Data source:
We used the Clinical Practice Research Datalink (CPRD), a large primary care database that holds complete electronic patient records (including diagnoses, prescriptions and referrals) from participating family practices across the UK. A hierarchical clinical coding system (Read) is used to record the data. In July 2012, data were available for 644 practices and 13,772,992 patients. Full details of the database have been provided elsewhere.
Diabetes cohort:
We extracted data from 1 April 2006 to 31 March 2012 and, for ease of reporting and analysing, aggregated information into six financial years. Within each year, practice inclusion eligibility was determined by a CPRD assessment algorithm, which informs on practices considered to be of research standard; therefore, our cohort of practices varied over time. For each research standard practice and year, we defined as eligible patients those who were registered with the practice for the full year and were aged 18 years or over in that year. From these patients, using relevant Read codes for type 2 diabetes (e.g. C10F.00: Type 2 diabetes mellitus) and excluding those treated with insulin within 2 years of diagnosis, we identified 246,544 patients over the study period. Diagnoses were not constrained to the study period and a relevant code prior to the study as well as during the study period would flag a patient from the respective year onwards. Data on sex, age and removal from the database due to deaths were available and complete for all patients.We extracted data on diabetes-related macrovascular (myocardial infarction, stroke, peripheral vascular disease or amputation) and microvascular (retinopathy, neuropathy, nephropathy [chronic kidney disease stages 4–5] or foot ulcer) complications as well as comorbidities (asthma, coronary heart disease, chronic kidney disease [excluded from microvascular analysis], chronic obstructive pulmonary disease, depression, dementia, severe mental illness, heart failure, hypertension, stroke [excluded from macrovascular analysis], cancer, epilepsy, osteoarthritis, osteoporosis and hypothyroidism). Although we aimed to include all conditions associated with diabetes, the choice was partially determined by the domains incentivised under the Quality and Outcomes Framework (QOF), for which accuracy of diagnosis is considered high. Information was also extracted on smoking (never smoked, current, exsmoker and missing data),BMI, HbA1c levels (%), cholesterol levels (mmol/l) and systolic/diastolic BP (mmHg). Biometric measurement data were cleaned and we calculated patient means for each year when more than one relevant record was available. Using product lists we determined prescription prevalence (at least one) for relevant medications: ACE inhibitors, acarbose, α-blockers, anticoagulants, antiplatelet agents, β-blockers, calcium-channel blockers, thiazide diuretics, loop diuretics, dipeptidyl peptidase-4 inhibitors, glucagon-like peptide- 1 agonists, statins and other lipid-lowering drugs, meglitinides , metformin, sulfonylureas and thiazolidinediones. For approximately 60% of the practices, records were linked to Office of National Statistics (ONS) mortality data and we had access to death dates for all their patients. For these, using ICD-10 codes (www.who.int/classifications/icd/en/) we were able to estimate deathslinked to specific causes (underlying or in the top three): diabetes (E10–E16), ischaemic heart disease (I21–I22), stroke (I60–I64) or stroke excluding bleeds (excluding I63).
Evangelos Kontopantelis, David A Springate, David Reeves, Darren M. Aschroff, Martin Rutter, Iain Buchan, Tim Doran, Glucose, blood pressure and cholesterol levels and their relationships to clinical outcomes in type 2 diabetes: a retrospective cohort study. Diabetologia, 58:505-518, 2015.
