Antiphospholipid syndrome

PH3280 / 8273

OpenSAFELY

Jan 26, 2026

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OpenCodelists Phenotype

  1. Overview

    Codelist ID
    opensafely/antiphospholipid-syndrome
    Version ID
    3a8c6298
    Coding System
    Read codes v3
    Collections
    OpenCodelistPhenotype Library
    Tags
    No data

  2. Definition

    This codelist was taken from OpenCodelists, created by OpenSAFELY. We recommend viewing this Phenotype on the OpenCodelist website to view the most recent version.

    Codes that indicate incident or history of antiphospholipid syndrome

    © University of Oxford for the Bennett Institute for Applied Data Science 2025. This work may be copied freely for non-commercial research and study.

  3. Methodology

    These codes were mapped first in SNOMED using the opencodelist builder. The search terms used were:

    • antiphospholipid syndrome
    • hughes syndrome
    • lupus

    Though a broad search term, "lupus" was included to capture codes such as Lupus anticoagulant positive". Lupus anticoagulant is synonymous with the detection of antiphospholipid antibodies which is seen in antiphospholipid syndrome. 12 codes were identified in SNOMED.

    The codes were discussed by 2 practicing clinicians and 1 epidemiologist. A summary of the discussion is available on the github issue below.

    These codes were mapped to CTV3 which resulted in 8 codes. One extra TPP CTV3 code was identified from Tree which resulted in 9 codes in total.

  4. References

    Source Reference

    https://www.opencodelists.org/codelist/opensafely/antiphospholipid-syndrome/3a8c6298

    References

  5. Clinical Codelist

  6. API

    To Export Phenotype Details:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH3280/version/8273/detail/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get details of Phenotype

    phenotype_details = client$phenotypes$get_detail(
     'PH3280',
     version_id=8273
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get details of Phenotype

    phenotype_detail = client.phenotypes.get_detail(
     'PH3280',
     version_id=8273
    )

    To Export Phenotype Code List:

    FormatAPI
    JSON site_root/api/v1/phenotypes/PH3280/version/8273/export/codes/?format=json
    R Package

    # Download here

    library(ConceptLibraryClient)


    # Connect to API

    client = ConceptLibraryClient::Connection$new(public=TRUE)


    # Get codelist of Phenotype

    phenotype_codelist = client$phenotypes$get_codelist(
     'PH3280',
     version_id=8273
    )

    Py Package

    # Download here

    from pyconceptlibraryclient import Client


    # Connect to API

    client = Client(public=True)


    # Get codelist of Phenotype

    phenotype_codelist = client.phenotypes.get_codelist(
     'PH3280',
     version_id=8273
    )

  7. Version History

    Version IDNameOwnerPublish date
    Antiphospholipid syndrome ieuan.scanlon2026-01-26 23:09
    8272 Antiphospholipid syndrome ieuan.scanlon2026-01-26 23:09