Print

COPD

Eleanor L Axson, Jennifer K Quint

Type
Disease or Syndrome
ID
PH11
Version ID
22
Valid event data range
01/01/2001 - 31/12/2019
Sex
Female, Male
Agreement Date
2020-06-03
Coding system
Read codes v2 ICD10 codes UKBioBank codes ICD11 codes SNOMED CT codes
Tags /Collections
BREATHE Phenotype Library

Definition

These codes are not intended to be mandatory, but are to be used as a starting point for the identification of COPD in routine EHR. Each study may differ in the sensitivity and specificity of the coding required.

According to the National Institute for Health and Care Excellence (NICE) guidelines for the diagnosis of COPD, COPD should be suspected in patients over 35 years old who have a risk factor (typically smoking) and at least one symptom. It is therefore recommended that these codes are only utilised in an adult population at least 35 years old with a history of smoking.

https://www.nice.org.uk/guidance/ng115/chapter/Recommendations#diagnosing-copd

Validation of Read Codes for the Identification of COPD in CPRD

"Quint et al. validated a set of Read codes for the identification of COPD in CPRD in 2014. Using diagnostic codes alone, the positive predictive value (PPV) was 86.5% (77.5?92.3%). Requiring a diagnostic code, spirometry measures, and specific medication increased PPV to 89.4% (80.7?94.5%) but reduced case numbers by 10%."

Implementation


Publications

  • Publications in 2019 using validated Read codes from Quint et al. 2014

  • D. Stolz, Kostikas, K., Loefroth, E., Fogel, R., Gutzwiller, F. S., Conti, V., Cao, H., and Clemens, A., ?Differences in COPD exacerbation risk between women and men: analysis from the UK Clinical Practice Research Datalink data?, Chest, 2019."

  • M. Pikoula, Quint, J. K., Nissen, F., Hemingway, H., Smeeth, L., and Denaxas, S., ?Identifying clinically important COPD sub-types using data-driven approaches in primary care population based electronic health records?, BMC Med Inform Decis Mak, vol. 19, p. 86, 2019."

  • H. R. Whittaker, Mullerova, H., Jarvis, D., Barnes, N. C., Jones, P. W., Compton, C. H., Kiddle, S. J., and Quint, J. K., ?Inhaled corticosteroids, blood eosinophils, and FEV1 decline in patients with COPD in a large UK primary health care setting?, Int J Chron Obstruct Pulmon Dis, vol. 14, pp. 1063-1073, 2019."

  • C. I. Bloom, Ricciardi, F., Smeeth, L., Stone, P., and Quint, J. K., ?Predicting COPD 1-year mortality using prognostic predictors routinely measured in primary care?, BMC Med, vol. 17, p. 73, 2019."

  • D. Dedman, Coton, S. J., Ghosh, R. E., Meeraus, W., Crim, C., Harvey, C., Amelio, J., and Landis, S. H., ?Treatment Patterns of New Users of Fluticasone Furoate/Vilanterol in Asthma and COPD in UK Primary Care: Retrospective Cohort Study?, Pulmonary Therapy, vol. 5, pp. 81-95, 2019."

  • J. D. Chalmers, Poole, C., Webster, S., Tebboth, A., Dickinson, S., and Gayle, A., ?Assessing the healthcare resource use associated with inappropriate prescribing of inhaled corticosteroids for people with chronic obstructive pulmonary disease (COPD) in GOLD groups A or B: an observational study using the Clinical Practice Research Data?, Respir Res, vol. 19, p. 63, 2018."

  • Publications in 2019 using Read codes from QOF

  • P. Rockenschaub, Jhass, A., Freemantle, N., Aryee, A., Rafiq, M., Hayward, A., and Shallcross, L., ?Opportunities to reduce antibiotic prescribing for patients with COPD in primary care: a cohort study using electronic health records from the Clinical Practice Research Datalink (CPRD)?, J Antimicrob Chemother, 2019."

