[ { "phenotype_id": "PH716", "phenotype_version_id": 1432, "name": "Smoking Status", "definition": "OBJECTIVES:\n\nThis study 1) investigated life expectancy and cause-specific mortality rates associated with type 2 diabetes and 2) quantified these relationships in ethnic\nsubgroups.\n\n\nRESEARCH DESIGN AND METHODS:\n\nThis was a cohort study using Clinical Practice Research Datalink data from 383 general practices in Englandwith linked hospitalization andmortality records. A total of 187,968 patients with incident type 2 diabetes from 1998 to 2015 were matched to 908,016 control subjects. Abridged life tables estimated years of life lost, and a competing risk survival model quantified cause-specific hazard ratios (HRs).\n\n\nRESULTS:\n\nA total of 40,286 deaths occurred in patientswith type 2 diabetes. At age 40,white menwith diabetes lost 5 years of life andwhitewomen lost 6 years compared with those without diabetes. A loss of between 1 and 2 years was observed for South Asians and blacks with diabetes. At age older than 65 years, South Asians with diabetes had up to 1.1 years’ longer life expectancy than South Asians without diabetes. Compared with whites with diabetes, South Asians with diabetes had lower adjusted risks formortality fromcardiovascular (HR 0.82; 95% CI 0.75, 0.89), cancer (HR 0.43; 95% CI 0.36, 0.51), and respiratory diseases (HR 0.60; 95% CI 0.48, 0.76). A similar pattern was observed in blacks with diabetes compared with whites with diabetes.\n\n\nCONCLUSIONS:\n\nType 2 diabetes was associated with more years of life lost among whites than among South Asians or blacks, with older South Asians experiencing longer life expectancy compared with South Asians without diabetes. The findings support optimized cardiovascular disease risk factor management, especially in whites with type 2 diabetes.\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft, Life Expectancy and Cause-Specific Mortality in Type 2 Diabetes A Population-Based Cohort Study Quantifying Relationships in Ethnic Subgroups. Diabetes Care, 40(3), 338-345, 2017." } ], "validation": "", "citation_requirements": "", "created": "2021-10-06T16:32:10.903516Z", "author": "Alison K Wright, Evangelos Kontopantelis, Richard Emsley, Iain Buchan, Naveed Sattar, Martin K Rutter, Darren M. Ashcroft", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2021-10-06T16:32:10.903543Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Lifestyle risk factor", "value": "4" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 } ], "coding_system": [ { "name": "Read codes v2", "value": 5 } ], "event_date_range": "01/01/1998 - 31/03/2015", "concept_information": [ { "concept_id": 2136, "concept_version_id": 5410, "concept_name": "Smoking Status - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH716", "phenotype_version_id": 1432, "phenotype_name": "Smoking Status", "code_attribute_header": [ "Entity type", "Category", "Coding System (Read)" ], "codes": [ { "code": "137..00", "description": "Tobacco consumption", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1371", "description": "Never smoked tobacco", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137..11", "description": "Smoker - amount smoked", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1371.11", "description": "Non-smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1372", "description": "Trivial smoker - < 1 cig/day", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1372.11", "description": "Occasional smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1373", "description": "Light smoker - 1-9 cigs/day", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1374", "description": "Moderate smoker - 10-19 cigs/d", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1375", "description": "Heavy smoker - 20-39 cigs/day", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1376", "description": "Very heavy smoker - 40+cigs/d", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1377", "description": "Ex-trivial smoker (<1/day)", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1378", "description": "Ex-light smoker (1-9/day)", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "1379", "description": "Ex-moderate smoker (10-19/day)", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137a.00", "description": "Pipe tobacco consumption", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137A.00", "description": "Ex-heavy smoker (20-39/day)", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137b.00", "description": "Ready to stop smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137B.00", "description": "Ex-very heavy smoker (40+/day)", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137c.00", "description": "Thinking about stopping smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137C.00", "description": "Keeps trying to stop smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137d.00", "description": "Not interested in stopping smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137D.00", "description": "Admitted tobacco cons untrue ?", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137e.00", "description": "Smoking restarted", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137E.00", "description": "Tobacco consumption unknown", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137F.00", "description": "Ex-smoker - amount unknown", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137G.00", "description": "Trying to give up smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137H.00", "description": "Pipe smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137I.00", "description": "Passive smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137j.00", "description": "Ex-cigarette smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137J.00", "description": "Cigar smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137K.00", "description": "Stopped smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137K000", "description": "Recently stopped smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137l.00", "description": "Ex roll-up cigarette smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137L.00", "description": "Current non-smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137m.00", "description": "Failed attempt to stop smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137M.00", "description": "Rolls own cigarettes", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137N.00", "description": "Ex pipe smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137O.00", "description": "Ex cigar smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137P.00", "description": "Cigarette smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137P.11", "description": "Smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137Q.00", "description": "Smoking started", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137Q.11", "description": "Smoking restarted", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137R.00", "description": "Current smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137S.00", "description": "Ex smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137T.00", "description": "Date ceased smoking", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137U.00", "description": "Not a passive smoker", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137V.00", "description": "Smoking reduced", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137W.00", "description": "Chews tobacco", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137X.00", "description": "Cigarette consumption", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137Y.00", "description": "Cigar consumption", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "137Z.00", "description": "Tobacco consumption NOS", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8CAL.00", "description": "Smoking cessation advice", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8H7i.00", "description": "Referral to smoking cessation advisor", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8HkQ.00", "description": "Referral to NHS stop smoking service", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8HTK.00", "description": "Referral to stop-smoking clinic", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "8IAj.00", "description": "Smoking cessation advice declined", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9km..00", "description": "Ex-smoker annual review - enhanced services administration", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9km..11", "description": "Ex-smoker annual review", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9kn..00", "description": "Non-smoker annual review - enhanced services administration", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9kn..11", "description": "Non-smoker annual review", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9ko..00", "description": "Current smoker annual review - enhanced services admin", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9ko..11", "description": "Current smoker annual review", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } }, { "code": "9NS0200", "description": "Referral for smoking cessation service offered", "attributes": { "Entity type": "res56: smoking status", "Category": "diagnostic", "Coding System (Read)": "Read" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/3np7-7q21", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1432, "version_name": "Smoking Status", "version_date": "2021-10-06T16:32:10.931968Z", "is_published": true, "is_latest": true } ] } ]