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Ehnicity

Caroline Fairhust, Fabiola Martin, Ian Watt, Tim Doran, Martin Bland, William J Brackenbury

Type
Lifestyle Risk Factor
ID
PH456
Version ID
912
Data Sources
Valid event data range
start - 31/12/2014
Sex
Female, Male
Agreement Date
2016-09-06
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Introduction:

Voltage-gated sodium channel (VGSC)- inhibiting drugs are commonly used to treat epilepsy and cardiac arrhythmia. VGSCs are also widely expressed in various cancers, including those of the breast, bowel and prostate. A number of VGSCinhibiting drugs have been shown to inhibit cancer cell proliferation, invasion, tumour growth and metastasis in preclinical models, suggesting that VGSCs may be novel molecular targets for cancer treatment. Surprisingly, we previously found that prior exposure to VGSC-inhibiting drugs may be associated with reduced overall survival in patients with cancer, but we were unable to control for the cause of death or indication for prescription. The purpose of the present study is to interrogate a different database to further investigate the relationship between VGSC-inhibiting drugs and cancer-specific survival.

Methods and analysis:

A cohort study using primary care data from the Clinical Practice Research Datalink database will include patients with diagnosis of breast, bowel and prostate cancer (13 000). The primary outcome will be cancer-specific survival from the date of cancer diagnosis. Cox proportional hazards regression will be used to compare survival of patients taking VGSC-inhibiting drugs (including antiepileptic drugs and class I antiarrhythmic agents) with patients with cancer not taking these drugs, adjusting for cancer type, age and sex. Drug exposure will be treated as a time-varying covariate to account for potential immortal time bias. Various sensitivity and secondary analyses will be performed.

Publications

  • Caroline Fairhust, Fabiola Martin, Ian Watt, Tim Doran, Martin Bland, William J Brackenbury, Sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the CPRD primary care database. BMJ Open, 6(e0111661), 2016.

