Phenotype Library | phenotype: CCU002

CCU002_02 Depression

CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow

PH1005

Version ID

2183

Type

Disease or Syndrome

Data Sources

GPES Data for Pandemic Planning and Research (COVID-19) , Hospital Episode Statistics Admitted Patient Care , Civil Registration - Deaths , Trusted Research Environments for CVD-COVID-UK / COVID-IMPACT , Secondary Uses Services Payment By Results

Valid event data range

08/12/2020 - 18/03/2021

Sex

♀ Female ♂ Male

Agreement Date

2021-08-23

Coding system

ICD10 codes SNOMED CT codes

Collections

BHF Data Science Centre Phenotype Library

Definition

Code type is set to 1 for incident events, and 0 for prevalent events.

Publications

Association of COVID-19 vaccines ChAdOx1 and BNT162b2 with major venous, arterial, and thrombocytopenic events: whole population cohort study in 46 million adults in England CVD-COVID-UK consortium, William N Whiteley, Samantha Ip, Jennifer A Cooper, Thomas Bolton, Spencer Keene, Venexia Walker, Rachel Denholm, Ashley Akbari, Efosa Omigie, Sam Hollings, Emanuele Di Angelantonio, Spiros Denaxas, Angela Wood, Jonathan A C Sterne, Cathie Sudlow medRxiv 2021.08.18.21262222; doi: https://doi.org/10.1

Clinical Code List

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C2874/7395 CCU002_02 Depression - Phenotypes - England hospitalization EHR: Depression diagnosis - ICD10 codes

Rows: 2

Code	Description	terminology	code_type
F32	Depressive episode	ICD10	1.0
F33	Recurrent depressive disorder	ICD10	1.0

C2875/7396 CCU002_02 Depression - Phenotypes - England primary care EHR: Depression diagnosis - SNOMED CT codes

