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Personality Disorder

Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb

Type
Disease or Syndrome
ID
PH385
Version ID
770
Data Sources
Valid event data range
01/01/2001 - 31/12/2013
Sex
Female, Male
Agreement Date
2017-05-01
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

PURPOSE:

Self-harm is a public health problem that requires a better understanding of mortality risk. We undertook a study to examine premature mortality in a nationally representative cohort of primary care patients who had harmed themselves.

METHODS:

During 2001-2013, a total of 385 general practices in England contributed data to the Clinical Practice Research Datalink with linkage to Office for National Statistics mortality records. We identified 30,017 persons aged 15 to 64 years with a recorded episode of self-harm. We estimated the relative risks of all-cause and cause-specific natural and unnatural mortality using a comparison cohort of 600,258 individuals matched on age, sex, and general practice.

RESULTS:

We found an elevated risk of dying prematurely from any cause among the self-harm cohort, especially in the first year of follow-up (adjusted hazard ratio for that year, 3.6; 95% CI, 3.1-4.2). In particular, suicide risk was especially high during the first year (adjusted hazard ratio, 54.4; 95% CI, 34.3-86.3); although it declined sharply, it remained much higher than that in the comparison cohort. Large elevations of risk throughout the follow-up period were also observed for accidental, alcohol-related, and drug poisoning deaths. At 10 years of follow-up, cumulative incidence values were 6.5% (95% CI, 6.0%-7.1%) for allcause mortality and 1.3% (95% CI, 1.2%-1.5%) for suicide.

CONCLUSIONS:

Primary care patients who have harmed themselves are at greatly increased risk of dying prematurely by natural and unnatural causes, and especially within a year of a first episode. These individuals visit clinicians at a relatively high frequency, which presents a clear opportunity for preventive action. Primary care patients with myriad comorbidities, including self-harming behavior, mental disorder, addictions, and physical illnesses, will require concerted, multipronged, multidisciplinary collaborative care approaches.

Publications

  • Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenat, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb, Premature Death Among Primary Care Patients With a History of Self-Harm. Annals of Family Medicine, 15(3), 2017.

