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Gastroprotection

S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Aschroft

Type
Drug
ID
PH660
Version ID
1320
Data Sources
Valid event data range
Start - 01/02/2013
Sex
Female, Male
Agreement Date
2015-11-03
Coding system
GPRD product codes
Tags /Collections
ClinicalCodes Repository Phenotype Library

Definition

Study question:

What is the prevalence of different types of potentially hazardous prescribing in general practice in the United Kingdom, and what is the variation between practices?

Methods:

A cross sectional study included all adult patients potentially at risk of a prescribing or monitoring error defined by a combination of diagnoses and prescriptions in 526 general practices contributing to the Clinical Practice Research Datalink (CPRD) up to 1 April 2013. Primary outcomes were the prevalence of potentially hazardous prescriptions of anticoagulants, anti-platelets, NSAIDs, β blockers, glitazones, metformin, digoxin, antipsychotics, combined hormonal contraceptives, and oestrogens and monitoring by blood test less frequently than recommended for patients with repeated prescriptions of angiotensin converting enzyme inhibitors and loop diuretics, amiodarone, methotrexate, lithium, or warfarin.

Study answer and limitations:

49 927 of 949 552 patients at risk triggered at least one prescribing indicator (5.26%, 95% confidence interval 5.21% to 5.30%) and 21 501 of 182 721 (11.8%, 11.6% to 11.9%) triggered at least one monitoring indicator. The prevalence of different types of potentially hazardous prescribing ranged from almost zero to 10.2%, and for inadequate monitoring ranged from 10.4% to 41.9%. Older patients and those prescribed multiple repeat medications had significantly higher risks of triggering a prescribing indicator whereas younger patients with fewer repeat prescriptions had significantly higher risk of triggering a monitoring indicator. There was high variation between practices for some indicators. Though prescribing safety indicators describe prescribing patterns that can increase the risk of harm to the patient and should generally be avoided, there will always be exceptions where the indicator is clinically justified. Furthermore there is the possibility that some information is not captured by CPRD for some practices—for example, INR results in patients receiving warfarin.

What this study adds:

The high prevalence for certain indicators emphasises existing prescribing risks and the need for their appropriate consideration within primary care, particularly for older patients and those taking multiple medications. The high variation between practices indicates potential for improvement through targeted practice level intervention.

Publications

  • S Jill Stocks, Evangelos Kontopantelis, Artur Akbarov, Sarah Rodgers, Anthony J Avery, Darren M Ashcroft, Examining variations in prescribing safety in UK general practice cross sectional study using the Clinical Practice Research Datalink. BMJ, 351(h5501), 2015.

