[
  {
    "phenotype_id": "PH932",
    "phenotype_version_id": 4045,
    "name": "Attention-Deficit hyperactivity disorder (ADHD)",
    "definition": "Attention-Deficit hyperactivity disorder (ADHD) is a neurodevelopmental condition with secondary behavioural, social, and educational difficulties. ADHD is defined as a behavioural syndrome characterized by the core symptoms of hyperactivity, impulsivity, and inattention which can lead to psychological, social, education, or occupational impairment. The ADHD phenotype includes hyperkinetic disorder, hyperkinetic conduct disorder, attention-deficit hyperactivity disorder and disturbance of activity and attention.\n\n# ICD-10 definition\nThis definition has been previously validated and published (John et al, 2022; Martin et al, 2024).\n\n# Read codes definition\nThis definition also includes disturbance of activity and attention, attention deficit with/without hyperactivity, and ADHD treatment, management and monitoring. This definition has been previously validated and published (John et al, 2022; Martin et al, 2024).\n\n# SNOMED CT definition\nThis definition has been created by mapping the existing Read code and ICD-10 definitions and additional exploration of SNOMED CT codes. It excludes non-specific definitions of neurodevelopmental disorders, developmental delay, attentional delay and measurement codes for ADHD medication/prescription.\n\nAn auxiliary concept “*ADHD assessments*” is provided to help identify individuals being assessed for ADHD.\n\n__Warning: The SNOMED CT definition have not undergone validation yet.__\n\n# References\n[John, A., Friedmann, Y., DelPozo-Banos, M., Frizzati, A., Ford, T., & Thapar, A. (2022).](https://doi.org/10.1016/S2215-0366(21)00367-9 ) Association of school absence and exclusion with recorded neurodevelopmental disorders, mental disorders, or self-harm: a nationwide, retrospective, electronic cohort study of children and young people in Wales, UK. The Lancet Psychiatry, 9(1), 23-34.\n\n[Martin, J., Langley, K., Cooper, M., Rouquette, O.Y., John, A., Sayal, K., Ford, T. and Thapar, A. (2024).](https://doi.org/10.1111/jcpp.13987) Sex differences in attention-deficit hyperactivity disorder diagnosis and clinical care: a national study of population healthcare records in Wales. J Child Psychol Psychiatr.",
    "implementation": "",
    "publications": [
      {
        "doi": "10.1016/S2215-0366(21)00367-9",
        "details": "John,A., Friedmann, Y., DelPozo-Banos, M., Frizzati, A., Ford, T., & Thapar, A.(2022). Association of school absence and exclusion with recorded neurodevelopmental disorders, mental disorders, or self-harm: a nationwide, retrospective, electronic cohort study of children and young people in Wales, UK. The Lancet Psychiatry. Volume 9, Issue 1,2022,Pages 23-34,ISSN 2215-0366, https://doi.org/10.1016/S2215-0366(21)00367-9"
      }
    ],
    "validation": "None",
    "citation_requirements": "John, A., Friedmann, Y., DelPozo-Banos, M., Frizzati, A., Ford, T., & Thapar, A. (2022). Association of school absence and exclusion with recorded neurodevelopmental disorders, mental disorders, or self-harm: a nationwide, retrospective, electronic cohort study of children and young people in Wales, UK. The Lancet Psychiatry, 9(1), 23-34.",
    "created": "2022-05-05T08:17:23.584774Z",
    "author": "A. John, Y. Friedmann, M. DelPozo-Banos, A. Frizzati, T. Ford, A. Thapar",
    "collections": [
      {
        "name": "Adolescent Data Platform (ADP)",
        "value": 23
      },
      {
        "name": "DATAMIND",
        "value": 27
      },
      {
        "name": "Phenotype Library",
        "value": 18
      }
    ],
    "tags": null,
    "organisation": {
      "id": 2,
      "slug": "adp",
      "name": "ADP"
    },
    "world_access": 2,
    "updated": "2024-07-23T09:51:56.838447Z",
    "sex": [
      {
        "name": "Both",
        "value": "3"
      }
    ],
    "type": [
      {
        "name": "Disease or syndrome",
        "value": "2"
      }
    ],
    "ontology": null,
    "phenoflowid": null,
    "data_sources": [
      {
        "name": "Welsh Longitudinal General Practice Dataset (WLGP) - Welsh Primary Care",
        "value": 502,
        "uid": "33fc3ffd-aa4c-4a16-a32f-0c900aaea3d2",
        "url": "https://healthdatagateway.org/en/dataset/355",
        "datasource_id": 355
      },
      {
        "name": "Patient Episode Dataset for Wales (PEDW)",
        "value": 40,
        "uid": "4c33a5d2-164c-41d7-9797-dc2b008cc852",
        "url": "https://healthdatagateway.org/en/dataset/318",
        "datasource_id": 318
      }
    ],
    "coding_system": [
      {
        "name": "SNOMED  CT codes",
        "value": 9
      },
      {
        "name": "ICD10 codes",
        "value": 4
      },
      {
        "name": "Read codes v2",
        "value": 5
      }
    ],
    "event_date_range": "",
    "concept_information": [
      {
        "concept_id": 2708,
        "concept_version_id": 11046,
        "concept_name": "Attention-Deficit Hyperactivity Disorder (ADHD)",
        "coding_system": {
          "id": 5,
          "name": "Read codes v2",
          "description": "Read codes v2"
        },
        "phenotype_id": "PH932",
