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Breast Cancer

Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenbury

Type
Disease or Syndrome
ID
PH450
Version ID
900
Data Sources
QResearch
Valid event data range
01/01/1998 - 31/12/2013
Sex
Female, Male
Agreement Date
2014-11-14
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

A cohort study based on primary care data from the QResearch database will include patients with one of the three common tumours: breast, bowel and prostate. The primary outcome will be overall survival from the date of cancer diagnosis. Cox proportional hazards regression will be used to compare the survival of patients with cancer taking VGSC-inhibiting drugs (including anticonvulsants and class I antiarrhythmic agents) with patients with cancer not exposed to these drugs, adjusting for age and sex. Exposure to VGSC-inhibiting drugs will be defined as having at least one prescription for these drugs prior to cancer diagnosis. High and low exposure groups will be identified based on the length of use. A number of sensitivity and secondary analyses will be conducted.

Publications

  • Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenburry, Exposure to sodium channel-inhibiting drugs and cancer survival protocol for a cohort study using the QResearch primary care database. BMJ Open, 4:e006604 2014.

Clinical Code List

Rows: 48
Code Description Entity type Category Coding System (Read)
B34 Malignant neoplasm of female breast res17: Breast cancer diagnostic Read
B34-1 Ca female breast res17: Breast cancer diagnostic Read
B34-98 Ca breast - NOS res17: Breast cancer diagnostic Read
B34-99 Carcinoma breast res17: Breast cancer diagnostic Read
B340 Malignant neoplasm of nipple and areola of female breast res17: Breast cancer diagnostic Read
B340-99 Ca breast - nipple/central res17: Breast cancer diagnostic Read
B3400 Malignant neoplasm of nipple of female breast res17: Breast cancer diagnostic Read
B3401 Malignant neoplasm of areola of female breast res17: Breast cancer diagnostic Read
B340z Malignant neoplasm of nipple or areola of female breast NOS res17: Breast cancer diagnostic Read
B341 Malignant neoplasm of central part of female breast res17: Breast cancer diagnostic Read
B342 Malignant neoplasm of upper-inner quadrant of female breast res17: Breast cancer diagnostic Read
B342-99 Ca breast-upper,inner quadrant res17: Breast cancer diagnostic Read
B343 Malignant neoplasm of lower-inner quadrant of female breast res17: Breast cancer diagnostic Read
B343-99 Ca breast-lower,inner quadrant res17: Breast cancer diagnostic Read
B344 Malignant neoplasm of upper-outer quadrant of female breast res17: Breast cancer diagnostic Read
B344-99 Ca breast-upper,outer quadrant res17: Breast cancer diagnostic Read
B345 Malignant neoplasm of lower-outer quadrant of female breast res17: Breast cancer diagnostic Read
B345-99 Ca breast-lower,outer quadrant res17: Breast cancer diagnostic Read
B346 Malignant neoplasm of axillary tail of female breast res17: Breast cancer diagnostic Read
B346-99 Ca breast - axillary tail res17: Breast cancer diagnostic Read
B347 Malignant neoplasm, overlapping lesion of breast res17: Breast cancer diagnostic Read
B34y Malignant neoplasm of other site of female breast res17: Breast cancer diagnostic Read
B34y0 Malignant neoplasm of ectopic site of female breast res17: Breast cancer diagnostic Read
B34yz Malignant neoplasm of other site of female breast NOS res17: Breast cancer diagnostic Read
B34z Malignant neoplasm of female breast NOS res17: Breast cancer diagnostic Read
B34z-99 Ca breast - NOS res17: Breast cancer diagnostic Read
B35 Malignant neoplasm of male breast res17: Breast cancer diagnostic Read
B35-99 Ca breast - male res17: Breast cancer diagnostic Read
B350 Malignant neoplasm of nipple and areola of male breast res17: Breast cancer diagnostic Read
B3500 Malignant neoplasm of nipple of male breast res17: Breast cancer diagnostic Read
B3501 Malignant neoplasm of areola of male breast res17: Breast cancer diagnostic Read
B350z Malignant neoplasm of nipple or areola of male breast NOS res17: Breast cancer diagnostic Read
B35z Malignant neoplasm of other site of male breast res17: Breast cancer diagnostic Read
B35z0 Malignant neoplasm of ectopic site of male breast res17: Breast cancer diagnostic Read
B35zz Malignant neoplasm of male breast NOS res17: Breast cancer diagnostic Read
B36 Local recurrence of malignant tumour of breast res17: Breast cancer diagnostic Read
B58y0 Secondary malignant neoplasm of breast res17: Breast cancer diagnostic Read
B830 Carcinoma in situ of breast res17: Breast cancer diagnostic Read
B830-99 Carcinoma in situ breast res17: Breast cancer diagnostic Read
B8300 Lobular carcinoma in situ of breast res17: Breast cancer diagnostic Read
B8301 Intraductal carcinoma in situ of breast res17: Breast cancer diagnostic Read
B933 Neoplasm of uncertain behaviour of breast res17: Breast cancer diagnostic Read
BA03 Neoplasm of unspecified nature of breast res17: Breast cancer diagnostic Read
BB94-1 [M]Secretory breast carcinoma res17: Breast cancer diagnostic Read
Byu6 [X]Malignant neoplasm of breast res17: Breast cancer diagnostic Read
EMISNQLO13 Local recurrence of malignant tumour of breast res17: Breast cancer diagnostic Read
HNG0190 [RFC] Breast cancer res17: Breast cancer diagnostic Read
ZV103 [V]Personal history of malignant neoplasm of breast res17: Breast cancer diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH450/version/900/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH450/version/900/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH450', '900', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH450/version/900/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH450/version/900/export/codes/?format=json
CSV site_root/phenotypes/PH450/version/900/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH450', '900', api_client=client)

Version History

Version
ID
Name Owner Publish date
900 Breast Cancer ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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