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Lithium Therapy

Evangelos Kontopantelis, David Springate, David Reeves, Darren M Ashcroft, Jose M Valderas, Tim Doran

Type
Drug
ID
PH542
Version ID
1084
Data Sources
Valid event data range
01/04/2004 - 31/03/2021
Sex
Female, Male
Agreement Date
2014-01-27
Coding system
Read codes v2 OXMIS codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

The study period extended from 1 April 2004, the date of introduction of the incentivisation scheme, to 31 March 2012. Practices’ performance under the QOF is measured over a financial year, so we divided the study period into eight financial years (1 April to 31 March the following year). Not all 644 practices provided research standard data (as assessed by the CPRD assessment algorithm) for the whole period. Within each year, we identified practices that reliably contributed data for the whole year. Our main dataset comprised this group of practices, which varies over time. We also generated two alternative datasets with which to assess the sensitivity of our findings. For the first, we included 452 practices that were continuously active and up to standard for the whole of the study period; for the second, we selected a subsample of 50 practices that were most representative of UK practices in terms of list sizes of patients and area deprivation according to the Index of Multiple Deprivation,13 14 two of the most important predictors of QOF performance.12 15 16 In each of the three datasets, for each financial year, we defined “eligible” patients as those registered with an included practice for the full year.

Publications

  • Evangelos Kontopantelis, David Springate, David Reeves, Darren M Ashcroft, Jose M Valderas, Tim Doran, Withdrawing performance indicators: retrospective analysis of general practice performance under UK Quality and Outcomes Framework. BMJ, 348:g330, 2014.

Clinical Code List

Rows: 13
Code Description Entity type Coding System (OXMIS Read) Category
44W8.00 Serum lithium level lithium_therapy Read diagnostic
44W8.11 Lithium: blood level lithium_therapy Read diagnostic
44W8000 Lithium level therapeutic lithium_therapy Read diagnostic
44W8100 Lithium level high - toxic lithium_therapy Read diagnostic
44W8200 Lithium level low lithium_therapy Read diagnostic
44vE.00 Lithium level therapeutic lithium_therapy Read diagnostic
6657.00 On lithium lithium_therapy Read diagnostic
6657.11 Lithium monitoring lithium_therapy Read diagnostic
6657.12 Started lithium lithium_therapy Read diagnostic
665B.00 Lithium stopped lithium_therapy Read diagnostic
9859 TOXICITY LITHIUM lithium_therapy Read diagnostic
R105300 [D]Lithium; blood level abnormal lithium_therapy Read diagnostic
T3551CA LITHIUM THERAPY lithium_therapy Read diagnostic
Rows: 5
Code Description Entity type Coding System (OXMIS Read) Category
L 130L SERUM LITHIUM LEVEL lithium_therapy OXMIS diagnostic
L 130LA LITHIUM LEVEL lithium_therapy OXMIS diagnostic
L 130LB LITHIUM LEVEL LOW lithium_therapy OXMIS diagnostic
L 130LC LITHIUM LEVEL THERAPEUTIC lithium_therapy OXMIS diagnostic
L 130LD LITHIUM LEVEL HIGH lithium_therapy OXMIS diagnostic

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH542/version/1084/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH542/version/1084/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH542', '1084', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH542/version/1084/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH542/version/1084/export/codes/?format=json
CSV site_root/phenotypes/PH542/version/1084/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH542', '1084', api_client=client)

Version History

Version
ID
Name Owner Publish date
1084 Lithium Therapy ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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