Anxiety- Primary Care
John, A., Marchant, A. L., Fone, D. L., McGregor, J. I., Dennis, M. S., Tan, J. O. A., & Lloyd, K.Definition
These lists include diagnosis, symptoms and treatments of anxiety (e.g. chronic anxiety, generalized anxiety disorder), anxiety symptoms (e.g. anxiousness), mixed anxiety and depression, panic attacks and panic disorders. We included emotional disorders with onset usually in childhood (John et al., 2015), codes for phobias (Cornish et al., 2016) and obsessive compulsive disorders (John et al 2019; John et al., 2022) and PTSD (Moran et al., 2015) were also included. The algorithm encompassing a historical diagnosis which is currently being treated in combination with a current diagnosis which is treated or untreated improves sensitivity from using current diagnosis alone (John et al, 2016). This method was optimal for identifying common mental disorders in primary care.
Publications
Cornish, R. P., John, A., Boyd, A., Tilling, K., & Macleod, J. (2016). Defining adolescent common mental disorders using electronic primary care data: A comparison with outcomes measured using the CIS-R. BMJ Open, 6(12). https://doi.org/10.1136/bmjopen-2016-013167
John, A., Friedmann, Y., Delpozo-Banos, M., Frizzati, A., Ford, T., & Thapar, A. 2022. Association of School Absence and Exclusion with Recorded Neurodevelopmental Disorders, Mental Disorders, or Self-Harm: A Nationwide, Retrospective, Electronic Cohort Study of Children and Young People in Wales, UK.
John, A., Marchant, A. L., McGregor, J. I., Tan, J. O. A., Hutchings, H. A., Kovess, V., ... & Lloyd, K. (2015). Recent trends in the incidence of anxiety and prescription of anxiolytics and hypnotics in children and young people: an e-cohort study. Journal of affective disorders, 183, 134-141.
John, A., McGregor, J., Fone, D., Dunstan, F., Cornish, R.., Lyons, R A., & Lloyd, K R. (2016). Case-finding for common mental disorders of anxiety and depression in primary care: an external validation of routinely collected data, BMC Medical Informatics and Decision Making. https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-016-0274-7
John, A, Wood, S., Rees, S., Wang, T., & Marchant, A. (2019). Mental Healthcare in Young People and Young Adults. https://www.ncepod.org.uk/2019ypmh.html
Moran, G. M., Calvert, M., Feltham, M. G., Ryan, R., & Marshall, T. (2015). A retrospective cohort study to investigate fatigue, psychological or cognitive impairment after TIA: protocol paper. BMJ open, 5(4), e008149.
Clinical Code List
C2921/7702
Anxiety - Diagnosis - Primary Care 
- Read codes v2
| Code | Description |
|---|---|
| E200. | anxiety states |
| E2000 | anxiety state unspecified |
| E2001 | panic disorder |
| E2002 | generalised anxiety disorder |
| E2004 | chronic anxiety |
| E2005 | recurrent anxiety |
| E200z | anxiety state nos |
| E202. | phobic disorders |
| E2020 | phobia unspecified |
| E2021 | agoraphobia with panic attacks |
| E2022 | agoraphobia - no panic attacks | agoraphobia without mention of panic attacks |
| E2023 | social phobia-eating in public | social phobia, fear of eating in public |
| E2024 | social phobia-public speaking | social phobia, fear of public speaking |
