Phenotype Library | phenotype: Sulphonylureas

Sulphonylureas

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves

PH440

Version ID

880

Type

Drug

Data Sources

CPRD GOLD

Valid event data range

01/01/2000 - 31/12/2007

Sex

♀ Female ♂ Male

Agreement Date

2011-06-28

Coding system

GPRD product codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

Patient level data were extracted from the General Practice Research Database (GPRD), which contains anonymised, patient based data on morbidity, prescribing, treatment, and referral collected from over 500 general practices, covering about 7% of the UK population (4.4 million patients).14 Data are in Read code format—a hierarchical system used to code clinical data. Additional data on prescriptions and test results are available as free-text entries. We selected a sample of 148 practices that provided data to the GPRD continuously between January 2000 and December 2007, structured to include a range of list (patient panel) sizes. Selected practices were nationally representative in terms of patient sex and age distribution and area socioeconomic deprivation but had a relatively large average list size, reflecting a bias towards larger practices in the GPRD. Overall, the selected practices performed marginally better than national practices on the clinical indicators in the Quality and Outcomes Framework. A random selection of 4500 patients registered for at least one day between 1 January 2000 and 31 December 2007 was drawn from each practice. For practices with fewer than 4501 patients, all patients were selected. The final sample consisted of 653 500 patients. Patients with relevant conditions were identified from their diagnostic Read codes. Patients for whom targets were met were identified from the relevant Read codes and free-text terms.

Publications

Tim Doran, Evangelos Kontopantelis, Jose M Valderas, Stephen Campbell, Martin Roland, Chris Salisbury, David Reeves, Effect of financial incentives on incentivised and non-incentivised clinical activities: longitudinal analysis of data from the UK Quality and Outcomes Framework. BMJ, 342:d3590, 2011.

Clinical Code List

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C1798/4734 Sulphonylureas - Primary Care - GPRD product codes