Clinical Code List

Rows: 168
Code Description Entity type Category Coding System (Read)
916E.00 Patient ethnicity unknown res47: Ethnicity test Read
918t.00 Carer from Black and minority ethnic group res47: Ethnicity test Read
9S...00 Ethnic groups (census) res47: Ethnicity test Read
9S1..00 White res47: Ethnicity test Read
9S10.00 White British res47: Ethnicity test Read
9S11.00 White Irish res47: Ethnicity test Read
9S12.00 Other white ethnic group res47: Ethnicity test Read
9S13.00 White Scottish res47: Ethnicity test Read
9S14.00 Other white British ethnic group res47: Ethnicity test Read
9S2..00 Black Caribbean res47: Ethnicity test Read
9S3..00 Black African res47: Ethnicity test Read
9S4..00 Black, other, non-mixed origin res47: Ethnicity test Read
9S41.00 Black British res47: Ethnicity test Read
9S42.00 Black Caribbean/W.I./Guyana res47: Ethnicity test Read
9S42.11 Black Caribbean res47: Ethnicity test Read
9S42.12 Black West Indian res47: Ethnicity test Read
9S42.13 Black Guyana res47: Ethnicity test Read
9S43.00 Black N African/Arab/Iranian res47: Ethnicity test Read
9S43.11 Black North African res47: Ethnicity test Read
9S43.12 Black Arab res47: Ethnicity test Read
9S43.13 Black Iranian res47: Ethnicity test Read
9S44.00 Black - other African country res47: Ethnicity test Read
9S45.00 Black E Afric Asia/Indo-Caribb res47: Ethnicity test Read
9S45.11 Black East African Asian res47: Ethnicity test Read
9S45.12 Black Indo-Caribbean res47: Ethnicity test Read
9S46.00 Black Indian sub-continent res47: Ethnicity test Read
9S47.00 Black - other Asian res47: Ethnicity test Read
9S48.00 Black Black - other res47: Ethnicity test Read
9S5..00 Black - other, mixed res47: Ethnicity test Read
9S51.00 Other Black - Black/White orig res47: Ethnicity test Read
9S52.00 Other Black - Black/Asian orig res47: Ethnicity test Read
9S6..00 Indian res47: Ethnicity test Read
9S7..00 Pakistani res47: Ethnicity test Read
9S8..00 Bangladeshi res47: Ethnicity test Read
9S9..00 Chinese res47: Ethnicity test Read
9SA..00 Other ethnic non-mixed (NMO) res47: Ethnicity test Read
9SA1.00 Brit. ethnic minor. spec.(NMO) res47: Ethnicity test Read
9SA2.00 Brit. ethnic minor. unsp (NMO) res47: Ethnicity test Read
9SA3.00 Caribbean I./W.I./Guyana (NMO) res47: Ethnicity test Read
9SA3.11 Caribbean Island (NMO) res47: Ethnicity test Read
9SA3.12 West Indian (NMO) res47: Ethnicity test Read
9SA3.13 Guyana (NMO) res47: Ethnicity test Read
9SA4.00 N African Arab/Iranian (NMO) res47: Ethnicity test Read
9SA4.11 North African Arab (NMO) res47: Ethnicity test Read
9SA4.12 Iranian (NMO) res47: Ethnicity test Read
9SA5.00 Other African countries (NMO) res47: Ethnicity test Read
9SA6.00 E Afric Asian/Indo-Carib (NMO) res47: Ethnicity test Read
9SA6.11 East African Asian (NMO) res47: Ethnicity test Read
9SA6.12 Indo-Caribbean (NMO) res47: Ethnicity test Read
9SA7.00 Indian sub-continent (NMO) res47: Ethnicity test Read
9SA8.00 Other Asian (NMO) res47: Ethnicity test Read
9SA9.00 Irish (NMO) res47: Ethnicity test Read
9SAA.00 Greek/Greek Cypriot (NMO) res47: Ethnicity test Read
9SAA.11 Greek (NMO) res47: Ethnicity test Read
9SAA.12 Greek Cypriot (NMO) res47: Ethnicity test Read
9SAB.00 Turkish/Turkish Cypriot (NMO) res47: Ethnicity test Read
9SAB.11 Turkish (NMO) res47: Ethnicity test Read
9SAB.12 Turkish Cypriot (NMO) res47: Ethnicity test Read
9SAC.00 Other European (NMO) res47: Ethnicity test Read
9SAD.00 Other ethnic NEC (NMO) res47: Ethnicity test Read
9SB..00 Other ethnic, mixed origin res47: Ethnicity test Read
9SB1.00 Other ethnic, Black/White orig res47: Ethnicity test Read
9SB2.00 Other ethnic, Asian/White orig res47: Ethnicity test Read
9SB3.00 Other ethnic, mixed white orig res47: Ethnicity test Read
9SB4.00 Other ethnic, other mixed orig res47: Ethnicity test Read
9SB5.00 Black Caribbean and White res47: Ethnicity test Read
9SB6.00 Black African and White res47: Ethnicity test Read
9SC..00 Vietnamese res47: Ethnicity test Read
9SD..00 Ethnic group not given - patient refused res47: Ethnicity test Read
9SE..00 Ethnic group not recorded res47: Ethnicity test Read