        "phenotype_version_id": 4045,
        "phenotype_name": "Attention-Deficit hyperactivity disorder (ADHD)",
        "code_attribute_header": [
          "Prescriptions"
        ],
        "codes": [
          {
            "code": "6A61.",
            "description": "adhd annual review | attention deficit hyperactivity disorder annual review",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "8BPT.",
            "description": "drug therapy for adhd | drug therapy adhd (attention deficit hyperactivity disorder) | drug therapy for adhd (attention deficit hyperactivity disorder)",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "8BPT0",
            "description": "stimulant drug therapy adhd | stimulant drug therapy for adhd | stimulant drug therapy for adhd (attention deficit hyperactivity disorder)",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "8BPT1",
            "description": "non-stimulnt drug therapy adhd | non-stimulant drug therapy for adhd | non-stimulant drug therapy for adhd (attention deficit hyperactivity disorder)",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "9Ngp.",
            "description": "on drug therapy adhd | on drug ther adhd (attention deficit hyperactivity disorder) | on drug therapy for adhd (attention deficit hyperactivity disorder)",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "9Ngp0",
            "description": "on stimulant drug therapy adhd | on stim drug ther adhd (attention def hyperactivity disordr) | on stimulant drug therapy for adhd (attention deficit hyperactivity disorder)",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "9Ngp1",
            "description": "on non-stimulnt drug ther adhd | on non-stimulant drug therapy for adhd | on non-stimulant drug therapy for adhd (attention deficit hyperactivity disorder)",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "9Ol8.",
            "description": "adhd monitr invitatn 1st lettr | adhd monitoring invitation first letter | attention deficit hyperactivity disorder monitoring invitation first letter",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "9Ol9.",
            "description": "adhd monitr invitatn 2nd lettr | adhd monitoring invitation second letter | attention deficit hyperactivity disorder monitoring invitation second letter",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "9OlA.",
            "description": "adhd monitr invitatn 3rd lettr | adhd monitoring invitation third letter | attention deficit hyperactivity disorder monitoring invitation third letter",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "dc1..",
            "description": "dexamfetamine sulphate",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc11.",
            "description": "*dexedrine 5mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc12.",
            "description": "*durophet 7.5mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc13.",
            "description": "*durophet 12.5mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc14.",
            "description": "*durophet 20mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc1w.",
            "description": "dexamfetamine sulph 5mg tabs | dexamfetamine sulphate 5mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc1x.",
            "description": "*dexamphetamine 7.5mg m/r caps | dexamphetamine sulphate 7.5mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc1y.",
            "description": "*dexamphetamine 12.5mg caps | dexamphetamine sulphate 12.5mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dc1z.",
            "description": "*dexamphetamine 20mg m/r caps | dexamphetamine sulphate 20mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1..",
            "description": "methylphenidate",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw11.",
            "description": "methylphenidate hcl 10mg tabs | methylphenidate hydrochloride 10mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw12.",
            "description": "ritalin 10mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw13.",
            "description": "*equasym 5mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw14.",
            "description": "*equasym 20mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw15.",
            "description": "*equasym 10mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw16.",
            "description": "equasym xl 20mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw17.",
            "description": "concerta xl 18mg m/r tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw18.",
            "description": "concerta xl 36mg m/r tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw19.",
            "description": "*tranquilyn 5mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1A.",
            "description": "*tranquilyn 10mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1B.",
            "description": "*tranquilyn 20mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1C.",
            "description": "equasym xl 10mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1D.",
            "description": "equasym xl 30mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1E.",
