[ { "phenotype_id": "PH836", "phenotype_version_id": 1751, "name": "Metformin", "definition": "We generated a cohort of 25 million patients from 1831 UK general practices registered with the Clinical Practice Research Datalink (CPRD) Aurum (inEngland) and CPRD GOLD (in Northern Ireland, Scotland, and Wales) databases. The cohort included 14 929 251 patients (median age 41 years [IQR 25–59]; 7 461 565 [50·0%] of whom were women), who were followed between March 1 and Dec 10, 2020. We aimed to compare: (1) the UK-wide incidence of type 2 diabetes; (2) the frequency of HbA1c testing; and (3) mortality in people with type 2 diabetes, by nation, before and after the first nationwide COVID-19 lockdown, which began in March 23, 2020 (appendix pp 1–3). There were 790 377 (5·3%) people with type 2 diabetes in the cohort (median age 67 years (IQR 57–76); 348 515 (44·1%) of whom were women).\n\n\n\n\n\n\n\n\n", "implementation": "", "publications": [ { "doi": null, "details": "Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter, Impact of COVID-19 on diagnoses, monitoring, and mortality in people with type 2 diabetes in the UK. The Lancet Diabetes Endocrinology, 9, 2021." } ], "validation": "", "citation_requirements": "", "created": "2022-04-04T07:06:21.562055Z", "author": "Matthew J Carr, Alison K Wright, Lalantha Leelarantha, Hood Thabit, Nicola Milne, Naresh Kanumilli, Darren M Ashcroft, Martin K Rutter", "collections": [ { "name": "ClinicalCodes Repository", "value": 25 }, { "name": "Phenotype Library", "value": 18 } ], "tags": null, "organisation": null, "world_access": 1, "updated": "2022-04-04T07:06:21.562105Z", "sex": [ { "name": "Both", "value": "3" } ], "type": [ { "name": "Drug", "value": "3" } ], "ontology": null, "phenoflowid": "", "data_sources": [ { "name": "CPRD Aurum", "value": 6, "uid": "1d574c14-1af0-490d-9c4e-be88cfd0e345", "url": "https://healthdatagateway.org/en/dataset/692", "datasource_id": 692 } ], "coding_system": [ { "name": "GPRD product codes", "value": 14 } ], "event_date_range": "01/01/2010 - 29/02/2020", "concept_information": [ { "concept_id": 2593, "concept_version_id": 6599, "concept_name": "Metformin - Primary Care", "coding_system": { "id": 14, "name": "GPRD product codes", "description": "GPRD product codes" }, "phenotype_id": "PH836", "phenotype_version_id": 1751, "phenotype_name": "Metformin", "code_attribute_header": [ "Entity type", "Coding System (CPRD_product_code)", "Category" ], "codes": [ { "code": "1017140000000000.0", "description": "Orabet Tablets 500 mg", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1017240000000000.0", "description": "Orabet Tablets 850 mg", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.05988e+16", "description": "Glucient SR 750mg tablets (Consilient Health Ltd)", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.05989e+16", "description": "Glucient SR 1000mg tablets (Consilient Health Ltd)", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06141e+16", "description": "Empagliflozin 5mg / Metformin 850mg tablets", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06142e+16", "description": "Empagliflozin 5mg / Metformin 1g tablets", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06143e+16", "description": "Empagliflozin 12.5mg / Metformin 850mg tablets", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06144e+16", "description": "Empagliflozin 12.5mg / Metformin 1g tablets", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06145e+16", "description": "Synjardy 5mg/850mg tablets (Boehringer Ingelheim Ltd)", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06146e+16", "description": "Synjardy 5mg/1000mg tablets (Boehringer Ingelheim Ltd)", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06147e+16", "description": "Synjardy 12.5mg/850mg tablets (Boehringer Ingelheim Ltd)", "attributes": { "Entity type": "res166: Metformin (CPRD Aurum)", "Coding System (CPRD_product_code)": "CPRD_product_code", "Category": "drug" } }, { "code": "1.06148e+16", "description": "Synjardy 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