9SG..00 Other black ethnic group res47: Ethnicity test Read
9SH..00 Other Asian ethnic group res47: Ethnicity test Read
9SI..00 Irish traveller res47: Ethnicity test Read
9SJ..00 Other ethnic group res47: Ethnicity test Read
9SZ..00 Ethnic groups (census) NOS res47: Ethnicity test Read
9T15.00 Cook Island Maori res47: Ethnicity test Read
9T1C.00 Chinese res47: Ethnicity test Read
9T5..00 Bulgarian res47: Ethnicity test Read
9T6..00 Czech res47: Ethnicity test Read
9i...00 Ethnic category - 2001 census res47: Ethnicity test Read
9i0..00 British or mixed British - ethnic category 2001 census res47: Ethnicity test Read
9i00.00 White British - ethnic category 2001 census res47: Ethnicity test Read
9i1..00 Irish - ethnic category 2001 census res47: Ethnicity test Read
9i10.00 White Irish - ethnic category 2001 census res47: Ethnicity test Read
9i2..00 Other White background - ethnic category 2001 census res47: Ethnicity test Read
9i20.00 English - ethnic category 2001 census res47: Ethnicity test Read
9i21.00 Scottish - ethnic category 2001 census res47: Ethnicity test Read
9i22.00 Welsh - ethnic category 2001 census res47: Ethnicity test Read
9i23.00 Cornish - ethnic category 2001 census res47: Ethnicity test Read
9i24.00 Northern Irish - ethnic category 2001 census res47: Ethnicity test Read
9i25.00 Ulster Scots - ethnic category 2001 census res47: Ethnicity test Read
9i26.00 Cypriot (part not stated) - ethnic category 2001 census res47: Ethnicity test Read
9i27.00 Greek - ethnic category 2001 census res47: Ethnicity test Read
9i28.00 Greek Cypriot - ethnic category 2001 census res47: Ethnicity test Read
9i29.00 Turkish - ethnic category 2001 census res47: Ethnicity test Read
9i2A.00 Turkish Cypriot - ethnic category 2001 census res47: Ethnicity test Read
9i2B.00 Italian - ethnic category 2001 census res47: Ethnicity test Read
9i2C.00 Irish Traveller - ethnic category 2001 census res47: Ethnicity test Read
9i2D.00 Traveller - ethnic category 2001 census res47: Ethnicity test Read
9i2E.00 Gypsy/Romany - ethnic category 2001 census res47: Ethnicity test Read
9i2F.00 Polish - ethnic category 2001 census res47: Ethnicity test Read
9i2G.00 Baltic Estonian/Latvian/Lithuanian - ethn categ 2001 census res47: Ethnicity test Read
9i2H.00 Commonwealth (Russian) Indep States - ethn categ 2001 census res47: Ethnicity test Read
9i2J.00 Kosovan - ethnic category 2001 census res47: Ethnicity test Read
9i2K.00 Albanian - ethnic category 2001 census res47: Ethnicity test Read
9i2L.00 Bosnian - ethnic category 2001 census res47: Ethnicity test Read
9i2M.00 Croatian - ethnic category 2001 census res47: Ethnicity test Read
9i2N.00 Serbian - ethnic category 2001 census res47: Ethnicity test Read
9i2P.00 Other republics former Yugoslavia - ethnic categ 2001 census res47: Ethnicity test Read
9i2Q.00 Mixed Irish and other White - ethnic category 2001 census res47: Ethnicity test Read
9i2R.00 Oth White European/European unsp/Mixed European 2001 census res47: Ethnicity test Read
9i2S.00 Other mixed White - ethnic category 2001 census res47: Ethnicity test Read
9i2T.00 Other White or White unspecified ethnic category 2001 census res47: Ethnicity test Read
9i3..00 White and Black Caribbean - ethnic category 2001 census res47: Ethnicity test Read
9i4..00 White and Black African - ethnic category 2001 census res47: Ethnicity test Read
9i5..00 White and Asian - ethnic category 2001 census res47: Ethnicity test Read
9i6..00 Other Mixed background - ethnic category 2001 census res47: Ethnicity test Read
9i60.00 Black and Asian - ethnic category 2001 census res47: Ethnicity test Read
9i61.00 Black and Chinese - ethnic category 2001 census res47: Ethnicity test Read
9i62.00 Black and White - ethnic category 2001 census res47: Ethnicity test Read
9i63.00 Chinese and White - ethnic category 2001 census res47: Ethnicity test Read
9i64.00 Asian and Chinese - ethnic category 2001 census res47: Ethnicity test Read
9i65.00 Other Mixed or Mixed unspecified ethnic category 2001 census res47: Ethnicity test Read
9i7..00 Indian or British Indian - ethnic category 2001 census res47: Ethnicity test Read