Clinical Code List

Rows: 348
Code Description Coding System (CPRD_product_code) Entity type Category
10098 Zoton 30mg gastro-resistant granules sachets (Wyeth Pharmaceuticals) CPRD_product_code res25: gastroprotection drug
10555 Famotidine 40mg tablets CPRD_product_code res25: gastroprotection drug
10556 Algitec Liquid (GlaxoSmithKline Consumer Healthcare) CPRD_product_code res25: gastroprotection drug
10622 Algitec Chewable tablet (GlaxoSmithKline Consumer Healthcare) CPRD_product_code res25: gastroprotection drug
10746 Pepcid 40mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res25: gastroprotection drug
1229 Zantac 150mg tablets (GlaxoSmithKline UK Ltd) CPRD_product_code res25: gastroprotection drug
1230 Cimetidine 800mg tablets CPRD_product_code res25: gastroprotection drug
1232 Losec 20mg gastro-resistant capsules (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
13015 Losec MUPS 10mg gastro-resistant tablets (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
13282 Omeprazole 5mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
13378 Zantac 300mg effervescent tablets (GlaxoSmithKline UK Ltd) CPRD_product_code res25: gastroprotection drug
13579 Zinga 150mg capsules (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
1367 Ranitidine 150mg effervescent tablets CPRD_product_code res25: gastroprotection drug
1394 Ranitidine 75mg/5ml oral solution sugar free CPRD_product_code res25: gastroprotection drug
1451 Omeprazole 40mg gastro-resistant capsules CPRD_product_code res25: gastroprotection drug
15275 Omeprazole 10mg gastro-resistant capsules (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
15277 Gavilast-P 75mg tablets (Reckitt Benckiser Healthcare (UK) Ltd) CPRD_product_code res25: gastroprotection drug
1556 Ranitidine 300mg tablets CPRD_product_code res25: gastroprotection drug
16034 Gavilast 75mg tablets (Reckitt Benckiser Healthcare (UK) Ltd) CPRD_product_code res25: gastroprotection drug
16092 Ranitidine 75mg effervescent tablets sugar free CPRD_product_code res25: gastroprotection drug
16195 Zinga 300mg capsules (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
162 Arthrotec 50 gastro-resistant tablets (Pfizer Ltd) CPRD_product_code res25: gastroprotection drug
1692 Diclofenac sodium 50mg gastro-resistant / Misoprostol 200microgram tablets CPRD_product_code res25: gastroprotection drug
17108 Zantac 75 tablets (Omega Pharma Ltd) CPRD_product_code res25: gastroprotection drug
17162 Galenamet 400mg tablets (Galen Ltd) CPRD_product_code res25: gastroprotection drug
18 Omeprazole 20mg gastro-resistant capsules CPRD_product_code res25: gastroprotection drug
18225 Esomeprazole 40mg powder for solution for injection vials CPRD_product_code res25: gastroprotection drug
18426 Acid-Eze 200mg tablets (Manx Healthcare Ltd) CPRD_product_code res25: gastroprotection drug
18489 Zantac 75 Relief tablets (Omega Pharma Ltd) CPRD_product_code res25: gastroprotection drug
19249 Ranitidine 300mg tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
19272 Ranitidine 150mg tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
19277 Axid 300mg capsules (Flynn Pharma Ltd) CPRD_product_code res25: gastroprotection drug
1941 Pariet 20mg gastro-resistant tablets (Eisai Ltd) CPRD_product_code res25: gastroprotection drug
1947 Zoton 15mg gastro-resistant capsules (Wyeth Pharmaceuticals) CPRD_product_code res25: gastroprotection drug
1963 Ranitidine 75mg tablets CPRD_product_code res25: gastroprotection drug
1977 Rabeprazole 10mg gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
1986 Pantoprazole 40mg gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
20011 Galenamet 800mg Tablet (Galen Ltd) CPRD_product_code res25: gastroprotection drug
20360 Tagamet 200mg/5ml syrup (Chemidex Pharma Ltd) CPRD_product_code res25: gastroprotection drug
2057 Cimetidine 200mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
21 Ranitidine 150mg tablets CPRD_product_code res25: gastroprotection drug
2151 Rabeprazole 20mg gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
21544 Rantec 300 tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
21565 Ranitil 150mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res25: gastroprotection drug
21602 Raciran 300 tablets (Opus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21823 Acitak 400mg tablets (Opus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21825 Ultec 400mg tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
