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Vitamin B12 deficiency anaemia

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A

Type
Disease or Syndrome
ID
PH116
Version ID
232
Valid event data range
01/01/1999 - 01/07/2016
Sex
Female, Male
Agreement Date
2019-05-20
Coding system
Read codes v2 ICD10 codes Med codes
Tags /Collections
CALIBER Phenotype Library

Definition

At the specified date, a patient is defined as having had 'Vitamin B12 deficiency anaemia' IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care

  1. 'Vitamin B12 deficiency anaemia' diagnosis or history of diagnosis during a consultation

OR Secondary care (ICD10)

  1. ALL diagnoses of 'Vitamin B12 deficiency anaemia' or history of diagnosis during a hospitalization

Implementation


Publications

  • Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3

Clinical Code List

Rows: 32
Code Description Disease Medcode Category
1452 H/O: Anaemia vit.B12 deficient Vitamin B12 deficiency anaemia 54738 History of Vitamin B12 deficiency anaemia
66E..00 B12 deficiency monitoring Vitamin B12 deficiency anaemia 7403 Vitamin B12 deficiency
66E1.00 B12 defic. initial assessment Vitamin B12 deficiency anaemia 11126 Vitamin B12 deficiency
66E2.00 B12 defic.follow-up assessment Vitamin B12 deficiency anaemia 8013 Vitamin B12 deficiency
66E3.00 B12 injections started Vitamin B12 deficiency anaemia 31126 Vitamin B12 deficiency
66E4.00 B12 injections - at home Vitamin B12 deficiency anaemia 42928 Vitamin B12 deficiency
66E5.00 B12 injections - at surgery Vitamin B12 deficiency anaemia 12329 Vitamin B12 deficiency
66E6.00 Reticulcytosis after B12 Vitamin B12 deficiency anaemia 66935 Diagnosis of Vitamin B12 deficiency anaemia
66E7.00 B12 def.-dubious diag.criteria Vitamin B12 deficiency anaemia 48714 Vitamin B12 deficiency
66E8.00 B12 injections stopped Vitamin B12 deficiency anaemia 58599 Vitamin B12 deficiency
66EZ.00 B12 defic. monitoring NOS Vitamin B12 deficiency anaemia 36840 Vitamin B12 deficiency
C262100 Vitamin B12 deficiency Vitamin B12 deficiency anaemia 2515 Vitamin B12 deficiency
D010.00 Pernicious anaemia Vitamin B12 deficiency anaemia 2464 Diagnosis of Vitamin B12 deficiency anaemia
D010.11 Addison's anaemia Vitamin B12 deficiency anaemia 2813 Diagnosis of Vitamin B12 deficiency anaemia
D010.12 Biermer's congenital pernicious anaemia Vitamin B12 deficiency anaemia 55370 Diagnosis of Vitamin B12 deficiency anaemia
D010.13 Congenital deficiency of intrinsic factor Vitamin B12 deficiency anaemia 46289 Diagnosis of Vitamin B12 deficiency anaemia
D011.00 Other vitamin B12 deficiency anaemias Vitamin B12 deficiency anaemia 29486 Diagnosis of Vitamin B12 deficiency anaemia
D011.11 Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia 5271 Diagnosis of Vitamin B12 deficiency anaemia
D011000 Vitamin B12 deficiency anaemia due to dietary causes Vitamin B12 deficiency anaemia 32953 Diagnosis of Vitamin B12 deficiency anaemia
D011011 Imerslund - Grasbeck syndrome Vitamin B12 deficiency anaemia 72895 Diagnosis of Vitamin B12 deficiency anaemia
D011013 Vegan's anaemia Vitamin B12 deficiency anaemia 69275 Diagnosis of Vitamin B12 deficiency anaemia
D011100 Vit B12 defic anaemia due to malabsorption with proteinuria Vitamin B12 deficiency anaemia 2482 Diagnosis of Vitamin B12 deficiency anaemia
D011200 Transcobalamin II deficiency Vitamin B12 deficiency anaemia 62637 Diagnosis of Vitamin B12 deficiency anaemia
D011X00 Vitamin B12 deficiency anaemia, unspecified Vitamin B12 deficiency anaemia 6028 Diagnosis of Vitamin B12 deficiency anaemia
D011z00 Other vitamin B12 deficiency anaemia NOS Vitamin B12 deficiency anaemia 31270 Diagnosis of Vitamin B12 deficiency anaemia
D013000 Combined B12 and folate deficiency anaemia Vitamin B12 deficiency anaemia 22715 Diagnosis of Vitamin B12 deficiency anaemia
Dyu0100 [X]Other dietary vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia 47952 Diagnosis of Vitamin B12 deficiency anaemia
Dyu0200 [X]Other vitamin B12 deficiency anaemias Vitamin B12 deficiency anaemia 35092 Diagnosis of Vitamin B12 deficiency anaemia
Dyu0600 [X]Vitamin B12 deficiency anaemia, unspecified Vitamin B12 deficiency anaemia 53846 Diagnosis of Vitamin B12 deficiency anaemia
F11x600 Cerebral degeneration due to vitamin B12 deficiency Vitamin B12 deficiency anaemia 24581 Vitamin B12 deficiency
