Print

Depression

Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb

Type
Disease or Syndrome
ID
PH373
Version ID
746
Data Sources
Valid event data range
01/01/2001 - 31/12/2013
Sex
Female, Male
Agreement Date
2017-05-01
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

PURPOSE:

Self-harm is a public health problem that requires a better understanding of mortality risk. We undertook a study to examine premature mortality in a nationally representative cohort of primary care patients who had harmed themselves.

METHODS:

During 2001-2013, a total of 385 general practices in England contributed data to the Clinical Practice Research Datalink with linkage to Office for National Statistics mortality records. We identified 30,017 persons aged 15 to 64 years with a recorded episode of self-harm. We estimated the relative risks of all-cause and cause-specific natural and unnatural mortality using a comparison cohort of 600,258 individuals matched on age, sex, and general practice.

RESULTS:

We found an elevated risk of dying prematurely from any cause among the self-harm cohort, especially in the first year of follow-up (adjusted hazard ratio for that year, 3.6; 95% CI, 3.1-4.2). In particular, suicide risk was especially high during the first year (adjusted hazard ratio, 54.4; 95% CI, 34.3-86.3); although it declined sharply, it remained much higher than that in the comparison cohort. Large elevations of risk throughout the follow-up period were also observed for accidental, alcohol-related, and drug poisoning deaths. At 10 years of follow-up, cumulative incidence values were 6.5% (95% CI, 6.0%-7.1%) for allcause mortality and 1.3% (95% CI, 1.2%-1.5%) for suicide.

CONCLUSIONS:

Primary care patients who have harmed themselves are at greatly increased risk of dying prematurely by natural and unnatural causes, and especially within a year of a first episode. These individuals visit clinicians at a relatively high frequency, which presents a clear opportunity for preventive action. Primary care patients with myriad comorbidities, including self-harming behavior, mental disorder, addictions, and physical illnesses, will require concerted, multipronged, multidisciplinary collaborative care approaches.

Publications

  • Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb, Premature Death Among Primary Care Patients With a History of Self-Harm. Annals of Family Medicine, 15(3), 2017.