21853 Peptimax 400 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21871 Peptimax 200mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21893 Raciran 150 tablets (Opus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21894 Zaedoc 150 tablets (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21901 Zaedoc 300 300mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21988 Ultec 200mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
21991 Tagadine 400mg Tablet (OPD Pharm) CPRD_product_code res25: gastroprotection drug
22037 Tagamet 400mg tablets (Chemidex Pharma Ltd) CPRD_product_code res25: gastroprotection drug
225 Nizatidine 300mg capsules CPRD_product_code res25: gastroprotection drug
22635 Galenamet 200mg Tablet (Galen Ltd) CPRD_product_code res25: gastroprotection drug
22643 Zita 400mg tablets (LPC Medical (UK) Ltd) CPRD_product_code res25: gastroprotection drug
23132 Pepcid AC 10mg Chewable tablet (MSD Thomas Morson Pharmaceuticals) CPRD_product_code res25: gastroprotection drug
2387 Arthrotec 75 gastro-resistant tablets (Pfizer Ltd) CPRD_product_code res25: gastroprotection drug
24049 Cimetidine 100mg with Sodium alginate 250mg/5ml suspension CPRD_product_code res25: gastroprotection drug
24092 Tagamet 200mg tablets (Chemidex Pharma Ltd) CPRD_product_code res25: gastroprotection drug
24301 Tagamet 100mg Tablet (GlaxoSmithKline Consumer Healthcare) CPRD_product_code res25: gastroprotection drug
24302 Rantec 150 tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
24360 Heartburn relief 10mg Tablet (Galpharm International Ltd) CPRD_product_code res25: gastroprotection drug
24704 Tagamet dual action 100mg + 250mg/5ml Liquid (GlaxoSmithKline Consumer Healthcare) CPRD_product_code res25: gastroprotection drug
25271 Peptimax 800mg Tablet (Ashbourne Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
25360 Histac 150mg tablets (Ranbaxy (UK) Ltd) CPRD_product_code res25: gastroprotection drug
25404 Famotidine 10mg Tablet CPRD_product_code res25: gastroprotection drug
25596 Nexium I.V 40mg powder for solution for injection vials (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
25873 Cimetidine 200mg with alginic acid 500mg tablets CPRD_product_code res25: gastroprotection drug
26170 Ranitidine 150mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
26208 Acitak 200mg Tablet (Opus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
26537 Omeran 20mg gastro-resistant tablets (Ranbaxy (UK) Ltd) CPRD_product_code res25: gastroprotection drug
26699 Tagamet 100mg Tablet (AHA Sales Services Ltd) CPRD_product_code res25: gastroprotection drug
26949 Ranitil 300mg tablets (Tillomed Laboratories Ltd) CPRD_product_code res25: gastroprotection drug
27024 Ultec 800mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
27288 Axid 150mg capsules (Flynn Pharma Ltd) CPRD_product_code res25: gastroprotection drug
27465 Zita 800mg Tablet (Eastern Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
276 Losec 10mg gastro-resistant capsules (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
27698 Zantac 75 Dissolve tablets (GlaxoSmithKline Consumer Healthcare) CPRD_product_code res25: gastroprotection drug
27808 Phimetin 800mg Tablet (BHR Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
28047 Cimetidine 200mg/5ml oral solution sugar free CPRD_product_code res25: gastroprotection drug
28050 Zita 200mg Tablet (Eastern Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
28787 Phimetin 200mg Tablet (BHR Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
29048 Tagamet 800mg tablets (Chemidex Pharma Ltd) CPRD_product_code res25: gastroprotection drug
29148 Phimetin 400mg Tablet (BHR Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
29457 Omeprazole 20mg gastro-resistant capsules (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
29468 Omeprazole 40mg gastro-resistant capsules (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
30 Lansoprazole 15mg gastro-resistant capsules CPRD_product_code res25: gastroprotection drug
30241 Ranitidine 150mg dispersible tablet CPRD_product_code res25: gastroprotection drug
30863 Ranitidine 150mg Tablet (Genus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
30926 Omeprazole 10mg gastro-resistant capsules (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
31213 Omeran 10mg gastro-resistant tablets (Ranbaxy (UK) Ltd) CPRD_product_code res25: gastroprotection drug
31492 Histac 300mg tablets (Ranbaxy (UK) Ltd) CPRD_product_code res25: gastroprotection drug
31533 Ranitidine 150mg Tablet (Genus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
31846 Cimetidine 4mg/ml infusion CPRD_product_code res25: gastroprotection drug
32342 Ranitidine indigestion relief 75mg Tablet (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
32747 Cimetidine 400mg Tablet (Berk Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
