Objective:
To investigate whether there is an association between use of ACE inhibitors (ACEI) and angiotensin receptor blockers (ARB), and risk of acute kidney injury (AKI).
Design:
A time-updated, new-user cohort study among people initiating common antihypertensives (ACEI/ARB, beta-blockers, calcium channel blockers and thiazide diuretics) in primary care between April 1997 and March 2014.
Participants:
Adults initiating antihypertensive drug treatment, with at least one year of registration prior to first prescription, identified from UK primary care practices contributing to the Clinical Practice Research Datalink and eligible for linkage to hospital records data from the Hospital Episode Statistics database.
Main outcome measures:
Incidence rate ratio (RR) for first episode of AKI during time exposed to ACEI/ARB compared to time unexposed, estimated using Poisson regression adjusted for age, sex, comorbidities, use of other antihypertensive drugs, and calendar period.
Results:
Among 570,443 participants with a median follow-up of 2.8 years (IQR 0.4 to 7) there were 15,004 first cases of AKI. The overall crude rate of AKI was 6.4/1,000 person years at risk (95% CI 6.30 to 6.50) but varied from 1.63 (1.43 to 1.86) to 662.53 (538.98 to 814.40) depending on, age, comorbidities, and other prescribed drugs. The adjusted RR of AKI during time exposed to ACEI/ARB compared to time unexposed was 1.18 (95% CI 1.13 to 1.23) which was attenuated to 1.12 (95% CI 1.08 to 1.17) after adjustment for non-thiazide diuretic therapy. There was an interaction for the risk of AKI between people using loop diuretics and ACEI/ARB. For those taking loop diuretics, the adjusted RR of AKI during time exposed to ACEI/ARB compared to time unexposed was 0.99 (95% CI 0.92 to 1.06) but it was 1.18 (95% CI 1.13 to 1.24) among people not-exposed to loop diuretics (p<0.001).
Conclusions:
Treatment with ACEI/ARB alone appears to be associated with a small increase in the rate of AKI which is largely seen among people with low absolute risk of AKI. Among people requiring loop diuretics, who have a high absolute risk of AKI, treatment with ACEI/ARB had no measurable association with AKI.
Kethryn E Mansfield, Dorothea Nitsch, Liam Smeeth, Krishnan Bhaskaram, Laurie A Tomlinson, Renin-angiostensin system blockage and risk of acute kidney injury. 2015.
| Code | Description | Entity type | Category | Coding System (ICD-10 Read) |
|---|---|---|---|---|
| 14A3.00 | h/o: myocardial infarct <60 | res30: Ischaemic heart disease | diagnostic | Read |
| 14A4.00 | h/o: myocardial infarct >60 | res30: Ischaemic heart disease | diagnostic | Read |
| 14A5.00 | h/o: angina pectoris | res30: Ischaemic heart disease | diagnostic | Read |
| 14AA.00 | h/o: heart disease nos | res30: Ischaemic heart disease | diagnostic | Read |
| 14AH.00 | h/o: myocardial infarction in last year | res30: Ischaemic heart disease | diagnostic | Read |
| 14AJ.00 | h/o: angina in last year | res30: Ischaemic heart disease | diagnostic | Read |
| 14AL.00 | h/o: treatment for ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| 14AT.00 | history of myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| 14AW.00 | h/o acute coronary syndrome | res30: Ischaemic heart disease | diagnostic | Read |
| 182A.00 | Chest pain on exertion | res30: Ischaemic heart disease | diagnostic | Read |
| 187..00 | frequency of angina | res30: Ischaemic heart disease | diagnostic | Read |
| 1J61.00 | suspected ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| 3213111 | Positive exercise ECG test | res30: Ischaemic heart disease | diagnostic | Read |
| 322..00 | ecg: myocardial ischaemia | res30: Ischaemic heart disease | diagnostic | Read |
| 3222 | ecg:shows myocardial ischaemia | res30: Ischaemic heart disease | diagnostic | Read |
| 322Z.00 | ecg: myocardial ischaemia nos | res30: Ischaemic heart disease | diagnostic | Read |
| 323..00 | ecg: myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| 3232 | ecg: old myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| 3233 | ecg: antero-septal infarct. | res30: Ischaemic heart disease | diagnostic | Read |
| 3234 | ecg:posterior/inferior infarct | res30: Ischaemic heart disease | diagnostic | Read |
| 3235 | ecg: subendocardial infarct | res30: Ischaemic heart disease | diagnostic | Read |