| E2025 | social phobia-public washing | social phobia, fear of public washing |
| E2026 | acrophobia |
| E2027 | animal phobia |
| E2028 | claustrophobia |
| E2029 | fear of crowds |
| E202A | fear of flying |
| E202B | cancer phobia |
| E202C | dental phobia |
| E202D | fear of death |
| E202E | fear of pregnancy |
| E202z | phobic disorder nos |
| E203. | obsessive-compulsive disorders |
| E2030 | compulsive neurosis |
| E2031 | obsessional neurosis |
| E203z | obsessive-compulsive dis nos | obsessive-compulsive disorder nos |
| E28z. | acute stress reaction nos |
| E2920 | separation anxiety disorder |
| Eu40. | [x]phobic anxiety disorders |
| Eu400 | [x]agoraphobia |
| Eu401 | [x]social phobias |
| Eu402 | [x]specific (isolated) phobia | [x]specific (isolated) phobias |
| Eu403 | [x]needle phobia |
| Eu40y | [x]other phobic anxiety disord | [x]other phobic anxiety disorders |
| Eu40z | [x]phobic anxiety disordr unsp | [x]phobic anxiety disorder, unspecified |
| Eu41. | [x]other anxiety disorders |
| Eu410 | [x]panic episodic paroxysm anx | [x]panic disorder [episodic paroxysmal anxiety] |
| Eu411 | [x]generalized anxiety disord | [x]generalized anxiety disorder |
| Eu413 | [x]other mixed anxiety disord | [x]other mixed anxiety disorders |
| Eu41y | [x]other specif anxiety disord | [x]other specified anxiety disorders |
| Eu41z | [x]anxiety disord unspecified | [x]anxiety disorder, unspecified |
| Eu42. | [x]obsessive - compulsive dis | [x]obsessive - compulsive disorder |
| Eu420 | [x]predom obsessional thoughts | [x]predominantly obsessional thoughts or ruminations |
| Eu421 | [x]predom compuls acts/ritual | [x]predominantly compulsive acts [obsessional rituals] |
| Eu422 | [x]mixed obsess thoughts/acts | [x]mixed obsessional thoughts and acts |
| Eu42y | [x]oth obsessve-compulsve dis | [x]other obsessive-compulsive disorders |
| Eu42z | [x]obsessve-complsve dis unsp | [x]obsessive-compulsive disorder, unspecified |
C2922/7703
Anxiety- Diagnosis (CYP)- Primary Care
- Read codes v2
| Code | Description |
|---|---|
| E2D0. | anxiety/fear child/adoles.dis. | disturbance of anxiety and fearfulness childhood/adolescent | disturbance of anxiety and fearfulness in childhood and adolescence |
| E2D00 | child/adolesc.overanxious.dis. | childhood and adolescent overanxiousness disturbance |
| E2D01 | child/adolesc.fearfulness dis. | childhood and adolescent fearfulness disturbance |
| E2D0z | anxiety/fear child/adolesc.nos | disturbance anxiety and fearfulness childhood/adolescent nos | disturbance of anxiety and fearfulness in childhood and adolescence nos |
| Eu930 | [x]separ anxiety dis childhood | [x]separation anxiety disorder of childhood |
| Eu931 | [x]phobic anxiet dis childhood | [x]phobic anxiety disorder of childhood |
| Eu932 | [x]social anx dis childhood | [x]social anxiety disorder of childhood |
C2923/7704
Anxiety- Symptoms- Primary Care
- Read codes v2
| Code | Description |
|---|---|
| 1B12. | nerves - nervousness |
| 1B13. | anxiousness |
| 1B1V. | c/o - panic attack |
| 2258 | o/e - anxious |
| 2259 | o/e - nervous |
| 225J. | o/e - panic attack |
| R2y2. | [d]nervousness |
C2924/7710