Code | Description | Coding System (CPRD_product_code) | Entity type | Category |
---|---|---|---|---|
1021 | INNOZIDE tablets [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
10316 | COAPROVEL tablets 150mg + 12.5mg [SANOFI BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
10323 | losartan with hydrochlorothiazide tablets 100mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
10627 | CO-BETALOC tablets 100mg + 12.5mg [PHARMACIA] | CPRD_product_code | res9: diuretics_thiazide | drug |
10902 | captopril with hydrochlorothiazide tablets 50mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11133 | hydrochlorothiazide with captopril tablets 25mg + 50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1124 | TENORETIC tablets 100mg + 25mg [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
1125 | NAVIDREX -K tablets [NOV/CIBA] | CPRD_product_code | res9: diuretics_thiazide | drug |
11338 | bendroflumethiazide with nadolol tablets 5mg + 40mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11351 | co-zidocapt (hydrochlorothiazide and captopril) tablets 25mg + 50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11384 | co-flumactone (hydroflumethiazide and spironolactone) tablets 50mg+50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11448 | irbesartan with hydrochlorothiazide tablets 150mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11469 | irbesartan with hydrochlorothiazide tablets 300mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11526 | COAPROVEL tablets 300mg + 12.5mg [SANOFI BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
11561 | co-zidocapt (hydrochlorothiazide and captopril) tablets 12.5mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11641 | captopril with hydrochlorothiazide tablets 25mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1170 | cyclopenthiazide tablets 0.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
11864 | valsartan with hydrochlorothiazide tablets 160mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
12054 | propranolol with bendroflumethiazide capsules 80mg + 2.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1209 | NEO-NACLEX tablets 5mg [GOLDSHIELD] | CPRD_product_code | res9: diuretics_thiazide | drug |
1211 | bendroflumethiazide with potassium modified release tablet 2.5mg + 8.4mmol | CPRD_product_code | res9: diuretics_thiazide | drug |
12110 | hydroflumethiazide tablets 50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1213 | NEO-NACLEX -K tablets [MERCURY] | CPRD_product_code | res9: diuretics_thiazide | drug |
12360 | NEPHRIL tablets 1mg [PFIZER] | CPRD_product_code | res9: diuretics_thiazide | drug |
12440 | HYDROSALURIC tablets 25mg [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
1251 | MODURET 25 tablets [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
12517 | timolol maleate with bendroflumethiazide tablets 20mg + 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
12546 | KALSPARE tablets [DOMINION] | CPRD_product_code | res9: diuretics_thiazide | drug |
12547 | triamterene with chlortalidone tablets 50mg + 50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
12651 | timolol maleate with bendroflumethiazide tablets 10mg + 2.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1288 | TENORET tablets 50mg + 12.5mg [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
12926 | polythiazide tablets 1mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1297 | ALDACTIDE film coated tablets 50mg + 50mg [PHARMACIA] | CPRD_product_code | res9: diuretics_thiazide | drug |
13246 | chlorothiazide oral suspension 150mg/5ml | CPRD_product_code | res9: diuretics_thiazide | drug |
13363 | ESIDREX tablets 50mg [NOV/CIBA] | CPRD_product_code | res9: diuretics_thiazide | drug |
13525 | HYDRENOX tablets 50mg [KNOLL] | CPRD_product_code | res9: diuretics_thiazide | drug |
13526 | ATENIXCO tablets 100mg + 25mg [ASHBOURNE] | CPRD_product_code | res9: diuretics_thiazide | drug |
13871 | co-prenozide (oxprenolol and cyclopenthiazide) modified release tablet 160mg + 0.25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
14126 | acebutolol hydrochloride and hydrochlorothiazide tablets 200mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
14228 | COVERSYL PLUS tablets [SERVIER] | CPRD_product_code | res9: diuretics_thiazide | drug |