Clinical Code List

Rows: 88
Code Description SNOMED CT Description ID SNOMED CT Concept ID Validated Read Codes Quint et al. 2014 Quality and Outcomes Framework Read Codes 2017/18
14B3.12 History of chronic obstructive pulmonary disease 1765681000000110 270473001
14OX.00 At risk of chronic obstructive pulmonary diseas exacerbation 756761000000112 383611000000102
663K.00 Airways obstructn irreversible 1489743015 170628003 Y
66YB.00 Chronic obstructive pulmonary disease monitoring 1484924013 390891009 Y
66YB000 Chronic obstructive pulmonary disease 3 monthly review 1683181000000112 760601000000107
66YB100 Chronic obstructive pulmonary disease 6 monthly review 1683221000000119 760621000000103
66YB200 Telehealth chronic obstructive pulmonary disease monitoring 3305683010 716358000
66YD.00 Chronic obstructive pulmonary disease monitoring due 1484971019 390941006 Y
66YI.00 Chronic obstructive pulmonary disease self-management plan given 1484924013 390891009
66YL.00 Chronic obstructive pulmonary disease follow-up 1488423019 394702007 Y
66YL.11 COPD follow-up 1488423019 394702007 Y
66YM.00 Chronic obstructive pulmonary disease annual review 1488424013 394703002 Y
66YS.00 Chronic obstructive pulmonary disease monitoring by nurse 1780380013 401184000 Y
66YT.00 Chronic obstructive pulmonary disease monitoring by doctor 1780381012 401185004 Y
66Yd.00 Chronic obstructive pulmonary disease accident and emergency attendance since last visit 2533538014 413845009
66Ye.00 Emergency chronic obstructive pulmonary disease admission since last appointment 2533539018 414087000
66Yf.00 Number of chronic obstructive pulmonary disease exacerbations in past year 3335171010 723245007
66Yh.00 Chronic obstructive pulmonary disease does not disturb sleep 299031000000110 198411000000102 Y
66Yi.00 Multiple chronic obstructive pulmonary disease emergency hospital admissions 300201000000114 198901000000105
679V.00 Health education ? chronic obstructive pulmonary disease 3543021016 741056003 Y
6Yg.00 Chronic obstructive pulmonary disease disturbs sleep 299001000000116 198401000000104 Y
8CMW500 Chronic obstructive pulmonary disease care pathway 2199261000000110 848431000000106
8CR1.00 Chronic obstructive pulmonary disease clini management plan 3517019016 736283006 Y
9NgP.00 On chronic obstructive pulmonary disease supportv cre pathway 2149041000000110 826111000000109
9NgP.11 On COPD (chr obstruc pulmonary disease) supportv cre pathway 2155811000000119 826111000000109
9Nk7000 Seen in chronic obstructive pulmonary disease clinic 2219551000000113 857661000000104
9Oi..00 Chronic obstructive pulmonary disease monitoring admin 1564971000000118 713731000000102 Y
9Oi0.00 Chronic obstructive pulmonary disease monitoring 1st letter 1568801000000112 716241000000106 Y
9Oi1.00 Chronic obstructive pulmonary disease monitoring 2nd letter 1569571000000113 717021000000106 Y
9Oi2.00 Chronic obstructive pulmonary disease monitoring 3rd letter 1570061000000113 717521000000104 Y
9Oi3.00 Chronic obstructive pulmonary disease monitoring verb invite 1568831000000118 716281000000103 Y
9Oi4.00 Chronic obstructive pulmonary disease monitor phone invite 1569451000000115 716901000000101 Y
H31..00 Chronic bronchitis 105519017 63480004 Y
H310.00 Simple chronic bronchitis 102938011 61937009 Y
H310000 Chronic catarrhal bronchitis 508562012 89549007 Y
H310z00 Simple chronic bronchitis NOS 102938011 61937009 Y
H311.00 Mucopurulent chronic bronchitis 123588010 74417001 Y
H311000 Purulent chronic bronchitis 506053014 84409004 Y
H311100 Fetid chronic bronchitis 506053014 84409004 Y
H311z00 Mucopurulent chronic bronchitis NOS 123588010 74417001 Y
H312.00 Obstructive chronic bronchitis 285100019 185086009 Y
H312000 Chronic asthmatic bronchitis 301450011 195949008 Y
H312011 Chronic wheezy bronchitis 301451010 195949008
H312100 Emphysematous bronchitis 285100019 185086009 Y Y
H312200 Acute exacerbation of chronic obstructive airways disease 301453013 195951007
H312300 Bronchiolitis obliterans 492443010 40100001 Y
H312z00 Obstructive chronic bronchitis NOS 285100019 185086009 Y Y