Clinical Code List

Rows: 105
Code Description Entity type Category Coding System (Read)
1B17.00 Depressed res41: Depression diagnostic Read
2257.00 O/E - depressed res41: Depression diagnostic Read
62T1.00 Puerperal depression res41: Depression diagnostic Read
9kQ..00 On full dose long term treatment depression - enh serv admin res41: Depression diagnostic Read
E001300 Presenile dementia with depression res41: Depression diagnostic Read
E002100 Senile dementia with depression res41: Depression diagnostic Read
E004300 Arteriosclerotic dementia with depression res41: Depression diagnostic Read
E11..12 Depressive psychoses res41: Depression diagnostic Read
E112.00 Single major depressive episode res41: Depression diagnostic Read
E112.11 Agitated depression res41: Depression diagnostic Read
E112.12 Endogenous depression first episode res41: Depression diagnostic Read
E112.13 Endogenous depression first episode res41: Depression diagnostic Read
E112.14 Endogenous depression res41: Depression diagnostic Read
E112000 Single major depressive episode, unspecified res41: Depression diagnostic Read
E112100 Single major depressive episode, mild res41: Depression diagnostic Read
E112200 Single major depressive episode, moderate res41: Depression diagnostic Read
E112300 Single major depressive episode, severe, without psychosis res41: Depression diagnostic Read
E112400 Single major depressive episode, severe, with psychosis res41: Depression diagnostic Read
E112z00 Single major depressive episode NOS res41: Depression diagnostic Read
E113.00 Recurrent major depressive episode res41: Depression diagnostic Read
E113.11 Endogenous depression - recurrent res41: Depression diagnostic Read
E113000 Recurrent major depressive episodes, unspecified res41: Depression diagnostic Read
E113100 Recurrent major depressive episodes, mild res41: Depression diagnostic Read
E113200 Recurrent major depressive episodes, moderate res41: Depression diagnostic Read
E113300 Recurrent major depressive episodes, severe, no psychosis res41: Depression diagnostic Read
E113400 Recurrent major depressive episodes, severe, with psychosis res41: Depression diagnostic Read
E113700 Recurrent depression res41: Depression diagnostic Read
E113z00 Recurrent major depressive episode NOS res41: Depression diagnostic Read
E118.00 Seasonal affective disorder res41: Depression diagnostic Read
E11y200 Atypical depressive disorder res41: Depression diagnostic Read
E11z200 Masked depression res41: Depression diagnostic Read
E135.00 Agitated depression res41: Depression diagnostic Read
E200300 Anxiety with depression res41: Depression diagnostic Read
E204.00 Neurotic depression reactive type res41: Depression diagnostic Read
E204.11 Postnatal depression res41: Depression diagnostic Read
E290.00 Brief depressive reaction res41: Depression diagnostic Read
E290z00 Brief depressive reaction NOS res41: Depression diagnostic Read
E291.00 Prolonged depressive reaction res41: Depression diagnostic Read
E2B..00 Depressive disorder NEC res41: Depression diagnostic Read
E2B0.00 Postviral depression res41: Depression diagnostic Read
E2B1.00 Chronic depression res41: Depression diagnostic Read
Eu20400 [X]Post-schizophrenic depression res41: Depression diagnostic Read
Eu32.00 [X]Depressive episode res41: Depression diagnostic Read
Eu32.11 [X]Single episode of depressive reaction res41: Depression diagnostic Read
Eu32.12 [X]Single episode of psychogenic depression res41: Depression diagnostic Read
Eu32.13 [X]Single episode of reactive depression res41: Depression diagnostic Read
Eu32000 [X]Mild depressive episode res41: Depression diagnostic Read
Eu32100 [X]Moderate depressive episode res41: Depression diagnostic Read
Eu32200 [X]Severe depressive episode without psychotic symptoms res41: Depression diagnostic Read
Eu32211 [X]Single episode agitated depressn w'out psychotic symptoms res41: Depression diagnostic Read
Eu32212 [X]Single episode major depression w'out psychotic symptoms res41: Depression diagnostic Read
Eu32213 [X]Single episode vital depression w'out psychotic symptoms res41: Depression diagnostic Read
Eu32300 [X]Severe depressive episode with psychotic symptoms res41: Depression diagnostic Read
Eu32311 [X]Single episode of major depression and psychotic symptoms res41: Depression diagnostic Read
Eu32312 [X]Single episode of psychogenic depressive psychosis res41: Depression diagnostic Read
Eu32313 [X]Single episode of psychotic depression res41: Depression diagnostic Read
Eu32314 [X]Single episode of reactive depressive psychosis res41: Depression diagnostic Read
Eu32400 [X]Mild depression res41: Depression diagnostic Read
Eu32500 [X]Major depression, mild res41: Depression diagnostic Read
Eu32600 [X]Major depression, moderately severe res41: Depression diagnostic Read
Eu32700 [X]Major depression, severe without psychotic symptoms res41: Depression diagnostic Read
Eu32800 [X]Major depression, severe with psychotic symptoms res41: Depression diagnostic Read
Eu32900 [X]Single major depr ep, severe with psych, psych in remiss res41: Depression diagnostic Read
Eu32A00 [X]Recurr major depr ep, severe with psych, psych in remiss res41: Depression diagnostic Read
Eu32y00 [X]Other depressive episodes res41: Depression diagnostic Read
Eu32y11 [X]Atypical depression res41: Depression diagnostic Read
Eu32y12 [X]Single episode of masked depression NOS res41: Depression diagnostic Read
Eu32z00 [X]Depressive episode, unspecified res41: Depression diagnostic Read
Eu32z11 [X]Depression NOS res41: Depression diagnostic Read
Eu32z12 [X]Depressive disorder NOS res41: Depression diagnostic Read
Eu32z13 [X]Prolonged single episode of reactive depression res41: Depression diagnostic Read
Eu32z14 [X] Reactive depression NOS res41: Depression diagnostic Read
Eu33.00 [X]Recurrent depressive disorder res41: Depression diagnostic Read
Eu33.11 [X]Recurrent episodes of depressive reaction res41: Depression diagnostic Read
Eu33.12 [X]Recurrent episodes of psychogenic depression res41: Depression diagnostic Read
Eu33.13 [X]Recurrent episodes of reactive depression res41: Depression diagnostic Read
Eu33.14 [X]Seasonal depressive disorder res41: Depression diagnostic Read
Eu33.15 [X]SAD - Seasonal affective disorder res41: Depression diagnostic Read
Eu33000 [X]Recurrent depressive disorder, current episode mild res41: Depression diagnostic Read
Eu33100 [X]Recurrent depressive disorder, current episode moderate res41: Depression diagnostic Read
Eu33200 [X]Recurr depress disorder cur epi severe without psyc sympt res41: Depression diagnostic Read
Eu33211 [X]Endogenous depression without psychotic symptoms res41: Depression diagnostic Read
Eu33212 [X]Major depression, recurrent without psychotic symptoms res41: Depression diagnostic Read
Eu33214 [X]Vital depression, recurrent without psychotic symptoms res41: Depression diagnostic Read
Eu33300 [X]Recurrent depress disorder cur epi severe with psyc symp res41: Depression diagnostic Read
Eu33311 [X]Endogenous depression with psychotic symptoms res41: Depression diagnostic Read
Eu33312 [X]Manic-depress psychosis,depressed type+psychotic symptoms res41: Depression diagnostic Read
Eu33313 [X]Recurr severe episodes/major depression+psychotic symptom res41: Depression diagnostic Read
Eu33314 [X]Recurr severe episodes/psychogenic depressive psychosis res41: Depression diagnostic Read
Eu33315 [X]Recurrent severe episodes of psychotic depression res41: Depression diagnostic Read
Eu33316 [X]Recurrent severe episodes/reactive depressive psychosis res41: Depression diagnostic Read
Eu33400 [X]Recurrent depressive disorder, currently in remission res41: Depression diagnostic Read
Eu33y00 [X]Other recurrent depressive disorders res41: Depression diagnostic Read
Eu33z00 [X]Recurrent depressive disorder, unspecified res41: Depression diagnostic Read
Eu33z11 [X]Monopolar depression NOS res41: Depression diagnostic Read
Eu34100 [X]Dysthymia res41: Depression diagnostic Read
Eu34111 [X]Depressive neurosis res41: Depression diagnostic Read
Eu34113 [X]Neurotic depression res41: Depression diagnostic Read
Eu34114 [X]Persistant anxiety depression res41: Depression diagnostic Read
Eu3y111 [X]Recurrent brief depressive episodes res41: Depression diagnostic Read
Eu41200 [X]Mixed anxiety and depressive disorder res41: Depression diagnostic Read
Eu41211 [X]Mild anxiety depression res41: Depression diagnostic Read
Eu53011 [X]Postnatal depression NOS res41: Depression diagnostic Read
Eu53012 [X]Postpartum depression NOS res41: Depression diagnostic Read
Eu92000 [X]Depressive conduct disorder res41: Depression diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH373/version/746/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH373/version/746/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH373', '746', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH373/version/746/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH373/version/746/export/codes/?format=json
CSV site_root/phenotypes/PH373/version/746/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH373', '746', api_client=client)

Version History

Version
ID
Name Owner Publish date
746 Depression ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

Print - Print page.