Rows: 55

Code	Description	Entity type	Category	Coding System (GPRD_product_code)
1335009	glibenclamide tabs 5mg [aps]	sulphonylureas	drug	GPRD_product_code
1335010	glibenclamide tabs 2.5mg [aps]	sulphonylureas	drug	GPRD_product_code
1356009	glibenclamide tabs 5mg [berk]	sulphonylureas	drug	GPRD_product_code
1356010	glibenclamide tabs 2.5mg [berk]	sulphonylureas	drug	GPRD_product_code
14098001	glibenclamide oral susp 5mg/5ml	sulphonylureas	drug	GPRD_product_code
1451009	glibenclamide tabs 5mg [numark]	sulphonylureas	drug	GPRD_product_code
14734001	glibenclamide oral liq	sulphonylureas	drug	GPRD_product_code
1581009	glibenclamide tabs 2.5mg [lagap]	sulphonylureas	drug	GPRD_product_code
1581010	glibenclamide tabs 5mg [lagap]	sulphonylureas	drug	GPRD_product_code
1811009	chlorpropamide tabs 100mg [aps]	sulphonylureas	drug	GPRD_product_code
1811010	chlorpropamide tabs 250mg [aps]	sulphonylureas	drug	GPRD_product_code
212001	daonil tabs 5mg	sulphonylureas	drug	GPRD_product_code
2224009	chlorpropamide tabs 100mg [alphar/cox]	sulphonylureas	drug	GPRD_product_code
2224010	chlorpropamide tabs 250mg [alphar/cox]	sulphonylureas	drug	GPRD_product_code
2248009	glibenclamide tabs 2.5mg [alphar/cox]	sulphonylureas	drug	GPRD_product_code
2248010	glibenclamide tabs 5mg [alphar/cox]	sulphonylureas	drug	GPRD_product_code
235001	diabinese tabs 100mg	sulphonylureas	drug	GPRD_product_code
235002	diabinese tabs 250mg	sulphonylureas	drug	GPRD_product_code
2416001	libanil tabs 2.5mg	sulphonylureas	drug	GPRD_product_code
2416002	libanil tabs 5mg	sulphonylureas	drug	GPRD_product_code
2447009	glibenclamide tabs 2.5mg [ivax]	sulphonylureas	drug	GPRD_product_code
2447010	glibenclamide tabs 5mg [ivax]	sulphonylureas	drug	GPRD_product_code
2462001	diabetamide tabs 2.5mg	sulphonylureas	drug	GPRD_product_code
2462002	diabetamide tabs 5mg	sulphonylureas	drug	GPRD_product_code
2866007	chloropropamide 500 mg tab	sulphonylureas	drug	GPRD_product_code
2872001	glibenclamide tabs 2.5mg	sulphonylureas	drug	GPRD_product_code
2872002	glibenclamide tabs 5mg	sulphonylureas	drug	GPRD_product_code
2902001	malix tabs 2.5mg	sulphonylureas	drug	GPRD_product_code
2902002	malix tabs 5mg	sulphonylureas	drug	GPRD_product_code
2942001	calabren tabs 5mg	sulphonylureas	drug	GPRD_product_code
2942002	calabren tabs 2.5mg	sulphonylureas	drug	GPRD_product_code
3244001	chlorpropamide tabs 100mg	sulphonylureas	drug	GPRD_product_code
3244002	chlorpropamide tabs 250mg	sulphonylureas	drug	GPRD_product_code
331001	euglucon tabs 2.5mg	sulphonylureas	drug	GPRD_product_code
331002	euglucon tabs 5mg	sulphonylureas	drug	GPRD_product_code
3312001	glymese tabs 250mg	sulphonylureas	drug	GPRD_product_code
3384009	chlorpropamide tabs 100mg [sussex]	sulphonylureas	drug	GPRD_product_code
3384010	chlorpropamide tabs 250mg [sussex]	sulphonylureas	drug	GPRD_product_code
3440009	glibenclamide tabs 2.5mg [kent]	sulphonylureas	drug	GPRD_product_code
3778009	glibenclamide tabs 2.5mg [gen (uk)]	sulphonylureas	drug	GPRD_product_code
3779009	glibenclamide tabs 5mg [gen (uk)]	sulphonylureas	drug	GPRD_product_code
417009	glibenclamide tabs 5mg [cp pharm]	sulphonylureas	drug	GPRD_product_code
417010	glibenclamide tabs 2.5mg [cp pharm]	sulphonylureas	drug	GPRD_product_code
418009	glibenclamide tabs 2.5mg [celltech]	sulphonylureas	drug	GPRD_product_code
418010	glibenclamide tabs 5mg [celltech]	sulphonylureas	drug	GPRD_product_code
419009	glibenclamide tabs 5mg [hillcross]	sulphonylureas	drug	GPRD_product_code
419010	glibenclamide tabs 2.5mg [hillcross]	sulphonylureas	drug	GPRD_product_code
4398009	glibenclamide tabs 5mg [kent]	sulphonylureas	drug	GPRD_product_code
7481001	grenamide tabs 2.5mg	sulphonylureas	drug	GPRD_product_code
7481002	grenamide tabs 5mg	sulphonylureas	drug	GPRD_product_code
752009	chlorpropamide tabs 100mg [cp pharm]	sulphonylureas	drug	GPRD_product_code
752010	chlorpropamide tabs 250mg [cp pharm]	sulphonylureas	drug	GPRD_product_code
753009	chlorpropamide tabs 100mg [celltech]	sulphonylureas	drug	GPRD_product_code
753010	chlorpropamide tabs 250mg [celltech]	sulphonylureas	drug	GPRD_product_code
854001	semi-daonil tabs 2.5mg	sulphonylureas	drug	GPRD_product_code

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH440/version/880/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH440/version/880/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH440', '880', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH440/version/880/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH440/version/880/export/codes/?format=json
CSV	site_root/phenotypes/PH440/version/880/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH440', '880', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
880	Sulphonylureas	ieuan.scanlon	2021-10-06	currently shown