Phenotype Library | phenotype: Dementia

Dementia

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves

PH417

Version ID

834

Type

Disease or Syndrome

Data Sources

CPRD GOLD

Valid event data range

01/01/2000 - 31/12/2007

Sex

♀ Female ♂ Male

Agreement Date

2011-06-28

Coding system

Read codes v2 OXMIS codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.

Publications

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011.

Clinical Code List

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C1761/4660 Dementia - Primary Care - Read codes v2

Rows: 86

Code	Description	Entity type	Coding System (OXMIS Read)	Category
3AE..00	Global deterioration scale: assessment of prim deg dementia	dementia	Read	diagnostic
66h..00	Dementia monitoring	dementia	Read	diagnostic
6AB..00	Dementia annual review	dementia	Read	diagnostic
E00..00	Senile and presenile organic psychotic conditions	dementia	Read	diagnostic
E00..11	Senile dementia	dementia	Read	diagnostic
E00..12	Senile/presenile dementia	dementia	Read	diagnostic
E000.00	Uncomplicated senile dementia	dementia	Read	diagnostic
E001.00	Presenile dementia	dementia	Read	diagnostic
E001000	Uncomplicated presenile dementia	dementia	Read	diagnostic
E001100	Presenile dementia with delirium	dementia	Read	diagnostic
E001200	Presenile dementia with paranoia	dementia	Read	diagnostic
E001300	Presenile dementia with depression	dementia	Read	diagnostic
E001z00	Presenile dementia NOS	dementia	Read	diagnostic
E002.00	Senile dementia with depressive or paranoid features	dementia	Read	diagnostic
E002000	Senile dementia with paranoia	dementia	Read	diagnostic
E002100	Senile dementia with depression	dementia	Read	diagnostic
E002z00	Senile dementia with depressive or paranoid features NOS	dementia	Read	diagnostic
E003.00	Senile dementia with delirium	dementia	Read	diagnostic
E004.00	Arteriosclerotic dementia	dementia	Read	diagnostic
E004.11	Multi infarct dementia	dementia	Read	diagnostic
E004000	Uncomplicated arteriosclerotic dementia	dementia	Read	diagnostic
E004100	Arteriosclerotic dementia with delirium	dementia	Read	diagnostic
E004200	Arteriosclerotic dementia with paranoia	dementia	Read	diagnostic
E004300	Arteriosclerotic dementia with depression	dementia	Read	diagnostic
E004z00	Arteriosclerotic dementia NOS	dementia	Read	diagnostic
E00y.00	Other senile and presenile organic psychoses	dementia	Read	diagnostic
E00y.11	Presbyophrenic psychosis	dementia	Read	diagnostic
E00z.00	Senile or presenile psychoses NOS	dementia	Read	diagnostic
E012.00	Other alcoholic dementia	dementia	Read	diagnostic
E012.11	Alcoholic dementia NOS	dementia	Read	diagnostic
E012000	Chronic alcoholic brain syndrome	dementia	Read	diagnostic
E041.00	Dementia in conditions EC	dementia	Read	diagnostic
Eu00.00	[X]Dementia in Alzheimer's disease	dementia	Read	diagnostic
Eu00000	[X]Dementia in Alzheimer's disease with early onset	dementia	Read	diagnostic
Eu00011	[X]Presenile dementia;Alzheimer's type	dementia	Read	diagnostic
Eu00012	[X]Primary degen dementia; Alzheimer's type; presenile onset	dementia	Read	diagnostic
Eu00013	[X]Alzheimer's disease type 2	dementia	Read	diagnostic
Eu00100	[X]Dementia in Alzheimer's disease with late onset	dementia	Read	diagnostic
Eu00111	[X]Alzheimer's disease type 1	dementia	Read	diagnostic
Eu00112	[X]Senile dementia;Alzheimer's type	dementia	Read	diagnostic
Eu00113	[X]Primary degen dementia of Alzheimer's type; senile onset	dementia	Read	diagnostic
Eu00200	[X]Dementia in Alzheimer's dis; atypical or mixed type	dementia	Read	diagnostic
Eu00z00	[X]Dementia in Alzheimer's disease; unspecified	dementia	Read	diagnostic
Eu00z11	[X]Alzheimer's dementia unspec	dementia	Read	diagnostic
Eu01.00	[X]Vascular dementia	dementia	Read	diagnostic
Eu01.11	[X]Arteriosclerotic dementia	dementia	Read	diagnostic
Eu01000	[X]Vascular dementia of acute onset	dementia	Read	diagnostic
Eu01100	[X]Multi-infarct dementia	dementia	Read	diagnostic
Eu01111	[X]Predominantly cortical dementia	dementia	Read	diagnostic
Eu01200	[X]Subcortical vascular dementia	dementia	Read	diagnostic
Eu01300	[X]Mixed cortical and subcortical vascular dementia	dementia	Read	diagnostic
Eu01y00	[X]Other vascular dementia	dementia	Read	diagnostic
Eu01z00	[X]Vascular dementia; unspecified	dementia	Read	diagnostic
Eu02.00	[X]Dementia in other diseases classified elsewhere	dementia	Read	diagnostic
Eu02000	[X]Dementia in Pick's disease	dementia	Read	diagnostic
Eu02100	[X]Dementia in Creutzfeldt-Jakob disease	dementia	Read	diagnostic
Eu02200	[X]Dementia in Huntington's disease	dementia	Read	diagnostic
Eu02300	[X]Dementia in Parkinson's disease	dementia	Read	diagnostic
Eu02400	[X]Dementia in human immunodef virus [HIV] disease	dementia	Read	diagnostic
Eu02500	[X]Lewy body dementia	dementia	Read	diagnostic
Eu02y00	[X]Dementia in other specified diseases classif elsewhere	dementia	Read	diagnostic
Eu02z00	[X] Unspecified dementia	dementia	Read	diagnostic
Eu02z11	[X] Presenile dementia NOS	dementia	Read	diagnostic
Eu02z12	[X] Presenile psychosis NOS	dementia	Read	diagnostic
Eu02z13	[X] Primary degenerative dementia NOS	dementia	Read	diagnostic
Eu02z14	[X] Senile dementia NOS	dementia	Read	diagnostic
Eu02z15	[X] Senile psychosis NOS	dementia	Read	diagnostic
Eu02z16	[X] Senile dementia; depressed or paranoid type	dementia	Read	diagnostic
Eu04100	[X]Delirium superimposed on dementia	dementia	Read	diagnostic
Eu10711	[X]Alcoholic dementia NOS	dementia	Read	diagnostic
F110.00	Alzheimer's disease	dementia	Read	diagnostic
F110000	Alzheimer's disease with early onset	dementia	Read	diagnostic
F110100	Alzheimer's disease with late onset	dementia	Read	diagnostic
F111.00	Pick's disease	dementia	Read	diagnostic
F112.00	Senile degeneration of brain	dementia	Read	diagnostic
F116.00	Lewy body disease	dementia	Read	diagnostic
Fyu3000	[X]Other Alzheimer's disease	dementia	Read	diagnostic
ZR1K.00	Alzheimer's disease assessment scale	dementia	Read	diagnostic
ZR1K.11	ADAS - Alzheimer's disease assessment scale	dementia	Read	diagnostic
ZR2X.12	BDRS - Blessed dementia rating scale	dementia	Read	diagnostic
ZR3V.00	Clinical dementia rating scale	dementia	Read	diagnostic
ZR3V.11	DRS - Clinical dementia rating scale	dementia	Read	diagnostic
ZR3V.12	CDR - Clinical dementia rating scale	dementia	Read	diagnostic
ZR3V.13	Dementia rating scale	dementia	Read	diagnostic
ZS7C500	Language disorder of dementia	dementia	Read	diagnostic
e000.00	Uncomplicated senile dementia	dementia	Read	diagnostic

