Phenotype Library | phenotype: Dementia

Dementia

Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis

PH628

Version ID

1256

Type

Disease or Syndrome

Data Sources

CPRD GOLD

Valid event data range

01/04/2000 - 31/03/2012

Sex

♂ Male

Agreement Date

2015-12-15

Coding system

Read codes v2 OXMIS codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

Objectives:

Little is known about the prevalence of comorbidity rates in people with severe mental illness (SMI) in UK primary care. We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.

Design:

Retrospective cohort study from 2000 to 2012.

Setting:

627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.

Participants:

Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.

Outcome measures:

Prevalence rates were calculated for 16 conditions.

Publications

Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis, Inequalities in physical comorbidity a longitudinal comparative cohort study of people with severe mental illness in the UK. BMJ Open, 5(e009010), 2015.

Clinical Code List

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C2038/5214 Dementia - Primary Care - Read codes v2

Rows: 73

Code	Description	Entity type	Coding System (OXMIS Read)	Category
E00..00	Senile and presenile organic psychotic conditions	res26: Dementia	Read	diagnostic
E00..11	Senile dementia	res26: Dementia	Read	diagnostic
E00..12	Senile/presenile dementia	res26: Dementia	Read	diagnostic
E000.00	Uncomplicated senile dementia	res26: Dementia	Read	diagnostic
E001.00	Presenile dementia	res26: Dementia	Read	diagnostic
E001000	Uncomplicated presenile dementia	res26: Dementia	Read	diagnostic
E001100	Presenile dementia with delirium	res26: Dementia	Read	diagnostic
E001200	Presenile dementia with paranoia	res26: Dementia	Read	diagnostic
E001300	Presenile dementia with depression	res26: Dementia	Read	diagnostic
E001z00	Presenile dementia NOS	res26: Dementia	Read	diagnostic
E002.00	Senile dementia with depressive or paranoid features	res26: Dementia	Read	diagnostic
E002000	Senile dementia with paranoia	res26: Dementia	Read	diagnostic
E002100	Senile dementia with depression	res26: Dementia	Read	diagnostic
E002z00	Senile dementia with depressive or paranoid features NOS	res26: Dementia	Read	diagnostic
E003.00	Senile dementia with delirium	res26: Dementia	Read	diagnostic
E004.00	Arteriosclerotic dementia	res26: Dementia	Read	diagnostic
E004.11	Multi infarct dementia	res26: Dementia	Read	diagnostic
E004000	Uncomplicated arteriosclerotic dementia	res26: Dementia	Read	diagnostic
E004100	Arteriosclerotic dementia with delirium	res26: Dementia	Read	diagnostic
E004200	Arteriosclerotic dementia with paranoia	res26: Dementia	Read	diagnostic
E004300	Arteriosclerotic dementia with depression	res26: Dementia	Read	diagnostic
E004z00	Arteriosclerotic dementia NOS	res26: Dementia	Read	diagnostic
E00y.00	Other senile and presenile organic psychoses	res26: Dementia	Read	diagnostic
E00y.11	Presbyophrenic psychosis	res26: Dementia	Read	diagnostic
E00z.00	Senile or presenile psychoses NOS	res26: Dementia	Read	diagnostic
E012.00	Other alcoholic dementia	res26: Dementia	Read	diagnostic
E012.11	Alcoholic dementia NOS	res26: Dementia	Read	diagnostic
E012000	Chronic alcoholic brain syndrome	res26: Dementia	Read	diagnostic
E041.00	Dementia in conditions EC	res26: Dementia	Read	diagnostic
Eu00.00	[X]Dementia in Alzheimer's disease	res26: Dementia	Read	diagnostic
Eu00000	[X]Dementia in Alzheimer's disease with early onset	res26: Dementia	Read	diagnostic
Eu00011	[X]Presenile dementia,Alzheimer's type	res26: Dementia	Read	diagnostic
Eu00012	[X]Primary degen dementia, Alzheimer's type, presenile onset	res26: Dementia	Read	diagnostic
Eu00013	[X]Alzheimer's disease type 2	res26: Dementia	Read	diagnostic
Eu00100	[X]Dementia in Alzheimer's disease with late onset	res26: Dementia	Read	diagnostic
Eu00111	[X]Alzheimer's disease type 1	res26: Dementia	Read	diagnostic
