Phenotype Library | phenotype: Screen Cervical

Screen Cervical

Matthew Carr, Evan Kontopantelis, Tim Doran, Christine Campbell, Lorraine Lipscombe, Emma Crosbie, Anothony Howell, Iain E Buchan, Andrew G Renehan

PH389

Version ID

778

Type

Biomarker

Data Sources

CPRD GOLD

Valid event data range

1999 - 2011

Sex

♀ Female

Agreement Date

2015-01-01

Coding system

Read codes v2 OXMIS codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

Aims/hypothesis:

Studies from healthcare databases suggest that patients with type 2 diabetes (T2D) under-utilize cancer screening opportunities, but recording bias may be a problem. We evaluated the relative effect of T2D on screening utilization trends among long-established UK national programmes in breast and cervical cancers; and tested the impact of introducing a primary care financial incentive scheme (QOF) in 2004, known to improve data recording for diabetes-related care.

Materials and methods:

Using the Clinical Practice Research Datalink, we identified women with prevalent T2DM (N = 174,256), separately by year for 1999 to 2011, and eligible for screening events for breast (aged 50-70 years) and cervical (aged 35-49 and 50-64 years) cancers. We described secular trends and compared these with the non-diabetes population, and accounted for co-morbidities using matched conditional logistic regression models. We performed interrupted time-series (ITS) analyses to assess the impact of the QOF introduction.

Results:

Compared with the non-diabetes population, relative uptake rates for breast and cervical screening were generally similar in patients with T2D pre-2004, becoming greater for years post-2004. These patterns were unaffected by adjustment for GP practice, and were not accounted for by T2D associated co-morbidities. ITS analysis showed increased activities in all three screening groups for 2007, but these broadly returned to pre-2004 trends by 2011, paralleling similar patterns in recording for other care provision indicators.

Conclusions/interpretation:

In this population, we found no evidence that women with T2D under-utilize breast and cervical cancer screening opportunities. A financial incentive scheme was associated with intermediate-term improvements in screening utilization, but this is likely to reflect improved recording of care events.

Publications

Magthew Carr, Even Kontopantelis, Tim Doran, Christian Campbell, Lorraine Lipscombe, Emma Crosbie, Anthony Howell, Iain E Buchan, Andrew G Renehan, Breast and Cervical Cancer Screening Utilization, and recording bias, in women with type 2 diabetes (UK). 2015.

