Apply modified CALIBER 'Chronic Kidney Disease' algorithm in CPRD primary care data as follows:
A patient is defined as having had CKD stage 3 or above at a specified date:
IF egfr_ckdepi recorded on or before specified date, THEN IF egfr_ckdepi <60 ml/min on the most recent date (index date) before the specified date AND IF egfr_ckdepi <60 ml/min on any date greater than 90 days BEFORE the index date above THEN classify as having CKD3 or above ELSE the patient is not defined as having CKD stage 3 or above.
Where egfr_ckdepi up to and including 31 Dec 2013 is defined as: egfr_ckdepi = 141 * min(crea_gprd * 0.010746 / K, 1)^alpha * max(crea_gprd * 0.010746 / K, 1)^-1.209 * 0.993^age * 1.018 [if female] * 1.159 [if black]
where: alpha = -0.329 for females, -0.411 for males K = 0.7 for females, 0.9 for males
Where egfr_ckdepi from and including 1 Jan 2014 is defined as: egfr_ckdepi = 141 * min(crea_gprd * 0.010746 / K, 1)^alpha * max(crea_gprd * 0.0.011312/ K, 1)^-1.209 * 0.993^age * 1.018 [if female] * 1.159 [if black]
where: alpha = -0.329 for females, -0.411 for males K = 0.7 for females, 0.9 for males
Where crea_gprd is defined as: IF enttype = 165 [Serum creatinine] AND data1 [Operator] = 3 ["="] AND data2 [Value] > 0 THEN crea_gprd = data2
Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3
To Export Phenotype Details:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH42/version/1527/detail/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH42/version/1527/detail/?format=json |
R Package |
|
To Export Phenotype Code List:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH42/version/1527/export/codes/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH42/version/1527/export/codes/?format=json |
CSV | site_root/phenotypes/PH42/version/1527/export/codes/ |
R Package |
|
Version ID |
Name | Owner | Publish date | |
---|---|---|---|---|
1527 | Chronic Kidney Disease | ieuan.scanlon | 2021-10-27 | currently shown |
Export - export all codes into a csv file/JSON/XML for the current phenotype version.
Print - Print page.