Study population:
The study population included patients with a first diagnosis of psoriasis between January 1, 1994 and December 31, 2009, who were 20 years or older at the time of the diagnosis. A comparison group of up to 5 controls per psoriasis patient was selected. Patients from both cohorts did not have any history of CVD or diabetes before index date (first diagnosis of psoriasis) or corresponding consulting date and, in order to capture incident not prevalent cases of psoriasis or MI, all patients had to have at least 2 years prior registration within their general practice before entry into the study cohort. The control group consisted of patients who never received a diagnostic code for psoriasis. Controls were matched to psoriasis patients by age, gender, general practice and then by calendar time (date of first diagnosis of psoriasis). Person-time under observation for each patient was calculated from the corresponding index date up to end of the study which was the earliest date of the occurrence of the MI event, transfer out of the practice or death date, end of follow-up (December 31, 2011) or if the practice was no longer up to research data quality standards set by CPRD.
Definition of exposure:
Patients with psoriasis were included if they had their first diagnostic code for psoriasis during January 1, 1994-December 31, 2009 and received a recognised treatment for psoriasis (emollients, topical treatment, phototherapy, systemic therapy or biologics (CG153 Psoriasis: NICE guideline) (Samarasekera and Smith, 2014)). Patients were classified as having severe psoriasis once they had received a systemic treatment (acitretin, etretinate, ciclosporin, hydroxycarbamide, methotrexate, fumaric acid), phototherapy or a biologic therapy (etanercept, adalimumab, infliximab, ustekinumab, efalizumab); alternatively they were classified as mild psoriasis.
Outcome of interest:
The outcome of interest was fatal and non-fatal incident MI events. In our main analysis, MI events were identified using Read codes in CPRD. In sensitivity analysis, we identified MI events recorded in both CPRD and national mortality records (ONS) for those patients registered in practices that provided linked data between CPRD and ONS.
Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah PM Symmons, Christopher EM Griffiths, Darren M. Ashcroft, Psoriasis and the risk of myocardial infarction Cohort study using the clinical practive research datalink. 2014.
Code | Description | Entity type | Category | Coding System (Read) |
---|---|---|---|---|
323..00 | ECG: myocardial infarction | myocardial infarction - read | diagnostic | Read |
323Z.00 | ECG: myocardial infarct NOS | myocardial infarction - read | diagnostic | Read |
G30..00 | Acute myocardial infarction | myocardial infarction - read | diagnostic | Read |
G30..12 | Coronary thrombosis | myocardial infarction - read | diagnostic | Read |
G30..13 | Cardiac rupture following myocardial infarction (MI) | myocardial infarction - read | diagnostic | Read |
G30..15 | MI - acute myocardial infarction | myocardial infarction - read | diagnostic | Read |
G30..16 | Thrombosis - coronary | myocardial infarction - read | diagnostic | Read |
G30..17 | Silent myocardial infarction | myocardial infarction - read | diagnostic | Read |
G300.00 | Acute anterolateral infarction | myocardial infarction - read | diagnostic | Read |
G301.00 | Other specified anterior myocardial infarction | myocardial infarction - read | diagnostic | Read |
G301000 | Acute anteroapical infarction | myocardial infarction - read | diagnostic | Read |
G301100 | Acute anteroseptal infarction | myocardial infarction - read | diagnostic | Read |
G301z00 | Anterior myocardial infarction NOS | myocardial infarction - read | diagnostic | Read |
G302.00 | Acute inferolateral infarction | myocardial infarction - read | diagnostic | Read |
G303.00 | Acute inferoposterior infarction | myocardial infarction - read | diagnostic | Read |
G304.00 | Posterior myocardial infarction NOS | myocardial infarction - read | diagnostic | Read |
G305.00 | Lateral myocardial infarction NOS | myocardial infarction - read | diagnostic | Read |
G306.00 | True posterior myocardial infarction | myocardial infarction - read | diagnostic | Read |
G307.00 | Acute subendocardial infarction | myocardial infarction - read | diagnostic | Read |
G307000 | Acute non-Q wave infarction | myocardial infarction - read | diagnostic | Read |
G307100 | Acute non-ST segment elevation myocardial infarction | myocardial infarction - read | diagnostic | Read |
