[ { "phenotype_id": "PH679", "phenotype_version_id": 1358, "name": "HRT Oestrogens (P19)", "definition": "Study question:\n\nWhat is the prevalence of different types of potentially hazardous prescribing in general practice in the United Kingdom, and what is the variation between practices?\n\n\nMethods:\n\nA cross sectional study included all adult patients potentially at risk of a prescribing or monitoring error defined by a combination of diagnoses and prescriptions in 526 general practices contributing to the Clinical Practice Research Datalink (CPRD) up to 1 April 2013. Primary outcomes were the prevalence of potentially hazardous prescriptions of anticoagulants, anti-platelets, NSAIDs, β blockers, glitazones, metformin, digoxin, antipsychotics, combined hormonal contraceptives, and oestrogens and monitoring by blood test less frequently than recommended for patients with repeated prescriptions of angiotensin converting enzyme inhibitors and loop diuretics, amiodarone, methotrexate, lithium, or warfarin.\n\n\nStudy answer and limitations:\n\n49 927 of 949 552 patients at risk triggered at least one prescribing indicator (5.26%, 95% confidence interval 5.21% to 5.30%) and 21 501 of 182 721 (11.8%, 11.6% to 11.9%) triggered at least one monitoring indicator. The prevalence of different types of potentially hazardous prescribing ranged from almost zero to 10.2%, and for inadequate monitoring ranged from 10.4% to 41.9%. Older patients and those prescribed multiple repeat medications had significantly higher risks of triggering a prescribing indicator whereas younger patients with fewer repeat prescriptions had significantly higher risk of triggering a monitoring indicator. There was high variation between practices for some indicators. Though prescribing safety indicators describe prescribing patterns that can increase the risk of harm to the patient and should generally be avoided, there will always be exceptions where the indicator is clinically justified. Furthermore there is the possibility that some information is not captured by CPRD for some practices—for example, INR results in patients receiving warfarin.\n\n\nWhat this study adds:\n\nThe high prevalence for certain indicators emphasises existing prescribing risks and the need for their appropriate consideration within primary care, particularly for older patients and those taking multiple medications. The high variation between practices indicates potential for improvement through targeted practice level intervention.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Ashcroft, Examining variations in prescribing safety in UK general practice cross sectional study using the Clinical Practice Research Datalink. BMJ, 351(h5501), 2015." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:29:50.652835Z", "author": "S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Aschroft", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:29:50.652863Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Drug", "value": "3" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "GPRD product codes", "value": 14 } ], "event_date_range": "Start - 01/02/2013", "concept_information": [ { "concept_id": 2099, "concept_version_id": 5336, "concept_name": "HRT Oestrogens (P19) - Primary Care", "coding_system": { "id": 14, "name": "GPRD product codes", "description": "GPRD product codes" }, "phenotype_id": "PH679", "phenotype_version_id": 1358, "phenotype_name": "HRT Oestrogens (P19)", "code_attribute_header": [ "Coding System (CPRD_product_code)", "Entity type", "Category" ], "codes": [ { "code": "10052", "description": "Progynova TS 50micrograms/24hours transdermal patches (Bayer Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "10076", "description": "Estradot 75micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "10096", "description": "Estradot 100micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "10126", "description": "Estradot 25micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "10180", "description": "Estradot 50micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "10946", "description": "Menorest 50 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "10967", "description": "Menorest 37.5 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11157", "description": "Estradiol and (estradiol with dydrogesterone) 1mg with (1mg with 10mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11297", "description": "Estradiol valerate and (estradiol valerate with levonorgestrel) 2mg with (2mg with 75micrograms) tab", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11363", "description": "Estradiol and (estradiol with dydrogesterone) 2mg with (2mg with 20mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11375", "description": "Estradiol 50micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11430", "description": "Estradiol 25micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11511", "description": "Estradiol and (estradiol with dydrogesterone) 2mg with (2mg with 10 mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1160", "description": "Prempak-C 0.625mg/0.15mg tablets (Pfizer Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1161", "description": "Prempak-C 1.25mg/0.15mg tablets (Pfizer Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11642", "description": "Estradiol valerate and (estradiol valerate with levonorgestrel) 1mg with (1mg with 250micrograms) ta", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11672", "description": "Estradiol 25micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1183", "description": "Estracombi TTS patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "11882", "description": "Estradiol 50micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12661", "description": "Estradiol valerate with medroxyprogesterone acetate tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1268", "description": "Kliofem tablets (Novo Nordisk Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12713", "description": "Estradiol valerate and (estradiol valerate with norethisterone) 2mg with (2mg with 1 mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12773", "description": "Estradiol 100micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12788", "description": "Estradiol 1mg / Norethisterone acetate 500microgram tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12807", "description": "Estradiol with norethisterone acetate ( continuous combined) 2mg with 0.7mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12907", "description": "Estradiol and (estradiol with dydrogesterone) tablets 1mg with 5mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12953", "description": "Estradiol 1mg / Dydrogesterone 5mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "12970", "description": "Conjugated oestrogens 1.25mg tablets and Norgestrel 150microgram tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "13146", "description": "Novofem tablets (Novo Nordisk Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1331", "description": "Premarin 0.625mg tablets (Pfizer Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "13582", "description": "Menorest 75 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "13945", "description": "Estradiol and (estradiol with levonorgestrel) 80mcg/24hrs with (50mcg+20mcg/24hr) twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14027", "description": "Estradiol with (estradiol with norethisterone acetate) 1mg with (1mg with 1mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14234", "description": "Estradiol 37.5micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14569", "description": "Estradiol and (estradiol with norethisterone) and (estradiol) 2mg with (2mg with 1mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14580", "description": "Dermestril 25 patches (ProStrakan Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14596", "description": "Estradiol and (estradiol with norethisterone) and (estradiol) triphasic forte 4mg with (4mg with 1mg", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14792", "description": "Estradiol 50micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14812", "description": "Estradiol with (estradiol with norethisterone acetate) 50mcg/24 hr with (50mcg+170mcg/24 hr) twice w", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1488", "description": "Evorel -50 50microgram/24hr (3.2mg/unit) Transdermal patch (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1489", "description": "Evorel -75 75microgram/24 hr(4.8mg/unit) Transdermal patch (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "14950", "description": "Estradiol 50micrograms/24hours / Norethisterone 170micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "15100", "description": "Estradiol 37.5micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "15194", "description": "Dermestril 100 patches (ProStrakan Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "15298", "description": "Estradiol 25micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "15328", "description": "Estradiol 25micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1568", "description": "Tridestra tablets (Orion Pharma (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "15869", "description": "Dermestril 50 patches (ProStrakan Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "15880", "description": "Dermestril - Septem 75 patches (ProStrakan Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "16367", "description": "Estradiol valerate 1mg / Medroxyprogesterone 2.5mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "16392", "description": "Estradiol valerate 2mg / Medroxyprogesterone 5mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "16437", "description": "Estradiol 100micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "16443", "description": "FemTab Continuous tablets (Merck Serono Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "16493", "description": "Angeliq tablets (Bayer Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "16997", "description": "Estradiol with (estradiol with norethisterone acetate) 2mg with (2mg with 1 mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "17529", "description": "Estradiol 2mg vaginal ring", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1760", "description": "Prempak 0.625 Tablet (Wyeth Pharmaceuticals)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1797", "description": "Oestrogel 0.06% Gel (Aventis Pharma)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18009", "description": "Estradiol 50micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18167", "description": "Estradiol valerate and (estradiol valerate with medroxyprogesterone acetate) with placebo 2mg with (", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18218", "description": "Estradiol 100micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18311", "description": "Estriol 250micrograms tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18383", "description": "Estradiol 80micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18437", "description": "Estradiol 75micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18502", "description": "Estradiol 75micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18530", "description": "Estradiol valerate and (estradiol valerate with norgestrel) 2mg with (2mg with 500micrograms) tablet", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18600", "description": "Estradiol 75micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1873", "description": "Climaval 1mg tablets (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "18901", "description": "Estradiol 50micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "19135", "description": "Estradiol 50mg implant (Merck Sharp & Dohme Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "19145", "description": "Estradiol 50micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "1922", "description": "Hormonin Tablet (Shire Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "19429", "description": "Conjugat oestrogen equi and (conjugat oestrogen equi with medroxyprogesterone acetate 625 micrograms", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "19432", "description": "Estradiol