| 3236 | ecg: lateral infarction | res30: Ischaemic heart disease | diagnostic | Read |
| 323Z.00 | ecg: myocardial infarct nos | res30: Ischaemic heart disease | diagnostic | Read |
| 32B..00 | ecg: q wave | res30: Ischaemic heart disease | diagnostic | Read |
| 32B2.00 | ecg: q wave abnormal | res30: Ischaemic heart disease | diagnostic | Read |
| 32B3.00 | ecg: q wave pathological | res30: Ischaemic heart disease | diagnostic | Read |
| 32BZ.00 | ecg: q wave nos | res30: Ischaemic heart disease | diagnostic | Read |
| 32E4.00 | ecg: s-t depression | res30: Ischaemic heart disease | diagnostic | Read |
| 44H3.00 | cardiac enzymes abnormal | res30: Ischaemic heart disease | diagnostic | Read |
| 44H3000 | cardiac enzymes abnormal - first set | res30: Ischaemic heart disease | diagnostic | Read |
| 44HJ.00 | Plasma creatinine phosphokinase MB isoenzyme level | res30: Ischaemic heart disease | diagnostic | Read |
| 44MH.00 | Plasma troponin T level | res30: Ischaemic heart disease | diagnostic | Read |
| 44p2.00 | cardiac troponin positive | res30: Ischaemic heart disease | diagnostic | Read |
| 5533 | angiocardiography abnormal | res30: Ischaemic heart disease | diagnostic | Read |
| 5543 | coronary arteriograph.abnormal | res30: Ischaemic heart disease | diagnostic | Read |
| 5C11.00 | radionuclide heart study abnormal | res30: Ischaemic heart disease | diagnostic | Read |
| 661M000 | angina self-management plan agreed | res30: Ischaemic heart disease | diagnostic | Read |
| 662..00 | Cardiac disease monitoring | res30: Ischaemic heart disease | diagnostic | Read |
| 662..11 | Heart disease monitoring | res30: Ischaemic heart disease | diagnostic | Read |
| 662K.00 | angina control | res30: Ischaemic heart disease | diagnostic | Read |
| 662K000 | angina control - good | res30: Ischaemic heart disease | diagnostic | Read |
| 662K100 | angina control - poor | res30: Ischaemic heart disease | diagnostic | Read |
| 662K200 | angina control - improving | res30: Ischaemic heart disease | diagnostic | Read |
| 662K300 | angina control - worsening | res30: Ischaemic heart disease | diagnostic | Read |
| 662Kz00 | angina control nos | res30: Ischaemic heart disease | diagnostic | Read |
| 662N.00 | CHD monitoring | res30: Ischaemic heart disease | diagnostic | Read |
| 662Z.00 | Cardiac disease monitoring NOS | res30: Ischaemic heart disease | diagnostic | Read |
| 66f..00 | Cardiovascular disease monitoring | res30: Ischaemic heart disease | diagnostic | Read |
| 66f1.00 | Cardiovascular disease interim monitoring | res30: Ischaemic heart disease | diagnostic | Read |
| 6A2..00 | coronary heart disease annual review | res30: Ischaemic heart disease | diagnostic | Read |
| 6A4..00 | coronary heart disease review | res30: Ischaemic heart disease | diagnostic | Read |
| 792..11 | coronary artery bypass graft operations | res30: Ischaemic heart disease | diagnostic | Read |
| 7920 | saphenous vein graft replacement of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7920.11 | saphenous vein graft bypass of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7920000 | saphenous vein graft replacement of one coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7920100 | saphenous vein graft replacement of two coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7920200 | saphenous vein graft replacement of three coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7920300 | saphenous vein graft replacement of four+ coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7920y00 | saphenous vein graft replacement of coronary artery os | res30: Ischaemic heart disease | diagnostic | Read |
| 7920z00 | saphenous vein graft replacement coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7921 | other autograft replacement of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7921.11 | other autograft bypass of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7921000 | autograft replacement of one coronary artery nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7921100 | autograft replacement of two coronary arteries nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7921200 | autograft replacement of three coronary arteries nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7921300 | autograft replacement of four of more coronary arteries nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7921y00 | other autograft replacement of coronary artery os | res30: Ischaemic heart disease | diagnostic | Read |
