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Acute Myocardial Infarction (AMI)

Julie George, Emily Herrett, Liam Smeeth, Harry Hemingway, Anoop Shah, Spiros Denaxas

ID
PH1024
Version ID
2257
Type
Disease or Syndrome
Data Sources
Valid event data range
01/01/1999 - 01/07/2016
Sex
♀  Female ♂  Male
Agreement Date
None
Coding system
Read codes v2 ICD10 codes OPCS4 codes ICD9 codes
Collections
CALIBER
Tags
No tags

Definition

Combining evidence across sources to define and date phenotypes

If there are records of non-ST elevation MI and ST elevation MI on the same date, the more severe diagnosis (STEMI) is taken as correct. If there is a record of unspecified MI and STEMI / NSTEMI on the same date, the non-specific diagnosis is ignored. MI may be recorded multiple times in the different datasets with slightly different dates. It is up to the researcher to decide what time interval should be used as a cut-off for considering that two events close to each other are distinct events rather than multuiple records of the same event; we would suggest 7 days because this is just greater than the usual duration of hospitalization for myocardial infarction.

Publications

  • Steele AJ et al. Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease. PLoS One. 2018 Aug 31;13(8):e0202344. doi: 10.1371/journal.pone.0202344. eCollection 2018. PMID: 30169498

  • Archangelidi O et al. Clinically recorded heart rate and incidence of 12 coronary, cardiac, cerebrovascular and peripheral arterial diseases in 233,970 men and women: A linked electronic health record study. Eur J Prev Cardiol. 2018 Sep;25(14):1485-1495. doi: 10.1177/2047487318785228. Epub 2018 Jul 2. PMID: 29966429

  • Koudstaal S et al. Prognostic burden of heart failure recorded in primary care, acute hospital admissions, or both: a population-based linked electronic health record cohort study in 2.1 million people. Eur J Heart Fail. 2017 Sep;19(9):1119-1127. doi: 10.1002/ejhf.709. Epub 2016 Dec 23. PMID: 28008698

  • Chung SC et al. Time spent at blood pressure target and the risk of death and cardiovascular diseases. PLoS One. 2018 Sep 5;13(9):e0202359. doi: 10.1371/journal.pone.0202359. eCollection 2018. PMID: 30183734

  • Bell S et al. Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records. BMJ. 2017 Mar 22;356:j909. PMID: 28331015

  • Pasea L et al. Personalising the decision for prolonged dual antiplatelet therapy: development, validation and potential impact of prognostic models for cardiovascular events and bleeding in myocardial infarction survivors. Eur Heart J. 2017 Apr 7;38(14):1048-1055. doi: 10.1093/eurheartj/ehw683. PMID: 28329300

  • Shah AD et al. Neutrophil Counts and Initial Presentation of 12 Cardiovascular Diseases: A CALIBER Cohort Study. J Am Coll Cardiol. 2017 Mar 7;69(9):1160-1169. doi: 10.1016/j.jacc.2016.12.022. PMID: 28254179

  • Asaria M et al. Using electronic health records to predict costs and outcomes in stable coronary artery disease. Heart. 2016 May 15;102(10):755-62. doi: 10.1136/heartjnl-2015-308850. Epub 2016 Feb 10. PMID: 26864674

  • Daskalopoulou M et al. Depression as a Risk Factor for the Initial Presentation of Twelve Cardiac, Cerebrovascular, and Peripheral Arterial Diseases: Data Linkage Study of 1.9 Million Women and Men. PLoS One. 2016 Apr 22;11(4):e0153838. doi: 10.1371/journal.pone.0153838. eCollection 2016. PMID: 27105076

  • Pujades-Rodriguez M et al. Associations between polymyalgia rheumatica and giant cell arteritis and 12 cardiovascular diseases. Heart. 2016 Mar;102(5):383-9. doi: 10.1136/heartjnl-2015-308514. Epub 2016 Jan 19. PMID: 26786818

  • Pujades-Rodriguez M et al. Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A Population Record-Linkage Cohort Study in England. PLoS One. 2016 Mar 15;11(3):e0151245. doi: 10.1371/journal.pone.0151245. eCollection 2016. PMID: 26978266

  • Shah AD et al. Low eosinophil and low lymphocyte counts and the incidence of 12 cardiovascular diseases: a CALIBER cohort study. Open Heart. 2016 Sep 5;3(2):e000477. doi: 10.1136/openhrt-2016-000477. eCollection 2016. PMID: 27621833

  • Timmis A et al. Prolonged dual antiplatelet therapy in stable coronary disease: comparative observational study of benefits and harms in unselected versus trial populations. BMJ. 2016 Jun 22;353:i3163. PMID: 27334486

  • Walker S et al. Long-term healthcare use and costs in patients with stable coronary artery disease: a population-based cohort using linked health records (CALIBER). Eur Heart J Qual Care Clin Outcomes. 2016 Jan 20;2(2):125-140. doi: 10.1093/ehjqcco/qcw003. PMID: 27042338

  • George J et al. How Does Cardiovascular Disease First Present in Women and Men? Incidence of 12 Cardiovascular Diseases in a Contemporary Cohort of 1,937,360 People. Circulation. 2015 Oct 6;132(14):1320-8. doi: 10.1161/CIRCULATIONAHA.114.013797. Epub 2015 Sep 1. PMID: 26330414

  • Morley KI et al. Defining disease phenotypes using national linked electronic health records: a case study of atrial fibrillation. PLoS One. 2014 Nov 4;9(11):e110900. doi: 10.1371/journal.pone.0110900. eCollection 2014. PMID: 25369203

