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Schizophrenia Spectrum

Matthew J Carr, Darren M Ashscroft, Evangelos Kontopantelis, David While, Yvonne Awenant, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb

Type
Disease or Syndrome
ID
PH387
Version ID
774
Data Sources
Valid event data range
01/01/2001 - 31/12/2012
Sex
Female, Male
Agreement Date
2016-03-08
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Background:

Little is known about the clinical management of patients in primary care following self-harm.

Methods:

A descriptive cohort study using data from 684 UK general practices that contributed to the Clinical Practice Research Datalink (CPRD) during 2001-2013. We identified 49,970 patients with a self-harm episode, 41,500 of whom had one complete year of follow-up.

Results:

Among those with complete follow-up, 26,065 (62.8%, 62.3-63.3) were prescribed psychotropic medication and 6318 (15.2%, 14.9-15.6) were referred to mental health services; 4105 (9.9%, CI 9.6-10.2) were medicated without an antecedent psychiatric diagnosis or referral, and 4,506 (10.9%, CI 10.6-11.2) had a diagnosis but were not subsequently medicated or referred. Patients registered at practices in the most deprived localities were 27.1% (CI 21.5-32.2) less likely to be referred than those in the least deprived. Despite a specifically flagged NICE 'Do not do' recommendation in 2011 against prescribing tricyclic antidepressants following self-harm because of their potentially lethal toxicity in overdose, 8.8% (CI 7.8-9.8) of individuals were issued a prescription in the subsequent year. The percentage prescribed Citalopram, an SSRI antidepressant with higher toxicity in overdose, fell sharply during 2012/2013 in the aftermath of a Medicines and Healthcare products Regulatory Agency (MHRA) safety alert issued in 2011.

Conclusions:

A relatively small percentage of these vulnerable patients are referred to mental health services, and reduced likelihood of referral in more deprived localities reflects a marked health inequality. National clinical guidelines have not yet been effective in reducing rates of tricyclic antidepressant prescribing for this high-risk group.

Publications

  • Matthew J Carr, Darren M Ashcroft, Evangelos Kontopantelis, David While, Yvonne Awenant, Jayne Cooper, Carolyn Chew-Graham, Nav Kapur, Roger T Webb, Clinical management following self-harm in a UK-wide primary care cohort. Journal of Affective Disorders, 197(2016) 182-188, 2016.