H313.00 Mixed simple and mucopurulent chronic bronchitis 301456017 195953005 Y
H31y.00 Other chronic bronchitis 105519017 63480004 Y
H31y100 Chronic tracheobronchitis 87480013 52571006 Y
H31yz00 Other chronic bronchitis NOS 105519017 63480004 Y
H31z.00 Chronic bronchitis NOS 105519017 63480004 Y
H32..00 Emphysema 144964015 8743301 Y Y
H320.00 Chronic bullous emphysema 301460019 195957006 Y Y
H320000 Segmental bullous emphysema 301463017 195958001 Y
H320100 Zonal bullous emphysema 301464011 195959009 Y
H320200 Giant bullous emphysema 27096010 16003001 Y
H320300 Bullous emphysema with collapse 396108018 266355005 Y
H320z00 Chronic bullous emphysema NOS 301460019 195957006 Y Y
H321.00 Panlobular emphysema 9337016 4981000 Y
H322.00 Centrilobular emphysema 113497011 68328006 Y Y
H32y.00 Other emphysema 144964015 87433001 Y
H32y000 Acute vesicular emphysema 301470017 195963002 Y
H32y100 Atrophic (senile) emphysema 396109014 266356006 Y
H32y111 Acute interstitial emphysema 503646013 77690003
H32y200 MacLeod's unilateral emphysema 1230190015 45145000 Y
H32yz00 Other emphysema NOS 144964015 87433001 Y
H32yz11 Sawyer-Jones syndrome 75284014 45145000 Y
H32z.00 Emphysema NOS 144964015 8743301 Y Y
H36..00 Mild chronic obstructive pulmonary disease 457168017 313296004 Y Y
H37..00 Moderate chronic obstructive pulmonary disease 457169013 313297008 Y Y
H38..00 Severe chronic obstructive pulmonary disease 457171013 313299006 Y Y
H39..00 Very severe chronic obstructive pulmonary disease 516801000000112 293991000000106 Y Y
H3?00 Chronic obstructive pulmonary disease 475431013 13645005 Y Y
H3?11 Chronic obstructive airways disease 475423015 13645005 Y Y
H3A..00 End stage chronic obstructive airways disease 216596014 135836000 Y
H3B..00 Asthma-chronic obstructive pulmonary disease overlap syndrome 3046456013 10692761000119107 Y
H3y..00 Other specified chronic obstructive airways disease 475428012 13645005 Y Y
H3y..11 Other specified chronic obstructive pulmonary disease 475431013 13645005 Y
H3y0.00 Chronic obstruct pulmonary dis with acute lower resp infectn 301542016 196001008
H3y1.00 Chron obstruct pulmonary dis wth acute exacerbation, unspec 301453013 195951007
H3z..00 Chronic obstructive airways disease NOS 475428012 13645005 Y Y
H3z..11 Chronic obstructive pulmonary disease NOS 475431013 13645005 Y Y
H464000 Chronic emphysema due to chemical fumes 301572010 196026004 Y
H464100 Obliterative bronchiolitis due to chemical fumes 301573017 196027008 Y
H583200 Eosinophilic bronchitis 2240631000000119 866901000000103 Y
Hyu3000 [X]Other emphysema 144964015 87433001 Y
Hyu3100 [X]Other specified chronic obstructive pulmonary disease 475431013 13645005 Y
Rows: 65
Code Description Validated Read Codes Quint et al. 2014 Description Quality and Outcomes Framework Read Codes 2017/18 Read v2 Code
10692761000119107 Asthma-chronic obstructive pulmonary disease overlap syndrome Y H3B..00
135836000 End stage chronic obstructive airways disease Y H3A..00
13645005 [X]Other specified chronic obstructive pulmonary disease Y Hyu3100
16003001 Giant bullous emphysema Y H320200
170628003 Y Airways obstructn irreversible 663K.00
1823851000006103 Chronic obstructive pulmonary disease confirmed
185086009 Y Emphysematous bronchitis Y H312100
195949008 Chronic asthmatic bronchitis Y H312000
195951007 Acute exacerbation of chronic obstructive airways disease H312200
195953005 Mixed simple and mucopurulent chronic bronchitis Y H313.00
195957006 Y Chronic bullous emphysema Y H320.00
195958001 Segmental bullous emphysema Y H320000
195959009 Zonal bullous emphysema Y H320100
195963002 Acute vesicular emphysema Y H32y000
196001008 Chronic obstruct pulmonary dis with acute lower resp infectn H3y0.00
196026004 Chronic emphysema due to chemical fumes Y H464000
196027008 Obliterative bronchiolitis due to chemical fumes Y H464100
198401000000104 Y Chronic obstructive pulmonary disease disturbs sleep 6Yg.00
198411000000102 Y Chronic obstructive pulmonary disease does not disturb sleep 66Yh.00
198901000000105 Multiple chronic obstructive pulmonary disease emergency hospital admissions 66Yi.00
