[ { "phenotype_id": "PH834", "phenotype_version_id": 1747, "name": "Insulin", "definition": "We generated a cohort of 25 million patients from 1831 UK general practices registered with the Clinical Practice Research Datalink (CPRD) Aurum (inEngland) and CPRD GOLD (in Northern Ireland, Scotland, and Wales) databases. The cohort included 14 929 251 patients (median age 41 years [IQR 25–59]; 7 461 565 [50·0%] of whom were women), who were followed between March 1 and Dec 10, 2020. We aimed to compare: (1) the UK-wide incidence of type 2 diabetes; (2) the frequency of HbA1c testing; and (3) mortality in people with type 2 diabetes, by nation, before and after the first nationwide COVID-19 lockdown, which began in March 23, 2020 (appendix pp 1–3). There were 790 377 (5·3%) people with type 2 diabetes in the cohort (median age 67 years (IQR 57–76); 348 515 (44·1%) of whom were women).\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter, Impact of COVID-19 on diagnoses, monitoring, and mortality in people with type 2 diabetes in the UK. The Lancet Diabetes Endocrinology, 9, 2021." } ], "validation": "", "citation_requirements": "", "created": "2022-04-04T07:06:14.713942Z", "author": "Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2022-04-04T07:06:14.713966Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Drug", "value": "3" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD Aurum", "value": 6, "uid": "1d574c14-1af0-490d-9c4e-be88cfd0e345", "url": "https://healthdatagateway.org/en/dataset/692", "datasource_id": 692 } ], "coding_system": [ { "name": "GPRD product codes", "value": 14 } ], "event_date_range": "01/01/2010 - 29/02/2020", "concept_information": [ { "concept_id": 2591, "concept_version_id": 6595, "concept_name": "Insulin - Primary Care", "coding_system": { "id": 14, "name": "GPRD product codes", "description": "GPRD product codes" }, "phenotype_id": "PH834", "phenotype_version_id": 1747, "phenotype_name": "Insulin", "code_attribute_header": [ "Entity type", "Coding System (CPRD_product_code)", "Category" ], "codes": [ { "code": "1.00445e+16", "description": "Insulin degludec 100units/ml / Liraglutide 3.6mg/ml solution for injection 3ml pre-filled disposable", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.00446e+16", "description": "Xultophy 100units/ml / 3.6mg/ml solution for injection 3ml pre-filled pens (Novo Nordisk Ltd)", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.02526e+16", "description": "Insulin lispro 200units/ml solution for injection 3ml pre-filled disposable devices", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.02527e+16", "description": "Humalog KwikPen 200units/ml solution for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.04942e+16", "description": "Insulin glargine 300units/ml solution for injection 1.5ml pre-filled disposable devices", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.04944e+16", "description": "Toujeo 300units/ml solution for injection 1.5ml pre-filled SoloStar pens (Sanofi)", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1052940000000000.0", "description": "Human Mixtard 10 Injection", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1053040000000000.0", "description": "Human Mixtard 20 Injection", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1053140000000000.0", "description": "Human Mixtard 40 Injection", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1053240000000000.0", "description": "Human Mixtard 50 Injection", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1053540000000000.0", "description": "Human Mixtard 30 Injection (cartridges) 100 u/ml", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06006e+16", "description": "Abasaglar 100units/ml solution for injection 3ml cartridges (Eli Lilly and Company Ltd)", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06007e+16", "description": "Abasaglar KwikPen 100units/ml solution for injection 3ml pre-filled pens (Eli Lilly and Company Ltd)", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1061640000000000.0", "description": "Human Mixtard 30 Preloaded pen", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1061740000000000.0", "description": "Human Mixtard 10 Preloaded pen", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1061840000000000.0", "description": "Human Mixtard 20 Preloaded pen", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1061940000000000.0", "description": "Human Mixtard 40 Preloaded pen", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1062040000000000.0", "description": "Human Mixtard 50 Preloaded pen", "attributes": { "Entity type": "res166: Insulin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06739e+16", "description": "Insulin human 100units/ml solution for injection 10ml vials", "attributes": { "Entity type": "res166: Insulin (CPRD 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