Eu00112	[X]Senile dementia,Alzheimer's type	res26: Dementia	Read	diagnostic
Eu00113	[X]Primary degen dementia of Alzheimer's type, senile onset	res26: Dementia	Read	diagnostic
Eu00200	[X]Dementia in Alzheimer's dis, atypical or mixed type	res26: Dementia	Read	diagnostic
Eu00z00	[X]Dementia in Alzheimer's disease, unspecified	res26: Dementia	Read	diagnostic
Eu00z11	[X]Alzheimer's dementia unspec	res26: Dementia	Read	diagnostic
Eu01.00	[X]Vascular dementia	res26: Dementia	Read	diagnostic
Eu01.11	[X]Arteriosclerotic dementia	res26: Dementia	Read	diagnostic
Eu01000	[X]Vascular dementia of acute onset	res26: Dementia	Read	diagnostic
Eu01100	[X]Multi-infarct dementia	res26: Dementia	Read	diagnostic
Eu01111	[X]Predominantly cortical dementia	res26: Dementia	Read	diagnostic
Eu01200	[X]Subcortical vascular dementia	res26: Dementia	Read	diagnostic
Eu01300	[X]Mixed cortical and subcortical vascular dementia	res26: Dementia	Read	diagnostic
Eu01y00	[X]Other vascular dementia	res26: Dementia	Read	diagnostic
Eu01z00	[X]Vascular dementia, unspecified	res26: Dementia	Read	diagnostic
Eu02.00	[X]Dementia in other diseases classified elsewhere	res26: Dementia	Read	diagnostic
Eu02000	[X]Dementia in Pick's disease	res26: Dementia	Read	diagnostic
Eu02100	[X]Dementia in Creutzfeldt-Jakob disease	res26: Dementia	Read	diagnostic
Eu02200	[X]Dementia in Huntington's disease	res26: Dementia	Read	diagnostic
Eu02300	[X]Dementia in Parkinson's disease	res26: Dementia	Read	diagnostic
Eu02400	[X]Dementia in human immunodef virus [HIV] disease	res26: Dementia	Read	diagnostic
Eu02500	[X]Lewy body dementia	res26: Dementia	Read	diagnostic
Eu02y00	[X]Dementia in other specified diseases classif elsewhere	res26: Dementia	Read	diagnostic
Eu02z00	[X] Unspecified dementia	res26: Dementia	Read	diagnostic
Eu02z11	[X] Presenile dementia NOS	res26: Dementia	Read	diagnostic
Eu02z12	[X] Presenile psychosis NOS	res26: Dementia	Read	diagnostic
Eu02z13	[X] Primary degenerative dementia NOS	res26: Dementia	Read	diagnostic
Eu02z14	[X] Senile dementia NOS	res26: Dementia	Read	diagnostic
Eu02z15	[X] Senile psychosis NOS	res26: Dementia	Read	diagnostic
Eu02z16	[X] Senile dementia, depressed or paranoid type	res26: Dementia	Read	diagnostic
Eu10711	[X]Alcoholic dementia NOS	res26: Dementia	Read	diagnostic
F110.00	Alzheimer's disease	res26: Dementia	Read	diagnostic
F110000	Alzheimer's disease with early onset	res26: Dementia	Read	diagnostic
F110100	Alzheimer's disease with late onset	res26: Dementia	Read	diagnostic
F111.00	Pick's disease	res26: Dementia	Read	diagnostic
F112.00	Senile degeneration of brain	res26: Dementia	Read	diagnostic
F116.00	Lewy body disease	res26: Dementia	Read	diagnostic
Fyu3000	[X]Other Alzheimer's disease	res26: Dementia	Read	diagnostic

C2039/5216 Dementia - Primary Care - OXMIS codes

Rows: 8

Code	Description	Entity type	Coding System (OXMIS Read)	Category
2900	SENILE DEMENTIA	res26: Dementia	OXMIS	diagnostic
2901A	PRESENILE DEMENTIA	res26: Dementia	OXMIS	diagnostic
2901B	ALZHEIMER'S DISEASE	res26: Dementia	OXMIS	diagnostic
2901D	JACOB- CREUZFELDT DISEASE WITH DEMENTIA	res26: Dementia	OXMIS	diagnostic
2919	DEMENTIA ALCOHOLIC	res26: Dementia	OXMIS	diagnostic
2930	DEMENTIA ARTERIOSCLEROTIC	res26: Dementia	OXMIS	diagnostic
299 B	DEMENTIA	res26: Dementia	OXMIS	diagnostic
299 G	DEMENTIA AGGRESSIVE	res26: Dementia	OXMIS	diagnostic

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH628/version/1256/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH628/version/1256/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH628', '1256', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH628/version/1256/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH628/version/1256/export/codes/?format=json
CSV	site_root/phenotypes/PH628/version/1256/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH628', '1256', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
1256	Dementia	ieuan.scanlon	2021-10-06	currently shown