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Serious Mental Illness (SMI) Drugs

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves

Type
Drug
ID
PH435
Version ID
870
Data Sources
Valid event data range
01/01/2000 - 31/12/2007
Sex
Female, Male
Agreement Date
2011-06-28
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.

Publications

  • Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011.

Clinical Code List

Rows: 23
Code Description Entity type Category Coding System (GPRD_product_code)
1185001 CAMCOLIT 400 tabs SMI drugs drug GPRD_product_code
141001 CAMCOLIT 250 tabs SMI drugs drug GPRD_product_code
2020009 LITHIUM CARBONATE mr tab 400mg [APS] SMI drugs drug GPRD_product_code
2283001 LITHIUM CITRATE oral liq 1.018g/5ml SMI drugs drug GPRD_product_code
2294001 LI-LIQUID soln 509mg/5ml SMI drugs drug GPRD_product_code
2294002 LI-LIQUID soln 1.018g/5ml SMI drugs drug GPRD_product_code
2325007 LITHIUM 250 MG CAP SMI drugs drug GPRD_product_code
2465001 LITAREX CR tablets 564mg SMI drugs drug GPRD_product_code
3134007 LITHIUM 10.8 MMOLS/5MLS LIQ SMI drugs drug GPRD_product_code
3995001 LITHIUM CARBONATE mr tab 200mg SMI drugs drug GPRD_product_code
3995002 LITHIUM CARBONATE tabs 250mg SMI drugs drug GPRD_product_code
3995003 LITHIUM CARBONATE mr tab 300mg SMI drugs drug GPRD_product_code
3996001 LITHIUM CARBONATE mr tab 400mg SMI drugs drug GPRD_product_code
3997001 LITHIUM CARBONATE mr tab 450mg SMI drugs drug GPRD_product_code
3998001 PHASAL tabs 300mg SMI drugs drug GPRD_product_code
3999001 LITHIUM CITRATE mr tab 564mg SMI drugs drug GPRD_product_code
3999002 LITHIUM CITRATE sf liq 520mg/5ml SMI drugs drug GPRD_product_code
3999003 LITHIUM CITRATE oral liq 509mg/5ml SMI drugs drug GPRD_product_code
534001 LISKONUM tabs 450mg SMI drugs drug GPRD_product_code
6587001 PRIADEL liq 520mg/5ml SMI drugs drug GPRD_product_code
7457001 LITHONATE sr tab 400mg SMI drugs drug GPRD_product_code
782001 PRIADEL tabs 200mg SMI drugs drug GPRD_product_code
782002 PRIADEL tabs 400mg SMI drugs drug GPRD_product_code

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH435/version/870/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH435/version/870/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH435', '870', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH435/version/870/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH435/version/870/export/codes/?format=json
CSV site_root/phenotypes/PH435/version/870/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH435', '870', api_client=client)

Version History

Version
ID
Name Owner Publish date
870 Serious Mental Illness (SMI) Drugs ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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