Clinical Code List

Rows: 78
Code Description Entity type Category Coding System (Read)
E21..00 Personality disorders res41: Personality disorder diagnostic Read
E21..11 Neurotic personality disorder res41: Personality disorder diagnostic Read
E210.00 Paranoid personality disorder res41: Personality disorder diagnostic Read
E211.00 Affective personality disorder res41: Personality disorder diagnostic Read
E211000 Unspecified affective personality disorder res41: Personality disorder diagnostic Read
E211100 Hypomanic personality disorder res41: Personality disorder diagnostic Read
E211200 Depressive personality disorder res41: Personality disorder diagnostic Read
E211300 Cyclothymic personality disorder res41: Personality disorder diagnostic Read
E211z00 Affective personality disorder NOS res41: Personality disorder diagnostic Read
E212.00 Schizoid personality disorder res41: Personality disorder diagnostic Read
E212000 Unspecified schizoid personality disorder res41: Personality disorder diagnostic Read
E212z00 Schizoid personality disorder NOS res41: Personality disorder diagnostic Read
E213.00 Explosive personality disorder res41: Personality disorder diagnostic Read
E214.00 Compulsive personality disorders res41: Personality disorder diagnostic Read
E214.11 Anancastic personality res41: Personality disorder diagnostic Read
E214000 Anankastic personality res41: Personality disorder diagnostic Read
E214z00 Compulsive personality disorder NOS res41: Personality disorder diagnostic Read
E215.00 Histrionic personality disorders res41: Personality disorder diagnostic Read
E215.11 Hysterical personality disorders res41: Personality disorder diagnostic Read
E215000 Unspecified histrionic personality disorder res41: Personality disorder diagnostic Read
E215z00 Histrionic personality disorder NOS res41: Personality disorder diagnostic Read
E216.00 Inadequate personality disorder res41: Personality disorder diagnostic Read
E217.00 Antisocial or sociopathic personality disorder res41: Personality disorder diagnostic Read
E21y.00 Other personality disorders res41: Personality disorder diagnostic Read
E21y000 Narcissistic personality disorder res41: Personality disorder diagnostic Read
E21y100 Avoidant personality disorder res41: Personality disorder diagnostic Read
E21y200 Borderline personality disorder res41: Personality disorder diagnostic Read
E21y300 Passive-aggressive personality disorder res41: Personality disorder diagnostic Read
E21y400 Eccentric personality disorder res41: Personality disorder diagnostic Read
E21y500 Immature personality disorder res41: Personality disorder diagnostic Read
E21y600 Masochistic personality disorder res41: Personality disorder diagnostic Read
E21y700 Psychoneurotic personality disorder res41: Personality disorder diagnostic Read
E21yz00 Other personality disorder NOS res41: Personality disorder diagnostic Read
E21z.00 Personality disorder NOS res41: Personality disorder diagnostic Read
E21z.11 Psychopathic personality res41: Personality disorder diagnostic Read
Eu06000 [X]Organic personality disorder res41: Personality disorder diagnostic Read
Eu06011 [X]Organic pseudopsychopathic personality res41: Personality disorder diagnostic Read
Eu21.17 [X]Pseudopsychopathic schizophrenia res41: Personality disorder diagnostic Read
Eu21.18 [X]Schizotypal personality disorder res41: Personality disorder diagnostic Read
Eu34011 [X]Affective personality disorder res41: Personality disorder diagnostic Read
Eu34112 [X]Depressive personality disorder res41: Personality disorder diagnostic Read
Eu60.00 [X]Specific personality disorders res41: Personality disorder diagnostic Read
Eu60000 [X]Paranoid personality disorder res41: Personality disorder diagnostic Read
Eu60013 [X]Querulant personality disorder res41: Personality disorder diagnostic Read
Eu60014 [X]Sensitive paranoid personality disorder res41: Personality disorder diagnostic Read
Eu60100 [X]Schizoid personality disorder res41: Personality disorder diagnostic Read
Eu60200 [X]Dissocial personality disorder res41: Personality disorder diagnostic Read
Eu60212 [X]Antisocial personality disorder res41: Personality disorder diagnostic Read
Eu60213 [X]Asocial personality disorder res41: Personality disorder diagnostic Read
Eu60214 [X]Psychopathic personality disorder res41: Personality disorder diagnostic Read
Eu60215 [X]Sociopathic personality disorder res41: Personality disorder diagnostic Read
Eu60300 [X]Emotionally unstable personality disorder res41: Personality disorder diagnostic Read
Eu60311 [X]Aggressive personality disorder res41: Personality disorder diagnostic Read
Eu60312 [X]Borderline personality disorder res41: Personality disorder diagnostic Read
Eu60313 [X]Explosive personality disorder res41: Personality disorder diagnostic Read
Eu60400 [X]Histrionic personality disorder res41: Personality disorder diagnostic Read
Eu60411 [X]Hysterical personality disorder res41: Personality disorder diagnostic Read
Eu60412 [X]Psychoinfantile personality disorder res41: Personality disorder diagnostic Read
Eu60500 [X]Anankastic personality disorder res41: Personality disorder diagnostic Read
Eu60511 [X]Compulsive personality disorder res41: Personality disorder diagnostic Read
Eu60512 [X]Obsessional personality disorder res41: Personality disorder diagnostic Read
Eu60513 [X]Obsessive-compulsive personality disorder res41: Personality disorder diagnostic Read
Eu60600 [X]Anxious [avoidant] personality disorder res41: Personality disorder diagnostic Read
Eu60700 [X]Dependent personality disorder res41: Personality disorder diagnostic Read
Eu60711 [X]Asthenic personality disorder res41: Personality disorder diagnostic Read
Eu60712 [X]Inadequate personality disorder res41: Personality disorder diagnostic Read
Eu60713 [X]Passive personality disorder res41: Personality disorder diagnostic Read
Eu60714 [X]Self defeating personality disorder res41: Personality disorder diagnostic Read
Eu60y00 [X]Other specific personality disorders res41: Personality disorder diagnostic Read
Eu60y11 [X]Eccentric personality disorder res41: Personality disorder diagnostic Read
Eu60y12 [X]Haltlose type personality disorder res41: Personality disorder diagnostic Read
Eu60y13 [X]Immature personality disorder res41: Personality disorder diagnostic Read
Eu60y14 [X]Narcissistic personality disorder res41: Personality disorder diagnostic Read
Eu60y16 [X]Psychoneurotic personality disorder res41: Personality disorder diagnostic Read
Eu60z00 [X]Personality disorder, unspecified res41: Personality disorder diagnostic Read
Eu61.00 [X]Mixed and other personality disorders res41: Personality disorder diagnostic Read
Eu84511 [X]Autistic psychopathy res41: Personality disorder diagnostic Read
Eu94211 [X]Affectionless psychopathy res41: Personality disorder diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH385/version/770/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH385/version/770/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH385', '770', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH385/version/770/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH385/version/770/export/codes/?format=json
CSV site_root/phenotypes/PH385/version/770/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH385', '770', api_client=client)

Version History

Version
ID
Name Owner Publish date
770 Personality Disorder ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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