9i8..00 Pakistani or British Pakistani - ethnic category 2001 census res47: Ethnicity test Read
9i9..00 Bangladeshi or British Bangladeshi - ethn categ 2001 census res47: Ethnicity test Read
9iA..00 Other Asian background - ethnic category 2001 census res47: Ethnicity test Read
9iA1.00 Punjabi - ethnic category 2001 census res47: Ethnicity test Read
9iA2.00 Kashmiri - ethnic category 2001 census res47: Ethnicity test Read
9iA3.00 East African Asian - ethnic category 2001 census res47: Ethnicity test Read
9iA4.00 Sri Lankan - ethnic category 2001 census res47: Ethnicity test Read
9iA5.00 Tamil - ethnic category 2001 census res47: Ethnicity test Read
9iA6.00 Sinhalese - ethnic category 2001 census res47: Ethnicity test Read
9iA7.00 Caribbean Asian - ethnic category 2001 census res47: Ethnicity test Read
9iA8.00 British Asian - ethnic category 2001 census res47: Ethnicity test Read
9iA9.00 Mixed Asian - ethnic category 2001 census res47: Ethnicity test Read
9iAA.00 Other Asian or Asian unspecified ethnic category 2001 census res47: Ethnicity test Read
9iB..00 Caribbean - ethnic category 2001 census res47: Ethnicity test Read
9iC..00 African - ethnic category 2001 census res47: Ethnicity test Read
9iD..00 Other Black background - ethnic category 2001 census res47: Ethnicity test Read
9iD0.00 Somali - ethnic category 2001 census res47: Ethnicity test Read
9iD1.00 Nigerian - ethnic category 2001 census res47: Ethnicity test Read
9iD2.00 Black British - ethnic category 2001 census res47: Ethnicity test Read
9iD3.00 Mixed Black - ethnic category 2001 census res47: Ethnicity test Read
9iD4.00 Other Black or Black unspecified ethnic category 2001 census res47: Ethnicity test Read
9iE..00 Chinese - ethnic category 2001 census res47: Ethnicity test Read
9iF..00 Other - ethnic category 2001 census res47: Ethnicity test Read
9iF0.00 Vietnamese - ethnic category 2001 census res47: Ethnicity test Read
9iF1.00 Japanese - ethnic category 2001 census res47: Ethnicity test Read
9iF2.00 Filipino - ethnic category 2001 census res47: Ethnicity test Read
9iF3.00 Malaysian - ethnic category 2001 census res47: Ethnicity test Read
9iF4.00 Buddhist - ethnic category 2001 census res47: Ethnicity test Read
9iF5.00 Hindu - ethnic category 2001 census res47: Ethnicity test Read
9iF6.00 Jewish - ethnic category 2001 census res47: Ethnicity test Read
9iF7.00 Muslim - ethnic category 2001 census res47: Ethnicity test Read
9iF8.00 Sikh - ethnic category 2001 census res47: Ethnicity test Read
9iF9.00 Arab - ethnic category 2001 census res47: Ethnicity test Read
9iFA.00 North African - ethnic category 2001 census res47: Ethnicity test Read
9iFB.00 Mid East (excl Israeli, Iranian & Arab) - eth cat 2001 cens res47: Ethnicity test Read
9iFC.00 Israeli - ethnic category 2001 census res47: Ethnicity test Read
9iFD.00 Iranian - ethnic category 2001 census res47: Ethnicity test Read
9iFE.00 Kurdish - ethnic category 2001 census res47: Ethnicity test Read
9iFF.00 Moroccan - ethnic category 2001 census res47: Ethnicity test Read
9iFG.00 Latin American - ethnic category 2001 census res47: Ethnicity test Read
9iFH.00 South and Central American - ethnic category 2001 census res47: Ethnicity test Read
9iFJ.00 Mauritian/Seychellois/Maldivian/St Helena eth cat 2001census res47: Ethnicity test Read
9iFK.00 Any other group - ethnic category 2001 census res47: Ethnicity test Read
9iG..00 Ethnic category not stated - 2001 census res47: Ethnicity test Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH456/version/912/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH456/version/912/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH456', '912', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH456/version/912/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH456/version/912/export/codes/?format=json
CSV site_root/phenotypes/PH456/version/912/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH456', '912', api_client=client)

Version History

Version
ID
Name Owner Publish date
912 Ehnicity ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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