A cohort study based on primary care data from the QResearch database will include patients with one of the three common tumours: breast, bowel and prostate. The primary outcome will be overall survival from the date of cancer diagnosis. Cox proportional hazards regression will be used to compare the survival of patients with cancer taking VGSC-inhibiting drugs (including anticonvulsants and class I antiarrhythmic agents) with patients with cancer not exposed to these drugs, adjusting for age and sex. Exposure to VGSC-inhibiting drugs will be defined as having at least one prescription for these drugs prior to cancer diagnosis. High and low exposure groups will be identified based on the length of use. A number of sensitivity and secondary analyses will be conducted.
Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenburry, Exposure to sodium channel-inhibiting drugs and cancer survival protocol for a cohort study using the QResearch primary care database. BMJ Open, 4:e006604 2014.
Code | Description | Entity type | Category | Coding System (Read) |
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22K | Body Mass Index | res17: BMI | test | Read |
22K1 | Body Mass Index normal K/M2 | res17: BMI | test | Read |
22K2 | Body Mass Index high K/M2 | res17: BMI | test | Read |
22K3 | Body Mass Index low K/M2 | res17: BMI | test | Read |
22K4 | Body mass index index 25-29 - overweight | res17: BMI | test | Read |
22K5 | Body mass index 30+ - obesity | res17: BMI | test | Read |
22K6 | Body mass index less than 20 | res17: BMI | test | Read |
22K7 | Body mass index 40+ - severely obese | res17: BMI | test | Read |
22K8 | Body mass index 20-24 - normal | res17: BMI | test | Read |
22K9 | Body mass index centile | res17: BMI | test | Read |
22K90 | Baseline body mass index centile | res17: BMI | test | Read |
22KA | Target body mass index | res17: BMI | test | Read |
22KB | Baseline body mass index | res17: BMI | test | Read |
EMISNQBM1 | BMI centile | res17: BMI | test | Read |
EMISNQBO29 | Body mass index less than 18.5 | res17: BMI | test | Read |
EMISNQTA9 | Target body mass index | res17: BMI | test | Read |
JHCBO5 | Body mass index 18.5-24.9 | res17: BMI | test | Read |
PCNQBO1 | Body mass index | res17: BMI | test | Read |
To Export Phenotype Details:
Format | API |
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XML | site_root/api/v1/public/phenotypes/PH448/version/896/detail/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH448/version/896/detail/?format=json |
R Package |
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To Export Phenotype Code List:
Format | API |
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XML | site_root/api/v1/public/phenotypes/PH448/version/896/export/codes/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH448/version/896/export/codes/?format=json |
CSV | site_root/phenotypes/PH448/version/896/export/codes/ |
R Package |
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Version ID |
Name | Owner | Publish date | |
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896 | BMI | ieuan.scanlon | 2021-10-06 | currently shown |
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