Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah PM Symmons, Christopher EM Griffiths, Darren M Ashcroft

Version ID
Disease or Syndrome
Data Sources
Valid event data range
01/01/1994 - 31/12/2009
♀  Female ♂  Male
Agreement Date
Coding system
Read codes v2
ClinicalCodes Repository Phenotype Library
No tags


Study population:

The study population included patients with a first diagnosis of psoriasis between January 1, 1994 and December 31, 2009, who were 20 years or older at the time of the diagnosis. A comparison group of up to 5 controls per psoriasis patient was selected. Patients from both cohorts did not have any history of CVD or diabetes before index date (first diagnosis of psoriasis) or corresponding consulting date and, in order to capture incident not prevalent cases of psoriasis or MI, all patients had to have at least 2 years prior registration within their general practice before entry into the study cohort. The control group consisted of patients who never received a diagnostic code for psoriasis. Controls were matched to psoriasis patients by age, gender, general practice and then by calendar time (date of first diagnosis of psoriasis). Person-time under observation for each patient was calculated from the corresponding index date up to end of the study which was the earliest date of the occurrence of the MI event, transfer out of the practice or death date, end of follow-up (December 31, 2011) or if the practice was no longer up to research data quality standards set by CPRD.

Definition of exposure:

Patients with psoriasis were included if they had their first diagnostic code for psoriasis during January 1, 1994-December 31, 2009 and received a recognised treatment for psoriasis (emollients, topical treatment, phototherapy, systemic therapy or biologics (CG153 Psoriasis: NICE guideline) (Samarasekera and Smith, 2014)). Patients were classified as having severe psoriasis once they had received a systemic treatment (acitretin, etretinate, ciclosporin, hydroxycarbamide, methotrexate, fumaric acid), phototherapy or a biologic therapy (etanercept, adalimumab, infliximab, ustekinumab, efalizumab); alternatively they were classified as mild psoriasis.

Outcome of interest:

The outcome of interest was fatal and non-fatal incident MI events. In our main analysis, MI events were identified using Read codes in CPRD. In sensitivity analysis, we identified MI events recorded in both CPRD and national mortality records (ONS) for those patients registered in practices that provided linked data between CPRD and ONS.


  • Rosa Parisi, Martin K Rutter, Mark Lunt, Helen S Young, Deborah PM Symmons, Christopher EM Griffiths, Darren M. Ashcroft, Psoriasis and the risk of myocardial infarction Cohort study using the clinical practive research datalink. 2014.

Clinical Code List

Rows: 24
Code Description Entity type Category Coding System (Read)
M16..00 Psoriasis and similar disorders psoriasis diagnostic Read
M161.00 Other psoriasis psoriasis diagnostic Read
M161000 Psoriasis unspecified psoriasis diagnostic Read
M161100 Psoriasis annularis psoriasis diagnostic Read
M161200 Psoriasis circinata psoriasis diagnostic Read
M161300 Psoriasis diffusa psoriasis diagnostic Read
M161400 Psoriasis discoidea psoriasis diagnostic Read
M161500 Psoriasis geographica psoriasis diagnostic Read
M161600 Guttate psoriasis psoriasis diagnostic Read
M161700 Psoriasis gyrata psoriasis diagnostic Read
M161800 Psoriasis inveterata psoriasis diagnostic Read
M161900 Psoriasis ostracea psoriasis diagnostic Read
M161A00 Psoriasis palmaris psoriasis diagnostic Read
M161B00 Psoriasis plantaris psoriasis diagnostic Read
M161C00 Psoriasis punctata psoriasis diagnostic Read
M161E00 Psoriasis universalis psoriasis diagnostic Read
M161F00 Psoriasis vulgaris psoriasis diagnostic Read
M161F11 Chronic large plaque psoriasis psoriasis diagnostic Read
M161H00 Erythrodermic psoriasis psoriasis diagnostic Read
M161z00 Psoriasis NOS psoriasis diagnostic Read
M16y.00 Other psoriasis and similar disorders psoriasis diagnostic Read
M16y000 Scalp psoriasis psoriasis diagnostic Read
M16z.00 Psoriasis and similar disorders NOS psoriasis diagnostic Read
Myu3000 [X]Other psoriasis psoriasis diagnostic Read


To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH614/version/1228/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH614/version/1228/detail/?format=json
R Package

# Download here


# Connect to API

client = connect_to_API(public=TRUE)

# Get details of phenotype

details = get_phenotype_detail_by_version('PH614', '1228', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH614/version/1228/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH614/version/1228/export/codes/?format=json
CSV site_root/phenotypes/PH614/version/1228/export/codes/
R Package

# Download here


# Connect to API

client = connect_to_API(public=TRUE)

# Get codelists of phenotype

codelists = get_phenotype_code_list('PH614', '1228', api_client=client)

Version History

Name Owner Publish date
1228 Psoriasis ieuan.scanlon 2021-10-06 currently shown

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