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Metastases

Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenbury

Type
Disease or Syndrome
ID
PH458
Version ID
916
Data Sources
Valid event data range
01/01/1998 - 31/12/2013
Sex
Female, Male
Agreement Date
2014-11-14
Coding system
Read codes v2
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

A cohort study based on primary care data from the QResearch database will include patients with one of the three common tumours: breast, bowel and prostate. The primary outcome will be overall survival from the date of cancer diagnosis. Cox proportional hazards regression will be used to compare the survival of patients with cancer taking VGSC-inhibiting drugs (including anticonvulsants and class I antiarrhythmic agents) with patients with cancer not exposed to these drugs, adjusting for age and sex. Exposure to VGSC-inhibiting drugs will be defined as having at least one prescription for these drugs prior to cancer diagnosis. High and low exposure groups will be identified based on the length of use. A number of sensitivity and secondary analyses will be conducted.

Publications

  • Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenburry, Exposure to sodium channel-inhibiting drugs and cancer survival protocol for a cohort study using the QResearch primary care database. BMJ Open, 4:e006604 2014.

Clinical Code List

Rows: 117
Code Description Entity type Category Coding System (Read)
1D18 Pain from metastases res17: Metastases symptom Read
B153 Secondary malignant neoplasm of liver res17: Metastases symptom Read
B56 Secondary and unspecified malignant neoplasm of lymph nodes res17: Metastases symptom Read
B56-1 Lymph node metastases res17: Metastases symptom Read
B560 Secondary and unspec malig neop lymph nodes head/face/neck res17: Metastases symptom Read
B560-99 Secondary nodes - head/neck res17: Metastases symptom Read
B5600 Secondary and unspec malig neop of superficial parotid LN res17: Metastases symptom Read
B5601 Secondary and unspec malignant neoplasm mastoid lymph nodes res17: Metastases symptom Read
B5602 Secondary and unspec malig neop superficial cervical LN res17: Metastases symptom Read
B5603 Secondary and unspec malignant neoplasm occipital lymph node res17: Metastases symptom Read
B5604 Secondary and unspec malig neop deep parotid lymph nodes res17: Metastases symptom Read
B5605 Secondary and unspec malig neop submandibular lymph nodes res17: Metastases symptom Read
B5606 Secondary and unspec malig neop of facial lymph nodes res17: Metastases symptom Read
B5607 Secondary and unspec malig neop submental lymph nodes res17: Metastases symptom Read
B5608 Secondary and unspec malig neop anterior cervical LN res17: Metastases symptom Read
B5609 Secondary and unspec malig neop deep cervical LN res17: Metastases symptom Read
B560z Secondary unspec malig neop lymph nodes head/face/neck NOS res17: Metastases symptom Read
B561 Secondary and unspec malig neop intrathoracic lymph nodes res17: Metastases symptom Read
B561-99 Secondary nodes -intrathoracic res17: Metastases symptom Read
B5610 Secondary and unspec malig neop internal mammary lymph nodes res17: Metastases symptom Read
B5611 Secondary and unspec malig neop intercostal lymph nodes res17: Metastases symptom Read
B5612 Secondary and unspec malig neop diaphragmatic lymph nodes res17: Metastases symptom Read
B5613 Secondary and unspec malig neop ant mediastinal lymph nodes res17: Metastases symptom Read
B5614 Secondary and unspec malig neop post mediastinal lymph nodes res17: Metastases symptom Read
B5615 Secondary and unspec malig neop paratracheal lymph nodes res17: Metastases symptom Read
B5616 Secondary and unspec malig neop superfic tracheobronchial LN res17: Metastases symptom Read
B5617 Secondary and unspec malig neop inferior tracheobronchial LN res17: Metastases symptom Read
B5618 Secondary and unspec malig neop bronchopulmonary lymph nodes res17: Metastases symptom Read
