Phenotype Library | phenotype: Motor neuron disease

Motor neuron disease

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A

PH62

Version ID

124

Type

Disease or Syndrome

Data Sources

CPRD GOLD , HES Admitted Patient Care data for CPRD GOLD

Valid event data range

01/01/1999 - 01/07/2016

Sex

♀ Female ♂ Male

Agreement Date

2019-05-20

Coding system

Read codes v2 ICD10 codes Med codes

Collections

CALIBER Phenotype Library

Definition

At the specified date, a patient is defined as having had motor neuron disease IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care

Motor neuron disease diagnosis or history of diagnosis during a consultation

OR Secondary care

ALL diagnoses of motor neuron disease or history of diagnosis during a hospitalization

Implementation

PhenoFlow Implementation:

https://kclhi.org/phenoflow/phenotype/download/182

Publications

Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3

Clinical Code List

CSV

JSON

XML

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C852/2843 Motor neuron disease - Primary care - Read codes v2

Rows: 12

Code	Description	Disease	Medcode	Category
7Q04100	Amyotrophic lateral sclerosis drugs Band 1	Motor neuron disease	109020.0	History of Motor neuron disease
F15..00	Anterior horn cell disease	Motor neuron disease	21889.0	Diagnosis of Motor neuron disease
F152.00	Motor neurone disease	Motor neuron disease	4796.0	Diagnosis of Motor neuron disease
F152000	Amyotrophic lateral sclerosis	Motor neuron disease	36433.0	Diagnosis of Motor neuron disease
F152100	Progressive muscular atrophy	Motor neuron disease	30987.0	Diagnosis of Motor neuron disease
F152111	Duchenne Aran muscular atrophy	Motor neuron disease	7470.0	Diagnosis of Motor neuron disease
F152200	Progressive bulbar palsy	Motor neuron disease	27377.0	Diagnosis of Motor neuron disease
F152300	Pseudobulbar palsy	Motor neuron disease	18084.0	Diagnosis of Motor neuron disease
F152400	Primary lateral sclerosis	Motor neuron disease	20845.0	Diagnosis of Motor neuron disease
F152z00	Motor neurone disease NOS	Motor neuron disease	20120.0	Diagnosis of Motor neuron disease
F15y.00	Other anterior horn cell disease	Motor neuron disease	71400.0	Diagnosis of Motor neuron disease
F15z.00	Anterior horn cell disease NOS	Motor neuron disease	58729.0	Diagnosis of Motor neuron disease

C853/2845 Motor neuron disease - Primary care - Med codes

Rows: 12

Code	Description	Disease	ReadcodeDescr	Readcode
109020.0	History of Motor neuron disease	Motor neuron disease	Amyotrophic lateral sclerosis drugs Band 1	7Q04100
18084.0	Diagnosis of Motor neuron disease	Motor neuron disease	Pseudobulbar palsy	F152300
20120.0	Diagnosis of Motor neuron disease	Motor neuron disease	Motor neurone disease NOS	F152z00
20845.0	Diagnosis of Motor neuron disease	Motor neuron disease	Primary lateral sclerosis	F152400
21889.0	Diagnosis of Motor neuron disease	Motor neuron disease	Anterior horn cell disease	F15..00
27377.0	Diagnosis of Motor neuron disease	Motor neuron disease	Progressive bulbar palsy	F152200
30987.0	Diagnosis of Motor neuron disease	Motor neuron disease	Progressive muscular atrophy	F152100
36433.0	Diagnosis of Motor neuron disease	Motor neuron disease	Amyotrophic lateral sclerosis	F152000
4796.0	Diagnosis of Motor neuron disease	Motor neuron disease	Motor neurone disease	F152.00
58729.0	Diagnosis of Motor neuron disease	Motor neuron disease	Anterior horn cell disease NOS	F15z.00
71400.0	Diagnosis of Motor neuron disease	Motor neuron disease	Other anterior horn cell disease	F15y.00
7470.0	Diagnosis of Motor neuron disease	Motor neuron disease	Duchenne Aran muscular atrophy	F152111

C854/2847 Motor neuron disease - Secondary care - Diagnoses - ICD10 codes

Rows: 1

Code	Description	Disease	Category
G12.2	Motor neuron disease	Motor neuron disease	Diagnosis of Motor neuron disease

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH62/version/124/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH62/version/124/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH62', '124', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH62/version/124/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH62/version/124/export/codes/?format=json
CSV	site_root/phenotypes/PH62/version/124/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH62', '124', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
124	Motor neuron disease	ieuan.scanlon	2021-10-06	currently shown