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Angiotensin-Iireceptorantagonists

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves

Type
Drug
ID
PH403
Version ID
806
Data Sources
Valid event data range
01/01/2000 - 31/12/2007
Sex
Female, Male
Agreement Date
2011-06-28
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.

Publications

  • Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011.

Clinical Code List

Rows: 81
Code Description Entity type Category Coding System (GPRD_product_code)
10485001 VALSARTAN caps 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
10485002 VALSARTAN caps 80mg Angiotensin-II receptor antagonists drug GPRD_product_code
10485003 VALSARTAN caps 160mg Angiotensin-II receptor antagonists drug GPRD_product_code
10486001 DIOVAN caps 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
10486002 DIOVAN caps 80mg Angiotensin-II receptor antagonists drug GPRD_product_code
10486003 DIOVAN caps 160mg Angiotensin-II receptor antagonists drug GPRD_product_code
10707001 COAPROVEL tabs 150mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
10707002 COAPROVEL tabs 300mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
10716001 EPROSARTAN tabs 300mg Angiotensin-II receptor antagonists drug GPRD_product_code
10716002 EPROSARTAN tabs 400mg Angiotensin-II receptor antagonists drug GPRD_product_code
10716003 EPROSARTAN tabs 600mg Angiotensin-II receptor antagonists drug GPRD_product_code
10717001 TEVETEN tabs 300mg Angiotensin-II receptor antagonists drug GPRD_product_code
10717002 TEVETEN tabs 400mg Angiotensin-II receptor antagonists drug GPRD_product_code
10717003 TEVETEN tabs 600mg Angiotensin-II receptor antagonists drug GPRD_product_code
11492001 IRBESARTAN tabs 75mg Angiotensin-II receptor antagonists drug GPRD_product_code
11492002 IRBESARTAN tabs 150mg Angiotensin-II receptor antagonists drug GPRD_product_code
11492003 IRBESARTAN tabs 300mg Angiotensin-II receptor antagonists drug GPRD_product_code
11493001 APROVEL tabs 75mg Angiotensin-II receptor antagonists drug GPRD_product_code
11493002 APROVEL tabs 150mg Angiotensin-II receptor antagonists drug GPRD_product_code
11493003 APROVEL tabs 300mg Angiotensin-II receptor antagonists drug GPRD_product_code
11664001 AMIAS tabs 16mg Angiotensin-II receptor antagonists drug GPRD_product_code
12571001 VALSARTAN + HYDROCHLOROTHIAZIDE tabs 160mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
12572001 HYDROCHLOROTHIAZIDE + VALSARTAN tabs 12.5mg + 160mg Angiotensin-II receptor antagonists drug GPRD_product_code
12573001 CO-DIOVAN tabs 160mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
12575001 VALSARTAN + HYDROCHLOROTHIAZIDE tabs 160mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
12577001 HYDROCHLOROTHIAZIDE + VALSARTAN tabs 25mg + 160mg Angiotensin-II receptor antagonists drug GPRD_product_code
12578001 CO-DIOVAN tabs 160mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
12785001 VALSARTAN + HYDROCHLOROTHIAZIDE tabs 80mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
12786001 HYDROCHLOROTHIAZIDE + VALSARTAN tabs 12.5mg + 80mg Angiotensin-II receptor antagonists drug GPRD_product_code
12787001 CO-DIOVAN tabs 80mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
12846001 VALSARTAN tabs 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
12847001 DIOVAN tabs 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
12971001 CANDESARTAN tabs 32mg Angiotensin-II receptor antagonists drug GPRD_product_code
12972001 AMIAS tabs 32mg Angiotensin-II receptor antagonists drug GPRD_product_code
13477001 LOSARTAN + HYDROCHLOROTHIAZIDE tabs 100mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
13478001 HYDROCHLOROTHIAZIDE + LOSARTAN tabs 25mg + 100mg Angiotensin-II receptor antagonists drug GPRD_product_code
13479001 COZAAR-COMP tabs 100mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
13906001 OLMESARTAN MEDOXOMIL + HYDROCHLOROTHIAZIDE tabs 20mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
13907001 OLMESARTAN MEDOXOMIL + HYDROCHLOROTHIAZIDE tabs 20mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
13909001 OLMETEC PLUS tabs 20mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
13910001 OLMETEC PLUS tabs 20mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