3276 Tagamet 800mg Tablet (GlaxoSmithKline UK Ltd) CPRD_product_code res25: gastroprotection drug
32859 Zantac 75 Relief Dissolve tablets (Omega Pharma Ltd) CPRD_product_code res25: gastroprotection drug
32914 Omeprazole 10mg gastro-resistant tablets (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
32919 Omeprazole 20mg gastro-resistant tablets (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
32924 Omeprazole 20mg gastro-resistant tablets (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
33022 Zanprol 10mg gastro-resistant tablets (Omega Pharma Ltd) CPRD_product_code res25: gastroprotection drug
33088 Cimetidine 400mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
33325 Cimetidine 400mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
33326 Omeprazole 10mg gastro-resistant tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
33565 Omeprazole 20mg Tablet (Neo Laboratories Ltd) CPRD_product_code res25: gastroprotection drug
33667 Cimetidine 400mg tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
34276 Ranitidine 75mg/5ml oral solution sugar free (Rosemont Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
34295 Ranitidine 150mg tablets (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34301 Ranitidine 150mg effervescent tablets (Sovereign Medical Ltd) CPRD_product_code res25: gastroprotection drug
34302 Omeprazole 20mg gastro-resistant capsules (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34321 Nizatidine 150mg capsules (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34332 Omeprazole 10mg gastro-resistant capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
34403 Ranitidine 150mg tablets (Ranbaxy (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34411 Omeprazole 20mg gastro-resistant capsules (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
34433 Ranitidine 150mg Tablet (Dominion Pharma) CPRD_product_code res25: gastroprotection drug
34450 Ranitidine 150mg effervescent tablets (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
34480 Ranitidine 150mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
34511 Nizatidine 150mg capsules (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
34531 Ranitidine 300mg tablets (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34556 Cimetidine 200mg tablets (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34568 Omeprazole 10mg gastro-resistant capsules (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34571 Omeprazole 10mg gastro-resistant capsules (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
34577 Omeprazole 20mg gastro-resistant capsules (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
34708 Ranitidine 150mg Tablet (Warrick) CPRD_product_code res25: gastroprotection drug
34788 Cimetidine 200mg tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
34791 Omeprazole 40mg gastro-resistant capsules (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
34792 Omeprazole 10mg gastro-resistant capsules (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
34812 Omeprazole 20mg Gastro-resistant capsule (Niche Generics Ltd) CPRD_product_code res25: gastroprotection drug
34841 Omeprazole 20mg gastro-resistant capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
34843 Omeprazole 20mg gastro-resistant capsules (Dexcel-Pharma Ltd) CPRD_product_code res25: gastroprotection drug
34886 Ranitidine 150mg tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
34967 Omeprazole 20mg gastro-resistant capsules (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
34984 Heartburn relief 10mg Tablet (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
35101 Omeprazole 10mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
35257 Omeprazole 40mg gastro-resistant capsules (Dr Reddy's Laboratories (UK) Ltd) CPRD_product_code res25: gastroprotection drug
35383 Omeprazole 20mg gastro-resistant capsules (Dr Reddy's Laboratories (UK) Ltd) CPRD_product_code res25: gastroprotection drug
35698 Mepradec 20mg gastro-resistant capsules (Discovery Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
35699 Mepradec 10mg gastro-resistant capsules (Discovery Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
36046 Omeprazole 40mg Gastro-resistant capsule (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
36892 Omeprazole 10mg gastro-resistant tablets (Dexcel-Pharma Ltd) CPRD_product_code res25: gastroprotection drug
37815 Lansoprazole 30mg gastro-resistant capsules (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
3857 Tagamet 200mg Tablet (GlaxoSmithKline UK Ltd) CPRD_product_code res25: gastroprotection drug
39 Lansoprazole 30mg gastro-resistant capsules CPRD_product_code res25: gastroprotection drug