  • Pujades-Rodriguez M et al. Heterogeneous associations between smoking and a wide range of initial presentations of cardiovascular disease in 1937360 people in England: lifetime risks and implications for risk prediction. Int J Epidemiol. 2015 Feb;44(1):129-41. doi: 10.1093/ije/dyu218. Epub 2014 Nov 20. PMID: 25416721

  • Pujades-Rodriguez M et al. Socioeconomic deprivation and the incidence of 12 cardiovascular diseases in 1.9 million women and men: implications for risk prediction and prevention. PLoS One. 2014 Aug 21;9(8):e104671. doi: 10.1371/journal.pone.0104671. eCollection 2014. PMID: 25144739

  • Rapsomaniki E et al. Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1.25 million people. Lancet. 2014 May 31;383(9932):1899-911. doi: 10.1016/S0140-6736(14)60685-1. PMID: 24881994

  • Shah AD et al. Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1.9 million people. Lancet Diabetes Endocrinol. 2015 Feb;3(2):105-13. doi: 10.1016/S2213-8587(14)70219-0. Epub 2014 Nov 11. PMID: 25466521

  • Rapsomaniki E et al. Prognostic models for stable coronary artery disease based on electronic health record cohort of 102 023 patients. Eur Heart J. 2014 Apr;35(13):844-52. doi: 10.1093/eurheartj/eht533. Epub 2013 Dec 17. PMID: 24353280

Clinical Code List

Rows: 43
Code Description CALIBER.Category
323..00 ECG: myocardial infarction Acute MI not further specified
3233 ECG: antero-septal infarct. Acute MI not further specified
3234 ECG:posterior/inferior infarct Acute MI not further specified
3235 ECG: subendocardial infarct Acute MI not further specified
3236 ECG: lateral infarction Acute MI not further specified
323Z.00 ECG: myocardial infarct NOS Acute MI not further specified
889A.00 Diab mellit insulin-glucose infus acute myocardial infarct Acute MI not further specified
G30..00 Acute myocardial infarction Acute MI not further specified
G30..12 Coronary thrombosis Acute MI not further specified
G30..13 Cardiac rupture following myocardial infarction (MI) Acute MI not further specified
G30..15 MI - acute myocardial infarction Acute MI not further specified
G30..16 Thrombosis - coronary Acute MI not further specified
G300.00 Acute anterolateral infarction Acute MI not further specified
G301.00 Other specified anterior myocardial infarction Acute MI not further specified
G301000 Acute anteroapical infarction Acute MI not further specified
G301100 Acute anteroseptal infarction Acute MI not further specified
G301z00 Anterior myocardial infarction NOS Acute MI not further specified
G302.00 Acute inferolateral infarction Acute MI not further specified
G303.00 Acute inferoposterior infarction Acute MI not further specified
G304.00 Posterior myocardial infarction NOS Acute MI not further specified
G305.00 Lateral myocardial infarction NOS Acute MI not further specified
G306.00 True posterior myocardial infarction Acute MI not further specified
G307.00 Acute subendocardial infarction Acute MI not further specified
G307000 Acute non-Q wave infarction Acute MI not further specified
G307100 Acute non-ST segment elevation myocardial infarction NSTEMI
G308.00 Inferior myocardial infarction NOS Acute MI not further specified
G309.00 Acute Q-wave infarct Acute MI not further specified
G30B.00 Acute posterolateral myocardial infarction Acute MI not further specified
G30X.00 Acute transmural myocardial infarction of unspecif site Acute MI not further specified
G30X000 Acute ST segment elevation myocardial infarction STEMI
G30y.00 Other acute myocardial infarction Acute MI not further specified
G30y000 Acute atrial infarction Acute MI not further specified
G30y100 Acute papillary muscle infarction Acute MI not further specified
G30y200 Acute septal infarction Acute MI not further specified
G30yz00 Other acute myocardial infarction NOS Acute MI not further specified
G30z.00 Acute myocardial infarction NOS Acute MI not further specified
G31y100 Microinfarction of heart Acute MI not further specified
G38..00 Postoperative myocardial infarction Acute MI not further specified
G380.00 Postoperative transmural myocardial infarction anterior wall Acute MI not further specified
G381.00 Postoperative transmural myocardial infarction inferior wall Acute MI not further specified
G384.00 Postoperative subendocardial myocardial infarction Acute MI not further specified
G38z.00 Postoperative myocardial infarction, unspecified Acute MI not further specified
Gyu3400 [X]Acute transmural myocardial infarction of unspecif site Acute MI not further specified
Rows: 1
Code Description CALIBER.Category
I21 Acute myocardial infarction Acute MI not further specified
Rows: 2
Code Description CALIBER.Category
K50.2 Percutaneous transluminal coronary thrombolysis using streptokinase Transluminal coronary thrombolysis
K50.3 Percutaneous transluminal injection of therapeutic substance into coronary artery NEC Transluminal coronary thrombolysis
Rows: 3
Code Description category
410 Acute myocardial infarction Myocardial infarction
4110 Other acute and subacute forms of ischemic heart disease ; Postmyocardial infarction syndrome Myocardial infarction
4297 Ill-defined descriptions and complications of heart disease ; Certain sequelae of myocardial infarction, not elsewhere classified Myocardial infarction
Rows: 3
Code Description category
I21 Acute myocardial infarction Myocardial Infarction
I22 Subsequent myocardial infarction Myocardial Infarction
I23 Certain current complications following acute myocardial infarction Myocardial Infarction

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH1024/version/2257/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH1024/version/2257/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH1024', '2257', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH1024/version/2257/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH1024/version/2257/export/codes/?format=json
CSV site_root/phenotypes/PH1024/version/2257/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH1024', '2257', api_client=client)

Version History

Version
ID
Name Owner Publish date
2257 Acute Myocardial Infarction (AMI) ieuan.scanlon 2022-08-23 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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