14283 | valsartan with hydrochlorothiazide tablets 160mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
14438 | CORGARETIC 80 tablets [SANOFI S] | CPRD_product_code | res9: diuretics_thiazide | drug |
14738 | hydrochlorothiazide with losartan tablets 12.5mg + 50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
14870 | telmisartan with hydrochlorothiazide tablets 40mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
15031 | ACCURETIC tablets 10mg + 12.5mg [PFIZER] | CPRD_product_code | res9: diuretics_thiazide | drug |
15108 | quinapril and hydrochlorothiazide tablets 10mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
15127 | hydrochlorothiazide with triamterene tablets 25mg+50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
15135 | hydrochlorothiazide with captopril tablets 12.5mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1520 | CAPOZIDE tablets [SQUIBB] | CPRD_product_code | res9: diuretics_thiazide | drug |
15457 | BAYCARON tablets 25mg [BAYER] | CPRD_product_code | res9: diuretics_thiazide | drug |
15488 | metoprolol tartrate with chlortalidone tablets | CPRD_product_code | res9: diuretics_thiazide | drug |
15811 | co-flumactone (hydroflumethiazide and spironolactone) tablets 25mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
16060 | valsartan with hydrochlorothiazide tablets 80mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
16161 | telmisartan with hydrochlorothiazide tablets 80mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
16498 | KALSPARE tablets [DHP] | CPRD_product_code | res9: diuretics_thiazide | drug |
16632 | HYDROSALURIC tablets 50mg [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
16786 | chlortalidone with atenolol tablets 25mg+100mg | CPRD_product_code | res9: diuretics_thiazide | drug |
17143 | mefruside tablets 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
1721 | DYAZIDE tablets [MERCURY] | CPRD_product_code | res9: diuretics_thiazide | drug |
17252 | ESIDREX tablets 25mg [NOV/CIBA] | CPRD_product_code | res9: diuretics_thiazide | drug |
17561 | bendroflumethiazide with potassium modified release tablet 2.5mg + 7.7mmol | CPRD_product_code | res9: diuretics_thiazide | drug |
17655 | CARACE 10 plus tablets [BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
17689 | MICARDIS PLUS tablets 80mg + 12.5mg [BOEH INGL] | CPRD_product_code | res9: diuretics_thiazide | drug |
17720 | SALURIC tablets 500mg [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
1788 | atenolol with chlortalidone tablets 100mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
18200 | olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
18202 | MICARDIS PLUS tablets 40mg + 12.5mg [BOEH INGL] | CPRD_product_code | res9: diuretics_thiazide | drug |
18263 | ACEZIDE tablets [SQUIBB] | CPRD_product_code | res9: diuretics_thiazide | drug |
18267 | ENDURON tablets 5mg [ABBOTT] | CPRD_product_code | res9: diuretics_thiazide | drug |
18287 | CO-BETALOC SA tablets 200mg + 25mg [PHARMACIA] | CPRD_product_code | res9: diuretics_thiazide | drug |
18361 | AMILMAXCO tablets [ASHBOURNE] | CPRD_product_code | res9: diuretics_thiazide | drug |
18606 | diltiazem and hydrochlorothiazide modified release capsules 150mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
18726 | TRIAMAXCO tablets [ASHBOURNE] | CPRD_product_code | res9: diuretics_thiazide | drug |
18733 | co-amilozide (amiloride and hydrochlorothiazide) oral solution 5mg + 50mg/5ml | CPRD_product_code | res9: diuretics_thiazide | drug |
18743 | TENBEN capsules 25mg + 1.25mg [GALEN] | CPRD_product_code | res9: diuretics_thiazide | drug |
18903 | olmesartan medoxomil with hydrochlorothiazide tablets 20mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
18973 | CENTYL tablets 2.5mg [BURGESS] | CPRD_product_code | res9: diuretics_thiazide | drug |
19055 | chlortalidone with atenolol tablets 12.5mg+50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
19142 | bendroflumethiazide with timolol maleate tablets 2.5mg + 10mg | CPRD_product_code | res9: diuretics_thiazide | drug |
19890 | hydrochlorothiazide with amiloride tablets 25mg+2.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
2 | bendroflumethiazide tablets 2.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
2001 | ALDACTIDE film coated tablets 25mg + 25mg [PHARMACIA] | CPRD_product_code | res9: diuretics_thiazide | drug |