3967 Zantac 150mg Dispersible tablet (Glaxo Laboratories Ltd) CPRD_product_code res25: gastroprotection drug
39904 Lansoprazole 15mg gastro-resistant capsules (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
40152 Ranitidine 300mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
40430 Tagamet 4mg/ml Infusion (GlaxoSmithKline UK Ltd) CPRD_product_code res25: gastroprotection drug
40759 Lansoprazole 15mg gastro-resistant capsules (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
40896 Lansoprazole 30mg gastro-resistant capsules (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
41364 Ketoprofen 100mg / Omeprazole 20mg modified-release capsules CPRD_product_code res25: gastroprotection drug
41365 Axorid 200mg/20mg modified-release capsules (Meda Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
41366 Axorid 100mg/20mg modified-release capsules (Meda Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
41367 Ketoprofen 200mg / Omeprazole 20mg modified-release capsules CPRD_product_code res25: gastroprotection drug
41454 Nexium 10mg gastro-resistant granules sachets (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
41501 Esomeprazole 10mg gastro-resistant granules sachets CPRD_product_code res25: gastroprotection drug
41534 Cimetidine 800mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
41536 Ranitidine 300mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
41568 Cimetidine 400mg tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
41587 Cimetidine 200mg tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
41588 Cimetidine 200mg tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
41589 Cimetidine 200mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
41631 Cimetidine 800mg tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
41648 Cimetidine 800mg tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
41684 Cimetidine 800mg tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
41895 Acitak 800mg Tablet (Opus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
41992 Omeprazole 10mg gastro-resistant tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
42088 Nizatidine 300mg capsules (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
42091 Omeprazole 20mg gastro-resistant tablets (Dexcel-Pharma Ltd) CPRD_product_code res25: gastroprotection drug
42114 Omeran 40mg gastro-resistant tablets (Ranbaxy (UK) Ltd) CPRD_product_code res25: gastroprotection drug
42382 Lansoprazole 30mg gastro-resistant capsules (Almus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
42532 Lansoprazole 30mg gastro-resistant capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
42533 Omeprazole 20mg gastro-resistant capsules (Focus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
4254 Cytotec 200microgram tablets (Pfizer Ltd) CPRD_product_code res25: gastroprotection drug
42730 Lansoprazole 30mg gastro-resistant capsules (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
42736 Omeprazole 20mg gastro-resistant tablets (Kent Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
42898 Omeprazole 10mg gastro-resistant tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
42900 Omeprazole 20mg gastro-resistant tablets (IVAX Pharmaceuticals UK Ltd) CPRD_product_code res25: gastroprotection drug
43057 Lansoprazole 30mg gastro-resistant capsules (Generics (UK) Ltd) CPRD_product_code res25: gastroprotection drug
43529 Ranitidine 150mg Tablet (C P Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
43948 Esomeprazole 40mg gastro-resistant capsules CPRD_product_code res25: gastroprotection drug
43957 Omeprazole 20mg gastro-resistant tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
43995 Esomeprazole 20mg gastro-resistant capsules CPRD_product_code res25: gastroprotection drug
44023 Pantoloc Control 20mg gastro-resistant tablets (Novartis Consumer Health UK Ltd) CPRD_product_code res25: gastroprotection drug
44252 Omeprazole 20mg/5ml Oral suspension (Martindale Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
4451 Dyspamet chewtab 200 200mg Chewable tablet (Goldshield Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
446 Cimetidine 200mg tablets CPRD_product_code res25: gastroprotection drug
4468 Ranitidine 300mg effervescent tablets CPRD_product_code res25: gastroprotection drug
44753 Lansoprazole 30mg gastro-resistant capsules (Consilient Health Ltd) CPRD_product_code res25: gastroprotection drug
44800 Naproxen 500mg / Esomeprazole 20mg modified-release tablets CPRD_product_code res25: gastroprotection drug
44986 Vimovo 500mg/20mg modified-release tablets (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