Clinical Code List

CSV

JSON

XML

Expand All / Collapse All

C1720/4578 Screen Cervical - Primary Care - Read codes v2

Rows: 79

Code	Description	Entity type	Coding System (OXMIS Read)	Category
4149.00	Cervical cytology sample sent to laboratory	res22: screen_cervical	Read	test
4JRL.00	Cervical cytology screening test	res22: screen_cervical	Read	test
4K2..00	Cervical smear result	res22: screen_cervical	Read	test
4K2..11	Dyskaryosis on cervical smear	res22: screen_cervical	Read	test
4K2..12	Dysplasia (dysk.)on cerv.smear	res22: screen_cervical	Read	test
4K21.00	Cervical smear:inadequate spec	res22: screen_cervical	Read	test
4K22.00	Cervical smear: negative	res22: screen_cervical	Read	test
4K22.11	Smear NAD: no endocervic cells	res22: screen_cervical	Read	test
4K23.00	Cerv.smear: mild dyskaryosis	res22: screen_cervical	Read	test
4K24.00	Cerv.smear: severe dyskaryosis	res22: screen_cervical	Read	test
4K25.00	Cerv.smear:severe dysk.?inv.ca	res22: screen_cervical	Read	test
4K26.00	Cervical smear: ? gland neopl.	res22: screen_cervical	Read	test
4K27.00	Cervical smear:atrophic change	res22: screen_cervical	Read	test
4K27.11	Atrophic change on cerv.smear	res22: screen_cervical	Read	test
4K28.00	Cerv.smear: mod.dyskaryosis	res22: screen_cervical	Read	test
4K29.00	Cerv.smear: borderline changes	res22: screen_cervical	Read	test
4K2A.00	Cervical smear endocervical cells present	res22: screen_cervical	Read	test
4K2B.00	Cervical smear endocervical cells absent	res22: screen_cervical	Read	test
4K2C.00	Smear NAD - no endocervical cells	res22: screen_cervical	Read	test
4K2D.00	Cervical smear transformation zone cells present	res22: screen_cervical	Read	test
4K2E.00	Cervical smear transformation zone cells absent	res22: screen_cervical	Read	test
4K2F.00		res22: screen_cervical	Read	test
4K2Z.00	Cervical smear result NOS	res22: screen_cervical	Read	test
4K2Z.11	Nuclear abnormality on smear	res22: screen_cervical	Read	test
4K3..00	Cervical smear - inflam.change	res22: screen_cervical	Read	test
4K31.00	Cervical smear-no inflammation	res22: screen_cervical	Read	test
4K32.00	Cervical smear-severe inflamm.	res22: screen_cervical	Read	test
4K33.00	Cervical smear - trichomonas	res22: screen_cervical	Read	test
4K34.00	Cervical smear - candida	res22: screen_cervical	Read	test
4K35.00	Cerv.smear - viral infl.unsp.	res22: screen_cervical	Read	test
4K35.11	Viral changes on cerv. smear	res22: screen_cervical	Read	test
4K36.00	Cervical smear - wart virus	res22: screen_cervical	Read	test
4K36.12	HPV changes: cervical smear	res22: screen_cervical	Read	test
4K3A.00	Cervical smear: koilocytosis	res22: screen_cervical	Read	test
4K3B.00	Cervical smear - mild inflammation	res22: screen_cervical	Read	test
4K3C.00	Cervical smear - moderate inflammation	res22: screen_cervical	Read	test
4K3Z.00	Cervical smear - inflam. NOS	res22: screen_cervical	Read	test
4K4..00	Cervical smear - action needed	res22: screen_cervical	Read	test
4K48.00	Cx. smear: colposcopy needed	res22: screen_cervical	Read	test
4K49.00	Cx. smear:cervical biopsy need	res22: screen_cervical	Read	test
4K4Z.00	Cervical smear action NOS	res22: screen_cervical	Read	test
4K55.00	Cervical cytology test	res22: screen_cervical	Read	test
4KA..00	Vaginal vault smear result	res22: screen_cervical	Read	test
4KA1.00	Vaginal vault smear negative	res22: screen_cervical	Read	test
4KA4.00	Vaginal vault smear abnormal	res22: screen_cervical	Read	test
685..00	Cervical neoplasia screening	res22: screen_cervical	Read	test
685..11	Cervical cytology screen	res22: screen_cervical	Read	test
685..12	Cervical smear screen	res22: screen_cervical	Read	test
6859.00	Ca cervix - screen done	res22: screen_cervical	Read	test
6859.11	Cervical cytology examination	res22: screen_cervical	Read	test
685A.00	Ca cervix screen-no result yet	res22: screen_cervical	Read	test
685B.00	Ca cervix screen normal	res22: screen_cervical	Read	test
685C.00	Ca cervix screen abnormal	res22: screen_cervical	Read	test
685D.00	Ca cervix screen + fee claim	res22: screen_cervical	Read	test
685E.00	Cervical smear status unknown	res22: screen_cervical	Read	test
685R.00	Liquid based cervical cytology screening	res22: screen_cervical	Read	test
685Z.00	Ca cervix screen NOS	res22: screen_cervical	Read	test
7E2A000	Exam female genital tract under anaesth & Papanicolau smear	res22: screen_cervical	Read	test
7E2A200	Papanicolau smear NEC	res22: screen_cervical	Read	test
7E2A211	Cervical smear NEC	res22: screen_cervical	Read	test
7E2A300	Vaginal vault smear	res22: screen_cervical	Read	test
981..00	FP74 - cervical cytology claim	res22: screen_cervical	Read	test
981..11	Cervical smear - fee claim	res22: screen_cervical	Read	test
9O81.00	Cervical smear - 1st call	res22: screen_cervical	Read	test
9O8A.00	Abnormal smear - 1st recall	res22: screen_cervical	Read	test
9O8R.00	Smear normal - pt. notified	res22: screen_cervical	Read	test
9O8T.00	Cervical smear slide lost in transit	res22: screen_cervical	Read	test
9O8U.00	Cervical smear slide broken in transit	res22: screen_cervical	Read	test
9O8V.00	Place cervical smear taken	res22: screen_cervical	Read	test
R150.00	[D]Nonspecific abnormal Papanicolaou cervical smear	res22: screen_cervical	Read	test
R150.11	[D]Cervical smear - nonspecific abnormality	res22: screen_cervical	Read	test
R150.12	[D]Papanicolaou smear - nonspecific abnormality	res22: screen_cervical	Read	test
R150000	[D]Dyskaryotic cervical smear	res22: screen_cervical	Read	test
R150100	[D] Koilocytosis - cervical smear	res22: screen_cervical	Read	test
R150z00	[D]Nonspecific abnormal Papanicolaou cervical smear NOS	res22: screen_cervical	Read	test
R151.00	[D]Nonspecific abnormal Papanicolaou smear of other origin	res22: screen_cervical	Read	test
ZV76200	[V]Screening for malignant neoplasm of cervix	res22: screen_cervical	Read	test
ZV76211	[V]Routine Papanicolaou smear	res22: screen_cervical	Read	test
ZV76212	[V]Routine cervical smear	res22: screen_cervical	Read	test

C1721/4580 Screen Cervical - Primary Care - OXMIS codes

Rows: 12

Code	Description	Entity type	Coding System (OXMIS Read)	Category
9O89.00	SMEAR ABNORMAL - PATIENT TOLD	res22: screen_cervical	OXMIS	test
9O89.11	SMEAR ABNORMAL - PT. NOTIFIED	res22: screen_cervical	OXMIS	test
L3230T	CERVICAL SMEAR TAKEN	res22: screen_cervical	OXMIS	test
L9160	PAP SMEAR EXAMINATION	res22: screen_cervical	OXMIS	test
L9160NG	PAP SMEAR NEGATIVE	res22: screen_cervical	OXMIS	test
L9161AC	CERVICAL SMEAR ABNORMAL	res22: screen_cervical	OXMIS	test
L9162	CERVICAL SMEAR	res22: screen_cervical	OXMIS	test
L9162BA	SMEAR INFLAMED	res22: screen_cervical	OXMIS	test
L9162N	NEGATIVE - CERVICAL SMEAR	res22: screen_cervical	OXMIS	test
L9162PJ	CARCINOMA IN SITU - CERVICAL SMEAR	res22: screen_cervical	OXMIS	test
L9162PP	CERVICAL SMEAR CIN I	res22: screen_cervical	OXMIS	test
L9162PQ	CERVICAL SMEAR CIN II	res22: screen_cervical	OXMIS	test

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH389/version/778/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH389/version/778/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH389', '778', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH389/version/778/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH389/version/778/export/codes/?format=json
CSV	site_root/phenotypes/PH389/version/778/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH389', '778', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
778	Screen Cervical	ieuan.scanlon	2021-10-06	currently shown