Clinical Code List

Rows: 194
Code Description Entity type Category Coding System (Read)
1464.00 H/O: schizophrenia res36: Schizophrenia spectrum diagnostic Read
146H.00 H/O: psychosis res36: Schizophrenia spectrum diagnostic Read
1BH..00 Delusions res36: Schizophrenia spectrum diagnostic Read
1BH..11 Delusion res36: Schizophrenia spectrum diagnostic Read
1BH0.00 Delusion of persecution res36: Schizophrenia spectrum diagnostic Read
1BH1.00 Grandiose delusions res36: Schizophrenia spectrum diagnostic Read
1BH2.00 Ideas of reference res36: Schizophrenia spectrum diagnostic Read
1BH3.00 Paranoid ideation res36: Schizophrenia spectrum diagnostic Read
225E.00 O/E - paranoid delusions res36: Schizophrenia spectrum diagnostic Read
225F.00 O/E - delusion of persecution res36: Schizophrenia spectrum diagnostic Read
285..11 Psychotic condition, insight present res36: Schizophrenia spectrum diagnostic Read
286..11 Poor insight into psychotic condition res36: Schizophrenia spectrum diagnostic Read
665E.00 Injectable neuroleptic given res36: Schizophrenia spectrum diagnostic Read
665F.00 On injectable neuroleptic res36: Schizophrenia spectrum diagnostic Read
E1...00 Non-organic psychoses res36: Schizophrenia spectrum diagnostic Read
E10..00 Schizophrenic disorders res36: Schizophrenia spectrum diagnostic Read
E100.00 Simple schizophrenia res36: Schizophrenia spectrum diagnostic Read
E100.11 Schizophrenia simplex res36: Schizophrenia spectrum diagnostic Read
E100000 Unspecified schizophrenia res36: Schizophrenia spectrum diagnostic Read
E100100 Subchronic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E100200 Chronic schizophrenic res36: Schizophrenia spectrum diagnostic Read
E100300 Acute exacerbation of subchronic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E100400 Acute exacerbation of chronic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E100500 Schizophrenia in remission res36: Schizophrenia spectrum diagnostic Read
E100z00 Simple schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E101.00 Hebephrenic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E101000 Unspecified hebephrenic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E101400 Acute exacerbation of chronic hebephrenic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E101500 Hebephrenic schizophrenia in remission res36: Schizophrenia spectrum diagnostic Read
E101z00 Hebephrenic schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E102.00 Catatonic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E102000 Unspecified catatonic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E102100 Subchronic catatonic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E102500 Catatonic schizophrenia in remission res36: Schizophrenia spectrum diagnostic Read
E102z00 Catatonic schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E103.00 Paranoid schizophrenia res36: Schizophrenia spectrum diagnostic Read
E103000 Unspecified paranoid schizophrenia res36: Schizophrenia spectrum diagnostic Read
E103200 Chronic paranoid schizophrenia res36: Schizophrenia spectrum diagnostic Read
E103300 Acute exacerbation of subchronic paranoid schizophrenia res36: Schizophrenia spectrum diagnostic Read
E103400 Acute exacerbation of chronic paranoid schizophrenia res36: Schizophrenia spectrum diagnostic Read
E103500 Paranoid schizophrenia in remission res36: Schizophrenia spectrum diagnostic Read
E103z00 Paranoid schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E104.00 Acute schizophrenic episode res36: Schizophrenia spectrum diagnostic Read
E105.00 Latent schizophrenia res36: Schizophrenia spectrum diagnostic Read
E105000 Unspecified latent schizophrenia res36: Schizophrenia spectrum diagnostic Read
E105200 Chronic latent schizophrenia res36: Schizophrenia spectrum diagnostic Read
E105500 Latent schizophrenia in remission res36: Schizophrenia spectrum diagnostic Read
E105z00 Latent schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E106.00 Residual schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107.00 Schizo-affective schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107.11 Cyclic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107000 Unspecified schizo-affective schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107100 Subchronic schizo-affective schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107200 Chronic schizo-affective schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107300 Acute exacerbation subchronic schizo-affective schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107400 Acute exacerbation of chronic schizo-affective schizophrenia res36: Schizophrenia spectrum diagnostic Read