C1762/4662 Dementia - Primary Care - OXMIS codes

Rows: 10

Code	Description	Entity type	Coding System (OXMIS Read)	Category
2900	SENILE DEMENTIA	dementia	OXMIS	diagnostic
2901A	PRESENILE DEMENTIA	dementia	OXMIS	diagnostic
2901B	ALZHEIMER'S DISEASE	dementia	OXMIS	diagnostic
2901D	JACOB- CREUZFELDT DISEASE WITH DEMENTIA	dementia	OXMIS	diagnostic
2919	DEMENTIA ALCOHOLIC	dementia	OXMIS	diagnostic
2930	DEMENTIA ARTERIOSCLEROTIC	dementia	OXMIS	diagnostic
299 B	DEMENTIA	dementia	OXMIS	diagnostic
299 G	DEMENTIA AGGRESSIVE	dementia	OXMIS	diagnostic
Y060 JS	DEMENTIA CLINIC	dementia	OXMIS	diagnostic
Y0601JS	DEMENTIA CLINIC ATTENDANCE	dementia	OXMIS	diagnostic

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH417/version/834/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH417/version/834/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH417', '834', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH417/version/834/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH417/version/834/export/codes/?format=json
CSV	site_root/phenotypes/PH417/version/834/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH417', '834', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
834	Dementia	ieuan.scanlon	2021-10-06	currently shown