Phenotype Library | phenotype: Hypotension Drugs

Hypotension Drugs

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves

PH423

Version ID

846

Type

Drug

Data Sources

CPRD GOLD

Valid event data range

01/01/2000 - 31/12/2007

Sex

♀ Female ♂ Male

Agreement Date

2011-06-28

Coding system

Read codes v2 OXMIS codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.

Publications

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011.

Clinical Code List

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C1772/4682 Hypotension Drugs - Primary Care - Read codes v2

Rows: 39

Code	Description	Entity type	Coding System (OXMIS Read)	Category
23D2.11	O/E - bronchospasm	hypotension drugs	Read	drug
2422.00	O/E - pulse rate - bradycardia	hypotension drugs	Read	drug
2422.11	O/E - bradycardia	hypotension drugs	Read	drug
8624.00	Hypothermia with hypotension	hypotension drugs	Read	drug
B540.11	Phaeochromocytoma	hypotension drugs	Read	drug
B7H0000	Benign phaeochromocytoma	hypotension drugs	Read	drug
BBD9.00	[M]Phaeochromocytoma NOS	hypotension drugs	Read	drug
BBDA.00	[M]Phaeochromocytoma; malignant	hypotension drugs	Read	drug
C362000	Metabolic acidosis NEC	hypotension drugs	Read	drug
F130300	Parkinsonism with orthostatic hypotension	hypotension drugs	Read	drug
G331.00	Prinzmetal's angina	hypotension drugs	Read	drug
G57y000	Persistent sinus bradycardia	hypotension drugs	Read	drug
G57y100	Severe sinus bradycardia	hypotension drugs	Read	drug
G57y300	Sick sinus syndrome	hypotension drugs	Read	drug
G87..00	Hypotension	hypotension drugs	Read	drug
G870.00	Orthostatic hypotension	hypotension drugs	Read	drug
G870.11	Postural hypotension	hypotension drugs	Read	drug
G871.00	Chronic hypotension	hypotension drugs	Read	drug
G872.00	Idiopathic hypotension	hypotension drugs	Read	drug
G873.00	Hypotension due to drugs	hypotension drugs	Read	drug
G87z.00	Hypotension NOS	hypotension drugs	Read	drug
Gyu9000	[X]Other hypotension	hypotension drugs	Read	drug
H061200	Acute bronchiolitis with bronchospasm	hypotension drugs	Read	drug
H5y1600	Bronchospasm	hypotension drugs	Read	drug
L263.12	Fetal bradycardia	hypotension drugs	Read	drug
L263A00	Maternal care for fetal bradycardia during pregnancy	hypotension drugs	Read	drug
L392.00	Maternal hypotension syndrome	hypotension drugs	Read	drug
L392000	Maternal hypotension syndrome unspecified	hypotension drugs	Read	drug
L392100	Maternal hypotension syndrome - delivered	hypotension drugs	Read	drug
L392200	Maternal hypotension syndrome - delivered with p/n problem	hypotension drugs	Read	drug
L392300	Maternal hypotension syndrome with antenatal problem	hypotension drugs	Read	drug
L392400	Maternal hypotension syndrome with postnatal problem	hypotension drugs	Read	drug
L392z00	Maternal hypotension syndrome NOS	hypotension drugs	Read	drug
Q448.00	Newborn late metabolic acidosis	hypotension drugs	Read	drug
Q48C.00	Neonatal hypotension	hypotension drugs	Read	drug
R055100	[D]Cardiogenic shock	hypotension drugs	Read	drug
R059.00	[D]Sinus bradycardia	hypotension drugs	Read	drug
R05W.00	[D] Bradycardia; unspecified	hypotension drugs	Read	drug
Ryu0600	[X]Bradycardia; unspecified	hypotension drugs	Read	drug

C1773/4684 Hypotension Drugs - Primary Care - OXMIS codes

Rows: 13

Code	Description	Entity type	Coding System (OXMIS Read)	Category
2552	PHAEOCHROMOCYTOMA	hypotension drugs	OXMIS	drug
4139PB	PRINZMETAL'S ANGINA	hypotension drugs	OXMIS	drug
4279BR	SINUS BRADYCARDIA	hypotension drugs	OXMIS	drug
4279G	BRADYCARDIA	hypotension drugs	OXMIS	drug
4279PK	SICK SINUS SYNDROME	hypotension drugs	OXMIS	drug
4580	HYPOTENSION	hypotension drugs	OXMIS	drug
4580A	POSTURAL HYPOTENSION	hypotension drugs	OXMIS	drug
4580AB	HYPOTENSION FIRST DOSE	hypotension drugs	OXMIS	drug
4580T	HYPOTENSION ORTHOSTATIC	hypotension drugs	OXMIS	drug
5199AL	BRONCHOSPASM ALLERGIC	hypotension drugs	OXMIS	drug
5199B	BRONCHOSPASM	hypotension drugs	OXMIS	drug
7886M	METABOLIC ACIDOSIS	hypotension drugs	OXMIS	drug
9779PH	HYPOTENSION POSTURAL DRUG INDUCED	hypotension drugs	OXMIS	drug

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH423/version/846/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH423/version/846/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH423', '846', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH423/version/846/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH423/version/846/export/codes/?format=json
CSV	site_root/phenotypes/PH423/version/846/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH423', '846', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
846	Hypotension Drugs	ieuan.scanlon	2021-10-06	currently shown