45173 Omeprazole 20mg gastro-resistant capsules (Almus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
45214 Ranitidine 150mg tablets (Sterwin Medicines) CPRD_product_code res25: gastroprotection drug
45232 Ranitidine 150mg tablets (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
45294 Ranitidine 300mg Effervescent tablet (Ratiopharm UK Ltd) CPRD_product_code res25: gastroprotection drug
45322 Ranitidine 300mg Tablet (Galen Ltd) CPRD_product_code res25: gastroprotection drug
4654 Losec 40mg gastro-resistant capsules (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
46744 Emozul 20mg gastro-resistant capsules (Consilient Health Ltd) CPRD_product_code res25: gastroprotection drug
46745 Emozul 40mg gastro-resistant capsules (Consilient Health Ltd) CPRD_product_code res25: gastroprotection drug
4742 Axid 300mg Capsule (Eli Lilly and Company Ltd) CPRD_product_code res25: gastroprotection drug
47511 Omeprazole 5mg/5ml Oral suspension (Martindale Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
47909 Lansoprazole 30mg gastro-resistant capsules (Arrow Generics Ltd) CPRD_product_code res25: gastroprotection drug
47934 Cimetidine 400mg tablets (Dexcel-Pharma Ltd) CPRD_product_code res25: gastroprotection drug
48063 Lansoprazole 30mg gastro-resistant capsules (Zentiva) CPRD_product_code res25: gastroprotection drug
4880 Diclofenac sodium 75mg gastro-resistant / Misoprostol 200microgram tablets CPRD_product_code res25: gastroprotection drug
4885 Axid 150mg Capsule (Eli Lilly and Company Ltd) CPRD_product_code res25: gastroprotection drug
49163 Omeprazole 20mg gastro-resistant capsules (Zentiva) CPRD_product_code res25: gastroprotection drug
49209 Lansoprazole 7.5mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
4921 Omeprazole 20mg dispersible gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
49375 Pantoprazole 20mg gastro-resistant tablets (Nycomed UK Ltd) CPRD_product_code res25: gastroprotection drug
49433 Omeprazole 40mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
4955 Omeprazole 40mg dispersible gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
49584 Omeprazole 8mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
50269 Arthrotec 75 gastro-resistant tablets (Mawdsley-Brooks & Company Ltd) CPRD_product_code res25: gastroprotection drug
50365 Omeprazole 8.5mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
50372 Omeprazole 15mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
50492 Lansoprazole 30mg gastro-resistant capsules (Sigma Pharmaceuticals Plc) CPRD_product_code res25: gastroprotection drug
51260 Omeprazole 20mg gastro-resistant capsules (Arrow Generics Ltd) CPRD_product_code res25: gastroprotection drug
51290 Zoton FasTab 15mg (Mawdsley-Brooks & Company Ltd) CPRD_product_code res25: gastroprotection drug
51357 Omeprazole 15mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
51548 Nexium 20mg gastro-resistant tablets (Mawdsley-Brooks & Company Ltd) CPRD_product_code res25: gastroprotection drug
51549 Ranitidine 5mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
5178 Esomeprazole 20mg gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
51801 Ranitidine 300mg tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
51804 Pantoprazole 20mg gastro-resistant tablets (Arrow Generics Ltd) CPRD_product_code res25: gastroprotection drug
519 Zoton 30mg gastro-resistant capsules (Wyeth Pharmaceuticals) CPRD_product_code res25: gastroprotection drug
5232 Omeprazole 10mg dispersible gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
5236 Losec MUPS 20mg gastro-resistant tablets (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
52379 Omeprazole 25mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
52612 Losec 20mg gastro-resistant capsules (Lexon (UK) Ltd) CPRD_product_code res25: gastroprotection drug
5269 Nexium 20mg gastro-resistant tablets (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
52691 Ranitidine 18mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
52866 Omeprazole 4mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
52971 Losec MUPS 10mg gastro-resistant tablets (Lexon (UK) Ltd) CPRD_product_code res25: gastroprotection drug
53317 Ranitidine 75mg/5ml oral solution sugar free (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
53333 Ranitidine 75mg tablets (Vantage) CPRD_product_code res25: gastroprotection drug
53335 Ranitidine 150mg tablets (Accord Healthcare Ltd) CPRD_product_code res25: gastroprotection drug
53337 Omeprazole 10mg gastro-resistant capsules (Phoenix Healthcare Distribution Ltd) CPRD_product_code res25: gastroprotection drug
53518 Omeprazole 2mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
