Peripheral arterial disease

PH236 / 472

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A

Oct 6, 2021

Clinical-Coded Phenotype

  1. Overview

    Phenotype Type
    Disease or syndrome
    Sex
    Both
    Valid Event Date Range
    01/01/1999 - 01/07/2016
    Coding System
    ICD10 codesRead codes v2OPCS4 codesMed codes
    Data Sources
    CPRD GOLD
    HES Admitted Patient Care data for CPRD GOLD
    Collections
    CALIBERPhenotype Library
    Tags
    No data
    Ontology
    No data

  2. Definition

    Use MODIFIED CALIBER 'Peripheral arterial disease' (PAD) phenotyping algorithm:

    At the specified date, a patient is considered to have 'Peripheral arterial disease' IF they meet any of the criteria below on or before the specified date.

    The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

    1. Primary care

      1. Peripheral vascular disease diagnosis during a consultation. arterial_gprd: category 7

      2. Record of history of PVD during a consultation. The following Read codes from CPRD:

        1. Read:14F7.00 Medcode: 106762 Descr:H/O: arterial lower limb ulcer

        2. Read:14NB.00 Medcode: 59534 Descr: H/O: Peripheral vascular disease procedure

      3. Leg or aortic embolism or thrombosis diagnosis during a consultation. arterial_gprd: category 8

      4. 'Peripheral arterial disease' procedures, excluding repair of AAA recording during a consultation. pad_opcs_gprd: category 3

      5. Abnormal 'Peripheral arterial disease' (PAD) ultrasound or Doppler study results recorded during a consultation. As per implementation of pad_ud_gprd in CALIBER

      6. Abnormal 'Peripheral arterial disease' angiography results recorded during a consultation. As per implementation of pad_angio_gprd in CALIBER

    2. Secondary care

      1. Primary or secondary diagnosis of Peripheral vascular disease during a hospitalization. arterial_hes: category 7

      2. Primary or secondary diagnosis of leg or aortic embolism or thrombosis during a hospitalization. arterial_hes: category 8

      3. Recording of 'Peripheral arterial disease' procedures, excluding repair of AAA. pad_procs_opcs: category 3

  3. Implementation

    Phenoflow ID

    Please see the PhenoFLOW website here for more information on workflow-based Phenotypes.

    PhenoFLOW Reference: https://kclhi.org/phenoflow/workflows/github.com/phenoflow/Peripheral-arterial-disease---fe2fc8e0-17a2-11ef-9de4-4d4ea830ad16/blob/read-potential-cases-fhir/Peripheral-arterial-disease.cwl

    Implementation

    No data

  4. Clinical Codelist

  5. Publication

    Related publications

    • Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3

      (DOI: 10.1016/S2589-7500(19)30012-3)

    Citation Example

    Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A. PH236 / 472 - Peripheral arterial disease. Phenotype Library [Online]. 06 October 2021. Available from: http://phenotypes.healthdatagateway.org/phenotypes/PH236/version/472/detail/. [Accessed 14 March 2026]

  6. API

    To Export Phenotype Details:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH236/version/472/detail/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get details of Phenotype

    phenotype_details = client$phenotypes$get_detail(
     'PH236',
     version_id=472
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get details of Phenotype

    phenotype_detail = client.phenotypes.get_detail(
     'PH236',
     version_id=472
    )

    To Export Phenotype Code List:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH236/version/472/export/codes/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get codelist of Phenotype

    phenotype_codelist = client$phenotypes$get_codelist(
     'PH236',
     version_id=472
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of Phenotype

    phenotype_codelist = client.phenotypes.get_codelist(
     'PH236',
     version_id=472
    )

  7. Version History

    Version IDNameOwnerPublish date
    Peripheral arterial disease ieuan.scanlon2021-10-06 16:09