[ { "phenotype_id": "PH833", "phenotype_version_id": 1745, "name": "Hba1C", "definition": "We generated a cohort of 25 million patients from 1831 UK general practices registered with the Clinical Practice Research Datalink (CPRD) Aurum (inEngland) and CPRD GOLD (in Northern Ireland, Scotland, and Wales) databases. The cohort included 14 929 251 patients (median age 41 years [IQR 25–59]; 7 461 565 [50·0%] of whom were women), who were followed between March 1 and Dec 10, 2020. We aimed to compare: (1) the UK-wide incidence of type 2 diabetes; (2) the frequency of HbA1c testing; and (3) mortality in people with type 2 diabetes, by nation, before and after the first nationwide COVID-19 lockdown, which began in March 23, 2020 (appendix pp 1–3). There were 790 377 (5·3%) people with type 2 diabetes in the cohort (median age 67 years (IQR 57–76); 348 515 (44·1%) of whom were women).\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter, Impact of COVID-19 on diagnoses, monitoring, and mortality in people with type 2 diabetes in the UK. The Lancet Diabetes Endocrinology, 9, 2021." } ], "validation": "", "citation_requirements": "", "created": "2022-04-04T07:06:11.268976Z", "author": "Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2022-04-04T07:06:11.268999Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Disease or syndrome", "value": "2" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD GOLD", "value": 5, "uid": "a29feafa-7bdd-44e9-b977-c9d26425e67f", "url": "https://healthdatagateway.org/en/dataset/694", "datasource_id": 694 }, { "name": "CPRD Aurum", "value": 6, "uid": "1d574c14-1af0-490d-9c4e-be88cfd0e345", "url": "https://healthdatagateway.org/en/dataset/692", "datasource_id": 692 } ], "coding_system": [ { "name": "Read codes v2", "value": 5 }, { "name": "SNOMED CT codes", "value": 9 } ], "event_date_range": "01/01/2010 - 29/02/2020", "concept_information": [ { "concept_id": 2589, "concept_version_id": 6591, "concept_name": "Hba1C - Primary Care", "coding_system": { "id": 5, "name": "Read codes v2", "description": "Read codes v2" }, "phenotype_id": "PH833", "phenotype_version_id": 1745, "phenotype_name": "Hba1C", "code_attribute_header": [ "Entity type", "Coding System (Read SNOMED)", "Category" ], "codes": [ { "code": "423..00", "description": "Haemoglobin estimation", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "423..11", "description": "Hb estimation", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42c..00", "description": "HbA1 - diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42c0.00", "description": "HbA1 < 7% - good control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42c1.00", "description": "HbA1 7 - 10% - borderline control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42c2.00", "description": "HbA1 > 10% - bad control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42c3.00", "description": "HbA1 level (DCCT aligned)", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42V2.00", "description": "Haemoglobin A", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42V2000", "description": "Haemoglobin A quantitation", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42VA.00", "description": "Haemoglobin variant test", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W..00", "description": "Hb. A1C - diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W1.00", "description": "Hb. A1C < 7% - good control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W..11", "description": "Glycosylated Hb", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W..12", "description": "Glycated haemoglobin", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W2.00", "description": "Hb. A1C 7-10% - borderline", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W3.00", "description": "Hb. A1C > 10% - bad control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W4.00", "description": "HbA1c level (DCCT aligned)", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42W5.00", "description": "Haemoglobin A1c level - IFCC standardised", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "42WZ.00", "description": "Hb. A1C - diabetic control NOS", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44T1200", "description": "Random blood sugar raised", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44T2.00", "description": "Fasting blood sugar", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44TB.00", "description": "Haemoglobin A1c level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44TB000", "description": "Haemoglobin A1c (diagnostic reference range)", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44TB100", "description": "Haemoglobin A1c (monitoring ranges)", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44TC.00", "description": "Haemoglobin A1 level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44TJ.00", "description": "Blood glucose level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44TK.00", "description": "Fasting blood glucose level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44TL.00", "description": "Total glycosylated haemoglobin level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44U..00", "description": "Blood glucose result", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44U..11", "description": "Blood sugar result", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44U5.00", "description": "Blood glucose 7-9.9 mmol/L", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "44U6.00", "description": "Blood