5358 Lansoprazole 30mg gastro-resistant granules sachets CPRD_product_code res25: gastroprotection drug
53616 Lansoprazole 5mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
53843 Esomeprazole 40mg gastro-resistant tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
53871 Lansoprazole 30mg gastro-resistant capsules (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
53947 Ranitidine 75mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
54101 Ranitidine 16mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
54121 Lansoprazole 15mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
54188 Lansoprazole 30mg gastro-resistant capsules (Phoenix Healthcare Distribution Ltd) CPRD_product_code res25: gastroprotection drug
5419 Pantoprazole 20mg gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
54253 Ranitidine 75mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
54539 Ranitidine 10mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
54683 Mezzopram 10mg gastro-resistant tablets (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
54693 Pantoprazole 20mg gastro-resistant tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
54746 Ranitidine 10mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
54784 Ranitidine 150mg tablets (Medreich Plc) CPRD_product_code res25: gastroprotection drug
54939 Lansoprazole 15mg gastro-resistant capsules (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res25: gastroprotection drug
55168 Omeprazole 10mg dispersible gastro-resistant tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
55439 Lansoprazole 15mg gastro-resistant capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
55468 Omeprazole 20mg gastro-resistant capsules (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res25: gastroprotection drug
55647 Ranitidine 20mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
55665 Ranitidine 5mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
55700 Omeprazole 3mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
55744 Omeprazole 20mg gastro-resistant capsules (Zanza Laboratories Ltd) CPRD_product_code res25: gastroprotection drug
55745 Losec 10mg gastro-resistant capsules (Lexon (UK) Ltd) CPRD_product_code res25: gastroprotection drug
55857 Ranitidine 75mg tablets (Galpharm International Ltd) CPRD_product_code res25: gastroprotection drug
55936 Ranitidine 1.5mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
55991 Ranitidine 3mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
5604 Esomeprazole 40mg gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
56235 Omeprazole 12.5mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
56414 Ranitidine 3mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
56432 Omeprazole 6.8mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
56433 Omeprazole 35mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
56479 Losec 20mg gastro-resistant capsules (Waymade Healthcare Plc) CPRD_product_code res25: gastroprotection drug
56569 Ranitidine 75mg/5ml oral solution sugar free (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
56614 Ranitidine 25mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
56816 Ranitidine 50mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
56895 Omeprazole 50mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
57158 Lansoprazole 30mg gastro-resistant capsules (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res25: gastroprotection drug
57177 Omeprazole 20mg gastro-resistant capsules (Bristol Laboratories Ltd) CPRD_product_code res25: gastroprotection drug
57236 Cimetidine 400mg tablets (Almus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
57311 Esomeprazole 20mg gastro-resistant capsules (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
57504 Zoton FasTab 30mg (Waymade Healthcare Plc) CPRD_product_code res25: gastroprotection drug
57528 Losec 20mg gastro-resistant capsules (Dowelhurst Ltd) CPRD_product_code res25: gastroprotection drug
57541 Omeprazole 10mg gastro-resistant tablets (Sterwin Medicines) CPRD_product_code res25: gastroprotection drug
57566 Omeprazole 20mg dispersible gastro-resistant tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
57572 Zoton 15mg gastro-resistant capsules (Dowelhurst Ltd) CPRD_product_code res25: gastroprotection drug
57648 Omeprazole 10mg gastro-resistant capsules (Dr Reddy's Laboratories (UK) Ltd) CPRD_product_code res25: gastroprotection drug
57738 Omeprazole 4mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
57909 Ranitidine 150mg effervescent tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