2002 | amiloride hydrochloride with hydrochlorothiazide tablets 5mg + 50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
20057 | methyclothiazide tablets 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
20066 | AMIL-CO tablets 5mg + 50mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
20093 | metoprolol tartrate with hydrochlorothiazide modified release tablet 200mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
20426 | CENTYL K tablets 2.5mg + 7.7mmol [BURGESS] | CPRD_product_code | res9: diuretics_thiazide | drug |
20431 | CENTYL K tablets 2.5mg + 7.7mmol [LEO] | CPRD_product_code | res9: diuretics_thiazide | drug |
2046 | NAVIDREX tablets 0.5mg [MERCURY] | CPRD_product_code | res9: diuretics_thiazide | drug |
21025 | PRESTIM FORTE tablets [LEO] | CPRD_product_code | res9: diuretics_thiazide | drug |
21182 | hydrochlorothiazide with timolol and amiloride tablets 25mg + 10mg + 2.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
21231 | CARALPHA tablets 20mg + 12.5mg [ACTAVIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
21423 | COZAAR-COMP tablets 100mg + 25mg [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
21803 | BERKOZIDE tablets 2.5mg [BERK] | CPRD_product_code | res9: diuretics_thiazide | drug |
21867 | BERKOZIDE tablets 5mg [BERK] | CPRD_product_code | res9: diuretics_thiazide | drug |
21873 | ATENIXCO tablets 50mg+12.5mg [ASHBOURNE] | CPRD_product_code | res9: diuretics_thiazide | drug |
2255 | NAVISPARE tablets [MERCURY] | CPRD_product_code | res9: diuretics_thiazide | drug |
22912 | bendroflumethiazide with propranolol capsules 2.5mg + 80mg | CPRD_product_code | res9: diuretics_thiazide | drug |
22923 | hydrochlorothiazide with amiloride tablets 50mg + 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
23131 | bendroflumethiazide with propranolol modified release capsules 5mg + 160mg | CPRD_product_code | res9: diuretics_thiazide | drug |
23134 | nadolol with bendroflumethiazide tablets 40mg + 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
23427 | BENDROFLUMETHIAZIDE tablets 5mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
23456 | hydrochlorothiazide with valsartan tablets 25mg + 160mg | CPRD_product_code | res9: diuretics_thiazide | drug |
23505 | ADIZEM XL PLUS controlled release capsules 150mg + 12.5mg [NAPP] | CPRD_product_code | res9: diuretics_thiazide | drug |
24008 | VASETIC tablets [SHIRE] | CPRD_product_code | res9: diuretics_thiazide | drug |
24189 | NEO-BENDROMAX tablets 2.5mg [ASHBOURNE] | CPRD_product_code | res9: diuretics_thiazide | drug |
24190 | NEO-BENDROMAX tablets 5mg [ASHBOURNE] | CPRD_product_code | res9: diuretics_thiazide | drug |
24268 | hydrochlorothiazide with valsartan tablets 12.5mg + 80mg | CPRD_product_code | res9: diuretics_thiazide | drug |
24280 | TOTARETIC tablets 100mg+25mg [CP PHARM] | CPRD_product_code | res9: diuretics_thiazide | drug |
24484 | hydrochlorothiazide with valsartan tablets 12.5mg + 160mg | CPRD_product_code | res9: diuretics_thiazide | drug |
24632 | hydrochlorothiazide with losartan tablets 25mg + 100mg | CPRD_product_code | res9: diuretics_thiazide | drug |
25363 | PRESTIM tablets [MEDA] | CPRD_product_code | res9: diuretics_thiazide | drug |
25382 | CO-DIOVAN tablets 160mg + 25mg [NOVARTIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
25500 | HYPERTANE 50 tablets [SCHWARZ] | CPRD_product_code | res9: diuretics_thiazide | drug |
25505 | SPIRO-CO tablets 50mg+50mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
25730 | timolol maleate with amiloride and hydrochlorothiazide tablets | CPRD_product_code | res9: diuretics_thiazide | drug |
2612 | indapamide tablets 2.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
26219 | ZIDA-CO tablets 5mg + 50mg [OPUS] | CPRD_product_code | res9: diuretics_thiazide | drug |
26220 | DELVAS tablets [BERK] | CPRD_product_code | res9: diuretics_thiazide | drug |
26248 | TENCHLOR tablets 100mg + 25mg [BERK] | CPRD_product_code | res9: diuretics_thiazide | drug |
26256 | OPUMIDE tablets 2.5mg [OPUS] | CPRD_product_code | res9: diuretics_thiazide | drug |
26275 | NINDAXA tablets 2.5mg [ASHBOURNE] | CPRD_product_code | res9: diuretics_thiazide | drug |
26741 | TOTARETIC tablets 50mg+12.5mg [CP PHARM] | CPRD_product_code | res9: diuretics_thiazide | drug |