glucose 10-13.9 mmol/L", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "66Ae.00", "description": "HBA1c target", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "66Ae000", "description": "HbA1c target level - IFCC standardised", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "C109711", "description": "Type II diabetes mellitus - poor control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } }, { "code": "C10F711", "description": "Type II diabetes mellitus - poor control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "Read", "Category": "test" } } ] }, { "concept_id": 2590, "concept_version_id": 6593, "concept_name": "Hba1C - Primary Care", "coding_system": { "id": 9, "name": "SNOMED CT codes", "description": "SNOMED CT codes" }, "phenotype_id": "PH833", "phenotype_version_id": 1745, "phenotype_name": "Hba1C", "code_attribute_header": [ "Entity type", "Coding System (Read SNOMED)", "Category" ], "codes": [ { "code": "1.09871E+14", "description": "Test request : Haemoglobin A1c", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "1.29761E+14", "description": "Haemoglobin A1c level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "1.72528E+15", "description": "HbA1c (haemoglobin A1c) target - IFCC (International Federation of Clinical Chemistry and Laboratory", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "1.72875E+15", "description": "Haemoglobin A1c target - International Federation of Clinical Chemistry and Laboratory Medicine stan", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "1.92779E+15", "description": "Raised HbA1c level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2160141012", "description": "HBA1c target", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2163995019", "description": "Target HbA1c level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2621920018", "description": "Haemoglobin A1c (HBA1c) target", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2621921019", "description": "Hemoglobin A1c (HBA1c) target", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2.64314E+15", "description": "HbA1c level (monitoring ranges) - IFCC standardised", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2.6431E+15", "description": "HbA1c level (diagnostic reference range) - IFCC standardised", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2767753013", "description": "Haemoglobin A1c (HbA1c) greater than 10% indicating poor diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2767755018", "description": "Hemoglobin A1c greater than 10% indicating poor diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2768431010", "description": "Hemoglobin A1c between 7%-10% indicating borderline diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2769803019", "description": "Hemoglobin A1c less than 7% indicating good diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2770714019", "description": "Hemoglobin A1c (HbA1c) between 7%-10% indicating borderline diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2772122013", "description": "Hemoglobin A1c (HbA1c) less than 7% indicating good diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2772787010", "description": "Haemoglobin A1c (HbA1c) between 7%-10% indicating borderline diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2773408014", "description": "Hemoglobin A1c (HbA1c) greater than 10% indicating poor diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2773783018", "description": "Haemoglobin A1c (HbA1c) less than 7% indicating good diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2883676014", "description": "Hemoglobin A1c target value using International Federation of Clinical Chemistry and Laboratory Medi", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2883677017", "description": "Haemoglobin A1c target value using International Federation of Clinical Chemistry and Laboratory Med", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "2914480010", "description": "Hemoglobin A1c target", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "404443010", "description": "Hemoglobin A1C - diabetic control interpretation", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "4.59526E+15", "description": "Haemoglobin A1c less than 7% indicating good diabetic control", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "489331011", "description": "Hemoglobin A1C - diabetic control finding", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "493589010", "description": "HbA1c - Haemoglobin A1c level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "493590018", "description": "HbA1c - Hemoglobin A1c level", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "72394011", "description": "Hemoglobin A1c measurement", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } }, { "code": "72395012", "description": "Haemoglobin A1c measurement", "attributes": { "Entity type": "res166: HbA1c", "Coding System (Read SNOMED)": "SNOMED", "Category": "test" } } ] } ], "status": 2, "doi": "https://doi.org/10.48533/ymby-yw60", "is_deleted": null, "publish_status": 2, "owner": "ieuan.scanlon", "template": { "id": 1, "name": "Clinical-Coded Phenotype", "description": "Phenotype definitions that are based on lists of clinical codes, or algorithms using clinical codes.", "version_id": 1 }, "versions": [ { "version_id": 1745, "version_name": "Hba1C", "version_date": "2022-04-04T07:06:11.306196Z", "is_published": true, "is_latest": true } ] } ]