58030 Rabeprazole 10mg gastro-resistant tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
58066 Omeprazole 8mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
58216 Omeprazole 20mg gastro-resistant capsules (Kent Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
58236 Mezzopram 20mg gastro-resistant tablets (Sandoz Ltd) CPRD_product_code res25: gastroprotection drug
58244 Ranitidine 75mg/5ml oral solution sugar free (Almus Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
58332 Omeprazole 20mg gastro-resistant capsules (Somex Pharma) CPRD_product_code res25: gastroprotection drug
58334 Ranitidine 75mg tablets (Medreich Plc) CPRD_product_code res25: gastroprotection drug
5834 Pariet 10mg gastro-resistant tablets (Eisai Ltd) CPRD_product_code res25: gastroprotection drug
58344 Omeprazole 50mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
58415 Diclofenac sodium 50mg gastro-resistant / Misoprostol 200microgram tablets (A A H Pharmaceuticals Lt CPRD_product_code res25: gastroprotection drug
58475 Rabeprazole 20mg gastro-resistant tablets (Zentiva) CPRD_product_code res25: gastroprotection drug
58679 Lansoprazole 15mg gastro-resistant capsules (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
58711 Ranitidine 150mg tablets (Boston Healthcare Ltd) CPRD_product_code res25: gastroprotection drug
58842 Misofen 75mg / 200microgram gastro-resistant tablets (Morningside Healthcare Ltd) CPRD_product_code res25: gastroprotection drug
58946 Omeprazole 10mg gastro-resistant capsules (Waymade Healthcare Plc) CPRD_product_code res25: gastroprotection drug
59106 Lansoprazole 30mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
59135 Omeprazole 2.5mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
59296 Rabeprazole 10mg gastro-resistant tablets (Zentiva) CPRD_product_code res25: gastroprotection drug
59390 Pantoprazole 40mg gastro-resistant tablets (Nycomed UK Ltd) CPRD_product_code res25: gastroprotection drug
59394 Misoprostol 400microgram tablets CPRD_product_code res25: gastroprotection drug
59404 Lansoprazole 30mg gastro-resistant capsules (Sovereign Medical Ltd) CPRD_product_code res25: gastroprotection drug
59547 Omeprazole 40mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
59586 Lansoprazole 30mg gastro-resistant capsules (Kent Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
59711 Pantoprazole 20mg gastro-resistant tablets (Teva UK Ltd) CPRD_product_code res25: gastroprotection drug
59725 Omeprazole 25mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
60230 Omeprazole 10mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
60403 Omeprazole 20mg/5ml oral solution CPRD_product_code res25: gastroprotection drug
60409 Omeprazole 20mg dispersible gastro-resistant tablets (Waymade Healthcare Plc) CPRD_product_code res25: gastroprotection drug
60537 Lansoprazole 30mg gastro-resistant capsules (DE Pharmaceuticals) CPRD_product_code res25: gastroprotection drug
60588 Rabeprazole 20mg gastro-resistant tablets (Alliance Healthcare (Distribution) Ltd) CPRD_product_code res25: gastroprotection drug
60590 Rabeprazole 20mg gastro-resistant tablets (Actavis UK Ltd) CPRD_product_code res25: gastroprotection drug
60615 Lansoprazole 30mg orodispersible tablets (A A H Pharmaceuticals Ltd) CPRD_product_code res25: gastroprotection drug
6063 Zoton FasTab 30mg (Pfizer Ltd) CPRD_product_code res25: gastroprotection drug
6114 Omeprazole 20mg gastro-resistant tablets CPRD_product_code res25: gastroprotection drug
6165 Protium 20mg gastro-resistant tablets (Nycomed UK Ltd) CPRD_product_code res25: gastroprotection drug
6245 Lansoprazole 15mg orodispersible tablets CPRD_product_code res25: gastroprotection drug
6291 Zoton FasTab 15mg (Pfizer Ltd) CPRD_product_code res25: gastroprotection drug
6300 Lansoprazole 30mg orodispersible tablets CPRD_product_code res25: gastroprotection drug
6490 Nexium 40mg gastro-resistant tablets (AstraZeneca UK Ltd) CPRD_product_code res25: gastroprotection drug
6727 Protium 40mg gastro-resistant tablets (Nycomed UK Ltd) CPRD_product_code res25: gastroprotection drug
68 Cimetidine 400mg tablets CPRD_product_code res25: gastroprotection drug
690 Nizatidine 150mg capsules CPRD_product_code res25: gastroprotection drug
7255 Omeprazole 20mg/5ml oral suspension CPRD_product_code res25: gastroprotection drug
7666 Zantac 300mg tablets (GlaxoSmithKline UK Ltd) CPRD_product_code res25: gastroprotection drug
773 Misoprostol 200microgram tablets CPRD_product_code res25: gastroprotection drug
7848 Tagamet 400mg Tablet (GlaxoSmithKline UK Ltd) CPRD_product_code res25: gastroprotection drug
8388 Pepcid 20mg tablets (Merck Sharp & Dohme Ltd) CPRD_product_code res25: gastroprotection