27256 | BENDROFLUMETHIAZIDE tablets 2.5mg [WOCKHARDT] | CPRD_product_code | res9: diuretics_thiazide | drug |
27520 | OLMETEC PLUS tablets 20mg + 25mg [DAIIC-SANK] | CPRD_product_code | res9: diuretics_thiazide | drug |
27689 | BENDROFLUMETHIAZIDE tablets 2.5mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
27946 | nadolol with bendroflumethiazide tablets 80mg + 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
27957 | NATRAMID tablets 2.5mg [TRINITY] | CPRD_product_code | res9: diuretics_thiazide | drug |
28157 | KALSPARE LS tablets [DOMINION] | CPRD_product_code | res9: diuretics_thiazide | drug |
28177 | hydrochlorothiazide with atenolol and amiloride capsules | CPRD_product_code | res9: diuretics_thiazide | drug |
2833 | cyclopenthiazide -k tablets | CPRD_product_code | res9: diuretics_thiazide | drug |
29427 | hydrochlorothiazide with metoprolol tartrate tablets 12.5mg + 100mg | CPRD_product_code | res9: diuretics_thiazide | drug |
29529 | hydroflumethiazide with spironolactone tablets 25mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
29634 | OLMETEC PLUS tablets 20mg + 12.5mg [DAIIC-SANK] | CPRD_product_code | res9: diuretics_thiazide | drug |
2979 | CENTYL K tablets [BURGESS] | CPRD_product_code | res9: diuretics_thiazide | drug |
2982 | ZESTORETIC 20-tablets 20mg + 12.5mg [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
29991 | CENTYL tablets 5mg [BURGESS] | CPRD_product_code | res9: diuretics_thiazide | drug |
30272 | benzthiazide with triamterene capsules | CPRD_product_code | res9: diuretics_thiazide | drug |
30519 | amiloride hydrochloride with timolol and hydrochlorothiazide tablets | CPRD_product_code | res9: diuretics_thiazide | drug |
3056 | NATRILIX SR sustained release tablets 1.5mg [SERVIER] | CPRD_product_code | res9: diuretics_thiazide | drug |
31131 | SPIRO-CO tablets 25mg+25mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
31150 | CO-AMILOZIDE tablets 5mg+50mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
31470 | TENCHLOR tablets 50mg+12.5mg [BERK] | CPRD_product_code | res9: diuretics_thiazide | drug |
31670 | BENDROFLUMETHIAZIDE tablets 2.5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
31708 | CO-TENIDONE tablets 50mg+12.5mg [ACTAVIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
31820 | BENDROFLUMETHIAZIDE tablets 5mg [WOCKHARDT] | CPRD_product_code | res9: diuretics_thiazide | drug |
3203 | CAPOZIDE LS tablets [SQUIBB] | CPRD_product_code | res9: diuretics_thiazide | drug |
32094 | CO-TENIDONE tablets 50mg+12.5mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
32166 | CAPTO-CO tablets 25mg+50mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
3293 | MODURETIC solution [BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
33083 | INDAPAMIDE tablets 2.5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
33353 | LISINOPRIL AND HYDROCHLOROTHIAZIDE tablets 20mg + 12.5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
33415 | BENDROFLUMETHIAZIDE tablets 2.5mg [GEN (UK)] | CPRD_product_code | res9: diuretics_thiazide | drug |
33651 | BENDROFLUMETHIAZIDE tablets 2.5mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
33659 | hydrochlorothiazide with metoprolol tartrate modified release tablet 25mg + 200mg | CPRD_product_code | res9: diuretics_thiazide | drug |
33724 | DIURIL oral suspension 250mg/5ml [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
34012 | CO-TENIDONE tablets 100mg+25mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
34034 | CO-TENIDONE tablets 50mg+12.5mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
34059 | BENDROFLUMETHIAZIDE tablets 2.5mg [ACTAVIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
34124 | BENDROFLUMETHIAZIDE tablets 5mg [ACTAVIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
34367 | CO-AMILOZIDE tablets 2.5mg+25mg [WOCKHARDT] | CPRD_product_code | res9: diuretics_thiazide | drug |
34449 | CO-TENIDONE tablets 50mg+12.5mg [GEN (UK)] | CPRD_product_code | res9: diuretics_thiazide | drug |
34551 | INDAPAMIDE tablets 2.5mg [GEN (UK)] | CPRD_product_code | res9: diuretics_thiazide | drug |
34602 | BENDROFLUMETHIAZIDE tablets 2.5mg [SOVEREIGN] | CPRD_product_code | res9: diuretics_thiazide | drug |
348 | MODURETIC tablets [BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
