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Landau-Kleffner Syndrome (MONDO:0009509)

Open Trait in OLS

A rare form of epileptic encephalopathy with spike-wave activation in sleep (EE-SWAS) characterized by various combinations of acquired cognitive, language, behavioral, and motor deficits associated with marked spike- and- wave activation in sleep. In Landau-Kleffner syndrome, receptive language is mainly affected, with an acquired auditory verbal agnosia.

Overview

Category

syndromic disease

nervous system disorder

Ontology ID

Internal:10734

Synonyms

LKS

Landau-Kleffner syndrome

acquired epileptic aphasia

FESD

Rolandic epilepsy, intellectual disability, and speech dyspraxia, autosomal dominant

Rolandic epilepsy, mental retardation, and speech dyspraxia, autosomal dominant

acquired aphasia with convulsive disorder

acquired epileptiform aphasia

aphasia, acquired, with epilepsy

benign epilepsy of childhood with centrotemporal spikes

continuous Spike and waves during slow-Wave sleep syndrome

epilepsy, focal, with speech disorder and with or without impaired intellectual development

epilepsy, focal, with speech disorder and with or without intellectual disability

epilepsy, focal, with speech disorder and with or without mental retardation

Mapped terms

DOID:2538

EFO:1001010

GARD:0006855

MEDGEN:79465

MESH:D018887

MedDRA:10052075

MedDRA:10052083

NANDO:1200602

NCIT:C84806

Orphanet:98818

SCTID:230438007

UMLS:C0282512

icd11.foundation:348544271

Child terms

Unknown children.