            "description": "medikinet xl 10mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1F.",
            "description": "medikinet xl 20mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1G.",
            "description": "medikinet xl 30mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1H.",
            "description": "medikinet xl 40mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1I.",
            "description": "concerta xl 27mg m/r tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1J.",
            "description": "medikinet 5mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1K.",
            "description": "medikinet 10mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1L.",
            "description": "medikinet 20mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1M.",
            "description": "medikinet xl 5mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1q.",
            "description": "methylphenidate 5mg m/r caps | methylphenidate hydrochloride 5mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1r.",
            "description": "methylphenidate 27mg m/r tabs | methylphenidate hydrochloride 27mg m/r tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1s.",
            "description": "methylphenidate 40mg m/r caps | methylphenidate hydrochloride 40mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1t.",
            "description": "methylphenidate 10mg m/r caps | methylphenidate hydrochloride 10mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1u.",
            "description": "methylphenidate 30mg m/r caps | methylphenidate hydrochloride 30mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1v.",
            "description": "methylphenidate 36mg m/r tabs | methylphenidate hydrochloride 36mg m/r tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1w.",
            "description": "methylphenidate 18mg m/r tabs | methylphenidate hydrochloride 18mg m/r tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1x.",
            "description": "methylphenidate 20mg m/r caps | methylphenidate hydrochloride 20mg m/r capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1y.",
            "description": "methylphenidate hcl 5mg tabs | methylphenidate hydrochloride 5mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw1z.",
            "description": "methylphenidate hcl 20mg tabs | methylphenidate hydrochloride 20mg tablets",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw2..",
            "description": "atomoxetine",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw21.",
            "description": "strattera 10mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw22.",
            "description": "strattera 18mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw23.",
            "description": "strattera 25mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw24.",
            "description": "strattera 40mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw25.",
            "description": "strattera 60mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw26.",
            "description": "strattera 80mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw2u.",
            "description": "atomoxetine 80mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw2v.",
            "description": "atomoxetine 60mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw2w.",
            "description": "atomoxetine 40mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw2x.",
            "description": "atomoxetine 25mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw2y.",
            "description": "atomoxetine 18mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw2z.",
            "description": "atomoxetine 10mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw3..",
            "description": "lisdexamfetamine",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw31.",
            "description": "elvanse 30mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw32.",
            "description": "elvanse 50mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw33.",
            "description": "elvanse 70mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw3x.",
            "description": "lisdexamfetamine dim 70mg caps | lisdexamfetamine dimesylate 70mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw3y.",
            "description": "lisdexamfetamine dim 50mg caps | lisdexamfetamine dimesylate 50mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw3z.",
            "description": "lisdexamfetamine dim 30mg caps | lisdexamfetamine dimesylate 30mg capsules",
            "attributes": {
              "Prescriptions": "prescriptions"
            }
          },
          {
            "code": "dw4..",
            "description": "Guanfacine",
            "attributes": null
          },
          {
            "code": "dw41.",
            "description": "INTUNIV 1mg m/r tablets",
            "attributes": null
          },
          {
            "code": "dw42.",
            "description": "GUANFACINE 1mg m/r tablets",
            "attributes": null
          },
          {
            "code": "dw43.",
            "description": "INTUNIV 2mg m/r tablets",
