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Myocardial Infarction

Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah PM Symmons, Christopher EM Griffiths, Darren M Ashcroft

ID
PH613
Version ID
1226
Type
Disease or Syndrome
Data Sources
Valid event data range
01/01/1994 - 31/12/2009
Sex
♀  Female ♂  Male
Agreement Date
2014-12-31
Coding system
Read codes v2
Collections
ClinicalCodes Repository Phenotype Library
Tags
No tags

Definition

Study population:

The study population included patients with a first diagnosis of psoriasis between January 1, 1994 and December 31, 2009, who were 20 years or older at the time of the diagnosis. A comparison group of up to 5 controls per psoriasis patient was selected. Patients from both cohorts did not have any history of CVD or diabetes before index date (first diagnosis of psoriasis) or corresponding consulting date and, in order to capture incident not prevalent cases of psoriasis or MI, all patients had to have at least 2 years prior registration within their general practice before entry into the study cohort. The control group consisted of patients who never received a diagnostic code for psoriasis. Controls were matched to psoriasis patients by age, gender, general practice and then by calendar time (date of first diagnosis of psoriasis). Person-time under observation for each patient was calculated from the corresponding index date up to end of the study which was the earliest date of the occurrence of the MI event, transfer out of the practice or death date, end of follow-up (December 31, 2011) or if the practice was no longer up to research data quality standards set by CPRD.

Definition of exposure:

Patients with psoriasis were included if they had their first diagnostic code for psoriasis during January 1, 1994-December 31, 2009 and received a recognised treatment for psoriasis (emollients, topical treatment, phototherapy, systemic therapy or biologics (CG153 Psoriasis: NICE guideline) (Samarasekera and Smith, 2014)). Patients were classified as having severe psoriasis once they had received a systemic treatment (acitretin, etretinate, ciclosporin, hydroxycarbamide, methotrexate, fumaric acid), phototherapy or a biologic therapy (etanercept, adalimumab, infliximab, ustekinumab, efalizumab); alternatively they were classified as mild psoriasis.

Outcome of interest:

The outcome of interest was fatal and non-fatal incident MI events. In our main analysis, MI events were identified using Read codes in CPRD. In sensitivity analysis, we identified MI events recorded in both CPRD and national mortality records (ONS) for those patients registered in practices that provided linked data between CPRD and ONS.

Publications

  • Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah PM Symmons, Christopher EM Griffiths, Darren M. Ashcroft, Psoriasis and the risk of myocardial infarction Cohort study using the clinical practive research datalink. 2014.

