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Thyroid Function

Evangelos Kontopantelis, David Springate, David Reeves, Darren M Ashcroft, Jose M Valderas, Tim Doran

ID
PH568
Version ID
1136
Type
Disease or Syndrome
Data Sources
Valid event data range
01/04/2004 - 31/03/2021
Sex
♀  Female ♂  Male
Agreement Date
2014-01-27
Coding system
Read codes v2 OXMIS codes
Collections
ClinicalCodes Repository Phenotype Library
Tags
No tags

Definition

The study period extended from 1 April 2004, the date of introduction of the incentivisation scheme, to 31 March 2012. Practices’ performance under the QOF is measured over a financial year, so we divided the study period into eight financial years (1 April to 31 March the following year). Not all 644 practices provided research standard data (as assessed by the CPRD assessment algorithm) for the whole period. Within each year, we identified practices that reliably contributed data for the whole year. Our main dataset comprised this group of practices, which varies over time. We also generated two alternative datasets with which to assess the sensitivity of our findings. For the first, we included 452 practices that were continuously active and up to standard for the whole of the study period; for the second, we selected a subsample of 50 practices that were most representative of UK practices in terms of list sizes of patients and area deprivation according to the Index of Multiple Deprivation,13 14 two of the most important predictors of QOF performance.12 15 16 In each of the three datasets, for each financial year, we defined “eligible” patients as those registered with an included practice for the full year.

Publications

  • Evangelos Kontopantelis, David Springate, David Reeves, Darren M Ashcroft, Jose M Valderas, Tim Doran, Withdrawing performance indicators: retrospective analysis of general practice performance under UK Quality and Outcomes Framework. BMJ, 348:g330, 2014.