Anxiety- Prescriptions (Anxiolytics)- Primary Care
- Read codes v2
| Code | Description |
|---|---|
| d2... | anxiolytics |
| d21.. | diazepam [anxiolytic] |
| d211. | *diazepam 2mg capsules |
| d212. | *diazepam 5mg capsules |
| d213. | diazepam 2mg tablets |
| d214. | diazepam 5mg tablets |
| d215. | diazepam 10mg tablets |
| d216. | diazepam 2mg/5ml elixir |
| d217. | *alupram 2mg tablets |
| d218. | *alupram 5mg tablets |
| d219. | *alupram 10mg tablets |
| d21A. | diazepam 5mg/5ml oral solution |
| d21B. | *rimapam 2mg tablets |
| d21C. | *rimapam 5mg tablets |
| d21D. | *rimapam 10mg tablets |
| d21E. | dialar 2mg/5ml syrup |
| d21F. | dialar 5mg/5ml syrup |
| d21G. | *valclair 10mg suppositories |
| d21J. | diazepam 10mg/5ml suspension |
| d21a. | *atensine 2mg tablets |
| d21b. | *atensine 5mg tablets |
| d21c. | *atensine 10mg tablets |
| d21d. | diazemuls 10mg/2ml ampoules |
| d21e. | *evacalm 2mg tablets |
| d21f. | *evacalm 5mg tablets |
| d21g. | *solis 2mg capsules |
| d21h. | *solis 5mg capsules |
| d21i. | *stesolid 10mg/2ml injection |
| d21j. | *stesolid 20mg/4ml injection |
| d21k. | stesolid 5mg rectal solution |
| d21l. | stesolid 10mg rectal solution |
| d21m. | tensium 2mg tablets |
| d21n. | tensium 5mg tablets |
| d21o. | tensium 10mg tablets |
| d21p. | *valium 2mg capsules |
| d21q. | *valium 5mg capsules |
| d21r. | *valium 2mg tablets |
| d21s. | *valium 5mg tablets |
| d21t. | *valium 10mg tablets |
| d21u. | *valium 2mg/5ml syrup |
| d21v. | valium [anxiol] 10mg/2ml inj | valium [anxiol] 10mg/2ml injection |
| d21w. | *valium dup del injection |
| d21x. | *valium 5mg suppositories |
| d21y. | *valium 10mg suppositories |
| d21z. | *diazepam 10mg suppositories |
| d22.. | alprazolam |
| d221. | xanax 250micrograms tablets |
| d222. | xanax 500micrograms tablets |
| d22y. | alprazolam 250mcg tablets | alprazolam 250microgram tablets |
| d22z. | alprazolam 500mcg tablets | alprazolam 500microgram tablets |
| d23.. | bromazepam |
| d231. | *lexotan 1.5mg tablets |
| d232. | *lexotan 3mg tablets |
| d23y. | *bromazepam 1.5mg tablets |
| d23z. | *bromazepam 3mg tablets |
| d24.. | chlordiazepoxide |
| d241. | chlordiazepoxide 5mg capsules |
| d242. | chlordiazepoxide 10mg capsules |
| d243. | chlordiazepoxide hcl 5mg tabs | chlordiazepoxide hydrochloride 5mg tablets |
| d244. | chlordiazepoxide hcl 10mg tabs | chlordiazepoxide hydrochloride 10mg tablets |
| d245. | *chlordiazepoxide hcl 25mg tab | chlordiazepoxide hydrochloride 25mg tablets |
| d246. | *chlordiazepoxide 5mg tablets |
| d247. | *chlordiazepoxide 10mg tablets |
| d248. | *chlordiazepoxide 25mg tablets |
| d249. | librium 5mg capsules |
| d24a. | librium 10mg capsules |
| d24b. | *librium 5mg tablets |
| d24c. | *librium 10mg tablets |
| d24d. | *librium 25mg tablets |
| d24e. | *librium 100mg injection |
| d24f. | tropium 5mg capsules |
| d24g. | *tropium 10mg capsules |
| d24h. | tropium 5mg tablets |
| d24i. | tropium 10mg tablets |
| d24j. | *tropium 25mg tablets |
| d25.. | chlormezanone |
| d251. | *trancopal 200mg tablets |
| d25z. | *chlormezanone 200mg tablets |
| d26.. | clobazam |
| d261. | *clobazam 10mg capsules |
| d262. | *frisium 10mg capsules |