| 7921z00 | other autograft replacement of coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7922 | allograft replacement of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7922.11 | allograft bypass of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7922000 | allograft replacement of one coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7922100 | allograft replacement of two coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7922200 | allograft replacement of three coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7922300 | allograft replacement of four or more coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7922y00 | other specified allograft replacement of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7922z00 | allograft replacement of coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7923 | prosthetic replacement of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7923.11 | prosthetic bypass of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7923000 | prosthetic replacement of one coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7923100 | prosthetic replacement of two coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7923200 | prosthetic replacement of three coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7923300 | prosthetic replacement of four or more coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7923z00 | prosthetic replacement of coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7924 | revision of bypass for coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7924000 | revision of bypass for one coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7924100 | revision of bypass for two coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7924200 | revision of bypass for three coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7924y00 | other specified revision of bypass for coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7924z00 | revision of bypass for coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7925 | connection of mammary artery to coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7925.11 | creation of bypass from mammary artery to coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7925000 | double anastomosis of mammary arteries to coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7925100 | double implant of mammary arteries into coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7925300 | single anastomosis of mammary artery to coronary artery nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7925311 | lima single anastomosis | res30: Ischaemic heart disease | diagnostic | Read |
| 7925312 | rima single anastomosis | res30: Ischaemic heart disease | diagnostic | Read |
| 7925400 | single implantation of mammary artery into coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7925y00 | connection of mammary artery to coronary artery os | res30: Ischaemic heart disease | diagnostic | Read |
| 7925z00 | connection of mammary artery to coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7926 | connection of other thoracic artery to coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7926000 | double anastom thoracic arteries to coronary arteries nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7926200 | single anastomosis of thoracic artery to coronary artery nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7926300 | single implantation thoracic artery into coronary artery nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7926z00 | connection of other thoracic artery to coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7927500 | open angioplasty of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7928 | transluminal balloon angioplasty of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7928.11 | percutaneous balloon coronary angioplasty | res30: Ischaemic heart disease | diagnostic | Read |
| 7928000 | percut transluminal balloon angioplasty one coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7928100 | percut translum balloon angioplasty mult coronary arteries | res30: Ischaemic heart disease | diagnostic | Read |
