A cohort study based on primary care data from the QResearch database will include patients with one of the three common tumours: breast, bowel and prostate. The primary outcome will be overall survival from the date of cancer diagnosis. Cox proportional hazards regression will be used to compare the survival of patients with cancer taking VGSC-inhibiting drugs (including anticonvulsants and class I antiarrhythmic agents) with patients with cancer not exposed to these drugs, adjusting for age and sex. Exposure to VGSC-inhibiting drugs will be defined as having at least one prescription for these drugs prior to cancer diagnosis. High and low exposure groups will be identified based on the length of use. A number of sensitivity and secondary analyses will be conducted.
Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenburry, Exposure to sodium channel-inhibiting drugs and cancer survival protocol for a cohort study using the QResearch primary care database. BMJ Open, 4:e006604 2014.
| Code | Description | Entity type | Category | Coding System (Read) |
|---|---|---|---|---|
| 136 | Alcohol consumption | res17: Alcohol status | test | Read |
| 1361 | Teetotaller | res17: Alcohol status | test | Read |
| 1361-1 | Non drinker alcohol | res17: Alcohol status | test | Read |
| 1361-2 | Non-drinker alcohol | res17: Alcohol status | test | Read |
| 1362 | Trivial drinker - <1u/day | res17: Alcohol status | test | Read |
| 1362-1 | Drinks rarely | res17: Alcohol status | test | Read |
| 1362-2 | Drinks occasionally | res17: Alcohol status | test | Read |
| 1363 | Light drinker - 1-2u/day | res17: Alcohol status | test | Read |
| 1364 | Moderate drinker - 3-6u/day | res17: Alcohol status | test | Read |
| 1365 | Heavy drinker - 7-9u/day | res17: Alcohol status | test | Read |
| 1366 | Very heavy drinker - >9u/day | res17: Alcohol status | test | Read |
| 1367 | Stopped drinking alcohol | res17: Alcohol status | test | Read |
| 1368 | Alcohol consumption unknown | res17: Alcohol status | test | Read |
| 1369 | Suspect alcohol abuse - denied | res17: Alcohol status | test | Read |
| 136A | Ex-trivial drinker (<1u/day) | res17: Alcohol status | test | Read |
| 136B | Ex-light drinker - (1-2u/day) | res17: Alcohol status | test | Read |
| 136C | Ex-moderate drinker - (3-6u/d) | res17: Alcohol status | test | Read |
| 136D | Ex-heavy drinker - (7-9u/day) | res17: Alcohol status | test | Read |
| 136E | Ex-very heavy drinker-(>9u/d) | res17: Alcohol status | test | Read |
| 136F | Spirit drinker | res17: Alcohol status | test | Read |
| 136G | Beer drinker | res17: Alcohol status | test | Read |
| 136H | Drinks beer and spirits | res17: Alcohol status | test | Read |
| 136I | Drinks wine | res17: Alcohol status | test | Read |
| 136J | Social drinker | res17: Alcohol status | test | Read |
| 136K | Alcohol intake above recommended sensible limits | res17: Alcohol status | test | Read |
| 136L | Alcohol intake within recommended sensible limits | res17: Alcohol status | test | Read |
| 136M | Current non drinker | res17: Alcohol status | test | Read |
| 136N | Light drinker | res17: Alcohol status | test | Read |
| 136O | Moderate drinker | res17: Alcohol status | test | Read |
| 136P | Heavy drinker | res17: Alcohol status | test | Read |
| 136Q | Very heavy drinker | res17: Alcohol status | test | Read |
| 136R | Binge drinker | res17: Alcohol status | test | Read |
| 136S | Hazardous alcohol use | res17: Alcohol status | test | Read |
| 136T | Harmful alcohol use | res17: Alcohol status | test | Read |
| 136V | Alcohol units per week | res17: Alcohol status | test | Read |
| 136X | Alcohol units consumed on heaviest drinking day | res17: Alcohol status | test | Read |
| 136Y | Drinks in morning to get rid of hangover | res17: Alcohol status | test | Read |
| 136Z | Alcohol consumption NOS | res17: Alcohol status | test | Read |
| 136a | Increasing risk drinking | res17: Alcohol status | test | Read |
| 136b | Feels should cut down drinking | res17: Alcohol status | test | Read |
| 136c | Higher risk drinking | res17: Alcohol status | test | Read |
| 136d | Lower risk drinking | res17: Alcohol status | test | Read |
| 136e | Declines to state current alcohol consumption | res17: Alcohol status | test | Read |
| E23-2 | Alcohol problem drinking | res17: Alcohol status | test | Read |
| EGTON418 | Alcohol intake | res17: Alcohol status | test | Read |
| EGTONGR6 | Grade A none drinker or rare | res17: Alcohol status | test | Read |
| EGTONGR7 | Grade B 0-20 units/week | res17: Alcohol status | test | Read |
| EGTONGR8 | Grade C 21-49 units/week | res17: Alcohol status | test | Read |
| EGTONGR9 | Grade D 50 or more units/week | res17: Alcohol status | test | Read |
| EMISNQUN23 | Unsuccessful attempts to reduce alcohol consumption | res17: Alcohol status | test | Read |
| EMISQAL1 | Alcohol AUDIT score | res17: Alcohol status | test | Read |
| EMISQAL2 | Alcohol reduction-maintain abstinence | res17: Alcohol status | test | Read |
| EMISQAU1 | AUDIT score <4 no drinking problem | res17: Alcohol status | test | Read |
| EMISQAU2 | AUDIT score >5 alcohol dependence syndrome | res17: Alcohol status | test | Read |
| EMISQAU3 | AUDIT score >5 alcohol problem drinker | res17: Alcohol status | test | Read |
| EMISQNO6 | Not interested in reducing alcohol | res17: Alcohol status | test | Read |
| EMISQOT3 | Other alcohol related information | res17: Alcohol status | test | Read |
| EMISQRE13 | Ready to start reducing alcohol | res17: Alcohol status | test | Read |
| EMISQTH4 | Thinking about reducing alcohol | res17: Alcohol status | test | Read |
To Export Phenotype Details:
| Format | API |
|---|---|
| XML | site_root/api/v1/public/phenotypes/PH447/version/894/detail/?format=xml |
| JSON | site_root/api/v1/public/phenotypes/PH447/version/894/detail/?format=json |
| R Package |
|
To Export Phenotype Code List:
| Format | API |
|---|---|
| XML | site_root/api/v1/public/phenotypes/PH447/version/894/export/codes/?format=xml |
| JSON | site_root/api/v1/public/phenotypes/PH447/version/894/export/codes/?format=json |
| CSV | site_root/phenotypes/PH447/version/894/export/codes/ |
| R Package |
|
| Version ID |
Name | Owner | Publish date | |
|---|---|---|---|---|
| 894 | Alcohol Status | ieuan.scanlon | 2021-10-06 | currently shown |
Export - export all codes into a csv file/JSON/XML for the current phenotype version.
Print - Print page.