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "14738", "description": "hydrochlorothiazide with losartan tablets 12.5mg + 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "14870", "description": "telmisartan with hydrochlorothiazide tablets 40mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "15031", "description": "ACCURETIC tablets 10mg + 12.5mg [PFIZER]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "15108", "description": "quinapril and hydrochlorothiazide tablets 10mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "15127", "description": "hydrochlorothiazide with triamterene tablets 25mg+50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "15135", "description": "hydrochlorothiazide with captopril tablets 12.5mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1520", "description": "CAPOZIDE tablets [SQUIBB]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "15457", "description": "BAYCARON tablets 25mg [BAYER]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "15488", "description": "metoprolol tartrate with chlortalidone tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "15811", "description": "co-flumactone (hydroflumethiazide and spironolactone) tablets 25mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "16060", "description": "valsartan with hydrochlorothiazide tablets 80mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "16161", "description": "telmisartan with hydrochlorothiazide tablets 80mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "16498", "description": "KALSPARE tablets [DHP]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "16632", "description": "HYDROSALURIC tablets 50mg [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "16786", "description": "chlortalidone with atenolol tablets 25mg+100mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "17143", "description": "mefruside tablets 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1721", "description": "DYAZIDE tablets [GOLDSHIELD]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "17252", "description": "ESIDREX tablets 25mg [NOV/CIBA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "17655", "description": "CARACE 10 plus tablets [BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "17689", "description": "MICARDIS PLUS tablets 80mg + 12.5mg [BOEH INGL]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "17720", "description": "SALURIC tablets 500mg [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "1788", "description": "atenolol with chlortalidone tablets 100mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18200", "description": "olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18202", "description": "MICARDIS PLUS tablets 40mg + 12.5mg [BOEH INGL]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18263", "description": "ACEZIDE tablets [SQUIBB]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18267", "description": "ENDURON tablets 5mg [ABBOTT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18287", "description": "CO-BETALOC SA tablets 200mg + 25mg [PHARMACIA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18361", "description": "AMILMAXCO tablets [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18606", "description": "diltiazem and hydrochlorothiazide modified release capsules 150mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18726", "description": "TRIAMAXCO tablets [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18733", "description": "co-amilozide (amiloride and hydrochlorothiazide) oral solution 5mg + 50mg/5ml", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18743", "description": "TENBEN capsules 25mg + 1.25mg [GALEN]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18903", "description": "olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "18973", "description": "CENTYL tablets 2.5mg [BURGESS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "19055", "description": "chlortalidone with atenolol tablets 12.5mg+50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "19142", "description": "bendroflumethiazide with timolol maleate tablets 2.5mg + 10mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "19352", "description": "XURET low dose tablets 0.5mg [GALEN]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "19890", "description": "hydrochlorothiazide with amiloride tablets 25mg+2.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2", "description": "bendroflumethiazide tablets 2.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2001", "description": "ALDACTIDE film coated tablets 25mg + 25mg [PHARMACIA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2002", "description": "amiloride hydrochloride with hydrochlorothiazide tablets 5mg + 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "20057", "description": "methyclothiazide tablets 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "20066", "description": "AMIL-CO tablets 5mg + 50mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "20093", "description": "metoprolol tartrate with hydrochlorothiazide modified release tablet 200mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2046", "description": "NAVIDREX tablets 0.5mg [GOLDSHIELD]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "21025", "description": "PRESTIM FORTE tablets [LEO]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "21182", "description": "hydrochlorothiazide with timolol and amiloride tablets 25mg + 10mg + 2.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "21231", "description": "CARALPHA tablets 20mg + 12.5mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "21423", "description": "COZAAR-COMP tablets 100mg + 25mg [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "21803", "description": "BERKOZIDE tablets 2.5mg [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "21867", "description": "BERKOZIDE tablets 5mg [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "21873", "description": "ATENIXCO tablets 50mg+12.5mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2255", "description": "NAVISPARE tablets [GOLDSHIELD]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "22912", "description": "bendroflumethiazide with propranolol capsules 2.5mg + 80mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "22923", "description": "hydrochlorothiazide with amiloride tablets 50mg + 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "23131", "description": "bendroflumethiazide with propranolol modified release capsules 5mg + 160mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "23134", "description": "nadolol with bendroflumethiazide tablets 40mg + 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "23427", "description": "BENDROFLUMETHIAZIDE tablets 5mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "23456", "description": "hydrochlorothiazide with valsartan tablets 25mg + 160mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "23505", "description": "ADIZEM XL PLUS controlled release capsules 150mg + 12.5mg [NAPP]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "24008", "description": "VASETIC tablets [SHIRE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "24189", "description": "NEO-BENDROMAX tablets 2.5mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "24190", "description": "NEO-BENDROMAX tablets 5mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "24268", "description": "hydrochlorothiazide with valsartan tablets 12.5mg + 80mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "24280", "description": "TOTARETIC tablets 100mg+25mg [CP PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "24484", "description": "hydrochlorothiazide with valsartan tablets 12.5mg + 160mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "24632", "description": "hydrochlorothiazide with losartan tablets 25mg + 100mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "25363", "description": "PRESTIM tablets [MEDA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "25382", "description": "CO-DIOVAN tablets 160mg + 25mg [NOVARTIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "25500", "description": "HYPERTANE 50 tablets [SCHWARZ]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "25505", "description": "SPIRO-CO tablets 50mg+50mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "25730", "description": "timolol maleate with amiloride and hydrochlorothiazide tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2612", "description": "indapamide tablets 2.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "26219", "description": "ZIDA-CO tablets 5mg + 50mg [OPUS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "26220", "description": "DELVAS tablets [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "26248", "description": "TENCHLOR tablets 100mg + 25mg [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "26256", "description": "OPUMIDE tablets 2.5mg [OPUS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "26275", "description": "NINDAXA tablets 2.5mg [ASHBOURNE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "26741", "description": "TOTARETIC tablets 50mg+12.5mg [CP PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "27256", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [WOCKHARDT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "27520", "description": "OLMETEC PLUS tablets 20mg + 25mg [DAIIC-SANK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "27689", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "27946", "description": "nadolol with bendroflumethiazide tablets 80mg + 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "27957", "description": "NATRAMID tablets 2.5mg [TRINITY]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "28157", "description": "KALSPARE LS tablets [DOMINION]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "28177", "description": "hydrochlorothiazide with atenolol and amiloride capsules", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2833", "description": "cyclopenthiazide -k tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "29427", "description": "hydrochlorothiazide with metoprolol tartrate tablets 12.5mg + 100mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "29529", "description": "hydroflumethiazide with spironolactone tablets 25mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "29634", "description": "OLMETEC PLUS tablets 20mg + 12.5mg [DAIIC-SANK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "2982", "description": "ZESTORETIC 20-tablets 20mg + 12.5mg [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "29991", "description": "CENTYL tablets 5mg [BURGESS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "30272", "description": "benzthiazide with triamterene capsules", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "30519", "description": "amiloride hydrochloride with timolol and hydrochlorothiazide tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3054", "description": "HYGROTON tablets 100mg [ALLIANCE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3056", "description": "NATRILIX SR sustained release tablets 1.5mg [SERVIER]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "31131", "description": "SPIRO-CO tablets 25mg+25mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "31150", "description": "CO-AMILOZIDE tablets 5mg+50mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "31470", "description": "TENCHLOR tablets 50mg+12.5mg [BERK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "31670", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "31708", "description": "CO-TENIDONE tablets 50mg+12.5mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "31820", "description": "BENDROFLUMETHIAZIDE tablets 5mg [WOCKHARDT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3203", "description": "CAPOZIDE LS tablets [SQUIBB]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "32094", "description": "CO-TENIDONE tablets 50mg+12.5mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "32166", "description": "CAPTO-CO tablets 25mg+50mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3293", "description": "MODURETIC solution [BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "33083", "description": "INDAPAMIDE tablets 2.5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "33353", "description": "LISINOPRIL AND HYDROCHLOROTHIAZIDE tablets 20mg + 12.5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "33415", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "33651", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "33659", "description": "hydrochlorothiazide with metoprolol tartrate modified release tablet 25mg + 200mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "33724", "description": "DIURIL oral suspension 250mg/5ml [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34012", "description": "CO-TENIDONE tablets 100mg+25mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34034", "description": "CO-TENIDONE tablets 50mg+12.5mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34059", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34124", "description": "BENDROFLUMETHIAZIDE tablets 5mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34367", "description": "CO-AMILOZIDE tablets 2.5mg+25mg [WOCKHARDT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34449", "description": "CO-TENIDONE tablets 50mg+12.5mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34551", "description": "INDAPAMIDE tablets 