| 7928200 | percut translum balloon angioplasty bypass graft coronary a | res30: Ischaemic heart disease | diagnostic | Read |
| 7928300 | percut translum cutting balloon angioplasty coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7928y00 | transluminal balloon angioplasty of coronary artery os | res30: Ischaemic heart disease | diagnostic | Read |
| 7928z00 | transluminal balloon angioplasty of coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7929000 | percutaneous transluminal laser coronary angioplasty | res30: Ischaemic heart disease | diagnostic | Read |
| 7929100 | percut transluminal coronary thrombolysis with streptokinase | res30: Ischaemic heart disease | diagnostic | Read |
| 7929111 | percut translum coronary thrombolytic therapy- streptokinase | res30: Ischaemic heart disease | diagnostic | Read |
| 7929300 | rotary blade coronary angioplasty | res30: Ischaemic heart disease | diagnostic | Read |
| 7929400 | insertion of coronary artery stent | res30: Ischaemic heart disease | diagnostic | Read |
| 7929500 | insertion of drug-eluting coronary artery stent | res30: Ischaemic heart disease | diagnostic | Read |
| 7929600 | percutaneous transluminal atherectomy of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 792B000 | endarterectomy of coronary artery nec | res30: Ischaemic heart disease | diagnostic | Read |
| 792C.00 | other replacement of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 792C000 | replacement of coronary arteries using multiple methods | res30: Ischaemic heart disease | diagnostic | Read |
| 792Cy00 | other specified replacement of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 792Cz00 | replacement of coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 792D.00 | other bypass of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 792Dy00 | other specified other bypass of coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 792Dz00 | other bypass of coronary artery nos | res30: Ischaemic heart disease | diagnostic | Read |
| 793G.00 | perc translumin balloon angioplasty stenting coronary artery | res30: Ischaemic heart disease | diagnostic | Read |
| 793G000 | perc translum ball angio insert 1-2 drug elut stents cor art | res30: Ischaemic heart disease | diagnostic | Read |
| 793G100 | perc tran ball angio ins 3 or more drug elut stents cor art | res30: Ischaemic heart disease | diagnostic | Read |
| 793G200 | perc translum balloon angioplasty insert 1-2 stents cor art | res30: Ischaemic heart disease | diagnostic | Read |
| 793G300 | percutaneous cor balloon angiop 3 more stents cor art nec | res30: Ischaemic heart disease | diagnostic | Read |
| 793Gy00 | os perc translumina balloon angioplast stenting coronary art | res30: Ischaemic heart disease | diagnostic | Read |
| 793Gz00 | perc translum balloon angioplasty stenting coronary art nos | res30: Ischaemic heart disease | diagnostic | Read |
| 7A4B800 | percut translum thrombolysis femoral graft streptokinase | res30: Ischaemic heart disease | diagnostic | Read |
| 7A54000 | percutaneous transluminal angioplasty of artery nec | res30: Ischaemic heart disease | diagnostic | Read |
| 7A54500 | rotary blade angioplasty | res30: Ischaemic heart disease | diagnostic | Read |
| 7A54700 | percutaneous transluminal thrombolysis of artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7A54800 | percutaneous transluminal atherectomy | res30: Ischaemic heart disease | diagnostic | Read |
| 7A56000 | percutaneous transluminal arterial thrombolysis reconstruct | res30: Ischaemic heart disease | diagnostic | Read |
| 7A56400 | percutaneous transluminal balloon angioplasty of artery | res30: Ischaemic heart disease | diagnostic | Read |
| 7A6G100 | peroperative angioplasty | res30: Ischaemic heart disease | diagnostic | Read |
| 7A6H300 | prosthetic graft patch angioplasty | res30: Ischaemic heart disease | diagnostic | Read |
| 7A6H400 | percutaneous transluminal angioplasty of vascular graft | res30: Ischaemic heart disease | diagnostic | Read |
| 7A6S300 | percutaneous transluminal venous thrombolysis nec | res30: Ischaemic heart disease | diagnostic | Read |
| 889A.00 | diab mellit insulin-glucose infus acute myocardial infarct | res30: Ischaemic heart disease | diagnostic | Read |
