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Hypothyroidism

Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis

Type
Disease or Syndrome
ID
PH633
Version ID
1266
Data Sources
Valid event data range
01/04/2000 - 31/03/2012
Sex
Male
Agreement Date
2015-12-15
Coding system
Read codes v2 OXMIS codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Objectives:

Little is known about the prevalence of comorbidity rates in people with severe mental illness (SMI) in UK primary care. We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.

Design:

Retrospective cohort study from 2000 to 2012.

Setting:

627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.

Participants:

Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.

Outcome measures:

Prevalence rates were calculated for 16 conditions.

Publications

  • Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis, Inequalities in physical comorbidity a longitudinal comparative cohort study of people with severe mental illness in the UK. BMJ Open, 5(e009010), 2015.

Clinical Code List

Rows: 31
Code Description Entity type Coding System (OXMIS Read) Category
C03..00 Congenital hypothyroidism res26: Hypothyroidism Read diagnostic
C03y.00 Other specified congenital hypothyroidism res26: Hypothyroidism Read diagnostic
C03y000 Congenital hypothyroidism with diffuse goitre res26: Hypothyroidism Read diagnostic
C03y100 Congenital hypothyroidism without goitre res26: Hypothyroidism Read diagnostic
C03z.00 Congenital hypothyroidism NOS res26: Hypothyroidism Read diagnostic
C04..00 Acquired hypothyroidism res26: Hypothyroidism Read diagnostic
C04..11 Myxoedema res26: Hypothyroidism Read diagnostic
C04..12 Thyroid deficiency res26: Hypothyroidism Read diagnostic
C04..13 Hypothyroidism res26: Hypothyroidism Read diagnostic
C040.00 Postsurgical hypothyroidism res26: Hypothyroidism Read diagnostic
C040.11 Post ablative hypothyroidism res26: Hypothyroidism Read diagnostic
C041.00 Other postablative hypothyroidism res26: Hypothyroidism Read diagnostic
C041000 Irradiation hypothyroidism res26: Hypothyroidism Read diagnostic
C041z00 Postablative hypothyroidism NOS res26: Hypothyroidism Read diagnostic
C042.00 Iodine hypothyroidism res26: Hypothyroidism Read diagnostic
C043.00 Other iatrogenic hypothyroidism res26: Hypothyroidism Read diagnostic
C043000 Hypothyroidism resulting from para-aminosalicylic acid res26: Hypothyroidism Read diagnostic
C043100 Hypothyroidism resulting from phenylbutazone res26: Hypothyroidism Read diagnostic
C043200 Hypothyroidism resulting from resorcinol res26: Hypothyroidism Read diagnostic
C043z00 Iatrogenic hypothyroidism NOS res26: Hypothyroidism Read diagnostic
C044.00 Postinfectious hypothyroidism res26: Hypothyroidism Read diagnostic
C045.00 Acquired atrophy of thyroid res26: Hypothyroidism Read diagnostic
C046.00 Autoimmune myxoedema res26: Hypothyroidism Read diagnostic
C04y.00 Other acquired hypothyroidism res26: Hypothyroidism Read diagnostic
C04z.00 Hypothyroidism NOS res26: Hypothyroidism Read diagnostic
C04z.11 Pretibial myxoedema - hypothyroid res26: Hypothyroidism Read diagnostic
C04z.12 Thyroid insufficiency res26: Hypothyroidism Read diagnostic
C04z.13 Hypothyroid goitre, acquired res26: Hypothyroidism Read diagnostic
C04z000 Premature puberty due to hypothyroidism res26: Hypothyroidism Read diagnostic
C04z100 Myxoedema coma res26: Hypothyroidism Read diagnostic
Cyu1100 [X]Other sp cified hypothyroidism res26: Hypothyroidism Read diagnostic
Rows: 3
Code Description Entity type Coding System (OXMIS Read) Category
243 HYPOTHYROIDISM CONGENITAL res26: Hypothyroidism OXMIS diagnostic
244 AC HYPOTHYROIDISM ACQUIRED res26: Hypothyroidism OXMIS diagnostic
244 AG HYPOTHYROIDISM COMPENSATED res26: Hypothyroidism OXMIS diagnostic

API

To Export Phenotype Details:

Format API
XML site_root/api/v1/public/phenotypes/PH633/version/1266/detail/?format=xml
JSON site_root/api/v1/public/phenotypes/PH633/version/1266/detail/?format=json
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get details of phenotype

details = get_phenotype_detail_by_version('PH633', '1266', api_client=client)

To Export Phenotype Code List:

Format API
XML site_root/api/v1/public/phenotypes/PH633/version/1266/export/codes/?format=xml
JSON site_root/api/v1/public/phenotypes/PH633/version/1266/export/codes/?format=json
CSV site_root/phenotypes/PH633/version/1266/export/codes/
R Package

# Download here

library(ConceptLibraryClient)


# Connect to API

client = connect_to_API(public=TRUE)


# Get codelists of phenotype

codelists = get_phenotype_code_list('PH633', '1266', api_client=client)

Version History

Version
ID
Name Owner Publish date
1266 Hypothyroidism ieuan.scanlon 2021-10-06 currently shown

Export - export all codes into a csv file/JSON/XML for the current phenotype version.

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