| d263. | clobazam 10mg tablets |
| d264. | frisium 10mg tablets |
| d265. | tapclob 5mg/5ml oral susp | tapclob 5mg/5ml oral suspension |
| d266. | clobazam 5mg/5ml oral susp | clobazam 5mg/5ml oral suspension |
| d267. | tapclob 10mg/5ml oral susp | tapclob 10mg/5ml oral suspension |
| d268. | clobazam 10mg/5ml oral susp | clobazam 10mg/5ml oral suspension |
| d269. | perizam 1mg/ml oral suspension |
| d26A. | perizam 2mg/ml oral suspension |
| d27.. | clorazepate dipotassium |
| d271. | *tranxene 7.5mg capsules |
| d272. | *tranxene 15mg capsules |
| d27y. | *clorazepate 7.5mg capsules | clorazepate dipotassium 7.5mg capsules |
| d27z. | *clorazepate 15mg capsules | clorazepate dipotassium 15mg capsules |
| d28.. | hydroxyzine hcl [anxiolytic] |
| d281. | atarax 10mg tablets |
| d282. | atarax 25mg tablets |
| d283. | *atarax 10mg/5ml syrup |
| d284. | ucerax 25mg tablets |
| d285. | ucerax 10mg/5ml syrup |
| d28x. | hydroxyzine hcl 10mg tablets |
| d28y. | hydroxyzine hcl 25mg tablets |
| d28z. | hydroxyzine hcl 10mg/5ml syrup |
| d29.. | *ketazolam |
| d291. | *anxon 15mg capsules |
| d292. | *anxon 30mg capsules |
| d29y. | *ketazolam 15mg capsules |
| d29z. | *ketazolam 30mg capsules |
| d2a.. | lorazepam [anxiolytic] |
| d2a1. | lorazepam 1mg tablets |
| d2a2. | lorazepam 2.5mg tablets |
| d2a3. | *almazine 1mg tablets |
| d2a4. | *almazine 2.5mg tablets |
| d2a5. | *ativan 1mg tablets |
| d2a6. | *ativan 2.5mg tablets |
| d2a7. | ativan 4mg/1ml injection |
| d2ax. | *ativan 4mg/ml injection |
| d2az. | lorazepam 4mg/1ml injection |
| d2b.. | *medazepam |
| d2b1. | *nobrium 5mg capsules |
| d2b2. | *nobrium 10mg capsules |
| d2by. | *medazepam 5mg capsules |
| d2bz. | *medazepam 10mg capsules |
| d2c.. | meprobamate |
| d2c1. | *meprobamate 200mg tablets |
| d2c2. | meprobamate 400mg tablets |
| d2c3. | *equanil 200mg tablets |
| d2c4. | *equanil 400mg tablets |
| d2c5. | meprate 400mg tablets |
| d2c6. | *tenavoid tablets |
| d2d.. | oxazepam |
| d2d1. | *oxazepam 30mg capsules |
| d2d2. | oxazepam 10mg tablets |
| d2d3. | oxazepam 15mg tablets |
| d2d4. | oxazepam 30mg tablets |
| d2d5. | *oxanid 10mg tablets |
| d2d6. | *oxanid 15mg tablets |
| d2d7. | *oxanid 30mg tablets |
| d2e.. | *prazepam |
| d2e1. | *centrax 10mg tablets |
| d2ez. | *prazepam 10mg tablets |
| d2f.. | buspirone hydrochloride |
| d2f1. | buspirone 5mg tablets |
| d2f2. | *buspar 5mg tablets |
| d2f3. | *buspar 5mg tablets x126 |
| d2f4. | *buspar 10mg tablets |
| d2f5. | buspirone 10mg tablets |
| d2g.. | flumazenil |
| d2g1. | flumazenil 500mcg/5ml inj | flumazenil 500microgram/5ml injection |
| d2g2. | anexate 500mcg/5ml injection | anexate 500micrograms/5ml injection |
C2925/7711
Anxiety- Prescriptions (Hypnotics)- Primary Care
- Read codes v2
| Code | Description |
|---|---|
| d1... | hypnotics |
| d11.. | chloral hydrate |
| d111. | *chloral 500mg/5ml mixture |
| d112. | *chloral paed 200mg/5ml elixir | chloral paediatric 200mg/5ml elixir |
| d113. | *noctec 500mg capsules |
| d114. | *chloral hydrate 500mg caps | chloral hydrate 500mg capsules |
| d115. | welldorm 143mg/5ml elixir |
| d116. | welldorm tablets |
| d117. | chloral hydrate 414mg tablets |
