A cohort study based on primary care data from the QResearch database will include patients with one of the three common tumours: breast, bowel and prostate. The primary outcome will be overall survival from the date of cancer diagnosis. Cox proportional hazards regression will be used to compare the survival of patients with cancer taking VGSC-inhibiting drugs (including anticonvulsants and class I antiarrhythmic agents) with patients with cancer not exposed to these drugs, adjusting for age and sex. Exposure to VGSC-inhibiting drugs will be defined as having at least one prescription for these drugs prior to cancer diagnosis. High and low exposure groups will be identified based on the length of use. A number of sensitivity and secondary analyses will be conducted.
Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenburry, Exposure to sodium channel-inhibiting drugs and cancer survival protocol for a cohort study using the QResearch primary care database. BMJ Open, 4:e006604 2014.
| Code | Description | Entity type | Category | Coding System (Read) |
|---|---|---|---|---|
| B13 | Malignant neoplasm of colon | res17: Colorectal cancer | diagnostic | Read |
| B130 | Malignant neoplasm of hepatic flexure of colon | res17: Colorectal cancer | diagnostic | Read |
| B130-99 | Ca hepatic flexure - colon | res17: Colorectal cancer | diagnostic | Read |
| B131 | Malignant neoplasm of transverse colon | res17: Colorectal cancer | diagnostic | Read |
| B131-99 | Ca transverse colon | res17: Colorectal cancer | diagnostic | Read |
| B132 | Malignant neoplasm of descending colon | res17: Colorectal cancer | diagnostic | Read |
| B132-99 | Ca descending colon | res17: Colorectal cancer | diagnostic | Read |
| B133 | Malignant neoplasm of sigmoid colon | res17: Colorectal cancer | diagnostic | Read |
| B133-99 | Ca sigmoid colon | res17: Colorectal cancer | diagnostic | Read |
| B134 | Malignant neoplasm of caecum | res17: Colorectal cancer | diagnostic | Read |
| B134-1 | Carcinoma of caecum | res17: Colorectal cancer | diagnostic | Read |
| B135 | Malignant neoplasm of appendix | res17: Colorectal cancer | diagnostic | Read |
| B136 | Malignant neoplasm of ascending colon | res17: Colorectal cancer | diagnostic | Read |
| B136-99 | Ca ascending colon | res17: Colorectal cancer | diagnostic | Read |
| B137 | Malignant neoplasm of splenic flexure of colon | res17: Colorectal cancer | diagnostic | Read |
| B137-99 | Ca splenic flexure - colon | res17: Colorectal cancer | diagnostic | Read |
| B138 | Malignant neoplasm, overlapping lesion of colon | res17: Colorectal cancer | diagnostic | Read |
| B139 | Hereditary nonpolyposis colon cancer | res17: Colorectal cancer | diagnostic | Read |
| B13y | Malignant neoplasm of other specified sites of colon | res17: Colorectal cancer | diagnostic | Read |
| B13z | Malignant neoplasm of colon NOS | res17: Colorectal cancer | diagnostic | Read |
| B13z-1 | Colonic cancer | res17: Colorectal cancer | diagnostic | Read |
| B14 | Malignant neoplasm of rectum, rectosigmoid junction and anus | res17: Colorectal cancer | diagnostic | Read |
| B14-99 | Ca rectum + Ca anus | res17: Colorectal cancer | diagnostic | Read |
| B140 | Malignant neoplasm of rectosigmoid junction | res17: Colorectal cancer | diagnostic | Read |
| B140-99 | Ca rectosigmoid junction | res17: Colorectal cancer | diagnostic | Read |
| B141 | Malignant neoplasm of rectum | res17: Colorectal cancer | diagnostic | Read |
| B141-1 | Carcinoma of rectum | res17: Colorectal cancer | diagnostic | Read |
| B141-2 | Rectal carcinoma | res17: Colorectal cancer | diagnostic | Read |
| B141-99 | Adenocarcinoma of rectum | res17: Colorectal cancer | diagnostic | Read |
| B1420 | Malignant neoplasm of cloacogenic zone | res17: Colorectal cancer | diagnostic | Read |