| 8B27.00 | antianginal therapy | res30: Ischaemic heart disease | diagnostic | Read |
| 8B3k.00 | coronary heart disease medication review | res30: Ischaemic heart disease | diagnostic | Read |
| 8BGC.00 | long term dual antiplatelet drug therapy indicated | res30: Ischaemic heart disease | diagnostic | Read |
| 8CMP.00 | coronary heart disease care plan | res30: Ischaemic heart disease | diagnostic | Read |
| 8F9..00 | Cardiac rehabilitation | res30: Ischaemic heart disease | diagnostic | Read |
| 8F90.00 | Cardiac rehabilitation - phase 1 | res30: Ischaemic heart disease | diagnostic | Read |
| 8F91.00 | Cardiac rehabilitation - phase 2 | res30: Ischaemic heart disease | diagnostic | Read |
| 8F92.00 | Cardiac rehabilitation - phase 3 | res30: Ischaemic heart disease | diagnostic | Read |
| 8F93.00 | Cardiac rehabilitation - phase 4 | res30: Ischaemic heart disease | diagnostic | Read |
| 8H2V.00 | admit ischaemic heart disease emergency | res30: Ischaemic heart disease | diagnostic | Read |
| 8H7v.00 | Referral to cardiac rehabilitation nurse | res30: Ischaemic heart disease | diagnostic | Read |
| 8I37.00 | Coronary heart disease monitoring refused | res30: Ischaemic heart disease | diagnostic | Read |
| 8I3a.00 | Cardiac rehabilitation declined | res30: Ischaemic heart disease | diagnostic | Read |
| 8IEY.00 | referral to angina plan self-management programme declined | res30: Ischaemic heart disease | diagnostic | Read |
| 8L40.00 | coronary artery bypass graft operation planned | res30: Ischaemic heart disease | diagnostic | Read |
| 8L41.00 | coronary angioplasty planned | res30: Ischaemic heart disease | diagnostic | Read |
| 8LF..00 | coronary angiography planned | res30: Ischaemic heart disease | diagnostic | Read |
| 8T04.00 | referral to angina plan self-management programme | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob..00 | Coronary heart disease monitoring administration | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob0.00 | Attends coronary heart disease monitoring | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob1.00 | Refuses coronary heart disease monitoring | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob2.00 | Coronary heart disease monitoring default | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob3.00 | Coronary heart disease monitoring 1st letter | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob4.00 | Coronary heart disease monitoring 2nd letter | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob5.00 | Coronary heart disease monitoring 3rd letter | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob6.00 | Coronary heart disease monitoring verbal invitation | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob8.00 | Coronary heart disease monitoring check done | res30: Ischaemic heart disease | diagnostic | Read |
| 9Ob9.00 | Coronary heart disease monitoring telephone invite | res30: Ischaemic heart disease | diagnostic | Read |
| G....12 | Cardiac diseases | res30: Ischaemic heart disease | diagnostic | Read |
| G....13 | Heart diseases | res30: Ischaemic heart disease | diagnostic | Read |
| G3...00 | ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G3...11 | arteriosclerotic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G3...12 | atherosclerotic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G3...13 | ihd - ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G30..00 | acute myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30..11 | attack - heart | res30: Ischaemic heart disease | diagnostic | Read |
| G30..12 | coronary thrombosis | res30: Ischaemic heart disease | diagnostic | Read |
| G30..13 | cardiac rupture following myocardial infarction (mi) | res30: Ischaemic heart disease | diagnostic | Read |
| G30..14 | heart attack | res30: Ischaemic heart disease | diagnostic | Read |
| G30..15 | mi - acute myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30..16 | thrombosis - coronary | res30: Ischaemic heart disease | diagnostic | Read |
