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Depot APDs

Matthew J Carr, Darren M Ashscroft, Evangelos Kontopantelis, David While, Yvonne Awenant, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb

Type
Drug
ID
PH371
Version ID
742
Data Sources
Valid event data range
01/01/2001 - 31/12/2012
Sex
Female, Male
Agreement Date
2016-03-08
Coding system
Multilex codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Background:

Little is known about the clinical management of patients in primary care following self-harm.

Methods:

A descriptive cohort study using data from 684 UK general practices that contributed to the Clinical Practice Research Datalink (CPRD) during 2001-2013. We identified 49,970 patients with a self-harm episode, 41,500 of whom had one complete year of follow-up.

Results:

Among those with complete follow-up, 26,065 (62.8%, 62.3-63.3) were prescribed psychotropic medication and 6318 (15.2%, 14.9-15.6) were referred to mental health services; 4105 (9.9%, CI 9.6-10.2) were medicated without an antecedent psychiatric diagnosis or referral, and 4,506 (10.9%, CI 10.6-11.2) had a diagnosis but were not subsequently medicated or referred. Patients registered at practices in the most deprived localities were 27.1% (CI 21.5-32.2) less likely to be referred than those in the least deprived. Despite a specifically flagged NICE 'Do not do' recommendation in 2011 against prescribing tricyclic antidepressants following self-harm because of their potentially lethal toxicity in overdose, 8.8% (CI 7.8-9.8) of individuals were issued a prescription in the subsequent year. The percentage prescribed Citalopram, an SSRI antidepressant with higher toxicity in overdose, fell sharply during 2012/2013 in the aftermath of a Medicines and Healthcare products Regulatory Agency (MHRA) safety alert issued in 2011.

Conclusions:

A relatively small percentage of these vulnerable patients are referred to mental health services, and reduced likelihood of referral in more deprived localities reflects a marked health inequality. National clinical guidelines have not yet been effective in reducing rates of tricyclic antidepressant prescribing for this high-risk group.

Publications

  • Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenant, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb, Clinical management following self-harm in a UK-wide primary care cohort. Journal of Affective Disorders, 197(2016) 182-188, 2016.

