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Screen Breast

Matthew Carr, Evan Kontopantelis, Tim Doran, Christine Campbell, Lorraine Lipscombe, Emma Crosbie, Anothony Howell, Iain E Buchan, Andrew G Renehan

Type
Biomarker
ID
PH388
Version ID
776
Data Sources
Valid event data range
1999 - 2011
Sex
Female
Agreement Date
2015-01-01
Coding system
Read codes v2 OXMIS codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Aims/hypothesis:

Studies from healthcare databases suggest that patients with type 2 diabetes (T2D) under-utilize cancer screening opportunities, but recording bias may be a problem. We evaluated the relative effect of T2D on screening utilization trends among long-established UK national programmes in breast and cervical cancers; and tested the impact of introducing a primary care financial incentive scheme (QOF) in 2004, known to improve data recording for diabetes-related care.

Materials and methods:

Using the Clinical Practice Research Datalink, we identified women with prevalent T2DM (N = 174,256), separately by year for 1999 to 2011, and eligible for screening events for breast (aged 50-70 years) and cervical (aged 35-49 and 50-64 years) cancers. We described secular trends and compared these with the non-diabetes population, and accounted for co-morbidities using matched conditional logistic regression models. We performed interrupted time-series (ITS) analyses to assess the impact of the QOF introduction.

Results:

Compared with the non-diabetes population, relative uptake rates for breast and cervical screening were generally similar in patients with T2D pre-2004, becoming greater for years post-2004. These patterns were unaffected by adjustment for GP practice, and were not accounted for by T2D associated co-morbidities. ITS analysis showed increased activities in all three screening groups for 2007, but these broadly returned to pre-2004 trends by 2011, paralleling similar patterns in recording for other care provision indicators.

Conclusions/interpretation:

In this population, we found no evidence that women with T2D under-utilize breast and cervical cancer screening opportunities. A financial incentive scheme was associated with intermediate-term improvements in screening utilization, but this is likely to reflect improved recording of care events.

Publications

  • Magthew Carr, Even Kontopantelis, Tim Doran, Christian Campbell, Lorraine Lipscombe, Emma Crosbie, Anthony Howell, Iain E Buchan, Andrew G Renehan, Breast and Cervical Cancer Screening Utilization, and recording bias, in women with type 2 diabetes (UK). 2015.

Clinical Code List

Rows: 42
Code Description Entity type Coding System (OXMIS Read) Category
1A81.00 No breast lump res22: screen_breast Read test
1A82.00 Breast lump present res22: screen_breast Read test
1A84.00 Breast lump detected by mammogram res22: screen_breast Read test
537..00 Soft tissue X-ray breast res22: screen_breast Read test
537..11 Mammography - X-ray res22: screen_breast Read test
5371.00 Mammography requested res22: screen_breast Read test
5372.00 Mammography normal res22: screen_breast Read test
5373.00 Mammography abnormal res22: screen_breast Read test
5374.00 Mammography offered res22: screen_breast Read test
5376.00 Mammography attended res22: screen_breast Read test
537Z.00 Soft tissue X-ray breast NOS res22: screen_breast Read test
54L3.00 Mammary gland contrast radiog. res22: screen_breast Read test
54L3.11 Breast contrast radiog res22: screen_breast Read test
54L3.12 Mammary contrast radiog res22: screen_breast Read test
56B1.00 Specific mammary gland imaging res22: screen_breast Read test
585C.00 US scan of breast res22: screen_breast Read test
5861.00 Thermography - breast res22: screen_breast Read test
5861.11 Mammogram-thermographic res22: screen_breast Read test
6862.00 Breast neoplasm screen res22: screen_breast Read test
6862.11 Mammography - screening res22: screen_breast Read test
6862000 Breast neoplasm screen normal res22: screen_breast Read test
6862100 Breast neoplasm screen abnorm res22: screen_breast Read test
6862Z00 Breast neoplasm screen NOS res22: screen_breast Read test
6865.00 Breast neoplasm screen normal res22: screen_breast Read test
7P0F.00 Diagnostic imaging of breast res22: screen_breast Read test
7P0F000 Scintimammography res22: screen_breast Read test
7P0F100 Thermography of breast res22: screen_breast Read test
7P0F200 Mammography res22: screen_breast Read test
7P0Fy00 Other specified diagnostic imaging of breast res22: screen_breast Read test
7P0Fz00 Diagnostic imaging of breast NOS res22: screen_breast Read test
8HT8.00 Referral to mammography clinic res22: screen_breast Read test
8HTI.00 Referral to breast clinic res22: screen_breast Read test
9N0A.00 Seen in breast clinic res22: screen_breast Read test
9N1y900 Seen in breast clinic res22: screen_breast Read test
9Np2.00 Seen in fast track suspected breast cancer clinic res22: screen_breast Read test
9OH9.00 Breast screen abnorm.-told pat res22: screen_breast Read test
9OHZ.00 Breast screening administr.NOS res22: screen_breast Read test
9Oq8.00 Attended breast screening clinic res22: screen_breast Read test
R138.00 [D]Breast imaging abnormal res22: screen_breast Read test
R138000 [D]Mammogram abnormal res22: screen_breast Read test
R138z00 [D]Breast imaging abnormal NOS res22: screen_breast Read test
ZV76100 [V]Screening for malignant neoplasm of breast res22: screen_breast Read test
Rows: 8
Code Description Entity type Coding System (OXMIS Read) Category
L0010CB SEEN IN MAMMOGRAPHY CLINIC res22: screen_breast OXMIS test
L0010GB REFERRED TO MAMMOGRAPHY CLINIC res22: screen_breast OXMIS test
X9110 MAMMOGRAM res22: screen_breast OXMIS test
X9111 MAMMOGRAM NORMAL res22: screen_breast OXMIS test
X9111AB MAMMOGRAM ABNORMAL res22: screen_breast OXMIS test
Y060 E BREAST SCREENING EXAMINATION res22: screen_breast OXMIS test
Y1000HB BREAST SCREENING res22: screen_breast OXMIS test
Y600 EN BREAST SCREENING EXAMINATION NORMAL res22: screen_breast OXMIS test

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH388/version/776/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH388/version/776/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH388', '776', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH388/version/776/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH388/version/776/export/codes/?format=json
CSV site_root/phenotypes/PH388/version/776/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH388', '776', api_client=client)

Version History

Version
ID
Name Owner Publish date
776 Screen Breast ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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