Phenotype Library | phenotype: Hypothyroidism

Hypothyroidism

Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis

PH633

Version ID

1266

Type

Disease or Syndrome

Data Sources

CPRD GOLD

Valid event data range

01/04/2000 - 31/03/2012

Sex

♂ Male

Agreement Date

2015-12-15

Coding system

Read codes v2 OXMIS codes

Collections

ClinicalCodes Repository Phenotype Library

Definition

Objectives:

Little is known about the prevalence of comorbidity rates in people with severe mental illness (SMI) in UK primary care. We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.

Design:

Retrospective cohort study from 2000 to 2012.

Setting:

627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.

Participants:

Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.

Outcome measures:

Prevalence rates were calculated for 16 conditions.

Publications

Siobhan Reilly, Ivan Olier, Claire Planner, Tim Doran, David Reeves, Darren M Ashcroft, Linda Gask, Evangelos Kontopantelis, Inequalities in physical comorbidity a longitudinal comparative cohort study of people with severe mental illness in the UK. BMJ Open, 5(e009010), 2015.

Clinical Code List

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C2048/5234 Hypothyroidism - Primary Care - Read codes v2

Rows: 31

Code	Description	Entity type	Coding System (OXMIS Read)	Category
C03..00	Congenital hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C03y.00	Other specified congenital hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C03y000	Congenital hypothyroidism with diffuse goitre	res26: Hypothyroidism	Read	diagnostic
C03y100	Congenital hypothyroidism without goitre	res26: Hypothyroidism	Read	diagnostic
C03z.00	Congenital hypothyroidism NOS	res26: Hypothyroidism	Read	diagnostic
C04..00	Acquired hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C04..11	Myxoedema	res26: Hypothyroidism	Read	diagnostic
C04..12	Thyroid deficiency	res26: Hypothyroidism	Read	diagnostic
C04..13	Hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C040.00	Postsurgical hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C040.11	Post ablative hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C041.00	Other postablative hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C041000	Irradiation hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C041z00	Postablative hypothyroidism NOS	res26: Hypothyroidism	Read	diagnostic
C042.00	Iodine hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C043.00	Other iatrogenic hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C043000	Hypothyroidism resulting from para-aminosalicylic acid	res26: Hypothyroidism	Read	diagnostic
C043100	Hypothyroidism resulting from phenylbutazone	res26: Hypothyroidism	Read	diagnostic
C043200	Hypothyroidism resulting from resorcinol	res26: Hypothyroidism	Read	diagnostic
C043z00	Iatrogenic hypothyroidism NOS	res26: Hypothyroidism	Read	diagnostic
C044.00	Postinfectious hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C045.00	Acquired atrophy of thyroid	res26: Hypothyroidism	Read	diagnostic
C046.00	Autoimmune myxoedema	res26: Hypothyroidism	Read	diagnostic
C04y.00	Other acquired hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C04z.00	Hypothyroidism NOS	res26: Hypothyroidism	Read	diagnostic
C04z.11	Pretibial myxoedema - hypothyroid	res26: Hypothyroidism	Read	diagnostic
C04z.12	Thyroid insufficiency	res26: Hypothyroidism	Read	diagnostic
C04z.13	Hypothyroid goitre, acquired	res26: Hypothyroidism	Read	diagnostic
C04z000	Premature puberty due to hypothyroidism	res26: Hypothyroidism	Read	diagnostic
C04z100	Myxoedema coma	res26: Hypothyroidism	Read	diagnostic
Cyu1100	[X]Other sp cified hypothyroidism	res26: Hypothyroidism	Read	diagnostic

C2049/5236 Hypothyroidism - Primary Care - OXMIS codes

Rows: 3

Code	Description	Entity type	Coding System (OXMIS Read)	Category
243	HYPOTHYROIDISM CONGENITAL	res26: Hypothyroidism	OXMIS	diagnostic
244 AC	HYPOTHYROIDISM ACQUIRED	res26: Hypothyroidism	OXMIS	diagnostic
244 AG	HYPOTHYROIDISM COMPENSATED	res26: Hypothyroidism	OXMIS	diagnostic

API

To Export Phenotype Details:

Format	API
XML	site_root/api/v1/public/phenotypes/PH633/version/1266/detail/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH633/version/1266/detail/?format=json
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get details of phenotype details = get_phenotype_detail_by_version('PH633', '1266', api_client=client)`

To Export Phenotype Code List:

Format	API
XML	site_root/api/v1/public/phenotypes/PH633/version/1266/export/codes/?format=xml
JSON	site_root/api/v1/public/phenotypes/PH633/version/1266/export/codes/?format=json
CSV	site_root/phenotypes/PH633/version/1266/export/codes/
R Package	`# Download here library(ConceptLibraryClient) # Connect to API client = connect_to_API(public=TRUE) # Get codelists of phenotype codelists = get_phenotype_code_list('PH633', '1266', api_client=client)`

Version History

Version ID	Name	Owner	Publish date
1266	Hypothyroidism	ieuan.scanlon	2021-10-06	currently shown