Clinical Code List

Rows: 56
Code Description Entity type Coding System (Multilex) Category
48900020 Depixol -conc 100mg/ml Injection (Lundbeck Ltd) res36: Depot APDs Multilex drug
50445020 Modecate 25mg/ml Injection (Sanofi-Synthelabo Ltd) res36: Depot APDs Multilex drug
53027020 Clopixol 200mg/ml Oily injection (Lundbeck Ltd) res36: Depot APDs Multilex drug
53030020 Depixol 20mg/ml Injection (Lundbeck Ltd) res36: Depot APDs Multilex drug
53031020 Depixol 40mg/2ml solution for injection ampoules (Lundbeck Ltd) res36: Depot APDs Multilex drug
53053020 Modecate concentrate 100mg/ml Injection (Sanofi-Synthelabo Ltd) res36: Depot APDs Multilex drug
53586020 Piportil 50mg/ml Depot injection (JHC Healthcare Ltd) res36: Depot APDs Multilex drug
57938020 Depixol Low Volume 200mg/1ml solution for injection ampoules (Lundbeck Ltd) res36: Depot APDs Multilex drug
58509020 Haldol decanoate 50mg/1ml solution for injection ampoules (Janssen-Cilag Ltd) res36: Depot APDs Multilex drug
58510020 Haldol decanoate 100mg/1ml solution for injection ampoules (Janssen-Cilag Ltd) res36: Depot APDs Multilex drug
61027020 Fluphenazine decanoate 25mg/1ml solution for injection ampoules (Hospira UK Ltd) res36: Depot APDs Multilex drug
61511020 Zuclopenthixol decanoate 200mg/ml oily injection res36: Depot APDs Multilex drug
61512020 Zuclopenthixol decanoate 500mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
62032020 Flupentixol decanoate 20mg/ml Injection res36: Depot APDs Multilex drug
62033020 Flupentixol decanoate 100mg/ml Injection res36: Depot APDs Multilex drug
62034020 Flupentixol 200mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
62048020 Fluphenazine decanoate 25mg/ml Injection res36: Depot APDs Multilex drug
62049020 Fluphenazine decanoate 100mg/ml Injection res36: Depot APDs Multilex drug
62954020 Fluphenazine decanoate 25mg/ml Injection (Antigen Pharmaceuticals) res36: Depot APDs Multilex drug
63123020 Haloperidol decanoate 50mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
63124020 Haloperidol decanoate 100mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
65842020 Pipotiazine palmitate 50mg/ml depot injection res36: Depot APDs Multilex drug
67405020 Clopixol Conc 500mg/1ml solution for injection ampoules (Lundbeck Ltd) res36: Depot APDs Multilex drug
68096020 Flupentixol 40mg/2ml solution for injection ampoules res36: Depot APDs Multilex drug
89970020 Flupentixol 50mg/0.5ml solution for injection ampoules res36: Depot APDs Multilex drug
89972020 Flupentixol 100mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
89974020 Depixol Conc 50mg/0.5ml solution for injection ampoules (Lundbeck Ltd) res36: Depot APDs Multilex drug
89976020 Depixol Conc 100mg/1ml solution for injection ampoules (Lundbeck Ltd) res36: Depot APDs Multilex drug
91582020 Flupentixol 20mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
91584020 Depixol 20mg/1ml solution for injection ampoules (Lundbeck Ltd) res36: Depot APDs Multilex drug
91592020 Zuclopenthixol decanoate 200mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
91596020 Clopixol 200mg/1ml solution for injection ampoules (Lundbeck Ltd) res36: Depot APDs Multilex drug
91981020 Pipotiazine 50mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
91985020 Pipotiazine 100mg/2ml solution for injection ampoules res36: Depot APDs Multilex drug
91987020 Piportil Depot 50mg/1ml solution for injection ampoules (Sanofi) res36: Depot APDs Multilex drug
91989020 Piportil Depot 100mg/2ml solution for injection ampoules (Sanofi) res36: Depot APDs Multilex drug
92200020 Fluphenazine decanoate 12.5mg/0.5ml solution for injection ampoules res36: Depot APDs Multilex drug
92202020 Fluphenazine decanoate 25mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
92204020 Fluphenazine decanoate 50mg/2ml solution for injection ampoules res36: Depot APDs Multilex drug
92206020 Modecate 12.5mg/0.5ml solution for injection ampoules (Sanofi) res36: Depot APDs Multilex drug
92208020 Modecate 25mg/1ml solution for injection ampoules (Sanofi) res36: Depot APDs Multilex drug
92210020 Modecate 50mg/2ml solution for injection ampoules (Sanofi) res36: Depot APDs Multilex drug
92212020 Fluphenazine decanoate 50mg/0.5ml solution for injection ampoules res36: Depot APDs Multilex drug
92214020 Fluphenazine decanoate 100mg/1ml solution for injection ampoules res36: Depot APDs Multilex drug
92216020 Modecate Concentrate 50mg/0.5ml solution for injection ampoules (Sanofi) res36: Depot APDs Multilex drug
92218020 Modecate Concentrate 100mg/1ml solution for injection ampoules (Sanofi) res36: Depot APDs Multilex drug
98278020 Olanzapine embonate 210mg powder and solvent for suspension for injection vials res36: Depot APDs Multilex drug
98329020 Olanzapine embonate 300mg powder and solvent for suspension for injection vials res36: Depot APDs Multilex drug
99841020 Paliperidone 50mg/0.5ml suspension for injection pre-filled syringes res36: Depot APDs Multilex drug
99843020 Paliperidone 75mg/0.75ml suspension for injection pre-filled syringes res36: Depot APDs Multilex drug
99845020 Paliperidone 100mg/1ml suspension for injection pre-filled syringes res36: Depot APDs Multilex drug
99847020 Paliperidone 150mg/1.5ml suspension for injection pre-filled syringes res36: Depot APDs Multilex drug
99849020 Xeplion 50mg/0.5ml suspension for injection pre-filled syringes (Janssen-Cilag Ltd) res36: Depot APDs Multilex drug
99851020 Xeplion 75mg/0.75ml suspension for injection pre-filled syringes (Janssen-Cilag Ltd) res36: Depot APDs Multilex drug
99853020 Xeplion 100mg/1ml suspension for injection pre-filled syringes (Janssen-Cilag Ltd) res36: Depot APDs Multilex drug
99855020 Xeplion 150mg/1.5ml suspension for injection pre-filled syringes (Janssen-Cilag Ltd) res36: Depot APDs Multilex drug

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH371/version/742/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH371/version/742/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH371', '742', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH371/version/742/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH371/version/742/export/codes/?format=json
CSV site_root/phenotypes/PH371/version/742/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH371', '742', api_client=client)

Version History

Version
ID
Name Owner Publish date
742 Depot APDs ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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