Phenotype Library | phenotype: Multiple sclerosis

Multiple sclerosis

Kuan V, Denaxas S, Gonzalez-Izquierdo A, Direk K, Bhatti O, Husain S, Sutaria S, Hingorani M, Nitsch D, Parisinos C, Lumbers T, Mathur R, Sofat R, Casas JP, Wong I, Hemingway H, Hingorani A

PH63

Version ID

126

Type

Disease or Syndrome

Data Sources

CPRD GOLD , HES Admitted Patient Care data for CPRD GOLD

Valid event data range

01/01/1999 - 01/07/2016

Sex

♀ Female ♂ Male

Agreement Date

2019-05-20

Coding system

Read codes v2 ICD10 codes Med codes

Collections

CALIBER Phenotype Library

Definition

At the specified date, a patient is defined as having had 'Multiple sclerosis' IF they meet the criteria for any of the following on or before the specified date. The earliest date on which the individual meets any of the following criteria on or before the specified date is defined as the first event date:

Primary care

'Multiple sclerosis' diagnosis or history of diagnosis during a consultation

OR Secondary care

ALL diagnoses of 'Multiple sclerosis' or history of diagnosis during a hospitalization

Implementation

PhenoFlow Implementation:

https://kclhi.org/phenoflow/phenotype/download/184

Publications

Kuan V., Denaxas S., Gonzalez-Izquierdo A. et al. A chronological map of 308 physical and mental health conditions from 4 million individuals in the National Health Service. The Lancet Digital Health - DOI 10.1016/S2589-7500(19)30012-3

Clinical Code List

CSV

JSON

XML

Expand All / Collapse All

C855/2849 Multiple sclerosis - Primary care - Read codes v2

Rows: 23

Code	Description	Disease	Medcode	Category
666A.00	Multiple sclerosis review	Multiple sclerosis	44985.0	History of Multiple sclerosis
666B.00	Multiple sclerosis multidisciplinary review	Multiple sclerosis	43232.0	History of Multiple sclerosis
8CS1.00	Multiple sclerosis care plan agreed	Multiple sclerosis	50161.0	History of Multiple sclerosis
8Cc0.00	Management of multiple sclerosis in onset phase	Multiple sclerosis	98835.0	Diagnosis of Multiple sclerosis
8Cc1.00	Management of multiple sclerosis in early disease phase	Multiple sclerosis	97487.0	Diagnosis of Multiple sclerosis
8Cc2.00	Management of multiple sclerosis in stable disability phase	Multiple sclerosis	95864.0	History of Multiple sclerosis
8Cc4.00	Management of multiple sclerosis in palliative phase	Multiple sclerosis	98521.0	History of Multiple sclerosis
8IAb.00	Multiple sclerosis review declined	Multiple sclerosis	100503.0	History of Multiple sclerosis
9kG..00	Spec serv for pat with multiple sclerosis - enh serv admin	Multiple sclerosis	48527.0	History of Multiple sclerosis
9mD..00	Multiple sclerosis monitoring administration	Multiple sclerosis	106307.0	History of Multiple sclerosis
9mD0.00	Multiple sclerosis monitoring first letter	Multiple sclerosis	109049.0	History of Multiple sclerosis
9mD1.00	Multiple sclerosis monitoring second letter	Multiple sclerosis	109302.0	History of Multiple sclerosis
F20..00	Multiple sclerosis	Multiple sclerosis	684.0	Diagnosis of Multiple sclerosis
F20..11	Disseminated sclerosis	Multiple sclerosis	3440.0	Diagnosis of Multiple sclerosis
F200.00	Multiple sclerosis of the brain stem	Multiple sclerosis	40344.0	Diagnosis of Multiple sclerosis
F201.00	Multiple sclerosis of the spinal cord	Multiple sclerosis	69886.0	Diagnosis of Multiple sclerosis
F202.00	Generalised multiple sclerosis	Multiple sclerosis	23730.0	Diagnosis of Multiple sclerosis
F203.00	Exacerbation of multiple sclerosis	Multiple sclerosis	2298.0	History of Multiple sclerosis
F204.00	Benign multiple sclerosis	Multiple sclerosis	96291.0	Diagnosis of Multiple sclerosis
F206.00	Primary progressive multiple sclerosis	Multiple sclerosis	96607.0	Diagnosis of Multiple sclerosis
F207.00	Relapsing and remitting multiple sclerosis	Multiple sclerosis	95972.0	Diagnosis of Multiple sclerosis
F208.00	Secondary progressive multiple sclerosis	Multiple sclerosis	96246.0	Diagnosis of Multiple sclerosis
F20z.00	Multiple sclerosis NOS	Multiple sclerosis	20493.0	Diagnosis of Multiple sclerosis

C856/2851 Multiple sclerosis - Primary care - Med codes

Rows: 23

Code	Description	Disease	ReadcodeDescr	Readcode
100503.0	History of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis review declined	8IAb.00
106307.0	History of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis monitoring administration	9mD..00
109049.0	History of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis monitoring first letter	9mD0.00
109302.0	History of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis monitoring second letter	9mD1.00
20493.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis NOS	F20z.00
2298.0	History of Multiple sclerosis	Multiple sclerosis	Exacerbation of multiple sclerosis	F203.00
23730.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Generalised multiple sclerosis	F202.00
3440.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Disseminated sclerosis	F20..11
40344.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis of the brain stem	F200.00
43232.0	History of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis multidisciplinary review	666B.00
44985.0	History of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis review	666A.00
48527.0	History of Multiple sclerosis	Multiple sclerosis	Spec serv for pat with multiple sclerosis - enh serv admin	9kG..00
50161.0	History of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis care plan agreed	8CS1.00
684.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis	F20..00
69886.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Multiple sclerosis of the spinal cord	F201.00
95864.0	History of Multiple sclerosis	Multiple sclerosis	Management of multiple sclerosis in stable disability phase	8Cc2.00
95972.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Relapsing and remitting multiple sclerosis	F207.00
96246.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Secondary progressive multiple sclerosis	F208.00
96291.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Benign multiple sclerosis	F204.00
96607.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Primary progressive multiple sclerosis	F206.00
97487.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Management of multiple sclerosis in early disease phase	8Cc1.00
98521.0	History of Multiple sclerosis	Multiple sclerosis	Management of multiple sclerosis in palliative phase	8Cc4.00
98835.0	Diagnosis of Multiple sclerosis	Multiple sclerosis	Management of multiple sclerosis in onset phase	8Cc0.00

C857/2853 Multiple sclerosis - Secondary care - Diagnoses - ICD10 codes

Rows: 1

Code	Description	Disease	Category
G35	Multiple sclerosis	Multiple sclerosis	Diagnosis of Multiple sclerosis

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH63/version/126/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH63/version/126/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH63', '126', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH63/version/126/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH63/version/126/export/codes/?format=json
CSV	site_root/phenotypes/PH63/version/126/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH63', '126', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
126	Multiple sclerosis	ieuan.scanlon	2021-10-06	currently shown