E107500 Schizo-affective schizophrenia in remission res36: Schizophrenia spectrum diagnostic Read
E107z00 Schizo-affective schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E10y.00 Other schizophrenia res36: Schizophrenia spectrum diagnostic Read
E10y.11 Cenesthopathic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E10y000 Atypical schizophrenia res36: Schizophrenia spectrum diagnostic Read
E10y100 Coenesthopathic schizophrenia res36: Schizophrenia spectrum diagnostic Read
E10yz00 Other schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E10z.00 Schizophrenia NOS res36: Schizophrenia spectrum diagnostic Read
E11z.00 Other and unspecified affective psychoses res36: Schizophrenia spectrum diagnostic Read
E11z000 Unspecified affective psychoses NOS res36: Schizophrenia spectrum diagnostic Read
E11zz00 Other affective psychosis NOS res36: Schizophrenia spectrum diagnostic Read
E12..00 Paranoid states res36: Schizophrenia spectrum diagnostic Read
E120.00 Simple paranoid state res36: Schizophrenia spectrum diagnostic Read
E121.00 Chronic paranoid psychosis res36: Schizophrenia spectrum diagnostic Read
E122.00 Paraphrenia res36: Schizophrenia spectrum diagnostic Read
E123.00 Shared paranoid disorder res36: Schizophrenia spectrum diagnostic Read
E12y.00 Other paranoid states res36: Schizophrenia spectrum diagnostic Read
E12y000 Paranoia querulans res36: Schizophrenia spectrum diagnostic Read
E12yz00 Other paranoid states NOS res36: Schizophrenia spectrum diagnostic Read
E12z.00 Paranoid psychosis NOS res36: Schizophrenia spectrum diagnostic Read
E13..00 Other nonorganic psychoses res36: Schizophrenia spectrum diagnostic Read
E13..11 Reactive psychoses res36: Schizophrenia spectrum diagnostic Read
E130.00 Reactive depressive psychosis res36: Schizophrenia spectrum diagnostic Read
E130.11 Psychotic reactive depression res36: Schizophrenia spectrum diagnostic Read
E131.00 Acute hysterical psychosis res36: Schizophrenia spectrum diagnostic Read
E133.00 Acute paranoid reaction res36: Schizophrenia spectrum diagnostic Read
E134.00 Psychogenic paranoid psychosis res36: Schizophrenia spectrum diagnostic Read
E13y.00 Other reactive psychoses res36: Schizophrenia spectrum diagnostic Read
E13y100 Brief reactive psychosis res36: Schizophrenia spectrum diagnostic Read
E13yz00 Other reactive psychoses NOS res36: Schizophrenia spectrum diagnostic Read
E13z.00 Nonorganic psychosis NOS res36: Schizophrenia spectrum diagnostic Read
E13z.11 Psychotic episode NOS res36: Schizophrenia spectrum diagnostic Read
E14..00 Psychoses with origin in childhood res36: Schizophrenia spectrum diagnostic Read
E141.00 Disintegrative psychosis res36: Schizophrenia spectrum diagnostic Read
E141.11 Heller's syndrome res36: Schizophrenia spectrum diagnostic Read
E141100 Residual disintegrative psychoses res36: Schizophrenia spectrum diagnostic Read
E1y..00 Other specified non-organic psychoses res36: Schizophrenia spectrum diagnostic Read
E1z..00 Non-organic psychosis NOS res36: Schizophrenia spectrum diagnostic Read
Eu02z12 [X] Presenile psychosis NOS res36: Schizophrenia spectrum diagnostic Read
Eu0z.12 [X]Symptomatic psychosis NOS res36: Schizophrenia spectrum diagnostic Read
Eu2..00 [X]Schizophrenia, schizotypal and delusional disorders res36: Schizophrenia spectrum diagnostic Read
Eu20.00 [X]Schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20000 [X]Paranoid schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20011 [X]Paraphrenic schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20100 [X]Hebephrenic schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20111 [X]Disorganised schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20200 [X]Catatonic schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20211 [X]Catatonic stupor res36: Schizophrenia spectrum diagnostic Read
Eu20212 [X]Schizophrenic catalepsy res36: Schizophrenia spectrum diagnostic Read