| d118. | chloral hydrate 143mg/5ml elix | chloral hydrate 143mg/5ml elixir |
| d119. | chloral hydrate 500mg/5ml syr | chloral hydrate 500mg/5ml syrup |
| d11A. | somnwell 707mg tablets |
| d12.. | clomethiazole ed. [hypnot] | clomethiazole edisylate [hypnotic] |
| d121. | *heminevrin 192mg capsules |
| d122. | *heminevrin 250mg/5ml syrup |
| d123. | *heminevrin 8mg/ml infusion |
| d12v. | clomethiazole(base) 192mg caps | clomethiazole(base) 192mg capsules |
| d12w. | clomethiaz edis 250mg/5ml syrp | clomethiazole edisilate 250mg/5ml syrup |
| d12z. | *chlormethiazole 8mg/ml inf | chlormethiazole edisylate 8mg/ml infusion |
| d13.. | *dichloralphenazone |
| d131. | *welldorm 650mg tablets |
| d132. | *welldorm 225mg/5ml elixir |
| d13y. | *dichloralphenazone 650mg tabs | dichloralphenazone 650mg tablets |
| d13z. | *dichloralphenazone 225mg/5ml | dichloralphenazone 225mg/5ml elixir |
| d14.. | *flunitrazepam |
| d141. | *rohypnol 1mg tablets |
| d14z. | *flunitrazepam 1mg tablets |
| d15.. | flurazepam |
| d151. | dalmane 15mg capsules |
| d152. | dalmane 30mg capsules |
| d153. | *paxane 15mg capsules |
| d154. | *paxane 30mg capsules |
| d15y. | flurazepam 15mg capsules |
| d15z. | flurazepam 30mg capsules |
| d16.. | loprazolam |
| d161. | loprazolam 1mg tablets |
| d162. | *dormonoct 1mg tablets |
| d17.. | lormetazepam |
| d171. | lormetazepam 500mcg tablets | lormetazepam 500micrograms tablets |
| d172. | lormetazepam 1mg tablets |
| d173. | *noctamid 500mcg tablets | noctamid 500micrograms tablets |
| d174. | *noctamid 1mg tablets |
| d18.. | nitrazepam |
| d181. | *nitrazepam 5mg capsules |
| d182. | nitrazepam 5mg tablets |
| d183. | *nitrazepam 10mg tablets |
| d184. | nitrazepam 2.5mg/5ml mixture |
| d185. | *mogadon 5mg capsules |
| d186. | mogadon 5mg tablets |
| d187. | *nitrados 5mg tablets |
| d188. | *noctesed 5mg tablets |
| d189. | remnos 5mg tablets |
| d18a. | *remnos 10mg tablets |
| d18b. | *somnite 5mg tablets |
| d18c. | somnite 2.5mg/5ml mixture |
| d18d. | *surem 5mg capsules |
| d18e. | *unisomnia 5mg tablets |
| d18f. | nitrazepam 5mg/5ml suspension |
| d1a.. | temazepam [hypnotic] |
| d1a1. | *temazepam 10mg capsules |
| d1a2. | *temazepam 15mg capsules |
| d1a3. | *temazepam 20mg capsules |
| d1a4. | *temazepam 30mg capsules |
| d1a5. | *temazepam 10mg/5ml elixir |
| d1a6. | *normison 10mg capsules |
| d1a7. | *normison 20mg capsules |
| d1a8. | *temazepam planpak capsules |
| d1a9. | temazepam 10mg tablets |
| d1aa. | temazepam 20mg tablets |
| d1ab. | *temazepam gelthix 10mg caps | temazepam gelthix 10mg capsules |
| d1ac. | *temazepam gelthix 20mg caps | temazepam gelthix 20mg capsules |
| d1ad. | *temazepam gelthix 15mg caps | temazepam gelthix 15mg capsules |
| d1ae. | *temazepam gelthix 30mg caps | temazepam gelthix 30mg capsules |
| d1af. | *temazepam gel filled 10mg cap | temazepam gel filled 10mg capsules |
| d1ag. | *temazepam gel filled 20mg cap | temazepam gel filled 20mg capsules |
| d1ah. | *temazepam gel filled 15mg cap | temazepam gel filled 15mg capsules |
| d1ai. | *temazepam gel filled 30mg cap | temazepam gel filled 30mg capsules |