F162.00 Subacute combined degeneration of spinal cord Vitamin B12 deficiency anaemia 7736 Vitamin B12 deficiency
F381500 Myasthenic syndrome due to pernicious anaemia Vitamin B12 deficiency anaemia 56973 Diagnosis of Vitamin B12 deficiency anaemia
Rows: 32
Code Description Disease ReadcodeDescr Readcode
11126 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 defic. initial assessment 66E1.00
12329 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 injections - at surgery 66E5.00
22715 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Combined B12 and folate deficiency anaemia D013000
24581 Vitamin B12 deficiency Vitamin B12 deficiency anaemia Cerebral degeneration due to vitamin B12 deficiency F11x600
2464 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Pernicious anaemia D010.00
2482 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Vit B12 defic anaemia due to malabsorption with proteinuria D011100
2515 Vitamin B12 deficiency Vitamin B12 deficiency anaemia Vitamin B12 deficiency C262100
2813 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Addison's anaemia D010.11
29486 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Other vitamin B12 deficiency anaemias D011.00
31126 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 injections started 66E3.00
31270 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Other vitamin B12 deficiency anaemia NOS D011z00
32953 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia due to dietary causes D011000
35092 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia [X]Other vitamin B12 deficiency anaemias Dyu0200
36840 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 defic. monitoring NOS 66EZ.00
42928 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 injections - at home 66E4.00
46289 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Congenital deficiency of intrinsic factor D010.13
47952 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia [X]Other dietary vitamin B12 deficiency anaemia Dyu0100
48714 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 def.-dubious diag.criteria 66E7.00
5271 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia D011.11
53846 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia [X]Vitamin B12 deficiency anaemia, unspecified Dyu0600
54738 History of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia H/O: Anaemia vit.B12 deficient 1452
55370 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Biermer's congenital pernicious anaemia D010.12
56973 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Myasthenic syndrome due to pernicious anaemia F381500
58599 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 injections stopped 66E8.00
6028 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia, unspecified D011X00
62637 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Transcobalamin II deficiency D011200
66935 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Reticulcytosis after B12 66E6.00
69275 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Vegan's anaemia D011013
72895 Diagnosis of Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Imerslund - Grasbeck syndrome D011011
7403 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 deficiency monitoring 66E..00
7736 Vitamin B12 deficiency Vitamin B12 deficiency anaemia Subacute combined degeneration of spinal cord F162.00
8013 Vitamin B12 deficiency Vitamin B12 deficiency anaemia B12 defic.follow-up assessment 66E2.00
Rows: 1
Code Description Disease Category
D51 Vitamin B12 deficiency anaemia Vitamin B12 deficiency anaemia Diagnosis of Vitamin B12 deficiency anaemia

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH116/version/232/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH116/version/232/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH116', '232', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH116/version/232/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH116/version/232/export/codes/?format=json
CSV site_root/phenotypes/PH116/version/232/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH116', '232', api_client=client)

Version History

Version
ID
Name Owner Publish date
232 Vitamin B12 deficiency anaemia ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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