Clinical Code List

Rows: 58
Code Description Entity type Category Coding System (Read)
323..00 ECG: myocardial infarction myocardial infarction - read diagnostic Read
323Z.00 ECG: myocardial infarct NOS myocardial infarction - read diagnostic Read
G30..00 Acute myocardial infarction myocardial infarction - read diagnostic Read
G30..12 Coronary thrombosis myocardial infarction - read diagnostic Read
G30..13 Cardiac rupture following myocardial infarction (MI) myocardial infarction - read diagnostic Read
G30..15 MI - acute myocardial infarction myocardial infarction - read diagnostic Read
G30..16 Thrombosis - coronary myocardial infarction - read diagnostic Read
G30..17 Silent myocardial infarction myocardial infarction - read diagnostic Read
G300.00 Acute anterolateral infarction myocardial infarction - read diagnostic Read
G301.00 Other specified anterior myocardial infarction myocardial infarction - read diagnostic Read
G301000 Acute anteroapical infarction myocardial infarction - read diagnostic Read
G301100 Acute anteroseptal infarction myocardial infarction - read diagnostic Read
G301z00 Anterior myocardial infarction NOS myocardial infarction - read diagnostic Read
G302.00 Acute inferolateral infarction myocardial infarction - read diagnostic Read
G303.00 Acute inferoposterior infarction myocardial infarction - read diagnostic Read
G304.00 Posterior myocardial infarction NOS myocardial infarction - read diagnostic Read
G305.00 Lateral myocardial infarction NOS myocardial infarction - read diagnostic Read
G306.00 True posterior myocardial infarction myocardial infarction - read diagnostic Read
G307.00 Acute subendocardial infarction myocardial infarction - read diagnostic Read
G307000 Acute non-Q wave infarction myocardial infarction - read diagnostic Read
G307100 Acute non-ST segment elevation myocardial infarction myocardial infarction - read diagnostic Read
G308.00 Inferior myocardial infarction NOS myocardial infarction - read diagnostic Read
G309.00 Acute Q-wave infarct myocardial infarction - read diagnostic Read
G30B.00 Acute posterolateral myocardial infarction myocardial infarction - read diagnostic Read
G30X.00 Acute transmural myocardial infarction of unspecif site myocardial infarction - read diagnostic Read
G30X000 Acute ST segment elevation myocardial infarction myocardial infarction - read diagnostic Read
G30y.00 Other acute myocardial infarction myocardial infarction - read diagnostic Read
G30y100 Acute papillary muscle infarction myocardial infarction - read diagnostic Read
G30y200 Acute septal infarction myocardial infarction - read diagnostic Read
G30yz00 Other acute myocardial infarction NOS myocardial infarction - read diagnostic Read
G30z.00 Acute myocardial infarction NOS myocardial infarction - read diagnostic Read
G311000 Myocardial infarction aborted myocardial infarction - read diagnostic Read
G311011 MI - myocardial infarction aborted myocardial infarction - read diagnostic Read
G311500 Acute coronary syndrome myocardial infarction - read diagnostic Read
G35..00 Subsequent myocardial infarction myocardial infarction - read diagnostic Read
G350.00 Subsequent myocardial infarction of anterior wall myocardial infarction - read diagnostic Read
G351.00 Subsequent myocardial infarction of inferior wall myocardial infarction - read diagnostic Read
G353.00 Subsequent myocardial infarction of other sites myocardial infarction - read diagnostic Read
G35X.00 Subsequent myocardial infarction of unspecified site myocardial infarction - read diagnostic Read
G360.00 Haemopericardium/current comp folow acut myocard infarct myocardial infarction - read diagnostic Read
G362.00 Ventric septal defect/curr comp fol acut myocardal infarctn myocardial infarction - read diagnostic Read
G363.00 Ruptur cardiac wall w'out haemopericard/cur comp fol ac MI myocardial infarction - read diagnostic Read
G364.00 Ruptur chordae tendinae/curr comp fol acute myocard infarct myocardial infarction - read diagnostic Read
G365.00 Rupture papillary muscle/curr comp fol acute myocard infarct myocardial infarction - read diagnostic Read
G38..00 Postoperative myocardial infarction myocardial infarction - read diagnostic Read
G380.00 Postoperative transmural myocardial infarction anterior wall myocardial infarction - read diagnostic Read
G381.00 Postoperative transmural myocardial infarction inferior wall myocardial infarction - read diagnostic Read
G384.00 Postoperative subendocardial myocardial infarction myocardial infarction - read diagnostic Read
G38z.00 Postoperative myocardial infarction, unspecified myocardial infarction - read diagnostic Read
G574011 Cardiac arrest-ventricular fibrillation myocardial infarction - read diagnostic Read
G575.00 Cardiac arrest myocardial infarction - read diagnostic Read
G575.11 Cardio-respiratory arrest myocardial infarction - read diagnostic Read
G575.12 Asystole myocardial infarction - read diagnostic Read
G575000 Cardiac arrest with successful resuscitation myocardial infarction - read diagnostic Read
G575100 Sudden cardiac death, so described myocardial infarction - read diagnostic Read
G575z00 Cardiac arrest, unspecified myocardial infarction - read diagnostic Read
Gyu3400 [X]Acute transmural myocardial infarction of unspecif site myocardial infarction - read diagnostic Read
Gyu3600 [X]Subsequent myocardial infarction of unspecified site myocardial infarction - read diagnostic Read

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH613/version/1226/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH613/version/1226/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH613', '1226', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH613/version/1226/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH613/version/1226/export/codes/?format=json
CSV site_root/phenotypes/PH613/version/1226/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH613', '1226', api_client=client)

Version History

Version
ID
Name Owner Publish date
1226 Myocardial Infarction ieuan.scanlon 2021-10-06 currently shown

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