| G30..17 | silent myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G300.00 | acute anterolateral infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G301.00 | other specified anterior myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G301000 | acute anteroapical infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G301100 | acute anteroseptal infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G301z00 | anterior myocardial infarction nos | res30: Ischaemic heart disease | diagnostic | Read |
| G302.00 | acute inferolateral infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G303.00 | acute inferoposterior infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G304.00 | posterior myocardial infarction nos | res30: Ischaemic heart disease | diagnostic | Read |
| G305.00 | lateral myocardial infarction nos | res30: Ischaemic heart disease | diagnostic | Read |
| G306.00 | true posterior myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G307.00 | acute subendocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G307000 | acute non-q wave infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G307100 | acute non-st segment elevation myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G308.00 | inferior myocardial infarction nos | res30: Ischaemic heart disease | diagnostic | Read |
| G309.00 | acute q-wave infarct | res30: Ischaemic heart disease | diagnostic | Read |
| G30A.00 | mural thrombosis | res30: Ischaemic heart disease | diagnostic | Read |
| G30B.00 | acute posterolateral myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30X.00 | acute transmural myocardial infarction of unspecif site | res30: Ischaemic heart disease | diagnostic | Read |
| G30X000 | acute st segment elevation myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30y.00 | other acute myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30y000 | acute atrial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30y100 | acute papillary muscle infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30y200 | acute septal infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G30yz00 | other acute myocardial infarction nos | res30: Ischaemic heart disease | diagnostic | Read |
| G30z.00 | acute myocardial infarction nos | res30: Ischaemic heart disease | diagnostic | Read |
| G31..00 | other acute and subacute ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G310.00 | postmyocardial infarction syndrome | res30: Ischaemic heart disease | diagnostic | Read |
| G310.11 | dressler's syndrome | res30: Ischaemic heart disease | diagnostic | Read |
| G311.00 | preinfarction syndrome | res30: Ischaemic heart disease | diagnostic | Read |
| G311.11 | crescendo angina | res30: Ischaemic heart disease | diagnostic | Read |
| G311.12 | impending infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G311.13 | unstable angina | res30: Ischaemic heart disease | diagnostic | Read |
| G311.14 | angina at rest | res30: Ischaemic heart disease | diagnostic | Read |
| G311000 | myocardial infarction aborted | res30: Ischaemic heart disease | diagnostic | Read |
| G311011 | mi - myocardial infarction aborted | res30: Ischaemic heart disease | diagnostic | Read |
| G311100 | unstable angina | res30: Ischaemic heart disease | diagnostic | Read |
| G311200 | angina at rest | res30: Ischaemic heart disease | diagnostic | Read |
| G311300 | refractory angina | res30: Ischaemic heart disease | diagnostic | Read |
| G311400 | worsening angina | res30: Ischaemic heart disease | diagnostic | Read |
| G311500 | acute coronary syndrome | res30: Ischaemic heart disease | diagnostic | Read |
| G311z00 | preinfarction syndrome nos | res30: Ischaemic heart disease | diagnostic | Read |
| G312.00 | coronary thrombosis not resulting in myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G31y.00 | other acute and subacute ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G31y000 | acute coronary insufficiency | res30: Ischaemic heart disease | diagnostic | Read |
| G31y100 | microinfarction of heart | res30: Ischaemic heart disease | diagnostic | Read |
| G31y200 | subendocardial ischaemia | res30: Ischaemic heart disease | diagnostic | Read |
| G31y300 | transient myocardial ischaemia | res30: Ischaemic heart disease | diagnostic | Read |
| G31yz00 | other acute and subacute ischaemic heart disease nos | res30: Ischaemic heart disease | diagnostic | Read |
