A cohort study based on primary care data from the QResearch database will include patients with one of the three common tumours: breast, bowel and prostate. The primary outcome will be overall survival from the date of cancer diagnosis. Cox proportional hazards regression will be used to compare the survival of patients with cancer taking VGSC-inhibiting drugs (including anticonvulsants and class I antiarrhythmic agents) with patients with cancer not exposed to these drugs, adjusting for age and sex. Exposure to VGSC-inhibiting drugs will be defined as having at least one prescription for these drugs prior to cancer diagnosis. High and low exposure groups will be identified based on the length of use. A number of sensitivity and secondary analyses will be conducted.
Caroline Fairhurst, Ian Watt, Fabiola Martin, Martin Bland, William J Brackenburry, Exposure to sodium channel-inhibiting drugs and cancer survival protocol for a cohort study using the QResearch primary care database. BMJ Open, 4:e006604 2014.
Code | Description | Entity type | Category | Coding System (Read) |
---|---|---|---|---|
137-1 | Smoker - amount smoked | res17: Smoking status | test | Read |
1371 | Never smoked tobacco | res17: Smoking status | test | Read |
1371-1 | Non-smoker | res17: Smoking status | test | Read |
1372 | Trivial smoker - < 1 cig/day | res17: Smoking status | test | Read |
1372-1 | Occasional smoker | res17: Smoking status | test | Read |
1373 | Light smoker - 1-9 cigs/day | res17: Smoking status | test | Read |
1374 | Moderate smoker - 10-19 cigs/d | res17: Smoking status | test | Read |
1375 | Heavy smoker - 20-39 cigs/day | res17: Smoking status | test | Read |
1376 | Very heavy smoker - 40+cigs/d | res17: Smoking status | test | Read |
1377 | Ex-trivial smoker (<1/day) | res17: Smoking status | test | Read |
1378 | Ex-light smoker (1-9/day) | res17: Smoking status | test | Read |
1379 | Ex-moderate smoker (10-19/day) | res17: Smoking status | test | Read |
137A | Ex-heavy smoker (20-39/day) | res17: Smoking status | test | Read |
137B | Ex-very heavy smoker (40+/day) | res17: Smoking status | test | Read |
137C | Keeps trying to stop smoking | res17: Smoking status | test | Read |
137D | Admitted tobacco cons untrue ? | res17: Smoking status | test | Read |
137E | Tobacco consumption unknown | res17: Smoking status | test | Read |
137F | Ex-smoker - amount unknown | res17: Smoking status | test | Read |
137F-99 | EX-Smoker NOS | res17: Smoking status | test | Read |
137G | Trying to give up smoking | res17: Smoking status | test | Read |
137H | Pipe smoker | res17: Smoking status | test | Read |
137I | Passive smoker | res17: Smoking status | test | Read |
137I0 | Exposed to tobacco smoke at home | res17: Smoking status | test | Read |
137J | Cigar smoker | res17: Smoking status | test | Read |
137K | Stopped smoking | res17: Smoking status | test | Read |
137K0 | Recently stopped smoking | res17: Smoking status | test | Read |
137L | Current non-smoker | res17: Smoking status | test | Read |
137L-99 | Tobacco Consumption Nil | res17: Smoking status | test | Read |
137M | Rolls own cigarettes | res17: Smoking status | test | Read |
137N | Ex pipe smoker | res17: Smoking status | test | Read |
137O | Ex cigar smoker | res17: Smoking status | test | Read |
137P | Cigarette smoker | res17: Smoking status | test | Read |
137P-1 | Smoker | res17: Smoking status | test | Read |
137Q | Smoking started | res17: Smoking status | test | Read |
137Q-1 | Smoking restarted | res17: Smoking status | test | Read |
137R | Current smoker | res17: Smoking status | test | Read |
137S | Ex smoker | res17: Smoking status | test | Read |
137T | Date ceased smoking | res17: Smoking status | test | Read |
137U | Not a passive smoker | res17: Smoking status | test | Read |
137V | Smoking reduced | res17: Smoking status | test | Read |
137W | Chews tobacco | res17: Smoking status | test | Read |
137X | Cigarette consumption | res17: Smoking status | test | Read |
137Y | Cigar consumption | res17: Smoking status | test | Read |
137Z | Tobacco consumption NOS | res17: Smoking status | test | Read |
137a | Pipe tobacco consumption | res17: Smoking status | test | Read |
137b | Ready to stop smoking | res17: Smoking status | test | Read |
137c | Thinking about stopping smoking | res17: Smoking status | test | Read |
137d | Not interested in stopping smoking | res17: Smoking status | test | Read |
137e | Smoking restarted | res17: Smoking status | test | Read |
137f | Reason for restarting smoking | res17: Smoking status | test | Read |
