Phenotype Library | phenotype: Sickle-cell trait

Sickle-cell trait

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A

PH305

Version ID

610

Type

Disease or Syndrome

Data Sources

CPRD GOLD , HES Admitted Patient Care data for CPRD GOLD

Valid event data range

01/01/1999 - 01/07/2016

Sex

♀ Female ♂ Male

Agreement Date

2019-05-20

Coding system

Read codes v2 ICD10 codes Med codes

Collections

CALIBER Phenotype Library

Definition

At the specified date, a patient is defined as having had Sickle-cell trait IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care

Sickle-cell trait diagnosis or history of diagnosis during a consultation

OR Secondary care (ICD10)

ALL diagnoses of Sickle-cell trait or history of diagnosis during a hospitalization

Implementation

PhenoFlow Implementation:

https://kclhi.org/phenoflow/phenotype/download/890

Publications

Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3

Clinical Code List

CSV

JSON

XML

Expand All / Collapse All

C1559/4257 Sickle-cell trait - Primary care - Read codes v2

Rows: 2

Code	Description	Disease	Medcode	Category
677C600	Sickle cell gene carrier	Sickle-cell trait	106623.0	Diagnosis of Sickle-cell trait
D105.00	Sickle-cell trait	Sickle-cell trait	3616.0	Diagnosis of Sickle-cell trait

C1560/4259 Sickle-cell trait - Primary care - Med codes

Rows: 2

Code	Description	Disease	ReadcodeDescr	Readcode
106623.0	Diagnosis of Sickle-cell trait	Sickle-cell trait	Sickle cell gene carrier	677C600
3616.0	Diagnosis of Sickle-cell trait	Sickle-cell trait	Sickle-cell trait	D105.00

C1561/4261 Sickle-cell trait - Secondary care - Diagnoses - ICD10 codes

Rows: 1

Code	Description	Disease	Category
D57.3	Sickle-cell trait	Sickle-cell trait	Diagnosis of Sickle-cell trait

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH305/version/610/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH305/version/610/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH305', '610', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH305/version/610/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH305/version/610/export/codes/?format=json
CSV	site_root/phenotypes/PH305/version/610/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH305', '610', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
610	Sickle-cell trait	ieuan.scanlon	2021-10-06	currently shown