| G32..00 | old myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G32..11 | healed myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G32..12 | personal history of myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G33..00 | angina pectoris | res30: Ischaemic heart disease | diagnostic | Read |
| G330.00 | angina decubitus | res30: Ischaemic heart disease | diagnostic | Read |
| G330000 | nocturnal angina | res30: Ischaemic heart disease | diagnostic | Read |
| G330z00 | angina decubitus nos | res30: Ischaemic heart disease | diagnostic | Read |
| G331.11 | variant angina pectoris | res30: Ischaemic heart disease | diagnostic | Read |
| G332.00 | coronary artery spasm | res30: Ischaemic heart disease | diagnostic | Read |
| G33z.00 | angina pectoris nos | res30: Ischaemic heart disease | diagnostic | Read |
| G33z000 | status anginosus | res30: Ischaemic heart disease | diagnostic | Read |
| G33z100 | stenocardia | res30: Ischaemic heart disease | diagnostic | Read |
| G33z200 | syncope anginosa | res30: Ischaemic heart disease | diagnostic | Read |
| G33z300 | angina on effort | res30: Ischaemic heart disease | diagnostic | Read |
| G33z400 | ischaemic chest pain | res30: Ischaemic heart disease | diagnostic | Read |
| G33z500 | post infarct angina | res30: Ischaemic heart disease | diagnostic | Read |
| G33z600 | new onset angina | res30: Ischaemic heart disease | diagnostic | Read |
| G33z700 | stable angina | res30: Ischaemic heart disease | diagnostic | Read |
| G33zz00 | angina pectoris nos | res30: Ischaemic heart disease | diagnostic | Read |
| G34..00 | other chronic ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G340.00 | coronary atherosclerosis | res30: Ischaemic heart disease | diagnostic | Read |
| G340.11 | triple vessel disease of the heart | res30: Ischaemic heart disease | diagnostic | Read |
| G340.12 | coronary artery disease | res30: Ischaemic heart disease | diagnostic | Read |
| G340000 | single coronary vessel disease | res30: Ischaemic heart disease | diagnostic | Read |
| G340100 | double coronary vessel disease | res30: Ischaemic heart disease | diagnostic | Read |
| G341.00 | Aneurysm of heart | res30: Ischaemic heart disease | diagnostic | Read |
| G341.11 | Cardiac aneurysm | res30: Ischaemic heart disease | diagnostic | Read |
| G341000 | Ventricular cardiac aneurysm | res30: Ischaemic heart disease | diagnostic | Read |
| G341100 | Other cardiac wall aneurysm | res30: Ischaemic heart disease | diagnostic | Read |
| G341z00 | Aneurysm of heart NOS | res30: Ischaemic heart disease | diagnostic | Read |
| G342.00 | atherosclerotic cardiovascular disease | res30: Ischaemic heart disease | diagnostic | Read |
| G343.00 | Ischaemic cardiomyopathy | res30: Ischaemic heart disease | diagnostic | Read |
| G344.00 | silent myocardial ischaemia | res30: Ischaemic heart disease | diagnostic | Read |
| G34y.00 | other specified chronic ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G34y000 | chronic coronary insufficiency | res30: Ischaemic heart disease | diagnostic | Read |
| G34y100 | chronic myocardial ischaemia | res30: Ischaemic heart disease | diagnostic | Read |
| G34yz00 | other specified chronic ischaemic heart disease nos | res30: Ischaemic heart disease | diagnostic | Read |
| G34z.00 | other chronic ischaemic heart disease nos | res30: Ischaemic heart disease | diagnostic | Read |
| G34z000 | asymptomatic coronary heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G35..00 | subsequent myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G350.00 | subsequent myocardial infarction of anterior wall | res30: Ischaemic heart disease | diagnostic | Read |
| G351.00 | subsequent myocardial infarction of inferior wall | res30: Ischaemic heart disease | diagnostic | Read |
| G353.00 | subsequent myocardial infarction of other sites | res30: Ischaemic heart disease | diagnostic | Read |
| G35X.00 | subsequent myocardial infarction of unspecified site | res30: Ischaemic heart disease | diagnostic | Read |
| G36..00 | certain current complication follow acute myocardial infarct | res30: Ischaemic heart disease | diagnostic | Read |
| G360.00 | haemopericardium/current comp folow acut myocard infarct | res30: Ischaemic heart disease | diagnostic | Read |
| G361.00 | atrial septal defect/curr comp folow acut myocardal infarct | res30: Ischaemic heart disease | diagnostic | Read |