| d1aj. | *temazepam 10mg/sachet soln | temazepam 10mg/sachet oral solution |
| d1ak. | *temazepam 20mg/sach oral soln | temazepam 20mg/sachet oral solution |
| d1al. | *euhypnos 10mg/sachet solution | euhypnos 10mg/sachet oral solution |
| d1am. | *euhypnos 20mg/sachet solution | euhypnos 20mg/sachet oral solution |
| d1an. | *euhypnos 10mg/5ml oral soln | euhypnos 10mg/5ml oral solution |
| d1ao. | temazepam 10mg/5ml s/f soln | temazepam 10mg/5ml sugar free oral solution |
| d1b.. | *triazolam |
| d1b1. | *triazolam 125mcg tablets | triazolam 125microgram tablets |
| d1b2. | *triazolam 250mcg tablets | triazolam 250microgram tablets |
| d1b3. | *halcion 125microgram tablets |
| d1b4. | *halcion 250microgram tablets |
| d1c.. | triclofos sodium |
| d1c1. | *triclofos 500mg/5ml liquid |
| d1d.. | zopiclone |
| d1d1. | zopiclone 7.5mg tablets |
| d1d2. | zimovane 7.5mg tablets |
| d1d3. | zopiclone 3.75mg tablets |
| d1d4. | zimovane ls 3.75mg tablets |
| d1d5. | *zileze 7.5 tablets |
| d1d6. | *zileze 3.75 tablets |
| d1f.. | zolpidem |
| d1f1. | stilnoct 5mg tablets |
| d1f2. | zolpidem tartrate 5mg tablets |
| d1f3. | zolpidem tartrate 10mg tablets |
| d1f4. | stilnoct 10mg tablets |
| d1g.. | zaleplon |
| d1g1. | sonata 5mg capsules |
| d1g2. | sonata 10mg capsules |
| d1gy. | zaleplon 5mg capsules |
| d1gz. | zaleplon 10mg capsules |
| d1h.. | melatonin |
| d1h1. | circadin 2mg m/r tablets |
| d1hz. | melatonin 2mg m/r tablets |
| d1i.. | dexmedetomidine |
| d1i1. | dexdor 200mcg/2ml conc for inf | dexdor 200micrograms/2ml concentrate for soln for infusion |
| d1i2. | dexmedetomidine 200mcg/2ml inj | dexmedetomidine 200micrograms/2ml conc for soln for inj |
| d1i3. | dexdor 400mcg/4ml conc for inf | dexdor 400micrograms/4ml concentrate for soln for infusion |
| d1i4. | dexmedetomidine 400mcg/4ml inj | dexmedetomidine 400micrograms/4ml conc for soln for inj |
| d1i5. | dexdor 1mg/10ml conc for inf | dexdor 1mg/10ml concentrate for solution for infusion |
| d1i6. | dexmedetomidine 1mg/10ml inj | dexmedetomidine 1mg/10ml concentrate for soln for injection |
C2949/7683
Anxiety - Therapeutic Procedures - Primary Care
- Read codes v2
| Code | Description |
|---|---|
| 8G52. | antiphobic therapy |
| 8G94. | anxiety management training |
| 8HHp. | ref guid self-help for anxiety | referral for guided self-help for anxiety |
API
To Export Phenotype Details:
| Format | API |
|---|---|
| XML | site_root/api/v1/public/phenotypes/PH1022/version/2203/detail/?format=xml |
| JSON | site_root/api/v1/public/phenotypes/PH1022/version/2203/detail/?format=json |
| R Package |
|
To Export Phenotype Code List:
| Format | API |
|---|---|
| XML | site_root/api/v1/public/phenotypes/PH1022/version/2203/export/codes/?format=xml |
| JSON | site_root/api/v1/public/phenotypes/PH1022/version/2203/export/codes/?format=json |
| CSV | site_root/phenotypes/PH1022/version/2203/export/codes/ |
| R Package |
|
Version History
| Version ID |
Name | Owner | Publish date | |
|---|---|---|---|---|
| 2203 | Anxiety- Primary Care | zinnurar | 2022-07-05 | currently shown |
Export - export all codes into a csv file/JSON/XML for the current phenotype version.
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