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Cholesterol Level

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves

Type
Biomarker
ID
PH411
Version ID
822
Data Sources
Valid event data range
01/01/2000 - 31/12/2007
Sex
Female, Male
Agreement Date
2011-06-28
Coding system
Read codes v2 OXMIS codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.

Publications

  • Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011.

Clinical Code List

Rows: 20
Code Description Entity type Coding System (OXMIS Read) Category
44OE. cholesterol_level Read test
44OE.00 Plasma total cholesterol level cholesterol_level Read test
44P.. cholesterol_level Read test
44P..00 Serum cholesterol cholesterol_level Read test
44P1.00 Serum cholesterol normal cholesterol_level Read test
44P2.00 Serum cholesterol borderline cholesterol_level Read test
44P3.00 Serum cholesterol raised cholesterol_level Read test
44P4.00 Serum cholesterol very high cholesterol_level Read test
44PF.00 Total cholesterol:HDL ratio cholesterol_level Read test
44PG.00 HDL : total cholesterol ratio cholesterol_level Read test
44PH.00 Total cholesterol measurement cholesterol_level Read test
44PJ.00 Serum total cholesterol level cholesterol_level Read test
44PK.00 Serum fasting total cholesterol cholesterol_level Read test
44lF.00 Serum cholesterol/HDL ratio cholesterol_level Read test
44lG.00 Plasma cholesterol/HDL ratio cholesterol_level Read test
44lH.00 Serum cholesterol/LDL ratio cholesterol_level Read test
44lI.00 Plasma cholesterol/LDL ratio cholesterol_level Read test
44lJ.00 Serum cholesterol/VLDL ratio cholesterol_level Read test
44lK.00 Plasma cholesterol/VLDL ratio cholesterol_level Read test
44p3.00 Serum cholesterol raised cholesterol_level Read test
Rows: 9
Code Description Entity type Coding System (OXMIS Read) Category
L1420 PLASMA CHOLESTEROL LEVEL (mg/dl) cholesterol_level OXMIS test
L1420A CHOLESTEROL LEVEL (mg/dl) cholesterol_level OXMIS test
L1420B PLASMA CHOLESTEROL LEVEL (mmol/l) cholesterol_level OXMIS test
L1420H CHOLESTEROL LEVEL (mg/dl) RAISED cholesterol_level OXMIS test
L1420N CHOLESTEROL LEVEL (mmol/l) NORMAL cholesterol_level OXMIS test
L1420R CHOLESTEROL LEVEL (mmol/l) RAISED cholesterol_level OXMIS test
Y060 AV SCREENING CHOLESTEROL LEVEL cholesterol_level OXMIS test
Y060 BV SCREENING CHOLESTEROL LEVEL NORMAL cholesterol_level OXMIS test
Y060 CV SCREENING CHOLESTEROL LEVEL ABNORMAL cholesterol_level OXMIS test

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH411/version/822/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH411/version/822/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH411', '822', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH411/version/822/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH411/version/822/export/codes/?format=json
CSV site_root/phenotypes/PH411/version/822/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH411', '822', api_client=client)

Version History

Version
ID
Name Owner Publish date
822 Cholesterol Level ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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