2.5mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34602", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [SOVEREIGN]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "348", "description": "MODURETIC tablets [BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34803", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [REGENT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34825", "description": "CO-TENIDONE tablets 50mg+12.5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "34899", "description": "CO-TENIDONE tablets 100mg+25mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3517", "description": "hydrochlorothiazide tablets 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "35196", "description": "COAPROVEL tablets 300mg + 25mg [SANOFI BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3526", "description": "amiloride hydrochloride with atenolol and hydrochlorothiazide capsules", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "35380", "description": "hydrochlorothiazide with olmesartan medoxomil tablets 12.5mg + 20mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3548", "description": "chlortalidone tablets 100mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "35481", "description": "irbesartan with hydrochlorothiazide tablets 300mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3701", "description": "amiloride hydrochloride with hydrochlorothiazide tablets 2.5mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "37294", "description": "triamterene with chlortalidone tablets 50mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "37650", "description": "losartan with hydrochlorothiazide tablets 100mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "37710", "description": "LISINOPRIL AND HYDROCHLOROTHIAZIDE tablets 10mg + 12.5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "37725", "description": "CO-TENIDONE tablets 100mg+25mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "37747", "description": "COZAAR-COMP tablets 100mg + 12.5mg [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "37908", "description": "COVERSYL ARGININE PLUS tablets 5mg + 1.25mg [SERVIER]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "37978", "description": "perindopril arginine with indapamide tablets 5mg + 1.25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "38367", "description": "hydrochlorothiazide with losartan tablets 12.5mg + 100mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "38459", "description": "telmisartan with hydrochlorothiazide tablets 80mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "38889", "description": "MICARDIS PLUS tablets 80mg + 25mg [BOEH INGL]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "38995", "description": "ZESTORETIC 20 tablets [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "39021", "description": "hydrochlorothiazide with olmesartan medoxomil tablets 25mg + 20mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "39137", "description": "ZESTORETIC 10 tablets [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "39147", "description": "CARACE 20 PLUS tablets [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "39227", "description": "CAPOZIDE LS tablets [BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "39242", "description": "CARACE 10 PLUS tablets [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "39447", "description": "VARBIM XL prolonged release tablet 1.5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "3997", "description": "HYGROTON tablets 50mg [ALLIANCE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "40149", "description": "BENDROFLUMETHIAZIDE tablets 5mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4034", "description": "amiloride hydrochloride with hydrochlorothiazide solution 5mg + 50mg/5ml", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4044", "description": "DIUREXAN tablets 20mg [MEDA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "40886", "description": "BENDROFLUMETHIAZIDE tablets 2.5mg [ALMUS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "40907", "description": "INDAPAMIDE tablets 2.5mg [GENUS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "41517", "description": "BENDROFLUMETHIAZIDE tablets 5mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "41556", "description": "CO-AMILOZIDE tablets 5mg+50mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "41572", "description": "CO-TENIDONE tablets 100mg+25mg [TEVA]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "41861", "description": "TENSAID XL tablets 1.5mg [GEN (UK)]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "41885", "description": "ETHIBIDE XL prolonged release tablet 1.5mg [GENUS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "42142", "description": "MODURETIC tablets [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "42906", "description": "INDAPAMIDE tablets 2.5mg [NICHE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "43184", "description": "MAPEMID XL prolonged release tablet 1.5mg [RATIOPHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4332", "description": "metolazone tablets 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "43322", "description": "olmesartan medoxomil with hydrochlorothiazide tablets 40mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4334", "description": "metolazone low dose tablets 500micrograms", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "43516", "description": "INDAPAMIDE tablets 2.5mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "43915", "description": "OLMETEC PLUS tablets 40mg + 12.5mg [DAIIC-SANK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "44168", "description": "INDIPAM XL prolonged release tablet 1.5mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4429", "description": "TRASIDREX tablets [GOLDSHIELD]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4540", "description": "COZAAR-COMP tablets 50mg + 12.5mg [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "45916", "description": "hydroflumethiazide with spironolactone tablets 50mg+50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4605", "description": "MODUCREN tablets [M S D]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46302", "description": "NEO-NACLEX tablets 2.5mg [GOLDSHIELD]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46355", "description": "SEVIKAR HCT tablets 20mg + 5mg + 12.5mg [DAIIC-SANK]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46675", "description": "INDAPAMIDE SR tablets 1.5mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46687", "description": "olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 20mg + 5mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46715", "description": "olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 10mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46792", "description": "olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 5mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46916", "description": "CO-AMILOZIDE tablets 5mg+50mg [HILLCROSS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "46952", "description": "CO-TENIDONE tablets 100mg+25mg [ACTAVIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "47467", "description": "olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 5mg + 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4796", "description": "INDERETIC capsules [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "4983", "description": "atenolol with amiloride and hydrochlorothiazide capsules", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "5112", "description": "indapamide modified release tablet 1.