B5619 Secondary and unspec malig neop pulmonary lymph nodes res17: Metastases symptom Read
B561z Secondary and unspec malig neop intrathoracic LN NOS res17: Metastases symptom Read
B562 Secondary and unspec malig neop intra-abdominal lymph nodes res17: Metastases symptom Read
B562-99 Secondary nodes - intra.abdom. res17: Metastases symptom Read
B5620 Secondary and unspec malig neop coeliac lymph nodes res17: Metastases symptom Read
B5621 Secondary and unspec malig neop superficial mesenteric LN res17: Metastases symptom Read
B5622 Secondary and unspec malig neop inferior mesenteric LN res17: Metastases symptom Read
B5623 Secondary and unspec malig neop common iliac lymph nodes res17: Metastases symptom Read
B5624 Secondary and unspec malig neop external iliac lymph nodes res17: Metastases symptom Read
B562z Secondary and unspec malig neop intra-abdominal LN NOS res17: Metastases symptom Read
B563 Secondary and unspec malig neop axilla and upper limb LN res17: Metastases symptom Read
B563-99 Secondary nodes - axilla/arm res17: Metastases symptom Read
B5630 Secondary and unspec malig neop axillary lymph nodes res17: Metastases symptom Read
B5631 Secondary and unspec malig neop supratrochlear lymph nodes res17: Metastases symptom Read
B5632 Secondary and unspec malig neop infraclavicular lymph nodes res17: Metastases symptom Read
B5633 Secondary and unspec malig neop pectoral lymph nodes res17: Metastases symptom Read
B563z Secondary and unspec malig neop axilla and upper limb LN NOS res17: Metastases symptom Read
B564 Secondary and unspec malig neop inguinal and lower limb LN res17: Metastases symptom Read
B564-99 Secondary nodes - inguinal/leg res17: Metastases symptom Read
B5640 Secondary and unspec malig neop superficial inguinal LN res17: Metastases symptom Read
B5641 Secondary and unspec malig neop deep inguinal lymph nodes res17: Metastases symptom Read
B5642 Secondary and unspec malig neop popliteal lymph nodes res17: Metastases symptom Read
B564z Secondary and unspec malig neop of inguinal and leg LN NOS res17: Metastases symptom Read
B565 Secondary and unspec malig neop intrapelvic lymph nodes res17: Metastases symptom Read
B565-99 Secondary nodes - intrapelvic res17: Metastases symptom Read
B5650 Secondary and unspec malig neop internal iliac lymph nodes res17: Metastases symptom Read
B5651 Secondary and unspec malig neop inferior epigastric LN res17: Metastases symptom Read
B5652 Secondary and unspec malig neop circumflex iliac LN res17: Metastases symptom Read
B5653 Secondary and unspec malig neop sacral lymph nodes res17: Metastases symptom Read
B5654 Secondary and unspec malig neop obturator lymph nodes res17: Metastases symptom Read
B565z Secondary and unspec malig neop intrapelvic LN NOS res17: Metastases symptom Read
B56y Secondary and unspec malig neop lymph nodes multiple sites res17: Metastases symptom Read
B56y-99 Secondary nodes - multiple res17: Metastases symptom Read
B56z Secondary and unspec malig neop lymph nodes NOS res17: Metastases symptom Read
B56z-99 Secondary nodes NOS res17: Metastases symptom Read
B57-1 Metastases of respiratory and/or digestive systems res17: Metastases symptom Read
B570 Secondary malignant neoplasm of lung res17: Metastases symptom Read
B571 Secondary malignant neoplasm of mediastinum res17: Metastases symptom Read
B572 Secondary malignant neoplasm of pleura res17: Metastases symptom Read
B573 Secondary malignant neoplasm of other respiratory organs res17: Metastases symptom Read
B574 Secondary malignant neoplasm of small intestine and duodenum res17: Metastases symptom Read
B5740 Secondary malignant neoplasm of duodenum res17: Metastases symptom Read
B5741 Secondary malignant neoplasm of jejunum res17: Metastases symptom Read
B5742 Secondary malignant neoplasm of ileum res17: Metastases symptom Read
B574z Secondary malig neop of small intestine or duodenum NOS res17: Metastases symptom Read
B575 Secondary malignant neoplasm of large intestine and rectum res17: Metastases symptom Read