Eu20213 [X]Schizophrenic catatonia res36: Schizophrenia spectrum diagnostic Read
Eu20214 [X]Schizophrenic flexibilatis cerea res36: Schizophrenia spectrum diagnostic Read
Eu20300 [X]Undifferentiated schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20311 [X]Atypical schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20500 [X]Residual schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20511 [X]Chronic undifferentiated schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20600 [X]Simple schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20y00 [X]Other schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu20y12 [X]Schizophreniform disord NOS res36: Schizophrenia spectrum diagnostic Read
Eu20y13 [X]Schizophrenifrm psychos NOS res36: Schizophrenia spectrum diagnostic Read
Eu20z00 [X]Schizophrenia, unspecified res36: Schizophrenia spectrum diagnostic Read
Eu21.00 [X]Schizotypal disorder res36: Schizophrenia spectrum diagnostic Read
Eu21.11 [X]Latent schizophrenic reaction res36: Schizophrenia spectrum diagnostic Read
Eu21.12 [X]Borderline schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu21.13 [X]Latent schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu21.14 [X]Prepsychotic schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu21.15 [X]Prodromal schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu21.16 [X]Pseudoneurotic schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu22.00 [X]Persistent delusional disorders res36: Schizophrenia spectrum diagnostic Read
Eu22000 [X]Delusional disorder res36: Schizophrenia spectrum diagnostic Read
Eu22011 [X]Paranoid psychosis res36: Schizophrenia spectrum diagnostic Read
Eu22012 [X]Paranoid state res36: Schizophrenia spectrum diagnostic Read
Eu22013 [X]Paraphrenia - late res36: Schizophrenia spectrum diagnostic Read
Eu22014 [X]Sensitiver Beziehungswahn res36: Schizophrenia spectrum diagnostic Read
Eu22015 [X]Paranoia res36: Schizophrenia spectrum diagnostic Read
Eu22100 [X]Delusional misidentification syndrome res36: Schizophrenia spectrum diagnostic Read
Eu22111 [X]Capgras syndrome res36: Schizophrenia spectrum diagnostic Read
Eu22y00 [X]Other persistent delusional disorders res36: Schizophrenia spectrum diagnostic Read
Eu22y11 [X]Delusional dysmorphophobia res36: Schizophrenia spectrum diagnostic Read
Eu22y12 [X]Involutional paranoid state res36: Schizophrenia spectrum diagnostic Read
Eu22y13 [X]Paranoia querulans res36: Schizophrenia spectrum diagnostic Read
Eu22z00 [X]Persistent delusional disorder, unspecified res36: Schizophrenia spectrum diagnostic Read
Eu23.00 [X]Acute and transient psychotic disorders res36: Schizophrenia spectrum diagnostic Read
Eu23000 [X]Acute polymorphic psychot disord without symp of schizoph res36: Schizophrenia spectrum diagnostic Read
Eu23012 [X]Cycloid psychosis res36: Schizophrenia spectrum diagnostic Read
Eu23100 [X]Acute polymorphic psychot disord with symp of schizophren res36: Schizophrenia spectrum diagnostic Read
Eu23112 [X]Cycloid psychosis with symptoms of schizophrenia res36: Schizophrenia spectrum diagnostic Read
Eu23200 [X]Acute schizophrenia-like psychotic disorder res36: Schizophrenia spectrum diagnostic Read
Eu23211 [X]Brief schizophreniform disorder res36: Schizophrenia spectrum diagnostic Read
Eu23212 [X]Brief schizophrenifrm psych res36: Schizophrenia spectrum diagnostic Read
Eu23214 [X]Schizophrenic reaction res36: Schizophrenia spectrum diagnostic Read
Eu23300 [X]Other acute predominantly delusional psychotic disorders res36: Schizophrenia spectrum diagnostic Read
Eu23312 [X]Psychogenic paranoid psychosis res36: Schizophrenia spectrum diagnostic Read
Eu23y00 [X]Other acute and transient psychotic disorders res36: Schizophrenia spectrum diagnostic Read
Eu23z00 [X]Acute and transient psychotic disorder, unspecified res36: Schizophrenia spectrum diagnostic Read
Eu23z11 [X]Brief reactive psychosis NOS res36: Schizophrenia spectrum diagnostic Read
Eu23z12 [X]Reactive psychosis res36: Schizophrenia spectrum diagnostic Read
Eu25.00 [X]Schizoaffective disorders res36: Schizophrenia spectrum diagnostic Read
Eu25000 [X]Schizoaffective disorder, manic type res36: Schizophrenia spectrum diagnostic Read
Eu25011 [X]Schizoaffective psychosis, manic type res36: Schizophrenia spectrum diagnostic Read