34803 | BENDROFLUMETHIAZIDE tablets 2.5mg [REGENT] | CPRD_product_code | res9: diuretics_thiazide | drug |
34825 | CO-TENIDONE tablets 50mg+12.5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
34899 | CO-TENIDONE tablets 100mg+25mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
3517 | hydrochlorothiazide tablets 50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
35196 | COAPROVEL tablets 300mg + 25mg [SANOFI BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
3526 | amiloride hydrochloride with atenolol and hydrochlorothiazide capsules | CPRD_product_code | res9: diuretics_thiazide | drug |
35380 | hydrochlorothiazide with olmesartan medoxomil tablets 12.5mg + 20mg | CPRD_product_code | res9: diuretics_thiazide | drug |
35481 | irbesartan with hydrochlorothiazide tablets 300mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
36519 | ESIDREX -K tablets [NOV/CIBA] | CPRD_product_code | res9: diuretics_thiazide | drug |
3701 | amiloride hydrochloride with hydrochlorothiazide tablets 2.5mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
37294 | triamterene with chlortalidone tablets 50mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
37650 | losartan with hydrochlorothiazide tablets 100mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
37710 | LISINOPRIL AND HYDROCHLOROTHIAZIDE tablets 10mg + 12.5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
37725 | CO-TENIDONE tablets 100mg+25mg [GEN (UK)] | CPRD_product_code | res9: diuretics_thiazide | drug |
37747 | COZAAR-COMP tablets 100mg + 12.5mg [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
37908 | COVERSYL ARGININE PLUS tablets 5mg + 1.25mg [SERVIER] | CPRD_product_code | res9: diuretics_thiazide | drug |
37978 | perindopril arginine with indapamide tablets 5mg + 1.25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
38367 | hydrochlorothiazide with losartan tablets 12.5mg + 100mg | CPRD_product_code | res9: diuretics_thiazide | drug |
38459 | telmisartan with hydrochlorothiazide tablets 80mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
38889 | MICARDIS PLUS tablets 80mg + 25mg [BOEH INGL] | CPRD_product_code | res9: diuretics_thiazide | drug |
38995 | ZESTORETIC 20 tablets [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
39021 | hydrochlorothiazide with olmesartan medoxomil tablets 25mg + 20mg | CPRD_product_code | res9: diuretics_thiazide | drug |
39137 | ZESTORETIC 10 tablets [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
39147 | CARACE 20 PLUS tablets [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
39227 | CAPOZIDE LS tablets [BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
39242 | CARACE 10 PLUS tablets [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
39447 | VARBIM XL prolonged release tablet 1.5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
40149 | BENDROFLUMETHIAZIDE tablets 5mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
4034 | amiloride hydrochloride with hydrochlorothiazide solution 5mg + 50mg/5ml | CPRD_product_code | res9: diuretics_thiazide | drug |
4044 | DIUREXAN tablets 20mg [MEDA] | CPRD_product_code | res9: diuretics_thiazide | drug |
40886 | BENDROFLUMETHIAZIDE tablets 2.5mg [ALMUS] | CPRD_product_code | res9: diuretics_thiazide | drug |
40907 | INDAPAMIDE tablets 2.5mg [GENUS] | CPRD_product_code | res9: diuretics_thiazide | drug |
41517 | BENDROFLUMETHIAZIDE tablets 5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
41556 | CO-AMILOZIDE tablets 5mg+50mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
41572 | CO-TENIDONE tablets 100mg+25mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
41861 | TENSAID XL tablets 1.5mg [GEN (UK)] | CPRD_product_code | res9: diuretics_thiazide | drug |
41885 | ETHIBIDE XL prolonged release tablet 1.5mg [GENUS] | CPRD_product_code | res9: diuretics_thiazide | drug |
42142 | MODURETIC tablets [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
42906 | INDAPAMIDE tablets 2.5mg [NICHE] | CPRD_product_code | res9: diuretics_thiazide | drug |
43184 | MAPEMID XL prolonged release tablet 1.5mg [RATIOPHARM] | CPRD_product_code | res9: diuretics_thiazide | drug |
4332 | metolazone tablets 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
43322 | olmesartan medoxomil with hydrochlorothiazide tablets 40mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
