Phenotype Library | phenotype: Cholesterol Level

Cholesterol Level

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves

PH411

Version ID

822

Type

Biomarker

Data Sources

CPRD GOLD

Valid event data range

01/01/2000 - 31/12/2007

Sex

♀ Female ♂ Male

Agreement Date

2011-06-28

Coding system

Read codes v2 OXMIS codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.

Publications

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011.

Clinical Code List

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C1749/4636 Cholesterol Level - Primary Care - Read codes v2

Rows: 20

Code	Description	Entity type	Coding System (OXMIS Read)	Category
44OE.		cholesterol_level	Read	test
44OE.00	Plasma total cholesterol level	cholesterol_level	Read	test
44P..		cholesterol_level	Read	test
44P..00	Serum cholesterol	cholesterol_level	Read	test
44P1.00	Serum cholesterol normal	cholesterol_level	Read	test
44P2.00	Serum cholesterol borderline	cholesterol_level	Read	test
44P3.00	Serum cholesterol raised	cholesterol_level	Read	test
44P4.00	Serum cholesterol very high	cholesterol_level	Read	test
44PF.00	Total cholesterol:HDL ratio	cholesterol_level	Read	test
44PG.00	HDL : total cholesterol ratio	cholesterol_level	Read	test
44PH.00	Total cholesterol measurement	cholesterol_level	Read	test
44PJ.00	Serum total cholesterol level	cholesterol_level	Read	test
44PK.00	Serum fasting total cholesterol	cholesterol_level	Read	test
44lF.00	Serum cholesterol/HDL ratio	cholesterol_level	Read	test
44lG.00	Plasma cholesterol/HDL ratio	cholesterol_level	Read	test
44lH.00	Serum cholesterol/LDL ratio	cholesterol_level	Read	test
44lI.00	Plasma cholesterol/LDL ratio	cholesterol_level	Read	test
44lJ.00	Serum cholesterol/VLDL ratio	cholesterol_level	Read	test
44lK.00	Plasma cholesterol/VLDL ratio	cholesterol_level	Read	test
44p3.00	Serum cholesterol raised	cholesterol_level	Read	test

C1750/4638 Cholesterol Level - Primary Care - OXMIS codes

Rows: 9

Code	Description	Entity type	Coding System (OXMIS Read)	Category
L1420	PLASMA CHOLESTEROL LEVEL (mg/dl)	cholesterol_level	OXMIS	test
L1420A	CHOLESTEROL LEVEL (mg/dl)	cholesterol_level	OXMIS	test
L1420B	PLASMA CHOLESTEROL LEVEL (mmol/l)	cholesterol_level	OXMIS	test
L1420H	CHOLESTEROL LEVEL (mg/dl) RAISED	cholesterol_level	OXMIS	test
L1420N	CHOLESTEROL LEVEL (mmol/l) NORMAL	cholesterol_level	OXMIS	test
L1420R	CHOLESTEROL LEVEL (mmol/l) RAISED	cholesterol_level	OXMIS	test
Y060 AV	SCREENING CHOLESTEROL LEVEL	cholesterol_level	OXMIS	test
Y060 BV	SCREENING CHOLESTEROL LEVEL NORMAL	cholesterol_level	OXMIS	test
Y060 CV	SCREENING CHOLESTEROL LEVEL ABNORMAL	cholesterol_level	OXMIS	test

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH411/version/822/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH411/version/822/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH411', '822', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH411/version/822/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH411/version/822/export/codes/?format=json
CSV	site_root/phenotypes/PH411/version/822/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH411', '822', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
822	Cholesterol Level	ieuan.scanlon	2021-10-06	currently shown