137g | Cigarette pack-years | res17: Smoking status | test | Read |
137h | Minutes from waking to first tobacco consumption | res17: Smoking status | test | Read |
137i | Ex-tobacco chewer | res17: Smoking status | test | Read |
137j | Ex-cigarette smoker | res17: Smoking status | test | Read |
137k | Refusal to give smoking status | res17: Smoking status | test | Read |
137l | Ex roll-up cigarette smoker | res17: Smoking status | test | Read |
137m | Failed attempt to stop smoking | res17: Smoking status | test | Read |
137n | Total time smoked | res17: Smoking status | test | Read |
137o | Waterpipe tobacco consumption | res17: Smoking status | test | Read |
13WF-1 | Smoker in the family | res17: Smoking status | test | Read |
13p | Smoking cessation milestones | res17: Smoking status | test | Read |
13p0 | Negotiated date for cessation of smoking | res17: Smoking status | test | Read |
13p1 | Smoking status at 4 weeks | res17: Smoking status | test | Read |
13p2 | Smoking status between 4 and 52 weeks | res17: Smoking status | test | Read |
13p3 | Smoking status at 52 weeks | res17: Smoking status | test | Read |
13p4 | Smoking free weeks | res17: Smoking status | test | Read |
13p7 | Smoking status at 12 weeks | res17: Smoking status | test | Read |
9ko | Current smoker annual review - enhanced services admin | res17: Smoking status | test | Read |
9ko-1 | Current smoker annual review | res17: Smoking status | test | Read |
ASDFGNO1 | Non Smoker - Nos | res17: Smoking status | test | Read |
EGTON1024 | Rolls own cigarettes | res17: Smoking status | test | Read |
EGTON1025 | Current Smoker NOS | res17: Smoking status | test | Read |
EGTON1026 | Ex-cigar smoker | res17: Smoking status | test | Read |
EGTON1027 | Ex- Rolled Tobacco Smoker | res17: Smoking status | test | Read |
EGTON1028 | Ex-smoker NOS | res17: Smoking status | test | Read |
EGTON320 | Smoking Status | res17: Smoking status | test | Read |
EGTON321 | Cigarette smoker | res17: Smoking status | test | Read |
EGTON322 | Ex-Cigarette Smoker | res17: Smoking status | test | Read |
EGTON324 | Ex-pipe smoker | res17: Smoking status | test | Read |
EGTON326 | Current smoker | res17: Smoking status | test | Read |
EGTON327 | Past smoker | res17: Smoking status | test | Read |
EGTON328 | Date stopped smoking | res17: Smoking status | test | Read |
EGTONGR11 | Grade B light smoker (1-10/day) | res17: Smoking status | test | Read |
EGTONGR12 | Grade C moderate smoker (11-20/day) | res17: Smoking status | test | Read |
EGTONGR13 | Grade D heavy smoker (>20 Day) | res17: Smoking status | test | Read |
EGTONSM2 | Smoking Age | res17: Smoking status | test | Read |
EGTONSM3 | Smoking Age Started | res17: Smoking status | test | Read |
EGTONSM4 | Smoking Age Ceased | res17: Smoking status | test | Read |
EGTONSM6 | Smoking clinic | res17: Smoking status | test | Read |
EMISNQEX4 | Ex-tobacco chewer | res17: Smoking status | test | Read |
EMISNQPR396 | Primary carer current smoker | res17: Smoking status | test | Read |
EMISNQSM14 | Smoking increased | res17: Smoking status | test | Read |
EMISNQSN1 | Snuff use | res17: Smoking status | test | Read |
EMISNQTO12 | Total time smoked | res17: Smoking status | test | Read |
EMISNQWA11 | Waterpipe tobacco consumption | res17: Smoking status | test | Read |
EMISOTS1 | Other smoking information | res17: Smoking status | test | Read |
EMISQCO3 | Carbon monoxide validation confirms smoker | res17: Smoking status | test | Read |
EMISQDA1 | Date of last cigarette | res17: Smoking status | test | Read |
EMISQGR1 | Gradual smoking reduction | res17: Smoking status | test | Read |
EMISSMRE1 | Smoker (Read codes) | res17: Smoking status | test | Read |
PCSDT1DE9 | Dependent smoker | res17: Smoking status | test | Read |
PCSDT1HE1 | Heavy smoker review due | res17: Smoking status | test | Read |
To Export Phenotype Details:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH461/version/922/detail/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH461/version/922/detail/?format=json |
R Package |
|
To Export Phenotype Code List:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH461/version/922/export/codes/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH461/version/922/export/codes/?format=json |
CSV | site_root/phenotypes/PH461/version/922/export/codes/ |
R Package |
|
Version ID |
Name | Owner | Publish date | |
---|---|---|---|---|
922 | Smoking Status | ieuan.scanlon | 2021-10-06 | currently shown |
Export - export all codes into a csv file/JSON/XML for the current phenotype version.
Print - Print page.