13959001 HYDROCHLOROTHIAZIDE + OLMESARTAN MEDOXOMIL tabs 25mg + 20mg Angiotensin-II receptor antagonists drug GPRD_product_code
13960001 HYDROCHLOROTHIAZIDE + OLMESARTAN MEDOXOMIL tabs 12.5mg + 20mg Angiotensin-II receptor antagonists drug GPRD_product_code
14583001 VALSARTAN (IPU) tabs 80mg Angiotensin-II receptor antagonists drug GPRD_product_code
14585001 VALSARTAN (IPU) tabs 160mg Angiotensin-II receptor antagonists drug GPRD_product_code
14780001 IRBESARTAN + HYDROCHLOROTHIAZIDE tabs 300mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
14781001 COAPROVEL tabs 300mg + 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
2350001 OLMETEC tabs 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
2748001 TELMISARTAN + HYDROCHLOROTHIAZIDE tabs 80mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
313001 MICARDIS PLUS tabs 80mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
7009001 TELMISARTAN tabs 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
7009002 TELMISARTAN tabs 80mg Angiotensin-II receptor antagonists drug GPRD_product_code
7009003 TELMISARTAN tabs 20mg Angiotensin-II receptor antagonists drug GPRD_product_code
7482001 COZAAR tabs 50mg Angiotensin-II receptor antagonists drug GPRD_product_code
7482002 COZAAR tabs 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
7483001 LOSARTAN tabs 50mg Angiotensin-II receptor antagonists drug GPRD_product_code
7483002 LOSARTAN tabs 25mg Angiotensin-II receptor antagonists drug GPRD_product_code
8126001 OLMESARTAN MEDOXOMIL tabs 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
8127001 OLMESARTAN MEDOXOMIL tabs 10mg Angiotensin-II receptor antagonists drug GPRD_product_code
8131001 OLMETEC tabs 20mg Angiotensin-II receptor antagonists drug GPRD_product_code
8132001 OLMETEC tabs 10mg Angiotensin-II receptor antagonists drug GPRD_product_code
8138001 OLMESARTAN MEDOXOMIL tabs 20mg Angiotensin-II receptor antagonists drug GPRD_product_code
8422001 HYDROCHLOROTHIAZIDE + LOSARTAN tabs 12.5mg + 50mg Angiotensin-II receptor antagonists drug GPRD_product_code
8428001 AMIAS tabs 2mg Angiotensin-II receptor antagonists drug GPRD_product_code
8428002 AMIAS tabs 4mg Angiotensin-II receptor antagonists drug GPRD_product_code
8428003 AMIAS tabs 8mg Angiotensin-II receptor antagonists drug GPRD_product_code
8479001 LOSARTAN tabs 100mg Angiotensin-II receptor antagonists drug GPRD_product_code
8759001 LOSARTAN + HYDROCHLOROTHIAZIDE tabs 50mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
8910001 IRBESARTAN + HYDROCHLOROTHIAZIDE tabs 150mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
8910002 IRBESARTAN + HYDROCHLOROTHIAZIDE tabs 300mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
9210001 COZAAR tabs 100mg Angiotensin-II receptor antagonists drug GPRD_product_code
9450001 MICARDIS PLUS tabs 40mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
9452001 TELMISARTAN + HYDROCHLOROTHIAZIDE tabs 40mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code
9495001 CANDESARTAN tabs 16mg Angiotensin-II receptor antagonists drug GPRD_product_code
9496001 CANDESARTAN tabs 2mg Angiotensin-II receptor antagonists drug GPRD_product_code
9496002 CANDESARTAN tabs 4mg Angiotensin-II receptor antagonists drug GPRD_product_code
9496003 CANDESARTAN tabs 8mg Angiotensin-II receptor antagonists drug GPRD_product_code
9567001 MICARDIS tabs 40mg Angiotensin-II receptor antagonists drug GPRD_product_code
9567002 MICARDIS tabs 80mg Angiotensin-II receptor antagonists drug GPRD_product_code
9567003 MICARDIS tabs 20mg Angiotensin-II receptor antagonists drug GPRD_product_code
9922001 COZAAR-COMP tabs 50mg + 12.5mg Angiotensin-II receptor antagonists drug GPRD_product_code

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH403/version/806/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH403/version/806/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH403', '806', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH403/version/806/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH403/version/806/export/codes/?format=json
CSV site_root/phenotypes/PH403/version/806/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH403', '806', api_client=client)

Version History

Version
ID
Name Owner Publish date
806 Angiotensin-Iireceptorantagonists ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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