Clinical Code List

Rows: 58
Code Description Entity type Coding System (OXMIS Read) Category
442..00 Thyroid hormone tests Thyroid_function Read diagnostic
442..11 TRH level Thyroid_function Read diagnostic
442..12 TSH level Thyroid_function Read diagnostic
442..13 Thyroid function tests Thyroid_function Read diagnostic
442..14 Thyroxine binding globulin Thyroid_function Read diagnostic
4421.00 Thyroid hormone tests normal Thyroid_function Read diagnostic
4421.11 Euthyroid Thyroid_function Read diagnostic
4422.00 Thyroid hormone tests high Thyroid_function Read diagnostic
4423.00 Thyroid hormone tests low Thyroid_function Read diagnostic
4424.00 Serum T3 level Thyroid_function Read diagnostic
4424000 Serum T3 level normal Thyroid_function Read diagnostic
4424100 Serum T3 level high Thyroid_function Read diagnostic
4424200 Serum T3 level low Thyroid_function Read diagnostic
4425.00 Free T3 level Thyroid_function Read diagnostic
4426.00 Serum T4 level Thyroid_function Read diagnostic
4426000 Serum T4 level normal Thyroid_function Read diagnostic
4426100 Serum T4 level abnormal Thyroid_function Read diagnostic
4427.00 Free T4 level Thyroid_function Read diagnostic
4428.00 Free thyroxine index Thyroid_function Read diagnostic
4429.00 Thyroxine binding globulin-TBG Thyroid_function Read diagnostic
442A.00 TSH - thyroid stim. hormone Thyroid_function Read diagnostic
442A000 Serum TSH level normal Thyroid_function Read diagnostic
442A100 Serum TSH level abnormal Thyroid_function Read diagnostic
442B.00 TRH - thyroid release. hormone Thyroid_function Read diagnostic
442C.00 Thyroid horm tests borderline Thyroid_function Read diagnostic
442D.00 T3 uptake test Thyroid_function Read diagnostic
442D000 T3 uptake test normal Thyroid_function Read diagnostic
442D100 T3 uptake test abnormal Thyroid_function Read diagnostic
442E.00 PBI - protein bound iodine estimation Thyroid_function Read diagnostic
442F.00 T3 suppression test Thyroid_function Read diagnostic
442G.00 Thyroid hormone tests abnormal Thyroid_function Read diagnostic
442H.00 Thyroid function tests normal Thyroid_function Read diagnostic
442I.00 Thyroid function tests abnormal Thyroid_function Read diagnostic
442J.00 Thyroid function test Thyroid_function Read diagnostic
442K.00 30 minute plasma TSH level Thyroid_function Read diagnostic
442L.00 60 minute plasma TSH level Thyroid_function Read diagnostic
442M.00 90 minute plasma TSH level Thyroid_function Read diagnostic
442N.00 120 minute plasma TSH level Thyroid_function Read diagnostic
442O.00 150 minute plasma TSH level Thyroid_function Read diagnostic
442P.00 30 minute serum TSH level Thyroid_function Read diagnostic
442Q.00 60 minute serum TSH level Thyroid_function Read diagnostic
442S.00 120 minute serum TSH level Thyroid_function Read diagnostic
442T.00 150 minute serum TSH level Thyroid_function Read diagnostic
442U.00 Serum free triiodothyronine level Thyroid_function Read diagnostic
442V.00 Serum free T4 level Thyroid_function Read diagnostic
442W.00 Serum TSH level Thyroid_function Read diagnostic
442X.00 Plasma TSH level Thyroid_function Read diagnostic
442Y.00 Plasma free triiodothyronine level Thyroid_function Read diagnostic
442Z.00 Thyroid hormone tests NOS Thyroid_function Read diagnostic
442a.00 Plasma total T4 level Thyroid_function Read diagnostic
442b.00 Serum total T4 level Thyroid_function Read diagnostic
442c.00 Plasma free T4 level Thyroid_function Read diagnostic
442d.00 Serum thyroglobulin level Thyroid_function Read diagnostic
442e.00 Blood spot TSH level Thyroid_function Read diagnostic
442f.00 Serum total T3 level Thyroid_function Read diagnostic
442g.00 Serum thyroglobulin recovery level Thyroid_function Read diagnostic
R145.00 [D]Thyroid function test abnormal Thyroid_function Read diagnostic
R145z00 [D]Thyroid function tests abnormal NOS Thyroid_function Read diagnostic
Rows: 24
Code Description Entity type Coding System (OXMIS Read) Category
L 112MA SERUM TSH Thyroid_function OXMIS diagnostic
L 112MB SERUM TSH NORMAL Thyroid_function OXMIS diagnostic
L 112MC SERUM TSH ABNORMAL Thyroid_function OXMIS diagnostic
L 112N TSH LEVEL Thyroid_function OXMIS diagnostic
L 112NB TSH LEVEL NORMAL Thyroid_function OXMIS diagnostic
L 112NC TSH LEVEL ABNORMAL Thyroid_function OXMIS diagnostic
L4000T SERUM THYROXINE LEVEL Thyroid_function OXMIS diagnostic
L4000TE THYROXINE ESTIMATION Thyroid_function OXMIS diagnostic
L4021L T4 LEVEL Thyroid_function OXMIS diagnostic
L4021LA T4 LEVEL ABNORMAL Thyroid_function OXMIS diagnostic
L4021LN T4 LEVEL NORMAL Thyroid_function OXMIS diagnostic
L4021PA T4 TOXICOSIS TEST ABNORMAL Thyroid_function OXMIS diagnostic
L4021PN T4 TOXICOSIS TEST NORMAL Thyroid_function OXMIS diagnostic
L4021PV T4 TOXICOSIS TEST Thyroid_function OXMIS diagnostic
L4031 T3 UPTAKE TEST Thyroid_function OXMIS diagnostic
L4031AA T3 UPTAKE TEST ABNORMAL Thyroid_function OXMIS diagnostic
L4031AN T3 UPTAKE TEST NORMAL Thyroid_function OXMIS diagnostic
L4031HS T3 SERUM LEVEL INCREASED Thyroid_function OXMIS diagnostic
L4031LF T3 FREE LEVEL Thyroid_function OXMIS diagnostic
L4031LS T3 SERUM LEVEL DECREASED Thyroid_function OXMIS diagnostic
L4031NM T3 LEVEL Thyroid_function OXMIS diagnostic
L4033F THYROID FUNCTION TEST Thyroid_function OXMIS diagnostic
L4033FA THYROID FUNCTION TEST ABNORMAL Thyroid_function OXMIS diagnostic
L4033FN THYROID FUNCTION TEST NORMAL Thyroid_function OXMIS diagnostic

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH568/version/1136/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH568/version/1136/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH568', '1136', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH568/version/1136/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH568/version/1136/export/codes/?format=json
CSV site_root/phenotypes/PH568/version/1136/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH568', '1136', api_client=client)

Version History

Version
ID
Name Owner Publish date
1136 Thyroid Function ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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