B5750 Secondary malignant neoplasm of colon res17: Metastases symptom Read
B5751 Secondary malignant neoplasm of rectum res17: Metastases symptom Read
B575z Secondary malig neop of large intestine or rectum NOS res17: Metastases symptom Read
B5760 Secondary malignant neoplasm of retroperitoneum res17: Metastases symptom Read
B5761 Secondary malignant neoplasm of peritoneum res17: Metastases symptom Read
B577 Secondary malignant neoplasm of liver res17: Metastases symptom Read
B577-1 Liver metastases res17: Metastases symptom Read
B57y Secondary malignant neoplasm of other digestive organ res17: Metastases symptom Read
B58 Secondary malignant neoplasm of other specified sites res17: Metastases symptom Read
B580 Secondary malignant neoplasm of kidney res17: Metastases symptom Read
B5823 Secondary malignant neoplasm of skin of trunk res17: Metastases symptom Read
B5826 Secondary malignant neoplasm of skin of breast res17: Metastases symptom Read
B583 Secondary malignant neoplasm of brain and spinal cord res17: Metastases symptom Read
B583-99 Secondary Ca brain/spinal cord res17: Metastases symptom Read
B5830 Secondary malignant neoplasm of brain res17: Metastases symptom Read
B5831 Secondary malignant neoplasm of spinal cord res17: Metastases symptom Read
B5832 Cerebral metastasis res17: Metastases symptom Read
B583z Secondary malignant neoplasm of brain or spinal cord NOS res17: Metastases symptom Read
B584 Secondary malignant neoplasm of other part of nervous system res17: Metastases symptom Read
B585 Secondary malignant neoplasm of bone and bone marrow res17: Metastases symptom Read
B585-99 Secondary Ca bone/bone marrow res17: Metastases symptom Read
B5850 Pathological fracture due to metastatic bone disease res17: Metastases symptom Read
B586 Secondary malignant neoplasm of ovary res17: Metastases symptom Read
B587 Secondary malignant neoplasm of adrenal gland res17: Metastases symptom Read
B58y Secondary malignant neoplasm of other specified sites res17: Metastases symptom Read
B58y0 Secondary malignant neoplasm of breast res17: Metastases symptom Read
B58y5 Secondary malignant neoplasm of prostate res17: Metastases symptom Read
B58yz Secondary malignant neoplasm of other specified site NOS res17: Metastases symptom Read
B58z Secondary malignant neoplasm of other specified site NOS res17: Metastases symptom Read
B58z-99 Secondary Ca NOS res17: Metastases symptom Read
B594 Secondary malignant neoplasm of unknown site res17: Metastases symptom Read
ByuC [X]Malignant neoplasm of ill-defined, secondary and unspeci res17: Metastases symptom Read
ByuC3 [X]Secondary malignant neoplasm/oth+unspc respiratory organs res17: Metastases symptom Read
ByuC4 [X]Secondary malignant neoplasm/oth+unspcfd digestive organs res17: Metastases symptom Read
ByuC7 [X]Secondary malignant neoplasm of other specified sites res17: Metastases symptom Read
EMISNQME41 Metastasis stage M0 res17: Metastases symptom Read
EMISNQME42 Metastasis stage M1 res17: Metastases symptom Read
EMISNQME43 Metastasis stage M2 res17: Metastases symptom Read
EMISNQME44 Metastasis stage M3 res17: Metastases symptom Read
EMISNQME45 Metastasis stage M4 res17: Metastases symptom Read
EMISNQME46 Metastasis stage M1a res17: Metastases symptom Read
EMISNQME47 Metastasis stage M1b res17: Metastases symptom Read
EMISNQME48 Metastasis stage M1c res17: Metastases symptom Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH458/version/916/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH458/version/916/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH458', '916', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH458/version/916/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH458/version/916/export/codes/?format=json
CSV site_root/phenotypes/PH458/version/916/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH458', '916', api_client=client)

Version History

Version
ID
Name Owner Publish date
916 Metastases ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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