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "5189", "description": "enalapril with hydrochlorothiazide tablets 20mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "5330", "description": "CORGARETIC 40 tablets [SANOFI S]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "5416", "description": "co-triamterzide (triamterene and hydrochlorothiazide) tablets 50mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "542", "description": "hydrochlorothiazide tablets 25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "5721", "description": "co-tenidone (atenolol and chlortalidone) tablets 100mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "5727", "description": "cyclopenthiazide with amiloride tablets 250micrograms + 2.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "58", "description": "bendroflumethiazide tablets 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "581", "description": "atenolol with chlortalidone tablets 50mg+12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "605", "description": "chlortalidone tablets 50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "6359", "description": "ZESTORETIC 10-tablets 10mg + 12.5mg [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "6437", "description": "losartan with hydrochlorothiazide tablets 50mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "6468", "description": "lisinopril with hydrochlorothiazide tablets 20mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "6786", "description": "lisinopril with hydrochlorothiazide tablets 10mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "6794", "description": "perindopril erbumine with indapamide tablets 4mg + 1.25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "6816", "description": "chlorothiazide oral suspension 250mg/5ml", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "6877", "description": "CO-DIOVAN tablets 160mg + 12.5mg [NOVARTIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7066", "description": "metoprolol tartrate with hydrochlorothiazide tablets 100mg + 12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7136", "description": "DYTIDE capsules 50mg+25mg [GOLDSHIELD]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7351", "description": "bendroflumethiazide oral suspension 2.5mg/5ml", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7543", "description": "KALTEN capsules [M&A PHARM]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7618", "description": "xipamide tablets 20mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "764", "description": "CO-DIOVAN tablets 80mg + 12.5mg [NOVARTIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7641", "description": "NATRILIX tablets 2.5mg [SERVIER]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7698", "description": "APRINOX tablets 5mg [SOVEREIGN]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7740", "description": "triamterene with benzthiazide capsules 50mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "7961", "description": "spironolactone with hydroflumethiazide tablets 50mg+50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8058", "description": "NORMETIC tablets [ABBOTT]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8147", "description": "LOPRESORETIC tablets [NOV/GEIGY]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8189", "description": "SECADREX tablets [AVENTIS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8303", "description": "TENAVOID tablets [BURGESS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8369", "description": "INDEREX capsules [ASTRAZENEC]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8464", "description": "meprobamate with bendroflumethiazide tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8521", "description": "spironolactone with hydroflumethiazide tablets 25mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8526", "description": "APRINOX tablets 2.5mg [SOVEREIGN]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8602", "description": "METENIX tablets 5mg [SANOFI/AVE]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8623", "description": "PRESTIM tablets [ICN]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8673", "description": "oxprenolol with cyclopenthiazide modified release tablet 160mg+0.25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8836", "description": "chlorothiazide tablets 500mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8891", "description": "HYGROTON -K tablets [NOV/GEIGY]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8897", "description": "TRIAM-CO tablets 50mg+25mg [IVAX]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "8987", "description": "propranolol with bendroflumethiazide modified release capsules 160mg + 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "9178", "description": "atenolol with bendroflumethiazide capsules 25mg + 1.25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "9223", "description": "triamterene with hydrochlorothiazide tablets 50mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "923", "description": "co-amilozide (amiloride and hydrochlorothiazide) tablets 5mg+50mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "924", "description": "co-amilozide (amiloride and hydrochlorothiazide) tablets 2.5mg+25mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "9764", "description": "CARACE 20 plus tablets [BMS]", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } }, { "code": "9783", "description": "co-tenidone (atenolol and chlortalidone) tablets 50mg+12.5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res24: diuretics", "Category": "drug" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/at5x-pv53", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1294, "version_name": "Diuretics", "version_date": "2021-10-06T16:28:28.952835Z", "is_published": true, "is_latest": true } ] } ]