266355005 Bullous emphysema with collapse Y H320300
266356006 Atrophic (senile) emphysema Y H32y100
270473001 History of chronic obstructive pulmonary disease 14B3.12
293991000000106 Y Very severe chronic obstructive pulmonary disease Y H39..00
313296004 Y Mild chronic obstructive pulmonary disease Y H36..00
313297008 Y Moderate chronic obstructive pulmonary disease Y H37..00
313299006 Y Severe chronic obstructive pulmonary disease Y H38..00
383611000000102 At risk of chronic obstructive pulmonary diseas exacerbation 14OX.00
390891009 Y Chronic obstructive pulmonary disease monitoring 66YB.00
390941006 Y Chronic obstructive pulmonary disease monitoring due 66YD.00
394702007 Y Chronic obstructive pulmonary disease follow-up 66YL.00
394703002 Y Chronic obstructive pulmonary disease annual review 66YM.00
40100001 Bronchiolitis obliterans Y H312300
401184000 Y Chronic obstructive pulmonary disease monitoring by nurse 66YS.00
401185004 Y Chronic obstructive pulmonary disease monitoring by doctor 66YT.00
413845009 Chronic obstructive pulmonary disease accident and emergency attendance since last visit 66Yd.00
414087000 Emergency chronic obstructive pulmonary disease admission since last appointment 66Ye.00
45145000 MacLeod's unilateral emphysema Y H32y200
4981000 Panlobular emphysema Y H321.00
52571006 Chronic tracheobronchitis Y H31y100
61937009 Simple chronic bronchitis Y H310.00
63480004 Chronic bronchitis Y H31..00
68328006 Y Centrilobular emphysema Y H322.00
713731000000102 Y Chronic obstructive pulmonary disease monitoring admin 9Oi..00
716241000000106 Y Chronic obstructive pulmonary disease monitoring 1st letter 9Oi0.00
716281000000103 Y Chronic obstructive pulmonary disease monitoring verb invite 9Oi3.00
716358000 Telehealth chronic obstructive pulmonary disease monitoring 66YB200
716901000000101 Y Chronic obstructive pulmonary disease monitor phone invite 9Oi4.00
717021000000106 Y Chronic obstructive pulmonary disease monitoring 2nd letter 9Oi1.00
717521000000104 Y Chronic obstructive pulmonary disease monitoring 3rd letter 9Oi2.00
723245007 Number of chronic obstructive pulmonary disease exacerbations in past year 66Yf.00
736283006 Y Chronic obstructive pulmonary disease clini management plan 8CR1.00
741056003 Y Health education ? chronic obstructive pulmonary disease 679V.00
74417001 Mucopurulent chronic bronchitis Y H311.00
760601000000107 Chronic obstructive pulmonary disease 3 monthly review 66YB000
760621000000103 Chronic obstructive pulmonary disease 6 monthly review 66YB100
77690003 Acute interstitial emphysema H32y111
826111000000109 On chronic obstructive pulmonary disease supportv cre pathway 9NgP.00
84409004 Fetid chronic bronchitis Y H311100
848431000000106 Chronic obstructive pulmonary disease care pathway 8CMW500
857661000000104 Seen in chronic obstructive pulmonary disease clinic 9Nk7000
866901000000103 Eosinophilic bronchitis Y H583200
87433001 [X]Other emphysema Y Hyu3000
8743301 Y Emphysema Y H32..00
89549007 Chronic catarrhal bronchitis Y H310000
Rows: 3
Code Description Field
1112 Chronic obstructive airways disease/COPD 20002
1113 Emphysema/chronic bronchitis 20002
1472 Emphysema 20002
Rows: 2
Code Description
J43 Emphysema
J44 Other chronic obstructive pulmonary disease
Rows: 2
Code Description
J43 Emphysema
J44 Other chronic obstructive pulmonary disease
Rows: 1
Code Description
CA22 Chronic obstructive pulmonary disease

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH11/version/22/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH11/version/22/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH11', '22', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH11/version/22/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH11/version/22/export/codes/?format=json
CSV site_root/phenotypes/PH11/version/22/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH11', '22', api_client=client)

Version History

Version
ID
Name Owner Publish date
22 COPD ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

Print - Print page.