| B143 | Malignant neoplasm of anus unspecified | res17: Colorectal cancer | diagnostic | Read |
| B14y | Malig neop other site rectum, rectosigmoid junction and anus | res17: Colorectal cancer | diagnostic | Read |
| B14z | Malignant neoplasm rectum,rectosigmoid junction and anus NOS | res17: Colorectal cancer | diagnostic | Read |
| B14z-99 | Ca rectum + Ca anus NOS | res17: Colorectal cancer | diagnostic | Read |
| B1z0-1 | Cancer of bowel | res17: Colorectal cancer | diagnostic | Read |
| B575 | Secondary malignant neoplasm of large intestine and rectum | res17: Colorectal cancer | diagnostic | Read |
| B5750 | Secondary malignant neoplasm of colon | res17: Colorectal cancer | diagnostic | Read |
| B5751 | Secondary malignant neoplasm of rectum | res17: Colorectal cancer | diagnostic | Read |
| B575z | Secondary malig neop of large intestine or rectum NOS | res17: Colorectal cancer | diagnostic | Read |
| B803 | Carcinoma in situ of colon | res17: Colorectal cancer | diagnostic | Read |
| B8030 | Carcinoma in situ of hepatic flexure of colon | res17: Colorectal cancer | diagnostic | Read |
| B8031 | Carcinoma in situ of transverse colon | res17: Colorectal cancer | diagnostic | Read |
| B8032 | Carcinoma in situ of descending colon | res17: Colorectal cancer | diagnostic | Read |
| B8033 | Carcinoma in situ of sigmoid colon | res17: Colorectal cancer | diagnostic | Read |
| B8036 | Carcinoma in situ of ascending colon | res17: Colorectal cancer | diagnostic | Read |
| B8037 | Carcinoma in situ of splenic flexure of colon | res17: Colorectal cancer | diagnostic | Read |
| B8038 | High grade dysplasia of colon | res17: Colorectal cancer | diagnostic | Read |
| B803z | Carcinoma in situ of colon NOS | res17: Colorectal cancer | diagnostic | Read |
| B804 | Carcinoma in situ of rectum and rectosigmoid junction | res17: Colorectal cancer | diagnostic | Read |
| B8040 | Carcinoma in situ of rectosigmoid junction | res17: Colorectal cancer | diagnostic | Read |
| B8041 | Carcinoma in situ of rectum | res17: Colorectal cancer | diagnostic | Read |
| B804z | Carcinoma in situ of rectum or rectosigmoid junction NOS | res17: Colorectal cancer | diagnostic | Read |
| B902 | Neop of uncertain behaviour stomach, intestines and rectum | res17: Colorectal cancer | diagnostic | Read |
| B9024 | Neoplasm of uncertain behaviour of colon | res17: Colorectal cancer | diagnostic | Read |
| B9025 | Neoplasm of uncertain behaviour of rectum | res17: Colorectal cancer | diagnostic | Read |
| B902z | Neop of uncertain behaviour stomach, intestine or rectum NOS | res17: Colorectal cancer | diagnostic | Read |
| BB5N | [M]Adenomatous and adenocarcinomatous polyps of colon | res17: Colorectal cancer | diagnostic | Read |
| EGTON2B152 | Cause of Death- Ca Rectum | res17: Colorectal cancer | diagnostic | Read |
| EMISNQHE41 | Hereditary nonpolyposis colon cancer | res17: Colorectal cancer | diagnostic | Read |
| HNG0201 | [RFC] Cancer of the rectum | res17: Colorectal cancer | diagnostic | Read |
To Export Phenotype Details:
| Format | API |
|---|---|
| XML | site_root/api/v1/public/phenotypes/PH453/version/906/detail/?format=xml |
| JSON | site_root/api/v1/public/phenotypes/PH453/version/906/detail/?format=json |
| R Package |
|
To Export Phenotype Code List:
| Format | API |
|---|---|
| XML | site_root/api/v1/public/phenotypes/PH453/version/906/export/codes/?format=xml |
| JSON | site_root/api/v1/public/phenotypes/PH453/version/906/export/codes/?format=json |
| CSV | site_root/phenotypes/PH453/version/906/export/codes/ |
| R Package |
|
| Version ID |
Name | Owner | Publish date | |
|---|---|---|---|---|
| 906 | Colorectal Cancer | ieuan.scanlon | 2021-10-06 | currently shown |
Export - export all codes into a csv file/JSON/XML for the current phenotype version.
Print - Print page.