Rows: 67

Code	Description	terminology	code_type
1086471000000103	Recurrent reactive depressive episodes, severe, with psychosis (disorder)	SNOMEDCT	1.0
1086661000000108	Reactive depression, prolonged single episode (disorder)	SNOMEDCT	1.0
1089511000000100	Recurrent depression with current severe episode and psychotic features (disorder)	SNOMEDCT	1.0
1089631000000109	Recurrent depression with current severe episode without psychotic features (disorder)	SNOMEDCT	1.0
1089641000000100	Recurrent depression with current moderate episode (disorder)	SNOMEDCT	1.0
15639000	Moderate major depression, single episode (disorder)	SNOMEDCT	1.0
16264621000119109	Recurrent mild major depressive disorder co-occurrent with anxiety (disorder)	SNOMEDCT	1.0
16264901000119109	Recurrent moderate major depressive disorder co-occurrent with anxiety (disorder)	SNOMEDCT	1.0
16265951000119109	Mild major depressive disorder co-occurrent with anxiety single episode (disorder)	SNOMEDCT	1.0
16266831000119100	Moderate major depressive disorder co-occurrent with anxiety single episode (disorder)	SNOMEDCT	1.0
18818009	Moderate recurrent major depression (disorder)	SNOMEDCT	1.0
191455000	Presenile dementia with depression (disorder)	SNOMEDCT	1.0
191459006	Senile dementia with depression (disorder)	SNOMEDCT	1.0
191601008	Single major depressive episode, mild (disorder)	SNOMEDCT	1.0
191604000	Single major depressive episode, severe, with psychosis (disorder)	SNOMEDCT	1.0
191610000	Recurrent major depressive episodes, mild (disorder)	SNOMEDCT	1.0
191611001	Recurrent major depressive episodes, moderate (disorder)	SNOMEDCT	1.0
191613003	Recurrent major depressive episodes, severe, with psychosis (disorder)	SNOMEDCT	1.0
191616006	Recurrent depression (disorder)	SNOMEDCT	1.0
191659001	Atypical depressive disorder (disorder)	SNOMEDCT	1.0
191676002	Reactive depressive psychosis (disorder)	SNOMEDCT	1.0
192049004	Prolonged depressive adjustment reaction (disorder)	SNOMEDCT	1.0
192080009	Chronic depression (disorder)	SNOMEDCT	1.0
19527009	Single episode of major depression in full remission (disorder)	SNOMEDCT	1.0
231485007	Post-schizophrenic depression (disorder)	SNOMEDCT	1.0
231499006	Endogenous depression first episode (disorder)	SNOMEDCT	1.0
231500002	Masked depression (disorder)	SNOMEDCT	1.0
231504006	Mixed anxiety and depressive disorder (disorder)	SNOMEDCT	1.0
247803002	Seasonal affective disorder (disorder)	SNOMEDCT	1.0
251000119105	Severe major depression, single episode (disorder)	SNOMEDCT	1.0
25922000	Major depressive disorder, single episode with postpartum onset (disorder)	SNOMEDCT	1.0
268621008	Recurrent major depressive episodes (disorder)	SNOMEDCT	1.0
274948002	Endogenous depression - recurrent (disorder)	SNOMEDCT	1.0
28475009	Severe recurrent major depression with psychotic features (disorder)	SNOMEDCT	1.0
300706003	Endogenous depression (disorder)	SNOMEDCT	1.0
310495003	Mild depression (disorder)	SNOMEDCT	1.0
310496002	Moderate depression (disorder)	SNOMEDCT	1.0
310497006	Severe depression (disorder)	SNOMEDCT	1.0
35489007	Depressive disorder (disorder)	SNOMEDCT	1.0
357705009	Cotard's syndrome (disorder)	SNOMEDCT	1.0
36474008	Severe recurrent major depression without psychotic features (disorder)	SNOMEDCT	1.0
36923009	Major depression, single episode (disorder)	SNOMEDCT	1.0
370143000	Major depressive disorder (disorder)	SNOMEDCT	1.0
397701000000102	[X]Severe depressive episode without psychotic symptoms (disorder)	SNOMEDCT	1.0
397711000000100	[X]Severe depressive episode with psychotic symptoms (disorder)	SNOMEDCT	1.0
40379007	Mild recurrent major depression (disorder)	SNOMEDCT	1.0
40568001	Recurrent brief depressive disorder (disorder)	SNOMEDCT	1.0
430421000000104	[X]Mild depressive episode (disorder)	SNOMEDCT	1.0
465441000000108	[X]Moderate depressive episode (disorder)	SNOMEDCT	1.0
698957003	Depressive disorder in remission (disorder)	SNOMEDCT	1.0
70747007	Major depression single episode, in partial remission (disorder)	SNOMEDCT	1.0
720453001	Moderately severe major depression single episode (disorder)	SNOMEDCT	1.0
73867007	Severe major depression with psychotic features (disorder)	SNOMEDCT	1.0
75084000	Severe major depression without psychotic features (disorder)	SNOMEDCT	1.0
755321000000106	Single major depressive episode, severe, with psychosis, psychosis in remission (disorder)	SNOMEDCT	1.0
755331000000108	Recurrent major depressive episodes, severe, with psychosis, psychosis in remission (disorder)	SNOMEDCT	1.0
76441001	Severe major depression, single episode, without psychotic features (disorder)	SNOMEDCT	1.0
764611000000100	Recurrent major depressive episodes, severe (disorder)	SNOMEDCT	1.0
764691000000109	Recurrent major depressive episodes, in partial remission (disorder)	SNOMEDCT	1.0
765176007	Psychosis and severe depression co-occurrent and due to bipolar affective disorder (disorder)	SNOMEDCT	1.0
78667006	Dysthymia (disorder)	SNOMEDCT	1.0
79298009	Mild major depression, single episode (disorder)	SNOMEDCT	1.0
832007	Moderate major depression (disorder)	SNOMEDCT	1.0
83458005	Agitated depression (disorder)	SNOMEDCT	1.0
84760002	Schizoaffective disorder, depressive type (disorder)	SNOMEDCT	1.0
87414006	Reactive depression (situational) (disorder)	SNOMEDCT	1.0
87512008	Mild major depression (disorder)	SNOMEDCT	1.0

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH1005/version/2183/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH1005/version/2183/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH1005', '2183', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH1005/version/2183/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH1005/version/2183/export/codes/?format=json
CSV	site_root/phenotypes/PH1005/version/2183/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH1005', '2183', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
2183	CCU002_02 Depression	ieuan.scanlon	2022-05-17	currently shown
2089	CCU002_02 Depression	ieuan.scanlon	2022-05-09