Drug use

A. John, S. Rees

PH1108 / 3518 Clinical-Coded Phenotype

  1. Overview

    Phenotype Type
    Disease or syndrome
    Sex
    Both
    Valid Event Date Range
    No data
    Coding System
    SNOMED CT codesICD10 codesRead codes v2
    Data Sources
    No data
    Collections
    Adolescent Data Platform (ADP)DATAMINDPhenotype Library
    Tags
    No data
    Ontology
    No data

  2. Definition

    Codes denoting drug use, including findings of drugs in blood, poisoning by drugs, and where drugs have been found to be the cause of other health conditions. The phenotype considers illegal drugs but excludes tobacco, in keeping with the literature. A phenotype for alcohol use is available separately.

    ICD-10 definition

    This definition is based on validated, published and comparable lists (Rees et. al., 2022; DelPozo-Banos et. al., 2018; NHS, 2018; NHS, 2019; Syed et. al., 2018; Walsh et. al., 2018) and reviewed by a clinician in the study team (Prof Ann John).

    Read code definition

    This definition also includes symptoms, observations, medications, behaviours (e.g., “injecting drug user”), referrals and contacts with other services. It contains prescriptions relevant to treatment for drug use disorder (naltrexone, lofexidine and methadone) as almost all recipients were found to have a history of drug use (Rees et. al., 2022); and excludes those used primarily for pain management. For buprenorphine, the list includes only prescriptions where 90% or more recipients had a history of drug use disorder, as assessed during validation (Rees et. al., 2022).

    This definition is based on validated, published and comparable lists (Rees et. al., 2022; DelPozo-Banos et. al., 2018; NHS, 2018; NHS, 2019; Syed et. al., 2018; Walsh et. al., 2018) and reviewed by a clinician in the study team (Prof Ann John).

    SNOMED CT definition

    The SNOMED codes for drug use were developed by mapping the existing ICD-10 and Read code definitions and running complementary SNOMED CT searches. This definition excludes generic terms where the type of the drug cannot be assumed (e.g., ‘Paranoid state caused by drug’). The definition is split in the following concepts:

    • Drug use: Contains all codes that determine the use of illicit drugs at the time of recording.

    • Probable drug use: Contains codes that, while not confirmatory, they are indicative of drug use (e.g., screening for drug use, counselling for drug abuse, etc).

    • History of drug use: Contains codes that indicate a history of drug use prior to the date of recording (e.g., abstinence from drug use).

    Note: The SNOMED CT definition has not undergone validation yet.

    References

    DelPozo-Banos, M., John, A., Petkov, N., Berridge, D. M., Southern, K., LLoyd, K., ... & Travieso, C. M. (2018). Using neural networks with routine health records to identify suicide risk: feasibility study. JMIR mental health, 5(2), e10144.

    NHS National Services Scotland (2018). Alcohol-related hospital statistics Scotland 2017/18.

    NHS National Services Scotland (2019). Drug-related hospital statistics Scotland 2017/18.

    Rees, S., Watkins, A., Keauffling, J., & John, A. (2022). Incidence, Mortality and Survival in Young People with Co-Occurring Mental Disorders and Substance Use: A Retrospective Linked Routine Data Study in Wales. Clinical Epidemiology, 14, 21

    Syed, S., Gilbert, R., & Wolpert, M. (2018). Parental alcohol misuse and the impact on children: a rapid evidence review of service presentations and interventions.

    Walsh E, Jones R, Cox S. (2018). Data mining Wales: the annual profile for substance misuse 2017–18.

  3. Implementation

    Implementation

    No data

  4. Clinical Code List

  5. Publication

    Related publications

    Citation Requirements

    Rees, S., Watkins, A., Keauffling, J., & John, A. (2022). Incidence, mortality and survival in young people with co-occurring mental disorders and substance use: a retrospective linked routine data study in Wales. Clinical Epidemiology, 21-38.

  6. API

    To Export Phenotype Details:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH1108/version/3518/detail/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get details of phenotype

    phenotype_details = client$phenotypes$get_detail(
     'PH1108',
     version_id=3518
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of phenotype

    phenotype_codelist = client.phenotypes.get_detail(
     'PH1108',
     version_id=3518
    )

    To Export Phenotype Code List:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH1108/version/3518/export/codes/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get codelist of phenotype

    phenotype_codelist = client$phenotypes$get_codelist(
     'PH1108',
     version_id=3518
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of phenotype

    phenotype_codelist = client.phenotypes.get_codelist(
     'PH1108',
     version_id=3518
    )

  7. Version History

    Version IDNameOwnerPublish date
    Drug use delpozom2024-07-22 13:41
    2437 Drug use delpozom2023-09-12 11:04