valerate 1mg / Medroxyprogesterone 5mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "19487", "description": "Estradot 37.5micrograms/24hours patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "19974", "description": "Estradiol 50micrograms/24hours / Levonorgestrel 7micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "19986", "description": "Estradiol and (estradiol with levonorgestrel) 50mcg/24hrs with (50mcg+10mcg/24hrs) once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "20135", "description": "Estradiol 75micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "20155", "description": "Estradiol 50micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "20393", "description": "Mixogen Tablet (Organon Laboratories Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "206", "description": "Estraderm TTS 100 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "20888", "description": "Adgyn Estro 2mg tablets (ProStrakan Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "20895", "description": "Dermestril - Septem 50 patches (ProStrakan Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2111", "description": "Climagest 2mg tablets (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2115", "description": "Kliovance tablets (Novo Nordisk Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2140", "description": "FemSeven 50 patches (Teva UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2141", "description": "Evorel -25 25microgram/24hr (1.6mg/unit) Transdermal patch (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2208", "description": "Trisequens tablets (Novo Nordisk Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2209", "description": "Livial 2.5mg tablets (Merck Sharp & Dohme Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "22335", "description": "Estradiol 100micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "22372", "description": "Estradiol 80micrograms/24hours transdermal patches and Dydrogesterone 10mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2262", "description": "Climaval 2mg tablets (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "22741", "description": "Conjugated oestrogens 625microgram tablets and Norgestrel 150microgram tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "22975", "description": "Estradiol 1mg / Drospirenone 2mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "23152", "description": "Estradiol 40micrograms/24hours transdermal patches and Dydrogesterone 10mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2397", "description": "Evorel -100 100microgram/24 hr (6.4mg/unit) Transdermal patch (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2402", "description": "Vagifem 25microgram vaginal tablets (Novo Nordisk Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2457", "description": "Estradiol valerate 1mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "24917", "description": "Estradiol valerate 2mg / Norethisterone 700microgram tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "256", "description": "Tibolone 2.5mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2597", "description": "Premarin 0.625mg/g vaginal cream (Pfizer Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "26049", "description": "Estradiol 100micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2729", "description": "Evorel Conti patches (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2766", "description": "Climesse tablets (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "28230", "description": "Clinorette tablets (ReSource Medical UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "29449", "description": "Estradiol 1mg/ml injection", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "29573", "description": "Dienestrol 5mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "2977", "description": "Estradiol 50mg implant", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3002", "description": "Elleste Duet 1mg tablets (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3036", "description": "Cyclo-Progynova 2mg tablets (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3040", "description": "Estraderm MX 50 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3131", "description": "Femapak 40 (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "31330", "description": "Estradio; 5m/ml injection", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3179", "description": "Progynova 1mg tablets (Bayer Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "32930", "description": "Dermestril septem 25microgram/24hr Transdermal patch (Strakan Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3387", "description": "Estraderm MX 25 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "34174", "description": "Conjugated oestrogens equine with medroxyprogesterone acetate 625micrograms with 10mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3423", "description": "Conjugated oestrogens 625microgram tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3433", "description": "Sandrena 0.10% Gel (Organon Laboratories Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "34749", "description": "Prempak 1.25 Tablet (Wyeth Pharmaceuticals)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "35091", "description": "Oestrogel Pump-Pack 0.06% gel (Besins Healthcare (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "35198", "description": "Premarin 0.3mg tablets (Pfizer Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3530", "description": "Femoston 1/10mg tablets (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3553", "description": "Femoston 2/10mg tablets (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "35718", "description": "Conjugated oestrogens 300microgram tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "35742", "description": "Estradiol 100micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "35958", "description": "Bedol 2mg tablets (ReSource Medical UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "37033", "description": "Estradiol 75micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "37037", "description": "Estradiol 100micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "37692", "description": "Estradiol 25micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "37697", "description": "Estradiol 50micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "38932", "description": "Evorel 50 patches (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "38935", "description": "Evorel 25 patches (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "38940", "description": "Evorel 75 patches (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "38965", "description": "Evorel 100 patches (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "390", "description": "Climagest 1mg tablets (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "3960", "description": "Conjugated oestrogens 1.25mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "39622", "description": "Hormonin tablets (AMCo)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "40606", "description": "Sandrena 500microgram gel sachets (Orion Pharma (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "40643", "description": "Sandrena 1mg gel sachets (Orion Pharma (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "40836", "description": "Estradiol 500microgram gel sachets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "40848", "description": "Estradiol 1mg gel sachets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "41390", "description": "Estradiol with (estradiol with norethisterone acetate) twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4207", "description": "Elleste Duet 2mg tablets (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4244", "description": "Evorel Sequi patches (Janssen-Cilag Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "42515", "description": "Estradiol 40micrograms/24 hourspatch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4326", "description": "Progynova 2mg tablets (Bayer Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4328", "description": "Elleste Solo 1mg tablets (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4393", "description": "Elleste Duet Conti tablets (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "44461", "description": "Estradiol 10microgram pessaries", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "44494", "description": "Vagifem 10microgram vaginal tablets (Novo Nordisk Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4466", "description": "Progynova TS 50microgram/24hr (3.8mg/unit) Transdermal patch (Schering Health Care Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4467", "description": "Progynova TS 100microgram/24 hr (7.6mg/unit) Transdermal patch (Schering Health Care Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4721", "description": "Estradiol 75micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4882", "description": "Estraderm MX 100 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4909", "description": "Elleste Solo 2mg tablets (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4956", "description": "Estradiol 1mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "49693", "description": "Vagifem 25microgram vaginal tablets (Mawdsley-Brooks & Company Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "49694", "description": "Estraderm TTS 25 patches (DE Pharmaceuticals)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "49757", "description": "FemSeven Conti patches (Lexon (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "4977", "description": "Estraderm MX 75 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "49985", "description": "Femoston-conti 0.5mg/2.5mg tablets (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5005", "description": "Estradiol 50micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5012", "description": "Estradiol 2mg / Norethisterone acetate 1mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "50200", "description": "Climagest 1mg tablets (Sigma Pharmaceuticals Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5100", "description": "Estradiol 25micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "51201", "description": "Estradot 50micrograms/24hours patches (Necessity Supplies Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "51546", "description": "Climaval 2mg tablets (Lexon (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "51688", "description": "Evorel Conti patches (Lexon (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5195", "description": "Femoston-conti 1mg/5mg tablets (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "51978", "description": "Estraderm MX 25 patches (Stephar (U.K.) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "52174", "description": "Estradot 50micrograms/24hours patches (Sigma Pharmaceuticals Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "52306", "description": "Femoston-conti 1mg/5mg tablets (Stephar (U.K.) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "52441", "description": "Evorel Conti patches (DE Pharmaceuticals)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "52480", "description": "Estraderm MX 25 patches (Lexon (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "52632", "description": "Vagifem 25microgram vaginal tablets (Waymade Healthcare Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "52813", "description": "Nuvelle TS Phase I patches (Bayer Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5292", "description": "Fematrix 40 patches (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5343", "description": "Estradiol 25micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "54425", "description": "Oestrogel Pump-Pack 0.06% gel (DE Pharmaceuticals)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "54456", "description": "Estradiol valerate with norgestrel 2mg+500micrograms tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "55551", "description": "Estradiol 500micrograms / Dydrogesterone 2.5mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "56056", "description": "Generic Elleste Duet 1mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "56081", "description": "Generic Femoston 1/10mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "56468", "description": "Oestrogel Pump-Pack 0.06% gel (Waymade Healthcare Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "56480", "description": "Evorel Conti patches (Waymade Healthcare Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "57514", "description": "Estraderm TTS 50 patches (Waymade Healthcare Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "57548", "description": "Oestrogel Pump-Pack 0.06% gel (Sigma Pharmaceuticals Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5755", "description": "Elleste Solo MX 40 transdermal patches (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "57562", "description": "Sandrena 1mg gel sachets (Waymade Healthcare Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "5759", "description": "Estradiol 100micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "57590", "description": "Progynova TS 50 patches (Dowelhurst Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "57615", "description": "Livial 2.5mg tablets (Waymade Healthcare Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "58035", "description": "Generic Elleste Duet 2mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "58516", "description": "Generic Femoston 2/10mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "58575", "description": "Generic Climagest 1mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6030", "description": "Nuvelle Continuous tablets (Bayer Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6041", "description": "Estradiol 0.06% gel", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6059", "description": "Estradiol 100micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "60637", "description": "Climaval 1mg tablets (Lexon (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6082", "description": "FemSeven 75 patches (Teva UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6177", "description": "FemSeven 100 patches (Teva UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6538", "description": "FemTab 2mg tablets (Merck Serono Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6545", "description": "FemSeven Conti patches (Teva UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6563", "description": "Estradiol 75micrograms/24hr once weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6601", "description": "Estradiol 25micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6603", "description": "Estradiol with estrone and estriol tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6622", "description": "Zumenon 2mg tablets (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6793", "description": "Estradiol 40micrograms/24hours transdermal patches", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "6861", "description": "Indivina 1mg/5mg tablets (Orion Pharma (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "7001", "description": "Estradiol valerate 2mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "7175", "description": "Indivina 1mg/2.5mg tablets (Orion Pharma (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "7242", "description": "Estradiol 0.1% gel", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "7251", "description": "FemTab 1mg tablets (Merck Serono Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "7381", "description": "Estradiol 2mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "7388", "description": "Zumenon 1mg tablets (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "7615", "description": "Estradiol 25microgram pessaries", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "774", "description": "Premarin 1.25mg tablets (Pfizer Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "8777", "description": "Dienestrol 1mg tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "8837", "description": "Estradiol 25mg implant", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9047", "description": "Fematrix 80 patches (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9181", "description": "Estring 2mg vaginal ring (Pfizer Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9224", "description": "Norgestrel and conjugated oestrogens (equine) 150micrograms + 625micrograms Tablet", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9235", "description": "Norgestrel and conjugated oestrogens (equine) 150micrograms + 1.25mg Tablet", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9268", "description": "Estradiol 50micrograms/24hr twice weekly patch", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "932", "description": "Conjugated oestrogens 625micrograms/g vaginal cream", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9413", "description": "Estradiol valerate and (estradiol valerate with norethisterone) 1mg with (1mg with 1mg) tablets", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9649", "description": "Elleste Solo MX 80 transdermal patches (Meda Pharmaceuticals Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9671", "description": "Indivina 2mg/5mg tablets (Orion Pharma (UK) Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9684", "description": "Femapak 80 (Abbott Healthcare Products Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "986", "description": "Estraderm TTS 50 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "988", "description": "Estraderm TTS 25 patches (Novartis Pharmaceuticals UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9901", "description": "Progynova TS 100micrograms/24hours transdermal patches (Bayer Plc)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } }, { "code": "9905", "description": "FemSeven Sequi patches (Teva UK Ltd)", "attributes": { "Coding System (CPRD_product_code)": "CPRD_product_code", "Entity type": "res25: P19_HRT_oestrogens", "Category": "drug" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/zfyz-bb82", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1358, "version_name": "HRT Oestrogens (P19)", "version_date": "2021-10-06T16:29:50.673861Z", "is_published": true, "is_latest": true } ] } ]