43516 | INDAPAMIDE tablets 2.5mg [ACTAVIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
43915 | OLMETEC PLUS tablets 40mg + 12.5mg [DAIIC-SANK] | CPRD_product_code | res9: diuretics_thiazide | drug |
44168 | INDIPAM XL prolonged release tablet 1.5mg [ACTAVIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
4429 | TRASIDREX tablets [GOLDSHIELD] | CPRD_product_code | res9: diuretics_thiazide | drug |
4540 | COZAAR-COMP tablets 50mg + 12.5mg [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
45916 | hydroflumethiazide with spironolactone tablets 50mg+50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
4605 | MODUCREN tablets [M S D] | CPRD_product_code | res9: diuretics_thiazide | drug |
46302 | NEO-NACLEX tablets 2.5mg [MERCURY] | CPRD_product_code | res9: diuretics_thiazide | drug |
46355 | SEVIKAR HCT tablets 20mg + 5mg + 12.5mg [DAIIC-SANK] | CPRD_product_code | res9: diuretics_thiazide | drug |
46675 | INDAPAMIDE SR tablets 1.5mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
46687 | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 20mg + 5mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
46715 | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 10mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
46792 | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 5mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
46916 | CO-AMILOZIDE tablets 5mg+50mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
46952 | CO-TENIDONE tablets 100mg+25mg [ACTAVIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
47467 | olmesartan medoxomil with amlodipine and hydrochlorothiazide tablets 40mg + 5mg + 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
47573 | SEVIKAR HCT tablets 40mg + 5mg + 12.5mg [DAIIC-SANK] | CPRD_product_code | res9: diuretics_thiazide | drug |
47616 | SEVIKAR HCT tablets 40mg + 10mg + 12.5mg [DAIIC-SANK] | CPRD_product_code | res9: diuretics_thiazide | drug |
47727 | SEVIKAR HCT tablets 40mg + 5mg + 25mg [DAIIC-SANK] | CPRD_product_code | res9: diuretics_thiazide | drug |
47804 | CO-TRIAMTERZIDE tablets 50mg+25mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
47844 | BENDROFLUMETHIAZIDE tablets 2.5mg [KENT] | CPRD_product_code | res9: diuretics_thiazide | drug |
4796 | INDERETIC capsules [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
48039 | LOSARTAN WITH HYDROCHLOROTHIAZIDE tablets 100mg + 12.5mg [TEVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
48079 | INDAPAMIDE tablets 2.5mg [ZENTIVA] | CPRD_product_code | res9: diuretics_thiazide | drug |
48098 | perindopril erbumine with indapamide (roi) tablets 4mg + 1.25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
48099 | INDAPAMIDE tablets 2.5mg [HILLCROSS] | CPRD_product_code | res9: diuretics_thiazide | drug |
48132 | hydrochlorothiazide capsules | CPRD_product_code | res9: diuretics_thiazide | drug |
4983 | atenolol with amiloride and hydrochlorothiazide capsules | CPRD_product_code | res9: diuretics_thiazide | drug |
5112 | indapamide modified release tablet 1.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
5189 | enalapril with hydrochlorothiazide tablets 20mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
5330 | CORGARETIC 40 tablets [SANOFI S] | CPRD_product_code | res9: diuretics_thiazide | drug |
5416 | co-triamterzide (triamterene and hydrochlorothiazide) tablets 50mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
542 | hydrochlorothiazide tablets 25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
5721 | co-tenidone (atenolol and chlortalidone) tablets 100mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
5727 | cyclopenthiazide with amiloride tablets 250micrograms + 2.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
58 | bendroflumethiazide tablets 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
581 | atenolol with chlortalidone tablets 50mg+12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
6359 | ZESTORETIC 10-tablets 10mg + 12.5mg [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
6437 | losartan with hydrochlorothiazide tablets 50mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
6468 | lisinopril with hydrochlorothiazide tablets 20mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
6786 | lisinopril with hydrochlorothiazide tablets 10mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
