Severe mental illness (SMI)

Launders N, Richards-Belle A, Hardoon S, Osborn DPJ, Hayes JF

PH1649 / 3407 Clinical-Coded Phenotype

  1. Overview

    Phenotype Type
    Disease or syndrome
    Sex
    Both
    Valid Event Date Range
    No data
    Coding System
    EMIS codesRead codes v2
    Data Sources
    CPRD GOLD
    CPRD Aurum
    Collections
    DATAMIND
    Tags
    No data
    Ontology
    No data

  2. Definition

    The definition of severe mental illness (SMI) is not standardised in the scientific literature. Here we define SMI as presence of schizophrenia, bipolar disorder or other non-organic psychotic illnesses. We include terms included under the Quality and Outcomes Framework (QOF), and some that are not included. We consider historical or resolved codes as indicators of presence of the condition.

  3. Implementation

    Implementation

    Where patients move between specific SMI diagnoses, we have classified them as the most recent diagnosis if considering a specific time point. If considering "ever diagnosed" we have used a hierarchy, taking diagnosis of schizophrenia as the final diagnosis if present, if not bipolar disorder and finally other psychoses. Further information on the implementation of these codes can be found in the DATAMIND SMI and cardiovascular risk factor report: [https://datamind.org.uk/data/harmonised-data/smi-cohorts/]

  4. Clinical Code List

  5. Publication

    Related publications

    • Launders N, Hayes JF, Price G, Marston L, Osborn DPJ. The incidence rate of planned and emergency physical health hospital admissions in people diagnosed with severe mental illness: a cohort study. Psychol Med. 2023

      (DOI: 10.1017/S0033291722002811)

    • Launders N, Kirsh L, Osborn DPJ, Hayes JF. The temporal relationship between severe mental illness diagnosis and chronic physical comorbidity: a UK primary care cohort study of disease burden over 10 years. Lancet Psychiatry. 2022

      (DOI: 10.1016/S2215-0366(22)00225-5)

    • Launders N, Scolamiero L, Osborn DPJ, Hayes JF. Cancer rates and mortality in people with severe mental illness: Further evidence of lack of parity. Schizophr Res. 2022

      (DOI: 10.1016/j.schres.2022.07.008)

    • Launders N, Hayes JF, Price G, Osborn DP. Clustering of physical health multimorbidity in people with severe mental illness: An accumulated prevalence analysis of United Kingdom primary care data. PLoS Med. 2022

      (DOI: 10.1371/journal.pmed.1003976)

    Citation Example

    Launders N, Richards-Belle A, Hardoon S, Osborn DPJ, Hayes JF. PH1649 / 3407 - Severe mental illness (SMI). Phenotype Library [Online]. 11 June 2024. Available from: http://phenotypes.healthdatagateway.org/phenotypes/PH1649/version/3407/detail/. [Accessed 27 January 2025]

  6. API

    To Export Phenotype Details:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH1649/version/3407/detail/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get details of phenotype

    phenotype_details = client$phenotypes$get_detail(
     'PH1649',
     version_id=3407
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of phenotype

    phenotype_codelist = client.phenotypes.get_detail(
     'PH1649',
     version_id=3407
    )

    To Export Phenotype Code List:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH1649/version/3407/export/codes/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get codelist of phenotype

    phenotype_codelist = client$phenotypes$get_codelist(
     'PH1649',
     version_id=3407
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of phenotype

    phenotype_codelist = client.phenotypes.get_codelist(
     'PH1649',
     version_id=3407
    )

  7. Version History

    Version IDNameOwnerPublish date
    Severe mental illness (SMI) nlaunders2024-06-26 10:57