Eu25012 [X]Schizophreniform psychosis, manic type res36: Schizophrenia spectrum diagnostic Read
Eu25100 [X]Schizoaffective disorder, depressive type res36: Schizophrenia spectrum diagnostic Read
Eu25111 [X]Schizoaffective psychosis, depressive type res36: Schizophrenia spectrum diagnostic Read
Eu25112 [X]Schizophreniform psychosis, depressive type res36: Schizophrenia spectrum diagnostic Read
Eu25200 [X]Schizoaffective disorder, mixed type res36: Schizophrenia spectrum diagnostic Read
Eu25212 [X]Mixed schizophrenic and affective psychosis res36: Schizophrenia spectrum diagnostic Read
Eu25y00 [X]Other schizoaffective disorders res36: Schizophrenia spectrum diagnostic Read
Eu25z00 [X]Schizoaffective disorder, unspecified res36: Schizophrenia spectrum diagnostic Read
Eu25z11 [X]Schizoaffective psychosis NOS res36: Schizophrenia spectrum diagnostic Read
Eu2y.00 [X]Other nonorganic psychotic disorders res36: Schizophrenia spectrum diagnostic Read
Eu2y.11 [X]Chronic hallucinatory psychosis res36: Schizophrenia spectrum diagnostic Read
Eu2z.00 [X]Unspecified nonorganic psychosis res36: Schizophrenia spectrum diagnostic Read
Eu2z.11 [X]Psychosis NOS res36: Schizophrenia spectrum diagnostic Read
Eu32300 [X]Severe depressive episode with psychotic symptoms res36: Schizophrenia spectrum diagnostic Read
Eu32311 [X]Single episode of major depression and psychotic symptoms res36: Schizophrenia spectrum diagnostic Read
Eu32312 [X]Single episode of psychogenic depressive psychosis res36: Schizophrenia spectrum diagnostic Read
Eu32313 [X]Single episode of psychotic depression res36: Schizophrenia spectrum diagnostic Read
Eu32314 [X]Single episode of reactive depressive psychosis res36: Schizophrenia spectrum diagnostic Read
Eu32900 [X]Single major depr ep, severe with psych, psych in remiss res36: Schizophrenia spectrum diagnostic Read
Eu32A00 [X]Recurr major depr ep, severe with psych, psych in remiss res36: Schizophrenia spectrum diagnostic Read
Eu33300 [X]Recurrent depress disorder cur epi severe with psyc symp res36: Schizophrenia spectrum diagnostic Read
Eu33311 [X]Endogenous depression with psychotic symptoms res36: Schizophrenia spectrum diagnostic Read
Eu33313 [X]Recurr severe episodes/major depression+psychotic symptom res36: Schizophrenia spectrum diagnostic Read
Eu33314 [X]Recurr severe episodes/psychogenic depressive psychosis res36: Schizophrenia spectrum diagnostic Read
Eu33315 [X]Recurrent severe episodes of psychotic depression res36: Schizophrenia spectrum diagnostic Read
Eu33316 [X]Recurrent severe episodes/reactive depressive psychosis res36: Schizophrenia spectrum diagnostic Read
Eu44.14 [X]Hysterical psychosis res36: Schizophrenia spectrum diagnostic Read
Eu84312 [X]Disintegrative psychosis res36: Schizophrenia spectrum diagnostic Read
Eu84314 [X]Symbiotic psychosis res36: Schizophrenia spectrum diagnostic Read
R001.00 [D]Hallucinations res36: Schizophrenia spectrum diagnostic Read
R001000 [D]Hallucinations, auditory res36: Schizophrenia spectrum diagnostic Read
R001100 [D]Hallucinations, gustatory res36: Schizophrenia spectrum diagnostic Read
R001200 [D]Hallucinations, olfactory res36: Schizophrenia spectrum diagnostic Read
R001300 [D]Hallucinations, tactile res36: Schizophrenia spectrum diagnostic Read
R001400 [D]Visual hallucinations res36: Schizophrenia spectrum diagnostic Read
R001z00 [D]Hallucinations NOS res36: Schizophrenia spectrum diagnostic Read
Ryu5300 [X]Other hallucinations res36: Schizophrenia spectrum diagnostic Read
ZS7C611 Schizophrenic language res36: Schizophrenia spectrum diagnostic Read
ZV11000 [V]Personal history of schizophrenia res36: Schizophrenia spectrum diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH387/version/774/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH387/version/774/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH387', '774', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH387/version/774/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH387/version/774/export/codes/?format=json
CSV site_root/phenotypes/PH387/version/774/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH387', '774', api_client=client)

Version History

Version
ID
Name Owner Publish date
774 Schizophrenia Spectrum ieuan.scanlon 2021-10-06 currently shown

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