6794 | perindopril erbumine with indapamide tablets 4mg + 1.25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
6816 | chlorothiazide oral suspension 250mg/5ml | CPRD_product_code | res9: diuretics_thiazide | drug |
6877 | CO-DIOVAN tablets 160mg + 12.5mg [NOVARTIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
7066 | metoprolol tartrate with hydrochlorothiazide tablets 100mg + 12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
7136 | DYTIDE capsules 50mg+25mg [GOLDSHIELD] | CPRD_product_code | res9: diuretics_thiazide | drug |
7351 | bendroflumethiazide oral suspension 2.5mg/5ml | CPRD_product_code | res9: diuretics_thiazide | drug |
7543 | KALTEN capsules [M&A PHARM] | CPRD_product_code | res9: diuretics_thiazide | drug |
7618 | xipamide tablets 20mg | CPRD_product_code | res9: diuretics_thiazide | drug |
764 | CO-DIOVAN tablets 80mg + 12.5mg [NOVARTIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
7641 | NATRILIX tablets 2.5mg [SERVIER] | CPRD_product_code | res9: diuretics_thiazide | drug |
7698 | APRINOX tablets 5mg [SOVEREIGN] | CPRD_product_code | res9: diuretics_thiazide | drug |
7740 | triamterene with benzthiazide capsules 50mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
7961 | spironolactone with hydroflumethiazide tablets 50mg+50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
8058 | NORMETIC tablets [ABBOTT] | CPRD_product_code | res9: diuretics_thiazide | drug |
8147 | LOPRESORETIC tablets [NOV/GEIGY] | CPRD_product_code | res9: diuretics_thiazide | drug |
8189 | SECADREX tablets [AVENTIS] | CPRD_product_code | res9: diuretics_thiazide | drug |
8303 | TENAVOID tablets [BURGESS] | CPRD_product_code | res9: diuretics_thiazide | drug |
8369 | INDEREX capsules [ASTRAZENEC] | CPRD_product_code | res9: diuretics_thiazide | drug |
8464 | meprobamate with bendroflumethiazide tablets | CPRD_product_code | res9: diuretics_thiazide | drug |
8521 | spironolactone with hydroflumethiazide tablets 25mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
8526 | APRINOX tablets 2.5mg [SOVEREIGN] | CPRD_product_code | res9: diuretics_thiazide | drug |
8602 | METENIX tablets 5mg [SANOFI/AVE] | CPRD_product_code | res9: diuretics_thiazide | drug |
8623 | PRESTIM tablets [ICN] | CPRD_product_code | res9: diuretics_thiazide | drug |
8673 | oxprenolol with cyclopenthiazide modified release tablet 160mg+0.25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
8836 | chlorothiazide tablets 500mg | CPRD_product_code | res9: diuretics_thiazide | drug |
8891 | HYGROTON -K tablets [NOV/GEIGY] | CPRD_product_code | res9: diuretics_thiazide | drug |
8897 | TRIAM-CO tablets 50mg+25mg [IVAX] | CPRD_product_code | res9: diuretics_thiazide | drug |
8987 | propranolol with bendroflumethiazide modified release capsules 160mg + 5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
9178 | atenolol with bendroflumethiazide capsules 25mg + 1.25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
9223 | triamterene with hydrochlorothiazide tablets 50mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
923 | co-amilozide (amiloride and hydrochlorothiazide) tablets 5mg+50mg | CPRD_product_code | res9: diuretics_thiazide | drug |
924 | co-amilozide (amiloride and hydrochlorothiazide) tablets 2.5mg+25mg | CPRD_product_code | res9: diuretics_thiazide | drug |
9764 | CARACE 20 plus tablets [BMS] | CPRD_product_code | res9: diuretics_thiazide | drug |
9783 | co-tenidone (atenolol and chlortalidone) tablets 50mg+12.5mg | CPRD_product_code | res9: diuretics_thiazide | drug |
To Export Phenotype Details:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH521/version/1042/detail/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH521/version/1042/detail/?format=json |
R Package |
|
To Export Phenotype Code List:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH521/version/1042/export/codes/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH521/version/1042/export/codes/?format=json |
CSV | site_root/phenotypes/PH521/version/1042/export/codes/ |
R Package |
|
Version ID |
Name | Owner | Publish date | |
---|---|---|---|---|
1042 | Diuretics Thiazide | ieuan.scanlon | 2021-10-06 | currently shown |
Export - export all codes into a csv file/JSON/XML for the current phenotype version.
Print - Print page.