G308.00 | Inferior myocardial infarction NOS | myocardial infarction - read | diagnostic | Read |
G309.00 | Acute Q-wave infarct | myocardial infarction - read | diagnostic | Read |
G30B.00 | Acute posterolateral myocardial infarction | myocardial infarction - read | diagnostic | Read |
G30X.00 | Acute transmural myocardial infarction of unspecif site | myocardial infarction - read | diagnostic | Read |
G30X000 | Acute ST segment elevation myocardial infarction | myocardial infarction - read | diagnostic | Read |
G30y.00 | Other acute myocardial infarction | myocardial infarction - read | diagnostic | Read |
G30y100 | Acute papillary muscle infarction | myocardial infarction - read | diagnostic | Read |
G30y200 | Acute septal infarction | myocardial infarction - read | diagnostic | Read |
G30yz00 | Other acute myocardial infarction NOS | myocardial infarction - read | diagnostic | Read |
G30z.00 | Acute myocardial infarction NOS | myocardial infarction - read | diagnostic | Read |
G311000 | Myocardial infarction aborted | myocardial infarction - read | diagnostic | Read |
G311011 | MI - myocardial infarction aborted | myocardial infarction - read | diagnostic | Read |
G311500 | Acute coronary syndrome | myocardial infarction - read | diagnostic | Read |
G35..00 | Subsequent myocardial infarction | myocardial infarction - read | diagnostic | Read |
G350.00 | Subsequent myocardial infarction of anterior wall | myocardial infarction - read | diagnostic | Read |
G351.00 | Subsequent myocardial infarction of inferior wall | myocardial infarction - read | diagnostic | Read |
G353.00 | Subsequent myocardial infarction of other sites | myocardial infarction - read | diagnostic | Read |
G35X.00 | Subsequent myocardial infarction of unspecified site | myocardial infarction - read | diagnostic | Read |
G360.00 | Haemopericardium/current comp folow acut myocard infarct | myocardial infarction - read | diagnostic | Read |
G362.00 | Ventric septal defect/curr comp fol acut myocardal infarctn | myocardial infarction - read | diagnostic | Read |
G363.00 | Ruptur cardiac wall w'out haemopericard/cur comp fol ac MI | myocardial infarction - read | diagnostic | Read |
G364.00 | Ruptur chordae tendinae/curr comp fol acute myocard infarct | myocardial infarction - read | diagnostic | Read |
G365.00 | Rupture papillary muscle/curr comp fol acute myocard infarct | myocardial infarction - read | diagnostic | Read |
G38..00 | Postoperative myocardial infarction | myocardial infarction - read | diagnostic | Read |
G380.00 | Postoperative transmural myocardial infarction anterior wall | myocardial infarction - read | diagnostic | Read |
G381.00 | Postoperative transmural myocardial infarction inferior wall | myocardial infarction - read | diagnostic | Read |
G384.00 | Postoperative subendocardial myocardial infarction | myocardial infarction - read | diagnostic | Read |
G38z.00 | Postoperative myocardial infarction, unspecified | myocardial infarction - read | diagnostic | Read |
G574011 | Cardiac arrest-ventricular fibrillation | myocardial infarction - read | diagnostic | Read |
G575.00 | Cardiac arrest | myocardial infarction - read | diagnostic | Read |
G575.11 | Cardio-respiratory arrest | myocardial infarction - read | diagnostic | Read |
G575.12 | Asystole | myocardial infarction - read | diagnostic | Read |
G575000 | Cardiac arrest with successful resuscitation | myocardial infarction - read | diagnostic | Read |
G575100 | Sudden cardiac death, so described | myocardial infarction - read | diagnostic | Read |
G575z00 | Cardiac arrest, unspecified | myocardial infarction - read | diagnostic | Read |
Gyu3400 | [X]Acute transmural myocardial infarction of unspecif site | myocardial infarction - read | diagnostic | Read |
Gyu3600 | [X]Subsequent myocardial infarction of unspecified site | myocardial infarction - read | diagnostic | Read |
To Export Phenotype Details:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH613/version/1226/detail/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH613/version/1226/detail/?format=json |
R Package |
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To Export Phenotype Code List:
Format | API |
---|---|
XML | site_root/api/v1/public/phenotypes/PH613/version/1226/export/codes/?format=xml |
JSON | site_root/api/v1/public/phenotypes/PH613/version/1226/export/codes/?format=json |
CSV | site_root/phenotypes/PH613/version/1226/export/codes/ |
R Package |
|
Version ID |
Name | Owner | Publish date | |
---|---|---|---|---|
1226 | Myocardial Infarction | ieuan.scanlon | 2021-10-06 | currently shown |
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