            "attributes": null
          },
          {
            "code": "dw44.",
            "description": "GUANFACINE 2mg m/r tablets",
            "attributes": null
          },
          {
            "code": "dw45.",
            "description": "INTUNIV 3mg m/r tablets",
            "attributes": null
          },
          {
            "code": "dw46.",
            "description": "GUANFACINE 3mg m/r tablets",
            "attributes": null
          },
          {
            "code": "dw47.",
            "description": "INTUNIV 4mg m/r tablets",
            "attributes": null
          },
          {
            "code": "dw48.",
            "description": "GUANFACINE 4mg m/r tablets",
            "attributes": null
          },
          {
            "code": "E2E..",
            "description": "childhood hyperkinetic syndr. | childhood hyperkinetic syndrome",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2E0.",
            "description": "child attention deficit disord | child attention deficit disorder",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2E00",
            "description": "attention deficit-not hyperact | attention deficit without hyperactivity",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2E01",
            "description": "attention deficit +hyperactive | attention deficit with hyperactivity",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2E0z",
            "description": "child attent.deficit dis.nos | child attention deficit disorder nos",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2E1.",
            "description": "hyperkinesis+development delay | hyperkinesis with developmental delay",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2E2.",
            "description": "hyperkinetic conduct disorder",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2Ey.",
            "description": "other hyperkinetic manifestat. | other hyperkinetic manifestation",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "E2Ez.",
            "description": "hyperkinetic syndrome nos",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "Eu90.",
            "description": "[x]hyperkinetic disorders",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "Eu900",
            "description": "[x]disturbance activity/attntn | [x]disturbance of activity and attention",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "Eu901",
            "description": "[x]hyperkinetic conduct disord | [x]hyperkinetic conduct disorder",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "Eu902",
            "description": "[x]def atten motor cont percep | [x]deficits in attention, motor control and perception",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "Eu90y",
            "description": "[x]oth hyperkinetic disorders | [x]other hyperkinetic disorders",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "Eu90z",
            "description": "[x]hyperkinetic disorder, unsp | [x]hyperkinetic disorder, unspecified",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "Eu9y7",
            "description": "[x]attention deficit disorder",
            "attributes": {
              "Prescriptions": ""
            }
          },
          {
            "code": "ZS91.",
            "description": "attention deficil disorder",
            "attributes": {
              "Prescriptions": ""
            }
          }
        ]
      },
      {
        "concept_id": 2931,
        "concept_version_id": 11047,
        "concept_name": "Attention-Deficit Hyperactivity Disorder (ADHD)",
        "coding_system": {
          "id": 4,
          "name": "ICD10 codes",
          "description": "ICD10 Codes"
        },
        "phenotype_id": "PH932",
        "phenotype_version_id": 4045,
        "phenotype_name": "Attention-Deficit hyperactivity disorder (ADHD)",
        "code_attribute_header": null,
        "codes": [
          {
            "code": "F90",
            "description": "hyperkinetic disorders",
            "attributes": null
          },
          {
            "code": "F90.0",
            "description": "disturbance of activity and attention",
            "attributes": null
          },
          {
            "code": "F90.1",
            "description": "hyperkinetic conduct disorder",
            "attributes": null
          },
          {
            "code": "F90.2",
            "description": "attention-deficit hyperactivity disorder, combined type",
            "attributes": null
          },
          {
            "code": "F90.8",
            "description": "other hyperkinetic disorders",
            "attributes": null
          },
          {
            "code": "F90.9",
            "description": "hyperkinetic disorder, unspecified",
            "attributes": null
          }
        ]
      },
      {
        "concept_id": 3698,
        "concept_version_id": 11048,
        "concept_name": "Attention-Deficit Hyperactivity Disorder (ADHD)",
        "coding_system": {
          "id": 9,
          "name": "SNOMED  CT codes",
          "description": "SNOMED CT codes"
        },
        "phenotype_id": "PH932",
        "phenotype_version_id": 4045,
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