| G362.00 | ventric septal defect/curr comp fol acut myocardal infarctn | res30: Ischaemic heart disease | diagnostic | Read |
| G363.00 | ruptur cardiac wall w'out haemopericard/cur comp fol ac mi | res30: Ischaemic heart disease | diagnostic | Read |
| G364.00 | ruptur chordae tendinae/curr comp fol acute myocard infarct | res30: Ischaemic heart disease | diagnostic | Read |
| G365.00 | rupture papillary muscle/curr comp fol acute myocard infarct | res30: Ischaemic heart disease | diagnostic | Read |
| G366.00 | thrombosis atrium,auric append&vent/curr comp foll acute mi | res30: Ischaemic heart disease | diagnostic | Read |
| G38..00 | postoperative myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G380.00 | postoperative transmural myocardial infarction anterior wall | res30: Ischaemic heart disease | diagnostic | Read |
| G381.00 | postoperative transmural myocardial infarction inferior wall | res30: Ischaemic heart disease | diagnostic | Read |
| G383.00 | postoperative transmural myocardial infarction unspec site | res30: Ischaemic heart disease | diagnostic | Read |
| G384.00 | postoperative subendocardial myocardial infarction | res30: Ischaemic heart disease | diagnostic | Read |
| G38z.00 | postoperative myocardial infarction, unspecified | res30: Ischaemic heart disease | diagnostic | Read |
| G39..00 | coronary microvascular disease | res30: Ischaemic heart disease | diagnostic | Read |
| G3y..00 | other specified ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G3z..00 | ischaemic heart disease nos | res30: Ischaemic heart disease | diagnostic | Read |
| G5...00 | other forms of heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G501.00 | post infarction pericarditis | res30: Ischaemic heart disease | diagnostic | Read |
| G574000 | Ventricular fibrillation | res30: Ischaemic heart disease | diagnostic | Read |
| G5y..00 | other specified heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| G5yyz00 | Other ill-defined heart disease NOS | res30: Ischaemic heart disease | diagnostic | Read |
| G5yz.00 | other heart disease nos | res30: Ischaemic heart disease | diagnostic | Read |
| G5z..00 | heart disease nos | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu3.00 | [x]ischaemic heart diseases | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu3000 | [x]other forms of angina pectoris | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu3200 | [x]other forms of acute ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu3300 | [x]other forms of chronic ischaemic heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu3400 | [x]acute transmural myocardial infarction of unspecif site | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu3600 | [x]subsequent myocardial infarction of unspecified site | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu5.00 | [x]other forms of heart disease | res30: Ischaemic heart disease | diagnostic | Read |
| Gyu7000 | [x]atherosclerosis of other arteries | res30: Ischaemic heart disease | diagnostic | Read |
| SP00300 | mechanical complication of coronary bypass | res30: Ischaemic heart disease | diagnostic | Read |
| SP07600 | coronary artery bypass graft occlusion | res30: Ischaemic heart disease | diagnostic | Read |
| Z677.00 | Cardiac rehabilitation class | res30: Ischaemic heart disease | diagnostic | Read |
| ZL22200 | Under care of cardiac rehabilitation nurse | res30: Ischaemic heart disease | diagnostic | Read |
| ZV45700 | [v]presence of aortocoronary bypass graft | res30: Ischaemic heart disease | diagnostic | Read |
| ZV45800 | [v]presence of coronary angioplasty implant and graft | res30: Ischaemic heart disease | diagnostic | Read |
| ZV45K00 | [v]presence of coronary artery bypass graft | res30: Ischaemic heart disease | diagnostic | Read |
| ZV45K11 | [v]presence of coronary artery bypass graft - cabg | res30: Ischaemic heart disease | diagnostic | Read |
| ZV45L00 | [v]status following coronary angioplasty nos | res30: Ischaemic heart disease | diagnostic | Read |
| ZV57900 | [V]Cardiac rehabilitation | res30: Ischaemic heart disease | diagnostic | Read |
| Code | Description | Entity type | Category | Coding System (ICD-10 Read) |
|---|---|---|---|---|
| I20 | angina pectoris | res30: Ischaemic heart disease | diagnostic | ICD-10 |
| I20.0 | unstable angina |